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Last Modified: 11/20/2009     First Published: 12/9/2005  
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Phase III Randomized Study of Cetuximab and/or Bevacizumab in Combination With Either Oxaliplatin, Fluorouracil, and Leucovorin Calcium (FOLFOX) OR Irinotecan Hydrochloride, Fluorouracil, and Leucovorin Calcium (FOLFIRI) in Patients With Previously Untreated Metastatic Adenocarcinoma of the Colon or Rectum (Arm III [Cetuximab and Bevacizumab in Combination With FOLFOX or FOLFIRI] Closed to Accrual as of 09/10/2009)

Alternate Title
Basic Trial Information
Objectives
Entry Criteria
Expected Enrollment
Outcomes
Outline
Published Results
Related Publications
Trial Contact Information
Related Information
Registry Information

Alternate Title

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentActive18 and overNCICALGB-C80405
C80405, SWOG-C80405, NCT00265850

Special Category: NCI Web site featured trial, NCI - CMS pilot project trial, CTSU trial

Objectives

Primary

  1. Compare overall survival of patients with previously untreated metastatic colorectal cancer treated with cetuximab and/or bevacizumab in combination with either oxaliplatin, fluorouracil, and leucovorin calcium (FOLFOX) OR irinotecan hydrochloride, fluorouracil, and leucovorin calcium (FOLFIRI). (Arm III [cetuximab and bevacizumab in combination with FOLFOX or FOLFIRI] closed to accrual as of 09/10/2009)

Secondary

  1. Compare response, progression-free survival, time to treatment failure, and duration of response in patients with unresectable disease treated with these regimens.
  2. Compare toxicity and 60-day survival of patients with unresectable disease treated with these regimens.
  3. Determine whether patients with unresectable disease become eligible for surgical resection after treatment with these regimens.

Entry Criteria

Disease Characteristics:

  • Histologically or cytologically confirmed adenocarcinoma of the colon or rectum
    • Locally advanced (unresectable) or metastatic disease
      • Patients with resected primary tumors who have documented metastases are eligible
      • Separate histological or cytological confirmation is not required from patients with a history of colorectal cancer (previously treated by surgical resection) who have now developed radiological or clinical evidence of metastatic disease, unless 1 of the following is true:
        • An interval of > 5 years has elapsed between the primary surgery and the development of metastatic disease
        • The primary cancer was stage I

  • The intent of this treatment must be indicated as follows:
    • Palliative or neoadjuvant treatment with the potential for resection of all sites of metastatic disease

  • At least 1 paraffin block of previously resected primary tumor or tumor deposit available

  • Patients must have a wildtype K-ras gene

  • No known CNS metastases or carcinomatous meningitis

Prior/Concurrent Therapy:

Biologic therapy

  • No prior agents that target vascular endothelial growth factor (VEGF) or EGF receptors including protein products, monoclonal antibodies, or antisense therapies
  • No prior bevacizumab or cetuximab
  • No concurrent prophylactic filgrastim (G-CSF), pegfilgrastim, or sargramostim (GM-CSF)

Chemotherapy

  • See Radiotherapy
  • More than 12 months since prior adjuvant chemotherapy (≤ 6 months in duration) that included fluorouracil alone or in combination with oxaliplatin or irinotecan hydrochloride
  • No prior regional chemotherapy (e.g., hepatic arterial infusion)
  • No other concurrent chemotherapy

Endocrine therapy

  • No concurrent hormonal therapy except steroids for adrenal failure, hormones for noncancer-related conditions (e.g., insulin for diabetes), or intermittent dexamethasone as an antiemetic

Radiotherapy

  • Prior radiotherapy with radiosensitizing chemotherapy allowed
  • Prior standard adjuvant chemoradiotherapy for rectal cancer allowed
  • At least 4 weeks since prior radiotherapy
  • No prior radiotherapy to > 25% of bone marrow
  • No concurrent palliative radiotherapy except whole brain irradiation for documented CNS disease

Surgery

  • See Disease Characteristics
  • At least 4 weeks since prior major surgery
  • At least 2 weeks since prior minor surgery
    • Insertion of a vascular access device is not considered a prior surgery
  • Recovered from all prior surgery

Other

  • At least 4 weeks since prior itraconazole or ketoconazole
  • No prior tyrosine kinase inhibitor therapy
  • No prior systemic treatment for advanced or metastatic colorectal cancer
  • No concurrent aprepitant
  • Concurrent full-dose anticoagulation (i.e., warfarin) allowed provided all of the following criteria are met:
    • In-range INR (usually 2-3) on a stable dose of oral anticoagulant or stable dose of low molecular weight heparin
    • No active bleeding
    • No pathological condition with a high risk of bleeding (e.g., tumor involving major vessels or known varices)
  • Concurrent antiplatelet agents allowed
  • Concurrent daily prophylactic aspirin or anticoagulation for atrial fibrillation allowed

Patient Characteristics:

Performance status

  • ECOG 0-1

Life expectancy

  • Not specified

Hematopoietic

  • Granulocyte count ≥ 1,500/mm3
  • Platelet count ≥ 100,000/mm3
  • Hemoglobin ≥ 9.0 g/dL (transfusion allowed)
  • No history of significant bleeding episodes (e.g., hemoptysis or upper or lower gastrointestinal bleeding) within the past 6 months unless the source of bleeding has been resected

Hepatic

  • Bilirubin ≤ 1.5 mg/dL
  • Albumin ≥ 2.5 g/dL
  • No evidence of Gilbert's syndrome for patients assigned to receive FOLFIRI chemotherapy
    • Gilbert's syndrome allowed for patients assigned to receive FOLFOX chemotherapy

Renal

  • Creatinine ≤ 1.5 times upper limit of normal
  • Protein < 1+ by urinalysis
    • Protein < 1 g by 24-hour urine collection for patients with protein ≥ 2+ by urinalysis

Cardiovascular

  • No arterial thromboembolic event within the past 6 months, including any of the following:
    • Myocardial infarction
    • Transient ischemic attack
    • Cerebrovascular accident
    • Unstable angina or angina requiring surgical or medical intervention
  • No uncontrolled hypertension (i.e., blood pressure ≥ 160/90 on a regimen of antihypertensive therapy)
  • No New York Heart Association class II-IV congestive heart failure
  • No clinically significant peripheral artery disease (i.e., claudication on less than 1 block)

Pulmonary

  • No interstitial pneumonia
  • No extensive or symptomatic interstitial fibrosis of the lung
  • No pleural effusion or ascites that causes ≥ grade 2 dyspnea

Gastrointestinal

  • No gastrointestinal perforation within past year
  • No uncontrolled, predisposing colonic or small bowel disorder (i.e., > 3 watery or soft stools daily for patients without a colostomy or ileostomy)
    • Patients with a colostomy or ileostomy are eligible at the discretion of the investigator

Neurologic

  • No sensory peripheral neuropathy ≥ grade 2 for patients assigned to receive FOLFOX chemotherapy
  • No uncontrolled seizure disorder
  • No active neurological disease

Other

  • Not pregnant or nursing
  • Negative pregnancy test
  • Fertile patients must use effective contraception during and for at least 2-6 months after completion of study treatment
  • No serious nonhealing wound, ulcer, or bone fracture
  • No known hypersensitivity to Chinese hamster ovary cell products or recombinant human or murine antibodies
  • No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer or carcinoma in situ of the cervix

Expected Enrollment

2900

A total of 2,900 patients will be accrued for this study.

Outcomes

Primary Outcome(s)

Overall survival

Secondary Outcome(s)

Response (complete response and partial response)
Progression-free survival
Time to treatment failure
Duration of tumor response

Outline

This is a randomized, open-label, multicenter study. Patients are stratified according to physician-selected chemotherapy (oxaliplatin, leucovorin calcium, and fluorouracil [FOLFOX] vs irinotecan hydrochloride, leucovorin calcium, or fluorouracil [FOLFIRI]), prior adjuvant chemotherapy (yes vs no), and prior pelvic radiotherapy (yes vs no). Patients are randomized to 1 of 3 treatment arms. (Arm III closed to accrual as of 09/10/2009)

  • Arm I: Patients receive oxaliplatin IV over 2 hours or irinotecan hydrochloride IV over 30-90 minutes; leucovorin calcium IV over 2 hours; fluorouracil IV continuously over 46-48 hours; and bevacizumab IV over 30-90 minutes on days 1, 15, 29, and 43.

  • Arm II: Patients receive oxaliplatin or irinotecan hydrochloride, leucovorin calcium, and fluorouracil as in arm I. Patients also receive cetuximab IV over 1-2 hours on days 1, 8, 15, 22, 29, 36, 43, and 50.

  • Arm III (closed to accrual as of 09/10/2009): Patients receive oxaliplatin or irinotecan hydrochloride, leucovorin calcium, fluorouracil, and bevacizumab as in arm I. Patients also receive cetuximab as in arm II.

In all arms, treatment repeats every 56 days for at least 2 courses in the absence of disease progression, unacceptable toxicity, or planned surgery with curative intent.

For patients whom elective surgery is contemplated, bevacizumab must be discontinued for at least 8 weeks before surgery and may not be resumed for at least 4 weeks after surgery. Patients who undergo complete resection of metastatic disease are removed from study.

After completion of study treatment, patients are followed up every 2 months for 5 years and then every 6 months for 5 years.

Published Results

Venook AP, Blanke CD, Niedzwiecki D, et al.: Revisiting the Cancer and Leukemia Group B/Southwest Oncology Group 80405 Trial: a phase III trial of chemotherapy and biologic agents for patients with untreated advanced colorectal adenocarcinoma. Clin Colorectal Cancer 6 (7): 536-8, 2007.[PUBMED Abstract]

Venook AP, Blanke CD, Niedzwiecki D, et al.: Cancer and Leukemia Group B/Southwest Oncology Group trial 80405: a phase III trial of chemotherapy and biologics for patients with untreated advanced colorectal adenocarcinoma. Clin Colorectal Cancer 5 (4): 292-4, 2005.[PUBMED Abstract]

Related Publications

Schrag D, Naughton M, Kesselheim A, et al.: Clinical trial participants' strategies for coping with prescription drug costs: A companion study to CALGB 80405. [Abstract] J Clin Oncol 27 (Suppl 15): A-9503, 2009.

Trial Contact Information

Trial Lead Organizations

Cancer and Leukemia Group B

Alan Venook, MD, Protocol chair
Ph: 415-353-7065; 800-888-8664
Email: venook@cc.ucsf.edu

Southwest Oncology Group

Charles Blanke, MD, FACP, Protocol chair
Ph: 604-877-6098 ext. 2738; 800-663-3333

Trial Sites

U.S.A.
Alabama
  Mobile
 Providence Cancer Center at Providence Hospital
 Thaddeus Beeker
Ph: 251-633-1890
Arkansas
  Ft. Smith
 Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
 John Wells, MD
Ph: 479-484-4700
California
  Burbank
 Providence Saint Joseph Medical Center - Burbank
 Clinical Trials Office - Providence Saint Joseph Medical Center - Burbank
Ph: 818-847-3220
  Castro Valley
 East Bay Radiation Oncology Center
 James Feusner, MD
Ph: 510-428-3689
 Valley Medical Oncology Consultants - Castro Valley
 James Feusner, MD
Ph: 510-428-3689
  Duarte
 City of Hope Comprehensive Cancer Center
 Clinical Trials Office - City of Hope Comprehensive Cancer Center
Ph: 800-826-4673
 Email: becomingapatient@coh.org
  Fremont
 Kaiser Permanente - Fremont
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Valley Medical Oncology
 James Feusner, MD
Ph: 510-428-3689
  Glendale
 Glendale Memorial Hospital Comprehensive Cancer Center
 Clinical Trials Office - Glendale Memorial Hospital Comprehensive Cancer Center
Ph: 818-409-7653
  Greenbrae
 California Cancer Care, Incorporated - Greenbrae
 Peter Eisenberg, MD
Ph: 415-925-5000
  Hayward
 Kaiser Permanente Medical Center - Hayward
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Los Angeles
 USC/Norris Comprehensive Cancer Center and Hospital
 Clinical Trials Office - USC/Norris Comprehensive Cancer Center and Hospital
Ph: 323-865-0451
  Martinez
 Contra Costa Regional Medical Center
 James Feusner, MD
Ph: 510-428-3689
  Mountain View
 Camino Medical Group - Treatment Center
 Peter Yu, MD
Ph: 408-524-5814
  Oakland
 Alta Bates Summit Medical Center - Summit Campus
 Clinical Trials Office - Alta Bates Summit Medical Center - Summit Campus
Ph: 510-204-1414
 Bay Area Breast Surgeons, Incorporated
 James Feusner, MD
Ph: 510-428-3689
 Highland General Hospital
 James Feusner, MD
Ph: 510-428-3689
 Kaiser Permanente Medical Center - Oakland
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Larry G Strieff MD Medical Corporation
 James Feusner, MD
Ph: 510-428-3689
 Tom K Lee, Incorporated
 James Feusner, MD
Ph: 510-428-3689
  Palo Alto
 Palo Alto Medical Foundation
 Peter Yu, MD
Ph: 408-524-5814
  Pleasanton
 Valley Medical Oncology Consultants - Pleasanton
 James Feusner, MD
Ph: 510-428-3689
  Redwood City
 Kaiser Permanente Medical Center - Redwood City
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Richmond
 Kaiser Permanente Medical Center - Richmond
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Roseville
 Kaiser Permanente Medical Center - Roseville
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Sacramento
 Kaiser Permanente Medical Center - Sacramento
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 South Sacramento Kaiser-Permanente Medical Center
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  San Diego
 Kaiser Permanente Medical Office -Vandever Medical Office
 Han Koh
Ph: 619-528-2596
  San Francisco
 Kaiser Permanente Medical Center - San Francisco Geary Campus
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 UCSF Helen Diller Family Comprehensive Cancer Center
 Clinical Trials Office - UCSF Helen Diller Family Comprehensive Cancer Center
Ph: 877-827-3222
  San Jose
 Kaiser Permanente Medical Center - Santa Teresa
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  San Rafael
 Kaiser Foundation Hospital - San Rafael
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Santa Clara
 Kaiser Permanente Medical Center - Santa Clara Kiely Campus
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Santa Rosa
 Kaiser Permanente Medical Center - Santa Rosa
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  South San Francisco
 Kaiser Permanente Medical Center - South San Francisco
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Stockton
 Kaiser Permanente Medical Facility - Stockton
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Vallejo
 Kaiser Permanente Medical Center - Vallejo
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Walnut Creek
 Kaiser Permanente Medical Center - Walnut Creek
 Louis Fehrenbacher, MD
Ph: 707-651-2577
Colorado
  Aurora
 Aurora Presbyterian Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 University of Colorado Cancer Center at UC Health Sciences Center
 Clinical Trials Office - University of Colorado Cancer Center
Ph: 720-848-0650
  Boulder
 Boulder Community Hospital
 Clinical Trials Office - Boulder Community Hospital
Ph: 303-938-5253
  Colorado Springs
 Penrose Cancer Center at Penrose Hospital
 Clinical Trials Office - Penrose Cancer Center
Ph: 719-776-5275
  Denver
 CCOP - Colorado Cancer Research Program
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Denver Health Medical Center
 Wells Messersmith, MD
Ph: 410-502-6873
 Porter Adventist Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Presbyterian - St. Luke's Medical Center
 Clinical Trials Office - Presbyterian - St. Luke's Medical Center
Ph: 303-839-6000
 Rose Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Anthony Central Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Joseph Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Veterans Affairs Medical Center - Denver
 Wells Messersmith, MD
Ph: 410-502-6873
  Edwards
 Shaw Regional Cancer Center
 Wells Messersmith, MD
Ph: 410-502-6873
  Englewood
 Swedish Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Fort Collins
 Front Range Cancer Specialists
 Robert Marschke, Jr.
Ph: 970-212-7600
 Poudre Valley Hospital
 Clinical Trials Office - Poudre Valley Hospital
Ph: 970-495-8226
  Grand Junction
 St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Greeley
 North Colorado Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Lone Tree
 Sky Ridge Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Longmont
 Hope Cancer Care Center at Longmont United Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Loveland
 McKee Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Montrose
 Montrose Memorial Hospital Cancer Center
 Clinical Trials Office - Montrose Memorial Hospital Cancer Center
Ph: 670-240-7267
  Pueblo
 St. Mary - Corwin Regional Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Thornton
 North Suburban Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Wheat Ridge
 Exempla Lutheran Medical Center
 Clinical Trials Office - Exempla Lutheran Medical Center
Ph: 303-403-3605
Connecticut
  Greenwich
 Bendheim Cancer Center at Greenwich Hospital
 Clinical Trials Office - Bendheim Cancer Center
Ph: 203-863-3698
  New Britain
 George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus
 Clinical Trials Office - George Bray Cancer Center
Ph: 860-224-5660
  Norwich
 Eastern Connecticut Hematology and Oncology Associates
 Dennis Slater, MD
Ph: 860-886-8362
Delaware
  Dover
 Kent General Hospital
 Iftekhar Khan, MD
Ph: 302-430-5072
  Lewes
 Tunnell Cancer Center at Beebe Medical Center
 Clinical Trials Office - Tunnell Cancer Center
Ph: 302-645-3171
  Newark
 CCOP - Christiana Care Health Services
 Clinical Trial Office - CCOP - Christiana Care Health Services
Ph: 302-733-6227
District of Columbia
  Washington
 Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
 Clinical Trials Office - Lombardi Comprehensive Cancer Center
Ph: 202-444-0381
 Veterans Affairs Medical Center - Washington, DC
 Robert Wadleigh
Ph: 202-745-8178
888-553-0242
Florida
  Boca Raton
 Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus
 Clinical Trials Office - Eugene M. and Christine E. Lynn Cancer Institute
Ph: 561-955-4800
  Fort Lauderdale
 Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
 Clinical Trials Office - Michael and Dianne Bienes Comprehensive Cancer Center
Ph: 954-776-3239
  Jupiter
 Ella Milbank Foshay Cancer Center at Jupiter Medical Center
 Clinical Trials Office - Ella Milbank Foshay Cancer Center
Ph: 561-745-5768
  Leesburg
 Cancer Centers of Central Florida, PA
 Glenn Mills, MD
Ph: 318-813-1440
  Miami Beach
 CCOP - Mount Sinai Medical Center
 Joseph Pizzolato
Ph: 305-674-2625
  Orlando
 Florida Hospital Cancer Institute at Florida Hospital Orlando
 Clinical Trials Office - Florida Hospital Cancer Institute
Ph: 407-303-5623
  Titusville
 Space Coast Medical Associates
 Ashish Dalal
Ph: 321-268-4200
  Weston
 Cleveland Clinic Florida - Weston
 Clinical Trials Office - Cleveland Clinic Florida - Weston
Ph: 954-659-5705
Georgia
  Albany
 Phoebe Cancer Center at Phoebe Putney Memorial Hospital
 Clinical Trials Office - Phoebe Cancer Center
Ph: 229-312-2251
  Athens
 Northeast Georgia Cancer Care, LLC - Medical Oncology
 Clinical Trials Office - Northeast Georgia Cancer Care, LLC
Ph: 706-353-5006
  Atlanta
 CCOP - Atlanta Regional
 Thomas Seay, MD, PhD
Ph: 404-851-2340
 Northside Hospital Cancer Center
 Clinical Trials Office - Northside Hospital Cancer Center
Ph: 404-303-3355
 Piedmont Hospital
 Thomas Seay, MD, PhD
Ph: 404-851-2340
 Saint Joseph's Hospital of Atlanta
 Clinical Trials Office - Saint Joseph's Hospital of Atlanta
Ph: 404-851-7115
  Augusta
 MBCCOP - Medical College of Georgia Cancer Center
 Anand Jillella, MD
Ph: 706-721-2505
  Austell
 WellStar Cobb Hospital
 Clinical Trials Office - WellStar Cobb Hospital
Ph: 770-793-5980
  Decatur
 Charles B. Eberhart Cancer Center at DeKalb Medical Center
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Gainesville
 Northeast Georgia Medical Center
 Richard LoCicero, MD
Ph: 770-297-5700
  Lawrenceville
 Gwinnett Medical Center
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Macon
 Medical Center of Central Georgia
 Frederick Schnell, MD, FACP
Ph: 478-743-7068
  Marietta
 Kennestone Cancer Center at Wellstar Kennestone Hospital
 Clinical Trials Office - Kennestone Cancer Center
Ph: 770-793-5980
  Riverdale
 Southern Regional Medical Center
 Clinical Trials Office - Southern Regional Medical Center
Ph: 770-991-8611
  Savannah
 Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
 Clinical Trials Office - Curtis and Elizabeth Anderson Cancer Institute
Ph: 912-350-8568
 Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
 Mark Taylor, MD
Ph: 912-354-6187
Hawaii
  Honolulu
 Tripler Army Medical Center
 Jeffrey Berenberg, MD
Ph: 808-433-4089
Idaho
  Boise
 Mountain States Tumor Institute at St. Luke's Regional Medical Center
 Theodore Walters, MD
Ph: 208-381-2711
Illinois
  Alton
 Saint Anthony's Hospital at Saint Anthony's Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Chicago
 Creticos Cancer Center at Advocate Illinois Masonic Medical Center
 Clinical Trials Office - Creticos Cancer Center at Advocate Illinois Masonic Medical Center
Ph: 773-296-5360
 Louis A. Weiss Memorial Hospital
 Clinical Trials Office - Louis A. Weiss Memorial Hospital
Ph: 773- 564-5044
 Robert H. Lurie Comprehensive Cancer Center at Northwestern University
 Clinical Trials Office - Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Ph: 312-695-1301
 Email: cancer@northwestern.edu
 University of Chicago Cancer Research Center
 Clinical Trials Office - University of Chicago Cancer Research Center
Ph: 773-834-7424
  Decatur
 Decatur Memorial Hospital Cancer Care Institute
 Clinical Trials Office - Decatur Memorial Hospital Cancer Care Institute
Ph: 217-876-6601
  Joliet
 Joliet Oncology-Hematology Associates, Limited - West
 Sanjiv Modi
Ph: 815-730-3098
  Kankakee
 Provena St. Mary's Regional Cancer Center - Kankakee
 Riaz Elahi, MD
Ph: 708-873-4500
  La Grange
 La Grange Memorial Hospital
 Clinical Trials Office - La Grange Memorial Hospital
Ph: 630-856-7526
  Mt. Vernon
 Good Samaritan Regional Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Naperville
 Edward Hospital Cancer Center
 Clinical Trials Office - Edward Hospital Cancer Center
Ph: 630-646-6075
  Niles
 Cancer Care and Hematology Specialists of Chicagoland - Niles
 Mary Mulcahy, MD
Ph: 312-695-6180
  Rockford
 Center for Cancer Care at OSF Saint Anthony Medical Center
 Clinical Trials Office - Center for Cancer Care at OSF Saint Anthony Medical Center
Ph: 815-227-2633
 Swedish-American Regional Cancer Center
 Clinical Trials Office - Swedish-American Regional Cancer Center
Ph: 815-489-4413
Indiana
  Beech Grove
 St. Francis Hospital and Health Centers - Beech Grove Campus
 Howard Gross, MD
Ph: 937-832-1093
  Elkhart
 Elkhart General Hospital
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  Fort Wayne
 Fort Wayne Medical Oncology and Hematology
 Sreenivasa Nattam, MD
Ph: 260-484-8830
  Indianapolis
 St. Vincent Indianapolis Hospital
 Clinical Trials Office - St. Vincent Indianapolis Hospital
Ph: 317-338-2194
  Kokomo
 Howard Community Hospital
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  La Porte
 Center for Cancer Therapy at LaPorte Hospital and Health Services
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  Lafayette
 Clarian Arnett Cancer Care
 Thomas Jones, MD
Ph: 765-448-7500
  Merrillville
 Suniti Medical Corporation
 Bharat Barai, MD
Ph: 219-736-2800
  Richmond
 Reid Hospital & Health Care Services
 Howard Gross, MD
Ph: 937-832-1093
  South Bend
 CCOP - Northern Indiana CR Consortium
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
 Memorial Hospital of South Bend
 Clinical Trials Office - Memorial Hospital of South Bend
Ph: 800-284-7370
 Saint Joseph Regional Medical Center
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
 South Bend Clinic
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
Iowa
  Ames
 McFarland Clinic, PC
 Clinical Trials Office - McFarland Clinic, PC
Ph: 515-239-2621
  Cedar Rapids
 Cedar Rapids Oncology Associates
 Clinical Trials Office - Cedar Rapids Oncology Associates
Ph: 319-363-2690
 Iowa Blood and Cancer Care
 David Zenk, MD
Ph: 319-369-7091
 Mercy Regional Cancer Center at Mercy Medical Center
 David Zenk, MD
Ph: 319-369-7091
 St. Luke's Hospital
 David Zenk, MD
Ph: 319-369-7091
  Davenport
 Genesis Regional Cancer Center at Genesis Medical Center
 George Kovach, MD
Ph: 563-421-1960
  Des Moines
 CCOP - Iowa Oncology Research Association
 Robert Behrens
Ph: 515-244-7586
888-244-6061
 John Stoddard Cancer Center at Iowa Lutheran Hospital
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Lutheran Hospital
Ph: 515-241-8704
 John Stoddard Cancer Center at Iowa Methodist Medical Center
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Methodist Medical Center
Ph: 515-241-6727
 Medical Oncology and Hematology Associates at John Stoddard Cancer Center
 Robert Behrens
Ph: 515-282-2921
 Medical Oncology and Hematology Associates at Mercy Cancer Center
 Robert Behrens
Ph: 515-643-8740
 Mercy Cancer Center at Mercy Medical Center - Des Moines
 Robert Behrens
Ph: 515-643-8206
888-221-4849
  Iowa City
 Holden Comprehensive Cancer Center at University of Iowa
 Cancer Information Service
Ph: 800-237-1225
  Mason City
 Mercy Cancer Center at Mercy Medical Center - North Iowa
 Clinical Trials Office - Mercy Cancer Center at Mercy Medical Center - North Iowa
Ph: 641-422-6304
  Ottumwa
 McCreery Cancer Center at Ottumwa Regional
 Robert Behrens
Ph: 641-684-2946
  Sioux City
 Mercy Medical Center - Sioux City
 Donald Wender, MD, PhD
Ph: 712-252-0088
 Siouxland Hematology-Oncology Associates, LLP
 Donald Wender, MD, PhD
Ph: 712-252-0088
 St. Luke's Regional Medical Center
 Donald Wender, MD, PhD
Ph: 712-252-0088
  Waterloo
 Covenant Cancer Treatment Center
 Clinical Trials Office - Covenant Cancer Treatment Center
Ph: 319-272-2070
Kansas
  Kansas City
 Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
 Clinical Trials Office - Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
Ph: 913-588-4709
  Overland Park
 Menorah Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
 Saint Luke's Hospital - South
 Rakesh Gaur, MD
Ph: 816-823-0555
  Shawnee Mission
 Shawnee Mission Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
Kentucky
  Louisville
 James Graham Brown Cancer Center at University of Louisville
 Vivek Sharma
Ph: 502-562-4158
866-530-5516
Louisiana
  Baton Rouge
 Mary Bird Perkins Cancer Center - Baton Rouge
 Robert Veith
Ph: 225-767-0847
 Ochsner Health Center - Bluebonnet
 Jyotsna Fuloria
Ph: 225-761-5200
 Pennington Cancer Center at Baton Rouge General
 Clinical Trials Office - Pennington Cancer Center at Baton Rouge General
Ph: 225-381-6451
  Mansfield
 DeSoto Regional Hospital
 Glenn Mills, MD
Ph: 318-813-1440
  Monroe
 Louisiana State University Health Sciences Center - Monroe
 Glenn Mills, MD
Ph: 318-813-1440
  New Orleans
 CCOP - Ochsner
 Jyotsna Fuloria
Ph: 504-842-3910
 MBCCOP - LSU Health Sciences Center
 Robert Veith
Ph: 504-568-5151
 Medical Center of Louisiana - New Orleans
 Robert Veith
Ph: 504-903-2311
 Ochsner Cancer Institute at Ochsner Clinic Foundation
 Jyotsna Fuloria
Ph: 504-842-4360
888-624-7637
  Shreveport
 Christus Schumpert Cancer Treatment Center
 Clinical Trials Office - Christus Schumpert Cancer Treatment Center
Ph: 318-681-4763
 Feist-Weiller Cancer Center at Louisiana State University Health Sciences
 Clinical Trials Office - Feist-Weiller Cancer Center at Louisiana State University Health Sciences
Ph: 318-813-1412
 Highland Clinic
 Glenn Mills, MD
Ph: 318-813-1440
Maine
  Bangor
 CancerCare of Maine at Eastern Maine Medical Center
 Clinical Trials Office - CancerCare of Maine
Ph: 207-973-4274
  Portland
 Mercy Hospital
 Roger Inhorn, MD, PhD
Ph: 207-879-3030
  Waterville
 MaineGeneral Medical Center - Waterville
 Clinical Trials Office - MaineGeneral Medical Center - Waterville
Ph: 207-872-1792
  York
 York Hospital's Oncology Treatment Center
 Jonathan Eneman
Ph: 207-351-3777
Maryland
  Baltimore
 Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
 Clinical Trials Office - Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
Ph: 443-777-7364
  Easton
 Shore Regional Cancer Center at Memorial Hospital - Easton
 Mary DeShields, MD
Ph: 410-819-3332
  Elkton MD
 Union Hospital Cancer Program at Union Hospital
 Stephen Grubbs, MD
Ph: 302-366-1200
  Frederick
 Frederick Memorial Hospital Regional Cancer Therapy Center
 Paul Rausch, MD
Ph: 301-662-8477
  Hagerstown
 John R. Marsh Cancer Center at Washington County Hospital
 Michael McCormack
Ph: 301-665-4650
  Salisbury
 Peninsula Regional Medical Center
 Clinical Trials Office - Peninsula Regional Medical Center
Ph: 410-543-7000
Massachusetts
  Concord
 Commonwealth Hematology-Oncology, PC - Concord
 Susan Sajer, MD
Ph: 978-287-3436
  Gloucester
 Addison Gilbert Hospital
 Angus McIntyre, MD
Ph: 978-927-6850
  Lawrence
 Commonwealth Hematology-Oncology, PC - Lawrence
 Susan Sajer, MD
Ph: 978-287-3436
  Peabody
 NSMC Cancer Center - Peabody
 Lauren Dias
Ph: 978-977-3434
  Pittsfield
 Berkshire Hematology Oncology, PC
 Harvey Zimbler, MD
Ph: 413-496-8205
  Quincy
 Commonwealth Hematology-Oncology, PC - Quincy
 Susan Sajer, MD
Ph: 978-287-3436
  Stoneham
 Commonwealth Hematology-Oncology, PC - Stoneham
 Susan Sajer, MD
Ph: 978-287-3436
  Weymouth
 Commonwealth Hematology-Oncology, PC - Weymouth
 Susan Sajer, MD
Ph: 978-287-3436
  Worcester
 Commonwealth Hematology-Oncology, PC - Worcester
 Susan Sajer, MD
Ph: 978-287-3436
Michigan
  Adrian
 Hickman Cancer Center at Bixby Medical Center
 Clinical Trials Office - Hickman Cancer Center at Bixby Medical Center
Ph: 517-265-0116
  Ann Arbor
 CCOP - Michigan Cancer Research Consortium
 Philip Stella, MD
Ph: 734-712-1000
 Saint Joseph Mercy Cancer Center
 Philip Stella, MD
Ph: 734-712-1000
  Battle Creek
 Battle Creek Health System Cancer Care Center
 Martin Bury
Ph: 616-966-8000
  Big Rapids
 Mecosta County Medical Center
 Martin Bury
Ph: 231-796-8691
  Dearborn
 Oakwood Cancer Center at Oakwood Hospital and Medical Center
 Clinical Trials Office - Oakwood Cancer Center at Oakwood Hospital and Medical Center
Ph: 313-593-8090
  Escanaba
 Green Bay Oncology, Limited - Escanaba
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
  Flint
 Genesys Hurley Cancer Institute
 Clinical Trials Office - Genesys Hurley Cancer Institute
Ph: 810-762-8057
 Hurley Medical Center
 Clinical Trials Office - Hurley Medical Center
Ph: 810-762-8057
  Grand Rapids
 Butterworth Hospital at Spectrum Health
 Martin Bury
Ph: 616-391-2799
 CCOP - Grand Rapids
 Martin Bury
Ph: 616-391-1230
 Lacks Cancer Center at Saint Mary's Health Care
 Martin Bury
Ph: 616-752-5222
  Grosse Pointe Woods
 Van Elslander Cancer Center at St. John Hospital and Medical Center
 Clincial Trials Office - Van Elslander Cancer Center at St. John Hospital and Medical Center
Ph: 313-343-3166
  Iron Mountain
 Dickinson County Healthcare System
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
  Jackson
 Foote Memorial Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Kalamazoo
 Borgess Medical Center
 Raymond Lord, MD
Ph: 269-373-7458
 Bronson Methodist Hospital
 Raymond Lord, MD
Ph: 269-373-7458
 West Michigan Cancer Center
 Clinical Trials Office - West Michigan Cancer Center
Ph: 269-373-7458
  Lambertville
 Haematology-Oncology Associates of Ohio and Michigan, PC
 Paul Schaefer, MD
Ph: 419-479-5605
  Lansing
 Sparrow Regional Cancer Center
 Clinical Trials Office - Sparrow Regional Cancer Center
Ph: 517-364-2890
  Livonia
 St. Mary Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Monroe
 Community Cancer Center of Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
 Mercy Memorial Hospital - Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
  Muskegon
 Mercy General Health Partners
 Martin Bury
Ph: 231-672-2000
  Pontiac
 St. Joseph Mercy Oakland
 Philip Stella, MD
Ph: 734-712-1000
  Port Huron
 Mercy Regional Cancer Center at Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Saginaw
 Seton Cancer Institute at Saint Mary's - Saginaw
 Clinical Trials Office - Seton Cancer Institute - Saginaw
Ph: 989-776-8411
  Saint Joseph
 Oncology Care Associates, PLLC
 Eric Lester, MD
Ph: 269-985-0029
  Southfield
 Providence Cancer Institute at Providence Hospital - Southfield Campus
 Anibal Drelichman, MD, MPH, FACP
Ph: 313-552-0620
  St. Joseph
 Lakeland Regional Cancer Care Center - St. Joseph
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  Traverse City
 Munson Medical Center
 Martin Bury
Ph: 231-935-6202
  Warren
 St. John Macomb Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Wyoming
 Metro Health Hospital
 Martin Bury
Ph: 616-252-7200
Minnesota
  Alexandria
 Donald Jurgens
Ph: 320-229-4907
  Bemidji
 MeritCare Bemidji
 Preston Steen, MD
Ph: 701-234-2397
  Duluth
 CCOP - Duluth
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 Duluth Clinic Cancer Center - Duluth
 Clinical Trials Office - Duluth Clinic Cancer Center - Duluth
Ph: 218-786-3308
 Miller - Dwan Medical Center
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
  Edina
 Fairview Southdale Hospital
 Clinical Trials Office - Fairview Southdale Hospital
Ph: 612-625-3650
  Mankato
 Immanuel St. Joseph's
 Glenn Harman, MD
Ph: 815-777-1536
  Saint Cloud
 CentraCare Clinic - River Campus
 Donald Jurgens
Ph: 320-229-4907
 Coborn Cancer Center
 Donald Jurgens
Ph: 320-229-4907
Mississippi
  Hattiesburg
 Hattiesburg Clinic, PA at Forrest General
 Jyotsna Fuloria
Ph: 601-288-8282
 Hematology & Oncology Clinic
 Jyotsna Fuloria
Ph: 601-268-5150
  Kessler AFB
 Keesler Air Force Base Medical Center
 Louis Varner
Ph: 228-377-2086
  Pascagoula
 Regional Cancer Center at Singing River Hospital
 James Clarkson, MD
Ph: 228-374-6296
Missouri
  Cape Girardeau
 Saint Francis Medical Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Chesterfield
 Saint Luke's Hospital
 Donald Busiek, MD
Ph: 314-205-6737
  Columbia
 Ellis Fischel Cancer Center at University of Missouri - Columbia
 Clinical Trial Office - Ellis Fischel Cancer Center
Ph: 573-882-7440
  Jefferson City
 Goldschmidt Cancer Center
 Juergen Bertram
Ph: 573-632-5482
  Joplin
 Freeman Cancer Institute at Freeman Health System
 Anisa Hassan
Ph: 417-347-3066
  Kansas City
 CCOP - Kansas City
 Rakesh Gaur, MD
Ph: 816-823-0555
 North Kansas City Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
 Parvin Radiation Oncology
 Rakesh Gaur, MD
Ph: 816-823-0555
 Research Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
 Saint Luke's Cancer Institute at Saint Luke's Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
 St. Joseph Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
 Truman Medical Center - Hospital Hill
 Rakesh Gaur, MD
Ph: 816-823-0555
  Lee's Summit
 Saint Luke's East - Lee's Summit
 Rakesh Gaur, MD
Ph: 816-823-0555
  Liberty
 Liberty Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
  Saint Joseph
 Heartland Regional Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Saint Louis
 CCOP - St. Louis-Cape Girardeau
 Bethany Sleckman, MD
Ph: 314-251-7057
 David C. Pratt Cancer Center at St. John's Mercy
 Clinical Trials Office - David C. Pratt Cancer Center at St. John's Mercy
Ph: 314-251-6770
 Midwest Hematology Oncology Group, Incorporated
 Bethany Sleckman, MD
Ph: 314-251-7057
 Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
 Joel Picus, MD
Ph: 314-362-5737
  Springfield
 CCOP - Cancer Research for the Ozarks
 Robert Carolla
Ph: 417-269-4520
 St. John's Regional Health Center
 Robert Carolla
Ph: 417-820-2000
Montana
  Billings
 Billings Clinic - Downtown
 Clinical Trials Office - Billings Clinic - Downtown
Ph: 800-996-2663
 Email: research@billingsclinic.org
 CCOP - Montana Cancer Consortium
 Benjamin Marchello, MD
Ph: 406-238-6290
 Hematology-Oncology Centers of the Northern Rockies - Billings
 Benjamin Marchello, MD
Ph: 406-238-6290
 Northern Rockies Radiation Oncology Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 St. Vincent Healthcare Cancer Care Services
 Benjamin Marchello, MD
Ph: 406-238-6290
  Bozeman
 Bozeman Deaconess Cancer Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Butte
 St. James Healthcare Cancer Care
 Benjamin Marchello, MD
Ph: 406-238-6290
  Great Falls
 Benjamin Marchello, MD
Ph: 406-238-6290
 Big Sky Oncology
 Clinical Trail Office - Big Sky Oncology
Ph: 406-731-8217
 Great Falls Clinic - Main Facility
 Benjamin Marchello, MD
Ph: 406-238-6290
 Sletten Cancer Institute at Benefis Healthcare
 Grant Harrer, MD, FACP, CCTI
Ph: 406-731-8100
  Havre
 Northern Montana Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Helena
 St. Peter's Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Kalispell
 Glacier Oncology, PLLC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Medical Oncology at KRMC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Regional Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Missoula
 Community Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 Guardian Oncology and Center for Wellness
 Benjamin Marchello, MD
Ph: 406-238-6290
 Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
 Clinical Trials Office - Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
Ph: 406-329-7029
 Montana Cancer Specialists at Montana Cancer Center
 Clinical Trials Office - Montana Cancer Specialists at Montana Cancer Center
Ph: 406-238-6962
Nebraska
  Grand Island
 Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center
 Jean Grem, MD
Ph: 402-559-6210
  Kearney
 Good Samaritan Cancer Center at Good Samaritan Hospital
 Clinical Trials Office - Good Samaritan Cancer Center at Good Samaritan Hospital
Ph: 308-865-7963
  Lincoln
 Cancer Resource Center - Lincoln
 Alan Berg, MD
Ph: 402-420-7000
  North Platte
 Callahan Cancer Center at Great Plains Regional Medical Center
 Clinical Trials Office - Callahan Cancer Center at Great Plains Regional Medical Center
Ph: 308-696-7864
  Omaha
 Alegant Health Cancer Center at Bergan Mercy Medical Center
 Clinical Trials Office - Alegant Health Cancer Center at Bergen Mercy Medical Center
Ph: 402-398-6060
 CCOP - Missouri Valley Cancer Consortium
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Creighton University Medical Center
 Clinical Trials Office - Creighton University Medical Center
Ph: 402-280-4100
 Immanuel Medical Center
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Methodist Estabrook Cancer Center
 Robert Langdon, MD
Ph: 402-399-8762
 UNMC Eppley Cancer Center at the University of Nebraska Medical Center
 Clinical Trials Office - UNMC Eppley Cancer Center at the University of Nebraska Medical Center
Ph: 800-999-5465
Nevada
  Las Vegas
 CCOP - Nevada Cancer Research Foundation
 John Ellerton, MD, CM
Ph: 702-384-0013
 Nevada Cancer Institute
 Clinical Trials Office - Nevada Cancer Institute
Ph: 702-822-5136
 University Medical Center of Southern Nevada
 John Ellerton, MD, CM
Ph: 702-384-0013
  Reno
 Renown Institute for Cancer at Renown Regional Medical Center
 Steven Schiff, MD
Ph: 775-329-0873
New Hampshire
  Concord
 New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
 Charles Catcher, MD
Ph: 603-224-2556
  Exeter
 Center for Cancer Care at Exeter Hospital
 Danny Sims
Ph: 603-580-6636
  Hooksett
 New Hampshire Oncology - Hematology, PA - Hooksett
 Charles Catcher, MD
Ph: 603-224-2556
  Manchester
 Elliot Regional Cancer Center at Elliot Hospital
 Douglas Weckstein, MD
Ph: 603-622-6484
New Jersey
  Flemington
 Hunterdon Regional Cancer Center at Hunterdon Medical Center
 Kenneth Blankstein, MD
Ph: 908-788-6100
  Freehold
 CentraState Medical Center
 Jeffrey Silberberg, MD
Ph: 732-431-8400
  Livingston
 St. Barnabas Medical Center Cancer Center
 Clinical Trials Office - St. Barnabas Medical Center Cancer Center
Ph: 973-322-2470
  Marlton
 Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton
 Clinical Trials Office - Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton
Ph: 888-847-8823
  Sparta
 Frederick R. and Betty M. Smith Cancer Treatment Center
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Voorhees
 Cancer Institute of New Jersey at Cooper - Voorhees
 Clinical Trials Office - Cancer Institute of New Jersey at Cooper University Hospital - Voorhees
Ph: 856-325-6757
 Fox Chase Virtua Health Cancer Program at Virtua West Jersey
 Michael Entmacher, MD
Ph: 609-702-1900
New Mexico
  Albuquerque
 Hematology Oncology Associates, PC
 Fa-Chyi Lee, MD
Ph: 505-272-4175
 Lovelace Medical Center - Downtown
 Fa-Chyi Lee, MD
Ph: 505-272-4175
 Presbyterian Cancer Treatment Center at Presbyterian Kaseman Hospital
 Fa-Chyi Lee, MD
Ph: 505-272-4175
 University of New Mexico Cancer Center
 Clinical Trials Office - University of New Mexico Cancer Center
Ph: 505-272-6972
New York
  Brooklyn
 Coney Island Hospital
 Jack Burton
Ph: 718-616-3000
  Buffalo
 Veterans Affairs Medical Center - Buffalo
 Lynn Steinbrenner, MD
Ph: 716-862-3191
  Manhasset
 CCOP - North Shore University Hospital
 Bhoomi Mehrotra, MD
Ph: 718-470-8934
 Don Monti Comprehensive Cancer Center at North Shore University Hospital
 Clinical Trials Office - Don Monti Comprehensive Cancer Center at North Shore University Hospital
Ph: 516-734-8900
  Mount Kisco
 Northern Westchester Hospital
 Jonathan Goldberg
Ph: 914-666-1200
  New Hyde Park
 Long Island Jewish Medical Center
 Bhoomi Mehrotra, MD
Ph: 718-470-8934
  Syracuse
 SUNY Upstate Medical University Hospital
 Clinical Trials Office - SUNY Upstate Medical University Hospital
Ph: 315-464-5476
  Utica
 Faxton Regional Cancer Center
 Atul Butala, MD, FACP
Ph: 315-798-9300
North Carolina
  Asheville
 Mission Hospitals - Memorial Campus
 Clinical Trials Office - Mission Hospitals - Memorial Campus
Ph: 828-213-4150
  Burlington
 Alamance Cancer Center at Alamance Regional Medical Center
 Janak Choksi, MD
Ph: 336-538-7737
  Chapel Hill
 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
 Clinical Trials Office - Lineberger Comprehensive Cancer Center
Ph: 877-668-0683; 919-966-4432
  Charlotte
 Presbyterian Cancer Center at Presbyterian Hospital
 Clinical Trials Office - Presbyterian Cancer Center at Presbyterian Hospital
Ph: 704-384-5369
  Gastonia
 CaroMont Cancer Center at Gaston Memorial Hospital
 Clinical Trials Office - CaroMont Cancer Center at Gaston Memorial Hospital
Ph: 704-834-2932
  Goldsboro
 Southeastern Medical Oncology Center - Goldsboro
 James Atkins, MD
Ph: 919-580-0000
 Wayne Memorial Hospital, Incorporated
 James Atkins, MD
Ph: 919-580-0000
  Kinston
 Kinston Medical Specialists
 Peter Watson, MD
Ph: 252-559-2200ext.201
  Raleigh
 Rex Cancer Center at Rex Hospital
 Clinical Trials Office - Rex Cancer Center
Ph: 919-784-7209
  Rutherfordton
 Rutherford Hospital
 James Bearden, MD
Ph: 864-560-6812
  Washington
 Marion L. Shepard Cancer Center at Beaufort County Hospital
 Jennie Crews
Ph: 252-975-4308
  Wilmington
 Zimmer Cancer Center at New Hanover Regional Medical Center
 Cyrus Kotwall, MD
Ph: 910-763-4630
  Winston-Salem
 Wake Forest University Comprehensive Cancer Center
 Clinical Trials Office - Wake Forest University Comprehensive Cancer Center
Ph: 336-713-6771
North Dakota
  Bismarck
 Bismarck Cancer Center
 Edward Wos, DO
Ph: 701-323-5741
 Medcenter One Hospital Cancer Care Center
 Edward Wos, DO
Ph: 701-323-5741
 Mid Dakota Clinic, PC
 Clinical Trials Office - Mid Dakota Clinic, PC
Ph: 701-530-6950
 St. Alexius Medical Center Cancer Center
 Clinical Trials Office - St. Alexius Medical Center Cancer Center
Ph: 701-530-6950
  Fargo
 CCOP - MeritCare Hospital
 Preston Steen, MD
Ph: 701-234-2397
 MeritCare Broadway
 Preston Steen, MD
Ph: 701-234-2397
  Grand Forks
 Altru Cancer Center at Altru Hospital
 Clinical Trails Office - Altru Cancer Center at Altru Hospital
Ph: 701-780-6520
Ohio
  Akron
 McDowell Cancer Center at Akron General Medical Center
 Esther Rehmus, MD
Ph: 330-344-6505
  Bellefontaine
 Mary Rutan Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Bowling Green
 Wood County Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Canton
 Mercy Cancer Center at Mercy Medical Center
 Mitchell Haut, MD
Ph: 330-453-9993
  Chillicothe
 Adena Regional Medical Center
 Clinical Trials Office - Adena Regional Medical Center
Ph: 877-779-7585
  Cleveland
 MetroHealth Cancer Care Center at MetroHealth Medical Center
 Bruce Averbook, MD, FACS
Ph: 216-778-4795
  Clyde
 North Coast Cancer Care - Clyde
 Paul Schaefer, MD
Ph: 419-479-5605
  Columbus
 Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
 Ohio State University Cancer Clinical Trial Matching Service
Ph: 866-627-7616
 Email: osu@emergingmed.com
 CCOP - Columbus
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Doctors Hospital at Ohio Health
 Clinical Trials Office - Doctors Hospital at Ohio Health
Ph: 614-566-3275
 Grant Medical Center Cancer Care
 Clinical Trials Office - Grant Medical Center Cancer Care
Ph: 614-566-4475
 Mount Carmel Health - West Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Riverside Methodist Hospital Cancer Care
 Clinical Trials Office - Riverside Methodist Hospital Cancer Care
Ph: 614-566-4475
  Dayton
 CCOP - Dayton
 Howard Gross, MD
Ph: 937-832-1093
 David L. Rike Cancer Center at Miami Valley Hospital
 Clinical Trials Office - David L. Rike Cancer Center at Miami Valley Hospital
Ph: 937-208-2079
 Good Samaritan Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Grandview Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Samaritan North Cancer Care Center
 Howard Gross, MD
Ph: 937-832-1093
  Delaware
 Grady Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Elyria
 Hematology Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Findlay
 Blanchard Valley Medical Associates
 Howard Gross, MD
Ph: 937-832-1093
  Franklin
 Middletown Regional Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Greenville
 Wayne Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Kettering
 Charles F. Kettering Memorial Hospital
 Clinical Trials Office - Charles F. Kettering Memorial Hospital
Ph: 937-298-3399 ext. 57556
  Lancaster
 Fairfield Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Lima
 Lima Memorial Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Rita's Medical Center
 Clinical Trials Office - St. Rita's Medical Center
Ph: 419-226-9617
  Marietta
 Strecker Cancer Center at Marietta Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Maumee
 Northwest Ohio Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Luke's Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
  Newark
 Licking Memorial Cancer Care Program at Licking Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Norwalk
 Fisher-Titus Medical Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Oregon
 St. Charles Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic - Oregon
 Paul Schaefer, MD
Ph: 419-479-5605
  Sandusky
 North Coast Cancer Care, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Springfield
 Community Hospital of Springfield and Clark County
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Mercy Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Sylvania
 Flower Hospital Cancer Center
 Clinical Trials Office - Flower Hospital Cancer Center
Ph: 419-824-1842
  Tiffin
 Mercy Hospital of Tiffin
 Paul Schaefer, MD
Ph: 419-479-5605
  Toledo
 CCOP - Toledo Community Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Medical University of Ohio Cancer Center
 Clinical Trials Office - Medical University of Ohio Cancer Center
Ph: 419-383-6583
 St. Anne Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Vincent Mercy Medical Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic, Incorporated - Main Clinic
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Hospital
 Clinical Trials Office - Toledo Hospital
Ph: 419-824-1842
  Troy
 UVMC Cancer Care Center at Upper Valley Medical Center
 Clinical Trials Office - UVMC Cancer Care Center at Upper Valley Medical Center
Ph: 937-440-4842
  Wauseon
 Fulton County Health Center
 Clinical Trials Office - Fulton County Health Center
Ph: 419-330-2708
  Westerville
 Mount Carmel St. Ann's Cancer Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Wilmington
 Clinton Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Xenia
 Ruth G. McMillan Cancer Center at Greene Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Zanesville
 Genesis - Good Samaritan Hospital
 Clinical Trials Office - Genesis - Good Samaritan Hospital
Ph: 740-454-5232
Oklahoma
  Lawton
 Cleo Craig Cancer Research Clinic
 Nadim Nimeh, MD
Ph: 580-536-2121ext.113
  Oklahoma City
 Cancer Care Associates - Mercy Campus
 Howard Ozer, MD, PhD
Ph: 405-271-4022
 Oklahoma University Cancer Institute
 Howard Ozer, MD, PhD
Ph: 405-271-4022
Oregon
  Milwaukie
 Providence Milwaukie Hospital
 Janet Ruzich
Ph: 503-513-8300
  Portland
 Adventist Medical Center
 Janet Ruzich
Ph: 503-257-2500
 CCOP - Columbia River Oncology Program
 Janet Ruzich
Ph: 503-216-6260
 Providence Cancer Center at Providence Portland Medical Center
 Clinical Trials Office - Providence Cancer Center at Providence Portland Medical Center
Ph: 503-215-6412
 Providence St. Vincent Medical Center
 Clinical Trials Office - Providence St. Vincent Medical Center
Ph: 503-215-6412
Pennsylvania
  Bethlehem
 St. Luke's Cancer Network at St. Luke's Hospital
 Sanjiv Agarwala, MD
Ph: 610-954-2145
  Danville
 Geisinger Cancer Institute at Geisinger Health
 Clinical Trials Office - Geisinger Cancer Institute
Ph: 570-271-5251
  Darby
 Mercy Fitzgerald Hospital
 Clinical Trials Office - Mercy Fitzgerald Hospital
Ph: 610-237-4982
  Doylestown
 Doylestown Hospital Cancer Center
 Mitchell Alden, DO
Ph: 215-345-8444
  East Stroudsburg
 Dale and Frances Hughes Cancer Center at Pocono Medical Center
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Lancaster
 Lancaster General Hospital
 Randall Oyer
Ph: 717-544-5511
  Langhorne
 St. Mary Regional Cancer Center
 Clinical Trials Office - St. Mary Regional Cancer Center
Ph: 215-710-4585
  Media
 Riddle Memorial Hospital Cancer Center
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Philadelphia
 Abramson Cancer Center of the University of Pennsylvania
 Clinical Trials Office - Abramson Cancer Center of the University of Pennsylvania
Ph: 800-474-9892
 Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
 Clinical Trials Office - Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
Ph: 215-955-6084
  Phoenixville
 Cancer Center at Phoenixville Hospital
 Carl Sharer, DO
Ph: 610-983-1800
  Reading
 St. Joseph Medical Center
 Patrick Colarusso, DO
Ph: 610-378-2385
  Sayre
 Guthrie Cancer Center at Guthrie Clinic Sayre
 Clinical Trials Office - Guthrie Cancer Center at Guthrie Clinic Sayre
Ph: 800-836-0388
  Scranton
 Hematology and Oncology Associates of Northeastern Pennsylvania
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
 Martin Hyzinski, MD
Ph: 570-558-3020
 Mercy Hospital Cancer Center - Scranton
 Martin Hyzinski, MD
Ph: 570-558-3020
  Sellersville
 Grand View Hospital
 Anthony Magdalinski, III
Ph: 215-453-4000
  State College
 Geisinger Medical Group - Scenery Park
 Albert Bernath, MD
Ph: 570-214-9290
 Mount Nittany Medical Center
 Philip Lowry, MD
Ph: 978-343-5048
  Upland
 Associates in Hematology-Oncology, PC at Crozer Regional Cancer Center
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Wilkes-Barre
 Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
 Clinical Trials Office - Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
Ph: 570-271-5251
  York
 York Cancer Center at Apple Hill Medical Center
 Amir Tabatabai, MD
Ph: 717-741-9229
Rhode Island
  Cranston
 Hematology and Oncology Associates of Rhode Island
 Adam Olszewski
Ph: 401-943-4660
  Warwick
 Kent County Memorial Hospital
 Clinical Trials Office - Kent County Memorial Hospital
Ph: 401-737-7010 ext. 1864
South Carolina
  Anderson
 AnMed Cancer Center
 Clinical Trials Office - AnMed Cancer Center
Ph: 864-512-1000
  Beaufort
 Keyserling Cancer Center at Beaufort Memorial Hospital
 Majd Chahin
Ph: 877-532-6472
888-522-5585
  Spartanburg
 CCOP - Upstate Carolina
 Clinical Trials Office - CCOP - Upstate Carolina
Ph: 800-486-5941
 Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
 Clinical Trials Office - Gibbs Regional Cancer Center
Ph: 800-486-5941
South Dakota
  Aberdeen
 Oncology Services of Aberdeen
 Richard Conklin, MD
Ph: 605-622-5613
Tennessee
  Memphis
 University of Tennessee Cancer Institute - Memphis
 Clinical Trials Office - University of Tennessee Cancer Institute
Ph: 901-448-3303
Texas
  Amarillo
 Harrington Cancer Center
 Clinical Trials Officec - Harrington Cancer Center
Ph: 806-359-4673
 Email: ryokubaitis@harringtoncc.org
  Houston
 M. D. Anderson Cancer Center at University of Texas
 Clinical Trials Office - M. D. Anderson Cancer Center at the University of Texas
Ph: 713-792-3245
Vermont
  Berlin
 Mountainview Medical
 Marc Greenblatt, MD
Ph: 802-847-3827
  Burlington
 Fletcher Allen Health Care - University Health Center Campus
 Clinical Trials Office - Fletcher Allen Health Care
Ph: 802-656-8990
Virginia
  Charlottesville
 Martha Jefferson Hospital Cancer Care Center
 Robert Pritchard, MD
Ph: 434-982-8390
 University of Virginia Cancer Center
 Geoffrey Weiss, MD
Ph: 434-243-0066
  Fredericksburg
 Fredericksburg Oncology, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Hampton
 Virginia Oncology Associates - Hampton
 Paul Conkling, MD
Ph: 757-466-8683
  Richmond
 Veterans Affairs Medical Center - Richmond
 Clinical Trials Office - Veterans Affairs Medical Center - Richmond
Ph: 804-675-5646
Washington
  Auburn
 Auburn Regional Center for Cancer Care
 Lauren Colman, MD
Ph: 253-403-1677
  Centralia
 Providence Centralia Hospital
 Clinical Trials Office - Providence Centralia Hospital
Ph: 360-493-4300
  Federal Way
 St. Francis Hospital
 Lauren Colman, MD
Ph: 253-403-1677
  Olympia
 Providence St. Peter Hospital Regional Cancer Center
 Lauren Colman, MD
Ph: 253-403-1677
  Puyallup
 Good Samaritan Cancer Center
 Lauren Colman, MD
Ph: 253-403-1677
  Spokane
 Rockwood Clinic Cancer Treatment Center
 Clinical Trials Office - Rockwood Clinic Cancer Treatment Center
Ph: 509-838-2531 ext. 6880
  Tacoma
 Allenmore Hospital
 Lauren Colman, MD
Ph: 253-403-1677
 CCOP - Northwest
 Lauren Colman, MD
Ph: 253-403-1677
 Franciscan Cancer Center at St. Joseph Medical Center
 Clinical Trials Office - Franciscan Cancer Center
Ph: 253-426-6914
 St. Clare Hospital
 Lauren Colman, MD
Ph: 253-403-1677
  Vancouver
 Southwest Washington Medical Center Cancer Center
 Janet Ruzich
Ph: 360-514-2174
  Walla Walla
 St. Mary Regional Cancer Center at St. Mary Medical Center
 Robert Quackenbu
Ph: 509-522-5700
West Virginia
  Charleston
 West Virginia University Health Sciences Center - Charleston
 Steven Jubelirer, MD
Ph: 304-388-8380
  Huntington
 Edwards Comprehensive Cancer Center at Cabell Huntington Hospital
 Oncology Research Supervisor
Ph: 304-399-6617
  Princeton
 Princeton Community Hospital
 Rowena Gonzales-Chambers, MD
Ph: 304-425-1453
Wisconsin
  Antigo
 Langlade Memorial Hospital
 Christopher Peterson
Ph: 715-623-2331
  Appleton
 Fox Valley Hematology and Oncology - East Grant Street
 Timothy Goggins
Ph: 920-749-1171
  Chippewa Falls
 Marshfield Clinic - Chippewa Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Eau Claire
 Marshfield Clinic Cancer Care at Regional Cancer Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Elkhorn
 Vince Lombardi Cancer Center at Aurora Lakeland Medical Center - Elkhorn
 Rossana Madamba
Ph: 262-741-2671
800-252-2990
  Glendale
 Oncology Alliance, SC - Milwaukee - East
 Clinical Trials Office - Oncology Alliance, SC - Milwaukee - East
Ph: 414-906-4480
  Green Bay
 Green Bay Oncology, Limited at St. Mary's Hospital
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
 Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
 St. Mary's Hospital Medical Center - Green Bay
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
 St. Vincent Hospital Regional Cancer Center
 Clinical Trials Office - St. Vincent Hospital Regional Cancer Center
Ph: 920-433-8889
 Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
 Clinical Trials Office - Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
Ph: 414-649-5717
  La Crosse
 Franciscan Skemp Healthcare - La Crosse Campus
 Haleem Rasool
Ph: 608-782-9760
 Gundersen Lutheran Center for Cancer and Blood
 Clinical Trials Office - Gundersen Lutheran Cancer Center
Ph: 608-775-2385
 Email: cancerctr@gundluth.org
  Manitowoc
 Holy Family Memorial Medical Center Cancer Care Center
 Clinical Trials Office - Holy Family Memorial Medical Center Cancer Care Center
Ph: 920-320-2749
  Marinette
 Bay Area Cancer Care Center at Bay Area Medical Center
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
 Vince Lombardi Cancer Clinic - Marinette
 Dhimant Patel, MD
Ph: 920-288-4180
  Marshfield
 Marshfield Clinic - Marshfield Center
 Clinical Trials Office - Marshfield Clinic - Marshfield Center
Ph: 800-782-1581 ext. 94457
 Saint Joseph's Hospital
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Milwaukee
 Medical Consultants, Limited
 Jonathan Treisman, MD
Ph: 414-385-3086
  Minocqua
 Marshfield Clinic - Lakeland Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Oconomowoc
 Regional Cancer Center at Oconomowoc Memorial Hospital
 Clinical Trials Office - Regional Cancer Center at Oconomowoc Memorial Hospital
Ph: 262-928-7878
  Oconto Falls
 Green Bay Oncology, Limited - Oconto Falls
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
  Oshkosh
 Vince Lombardi Cancer Clinic - Oshkosh
 Zahid Dar
Ph: 920-303-8700
  Rhinelander
 Ministry Medical Group at Saint Mary's Hospital
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Rice Lake
 Marshfield Clinic - Indianhead Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Sheboygan
 Vince Lombardi Cancer Clinic - Sheboygan
 Clinical Trials Office - Vince Lombardi Cancer Clinic - Sheboygan
Ph: 414-649-7200
  Stevens Point
 Saint Michael's Hospital Cancer Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Sturgeon Bay
 Green Bay Oncology, Limited - Sturgeon Bay
 Thomas Saphner, MD, FACP
Ph: 920-884-3135
  Two Rivers
 Vince Lombardi Cancer Clinic - Two Rivers
 Andrew Yetter
Ph: 920-793-6000
  Waukesha
 Waukesha Memorial Hospital Regional Cancer Center
 Clinical Trials Office - Waukesha Memorial Hospital Regional Cancer Center
Ph: 262-928-7632
  Wausau
 Marshfield Clinic - Wausau Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
 University of Wisconcin Cancer Center at Aspirus Wausau Hospital
 Clinical Trials Office - University of Wisconsin Cancer Center
Ph: 608-262-5223
  Weston
 Marshfield Clinic - Weston Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
  Wisconsin Rapids
 Marshfield Clinic - Wisconsin Rapids Center
 Mohammad Khan, MD, FACP
Ph: 715-387-5426
Wyoming
  Sheridan
 Welch Cancer Center at Sheridan Memorial Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290

Related Information

Featured trial article

Registry Information
Official Title A Phase III Trial of Irinotecan / 5-FU / Leucovorin or Oxaliplatin / 5-FU/ Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum
Trial Start Date 2005-11-30
Trial Completion Date 2008-06-02 (estimated)
Registered in ClinicalTrials.gov NCT00265850
Date Submitted to PDQ 2005-11-04
Information Last Verified 2009-11-20
NCI Grant/Contract Number CA37447

Note: The purpose of most clinical trials listed in this database is to test new cancer treatments, or new methods of diagnosing, screening, or preventing cancer. Because all potentially harmful side effects are not known before a trial is conducted, dose and schedule modifications may be required for participants if they develop side effects from the treatment or test. The therapy or test described in this clinical trial is intended for use by clinical oncologists in carefully structured settings, and may not prove to be more effective than standard treatment. A responsible investigator associated with this clinical trial should be consulted before using this protocol.

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