National Cancer Institute National Cancer Institute
U.S. National Institutes of Health National Cancer Institute
In English | En español
NCI Home Cancer Topics Clinical Trials Cancer Statistics Research & Funding News About NCI
Clinical Trials (PDQ®)
Patient VersionHealth Professional Version
Last Modified: 11/21/2009     First Published: 12/1/1998  
Page Options
Print This Page  Print This Page
E-Mail This Document  E-Mail This Document
Clinical Trial Questions?
Get Help:

1-800-4-CANCER or

LiveHelp online chat

Quick Links
Help Using the NCI Clinical Trials Search Form

Educational Materials About Clinical Trials

About NCI's Cancer Clinical Trials Registry

Dictionary of Cancer Terms

NCI Drug Dictionary
Phase III Randomized Adjuvant Study of High-Dose Interferon alfa-2b Therapy in Patients With Stage II or III Melanoma

Alternate Title
Basic Trial Information
Objectives
Entry Criteria
Expected Enrollment
Outcomes
Outline
Trial Contact Information
Registry Information

Alternate Title

High-Dose Interferon alfa in Treating Patients With Stage II or Stage III Melanoma

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentActive18 and overNCIECOG-1697
SWOG-E1697, CALGB-500103, CAN-NCIC-ME10, COG-E1697, E1697, NCT00003641, ME10

Special Category: CTSU trial

Objectives

  1. Compare the effect of high-dose interferon alfa-2b treatment on the relapse-free survival of patients with stage II or III resected malignant melanoma.
  2. Compare the effect of this treatment regimen on overall survival of these patients.
  3. Assess the toxicity of this treatment in these patients.
  4. Compare the effect of treatment on quality-adjusted survival.

Entry Criteria

Disease Characteristics:

  • Histologically confirmed primary melanoma of cutaneous origin
    • Stage II (T3 N0 M0 1.5-4.0 mm Breslow depth)
      • Clinically negative regional lymph node pathologic status unknown

        OR

      • Histologically negative regional lymph nodes
    • Stage III (T4 N0 M0)
      • Greater than 4.0 mm Breslow depth

      OR

    • Stage III (T1-4 N1)
      • One lymph node positive microscopically

  • Patients must meet at least 1 of the following criteria:
    • T2b N0 - primary melanoma 1.01-2.0 mm with ulceration, node negative
    • T3a-b N0 - primary melanoma 2.01-4.0 mm with and without ulceration, node negative
    • T4a-b N0 - primary melanoma > 4.0 mm with or without ulceration, node negative
    • T1-a N1a-2a (microscopic) - primary melanoma of any thickness with microscopically positive lymph node (any number)

  • Patients with a positive sentinel node should undergo complete lymphadenectomy of the nodal basin prior to study

  • Must complete all primary therapy (wide excision with or without lymphadenectomy) and be randomized in this study within 84 days of wide excision

  • Must have undergone an adequate wide excision of the primary lesion

  • No clinical, radiological/laboratory, or pathological evidence of incompletely resected melanoma or any distant metastatic disease

  • No clinically palpable lymphadenopathy

Prior/Concurrent Therapy:

Biologic therapy:

  • No prior immunotherapy including tumor vaccines, interferon, interleukins, levamisole, or other biologic response modifiers for melanoma

Chemotherapy:

  • No prior or concurrent chemotherapy

Endocrine therapy:

  • No concurrent systemic corticosteroids including oral steroids (i.e., prednisone, dexamethasone), topical steroid creams or ointments, or any steroid-containing inhalers

Radiotherapy:

  • No prior or concurrent radiotherapy

Surgery:

  • See Disease Characteristics

Other:

  • No other concurrent immunosuppressive medications

Patient Characteristics:

Age:

  • 18 and over

Performance status:

  • ECOG 0-1

Life expectancy:

  • Not specified

Hematopoietic:

  • WBC at least 3,000/mm3
  • Platelet count at least 125,000/mm3
  • Hematocrit at least 30%

Hepatic:

  • Bilirubin no greater than 2 times upper limit of normal (ULN)
  • AST, LDH, and alkaline phosphatase no greater than 2 times ULN
  • If lactate dehydrogenase or alkaline phosphatase is above normal, a contrast-enhanced CT scan or MRI of the liver is required to document the absence of tumor

Renal:

  • BUN no greater than 33 mg/dL

    OR

  • Creatinine no greater than 1.8 mg/dL

Cardiovascular:

  • No history of active ischemic heart disease
  • No cerebrovascular disease
  • No congestive heart failure (New York Heart Association class III or IV heart disease)

Other:

  • No other history of invasive melanoma
  • No autoimmune disorders or conditions of immunosuppression
  • No other concurrent or prior malignancies within the past 5 years except:
    • Cancer in situ
    • Lobular carcinoma in situ of the breast
    • Carcinoma in situ of the cervix
    • Atypical melanocytic hyperplasia or Clark 1 melanoma in situ
    • Basal or squamous cell skin cancer
  • No evidence of organic brain syndrome or significant impairment of basal cognitive function or any psychiatric disorder that would preclude study participation
  • No other significant medical or surgical condition, or any medication or treatment regimens, that would interfere with study participation
  • Not pregnant or nursing
  • Negative pregnancy test
  • Fertile patients must use effective contraception during and for 6 months after study

Expected Enrollment

1420

A total of 1,420 patients will be accrued for this study over 5 years.

Outcomes

Primary Outcome(s)

Disease control interval
Interferon alfa-2b toxicity

Outline

This is a randomized study. Patients are stratified by pathologic lymph node status (known vs unknown by sentinel lymph node procedure vs by elective lymph node dissection vs by no lymphadenectomy), Breslow depth (< 1.0 mm [lymph node positive patients only] vs 1.01-2.0 mm vs 2.01-4.0 mm vs > 4.0 mm), ulceration of the primary lesion (yes vs no vs unknown), and disease stage (lymph node positive [N1a, N2a microscopic] vs lymph node negative [N0]). Patients are randomized into one of two treatment arms.

  • Arm I: Patients undergo observation for 4 weeks.

  • Arm II: Patients receive high-dose interferon alfa-2b IV over 20 minutes daily for 5 consecutive days. Treatment repeats weekly for 4 weeks in the absence of unacceptable toxicity.

Quality of life is assessed before treatment, at day 22, every 3 months for 2 years, and then every 6 months for 3 years.

Patients are followed every 3 months for 2 years, every 6 months for 3 years, and then annually thereafter.

Trial Contact Information

Trial Lead Organizations

Eastern Cooperative Oncology Group

Sanjiv Agarwala, MD, Protocol chair
Ph: 610-954-2145
John Kirkwood, MD, Protocol co-chair
Ph: 412-623-7707
Email: kirkwoodjm@upmc.edu

Southwest Oncology Group

Lawrence Flaherty, MD, Protocol chair
Ph: 313-576-8715; 800-527-6266
Email: flaherty@karmanos.org

Cancer and Leukemia Group B

William Carson, MD, Protocol chair
Ph: 614-292-5819
Email: william.carson@osumc.edu

NCIC-Clinical Trials Group

Michael Smylie, MD, MB, ChB, Protocol chair
Ph: 780-432-8757
Email: michaels@cancerboard.ab.ca

Children's Oncology Group

Alberto Pappo, MD, Principal investigator
Ph: 832-822-4200

Trial Sites

U.S.A.
Alabama
  Birmingham
 UAB Comprehensive Cancer Center
 Clinical Trials Office - UAB Comprehensive Cancer Center
Ph: 205-934-0309
  Mobile
 University of South Alabama Mitchell Cancer Institute
 Adam Riker
Ph: 251-460-6993
Arizona
  Phoenix
 Phoenix Children's Hospital
 Jessica Boklan
Ph: 602-546-0920
  Scottsdale
 Mayo Clinic Scottsdale
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Tucson
 Arizona Cancer Center at University of Arizona Health Sciences Center
 Clinical Trials Office - Arizona Cancer Center at University of Arizona Health Sciences Center
Ph: 520-626-9008
Arkansas
  Ft. Smith
 Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
 John Wells, MD
Ph: 479-484-4700
  Little Rock
 Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
 Clinical Trial Office - Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
Ph: 501-686-8274
California
  Berkeley
 Alta Bates Summit Comprehensive Cancer Center
 Clinical Trials Office - Alta Bates Summit Comprehensive Cancer Center
Ph: 510-204-3428
  Burbank
 Providence Saint Joseph Medical Center - Burbank
 Clinical Trials Office - Providence Saint Joseph Medical Center - Burbank
Ph: 818-847-3220
  Burlingame
 Peninsula Medical Center
 David Irwin, MD
Ph: 510-204-1591
  Downey
 Southern California Permanente Medical Group
 Robert Cooper
Ph: 323-783-5307
 Robert Cooper
Ph: 562-461-3000
  Fremont
 Kaiser Permanente - Fremont
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Greenbrae
 Marin Cancer Institute at Marin General Hospital
 David Irwin, MD
Ph: 510-204-1591
 Sutter Health - Western Division Cancer Research Group
 David Irwin, MD
Ph: 510-204-1591
  Hayward
 Kaiser Permanente Medical Center - Hayward
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Loma Linda
 Loma Linda University Cancer Institute at Loma Linda University Medical Center
 Clinical Trials Office - Loma Linda University Cancer Institute
Ph: 909-558-3375
  Oakland
 Kaiser Permanente Medical Center - Oakland
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Palo Alto
 Veterans Affairs Medical Center - Palo Alto
 Harlan Pinto, MD
Ph: 650-725-9057
  Redwood City
 Kaiser Permanente Medical Center - Redwood City
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Richmond
 Kaiser Permanente Medical Center - Richmond
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Roseville
 Kaiser Permanente Medical Center - Roseville
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Sutter Cancer Center at Roseville Medical Center
 Clinical Trials Office - Sutter Cancer Center
Ph: 916-454-6595
  Sacramento
 Kaiser Permanente Medical Center - Sacramento
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 South Sacramento Kaiser-Permanente Medical Center
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Sutter Cancer Center
 Clinical Trial Office - Sutter Cancer Center
Ph: 916-454-6595
 University of California Davis Cancer Center
 Clinical Trials Office - University of California Davis Cancer Center
Ph: 916-734-3089
  San Diego
 Kaiser Permanente Medical Office -Vandever Medical Office
 Han Koh
Ph: 619-528-2596
 Naval Medical Center - San Diego
 Preston Gable, MD, FACP
Ph: 619-532-7319
  San Francisco
 California Pacific Medical Center - California Campus
 David Irwin, MD
Ph: 510-204-1591
 Kaiser Permanente Medical Center - San Francisco Geary Campus
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 UCSF Helen Diller Family Comprehensive Cancer Center
 Clinical Trials Office - UCSF Helen Diller Family Comprehensive Cancer Center
Ph: 877-827-3222
  San Jose
 Kaiser Permanente Medical Center - Santa Teresa
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  San Rafael
 Kaiser Foundation Hospital - San Rafael
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Santa Clara
 Kaiser Permanente Medical Center - Santa Clara Kiely Campus
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Santa Rosa
 Kaiser Permanente Medical Center - Santa Rosa
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  South San Francisco
 Kaiser Permanente Medical Center - South San Francisco
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Stanford
 Stanford Cancer Center
 Clinical Trials Office - Stanford Cancer Center
Ph: 650-498-7061
 Email: cctoffice@stanford.edu
  Stockton
 Kaiser Permanente Medical Facility - Stockton
 Louis Fehrenbacher, MD
Ph: 707-651-2577
  Vallejo
 Kaiser Permanente Medical Center - Vallejo
 Louis Fehrenbacher, MD
Ph: 707-651-2577
 Sutter Solano Medical Center
 David Irwin, MD
Ph: 510-204-1591
  Walnut Creek
 Kaiser Permanente Medical Center - Walnut Creek
 Louis Fehrenbacher, MD
Ph: 707-651-2577
Colorado
  Aurora
 Aurora Presbyterian Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 University of Colorado Cancer Center at UC Health Sciences Center
 Clinical Trials Office - University of Colorado Cancer Center
Ph: 720-848-0650
  Boulder
 Boulder Community Hospital
 Clinical Trials Office - Boulder Community Hospital
Ph: 303-938-5253
  Colorado Springs
 Penrose Cancer Center at Penrose Hospital
 Clinical Trials Office - Penrose Cancer Center
Ph: 719-776-5275
  Denver
 CCOP - Colorado Cancer Research Program
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Porter Adventist Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Presbyterian - St. Luke's Medical Center
 Clinical Trials Office - Presbyterian - St. Luke's Medical Center
Ph: 303-839-6000
 Rose Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Anthony Central Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Joseph Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Edwards
 Shaw Regional Cancer Center
 Anthony Elias, MD
Ph: 720-848-1622
  Englewood
 Swedish Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Glenwood Springs
 Valley View Hospital Cancer Center
 Anthony Elias, MD
Ph: 720-848-1622
  Grand Junction
 St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Greeley
 North Colorado Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Lone Tree
 Sky Ridge Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Longmont
 Hope Cancer Care Center at Longmont United Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Loveland
 McKee Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Montrose
 Montrose Memorial Hospital Cancer Center
 Clinical Trials Office - Montrose Memorial Hospital Cancer Center
Ph: 670-240-7267
  Pueblo
 St. Mary - Corwin Regional Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Thornton
 North Suburban Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Wheat Ridge
 Exempla Lutheran Medical Center
 Clinical Trials Office - Exempla Lutheran Medical Center
Ph: 303-403-3605
Connecticut
  New Haven
 Yale Cancer Center
 Clinical Trials Office - Yale Cancer Center
Ph: 203-785-5702
  Norwich
 Eastern Connecticut Hematology and Oncology Associates
 Dennis Slater, MD
Ph: 860-886-8362
  Stamford
 Carl and Dorothy Bennett Cancer Center at Stamford Hospital
 Clinical Trials Office - Carl and Dorothy Bennett Cancer Center
Ph: 203-323-8944
Delaware
  Lewes
 Tunnell Cancer Center at Beebe Medical Center
 Clinical Trials Office - Tunnell Cancer Center
Ph: 302-645-3171
  Newark
 CCOP - Christiana Care Health Services
 Clinical Trial Office - CCOP - Christiana Care Health Services
Ph: 302-733-6227
Florida
  Fort Lauderdale
 Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
 Clinical Trials Office - Michael and Dianne Bienes Comprehensive Cancer Center
Ph: 954-776-3239
  Jacksonville
 Mayo Clinic - Jacksonville
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Jupiter
 Ella Milbank Foshay Cancer Center at Jupiter Medical Center
 Clinical Trials Office - Ella Milbank Foshay Cancer Center
Ph: 561-745-5768
  Lakeland
 Lakeland Regional Cancer Center at Lakeland Regional Medical Center
 Douglas Reintgen, MD
Ph: 863-603-6565
  Miami
 University of Miami Sylvester Comprehensive Cancer Center - Miami
 University of Miami Sylvester Comprehensive Cancer Center Clinical Trial Matching Service
Ph: 866-574-5124
 Email: Sylvester@emergingmed.com
  Miami Beach
 CCOP - Mount Sinai Medical Center
 Jose Lutzky, MD
Ph: 305-535-3305
  Pensacola
 Sacred Heart Cancer Center at Sacred Heart Hospital
 Clinical Trials Office - Sacred Heart Cancer Center
Ph: 850-416-4611
 West Florida Cancer Institute at West Florida Hospital - Pensacola
 Ranjith Dissanayake
Ph: 850-474-8382
  Saint Petersburg
 All Children's Hospital
 Gregory Hale
Ph: 727-898-7451
800-456-4543
  Sarasota
 Florida Cancer Specialists - Sarasota Downtown
 Clinical Trials Office - Florida Cancer Specialists - Sarasota Downtown
Ph: 941-957-1000 ext. 213
  St. Petersburg
 All Children's Hospital
 Jerry Barbosa
Ph: 727-767-4176
  West Palm Beach
 Kaplan Cancer Center at St. Mary's Medical Center
 Contact Person
Ph: 561-881-2815
Georgia
  Altanta
 Winship Cancer Institute of Emory University
 David Lawson, MD
Ph: 404-778-4348
  Atlanta
 CCOP - Atlanta Regional
 Thomas Seay, MD, PhD
Ph: 404-851-2340
 Northside Hospital Cancer Center
 Clinical Trials Office - Northside Hospital Cancer Center
Ph: 404-303-3355
 Piedmont Hospital
 Thomas Seay, MD, PhD
Ph: 404-851-2340
 Saint Joseph's Hospital of Atlanta
 Clinical Trials Office - Saint Joseph's Hospital of Atlanta
Ph: 404-851-7115
  Austell
 WellStar Cobb Hospital
 Clinical Trials Office - WellStar Cobb Hospital
Ph: 770-793-5980
  Columbus
 John B. Amos Cancer Center
 Clinical Trials Office - John B. Amos Cancer Center
Ph: 706-660-6404
  Decatur
 Charles B. Eberhart Cancer Center at DeKalb Medical Center
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Gainesville
 Northeast Georgia Medical Center
 Richard LoCicero, MD
Ph: 770-297-5700
  Lawrenceville
 Gwinnett Medical Center
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Marietta
 Kennestone Cancer Center at Wellstar Kennestone Hospital
 Clinical Trials Office - Kennestone Cancer Center
Ph: 770-793-5980
  Riverdale
 Southern Regional Medical Center
 Clinical Trials Office - Southern Regional Medical Center
Ph: 770-991-8611
  Rome
 Harbin Clinic Cancer Center - Medical Oncology
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Savannah
 Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
 Howard Zaren, MD, FACS
Ph: 312-864-5204
Illinois
  Berwyn
 Hematology Oncology Associates of Illinois - Berwyn
 Timothy Kuzel, MD
Ph: 312-695-6180
  Chicago
 Hematology and Oncology Associates
 Clinical Trails Office - Hematology and Oncology Associates
Ph: 312-695-1301
 Robert H. Lurie Comprehensive Cancer Center at Northwestern University
 Clinical Trials Office - Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Ph: 312-695-1301
 Email: cancer@northwestern.edu
 Saint Joseph Hospital
 Timothy Kuzel, MD
Ph: 312-695-6180
  Decatur
 Decatur Memorial Hospital Cancer Care Institute
 Clinical Trials Office - Decatur Memorial Hospital Cancer Care Institute
Ph: 217-876-6601
  Evanston
 Evanston Hospital
 Clinical Trials Office - Evanston Hospital
Ph: 847-570-1381
  Harvey
 Ingalls Cancer Care Center at Ingalls Memorial Hospital
 Clinical Trials Office - Ingalls Cancer Care Center at Ingalls Memorial Hospital
Ph: 708-915-6747
  Hinsdale
 Hinsdale Hematology Oncology Associates
 Elyse Schneiderman, MD
Ph: 630-654-1790
  Joliet
 Midwest Center for Hematology/Oncology
 Timothy Kuzel, MD
Ph: 312-695-6180
  Libertyville
 North Shore Oncology and Hematology Associates, Limited - Libertyville
 Timothy Kuzel, MD
Ph: 312-695-6180
  Naperville
 La Grange Oncology Associates - Geneva
 Timothy Kuzel, MD
Ph: 312-695-6180
  Niles
 Cancer Care and Hematology Specialists of Chicagoland - Niles
 Timothy Kuzel, MD
Ph: 312-695-6180
  Rockford
 Swedish-American Regional Cancer Center
 Clinical Trials Office - Swedish-American Regional Cancer Center
Ph: 815-489-4413
  Skokie
 Hematology Oncology Associates - Skokie
 Timothy Kuzel, MD
Ph: 312-695-6180
Indiana
  Beech Grove
 St. Francis Hospital and Health Centers - Beech Grove Campus
 Howard Gross, MD
Ph: 937-832-1093
  Elkhart
 Elkhart General Hospital
 Bilal Ansari, MD
Ph: 269-983-8260
  Indianapolis
 Indiana University Melvin and Bren Simon Cancer Center
 Clinical Trials Office - Indiana University Cancer Center
Ph: 317-274-2552
 William N. Wishard Memorial Hospital
 Theodore Logan, MD
Ph: 317-278-7576
  Kokomo
 Howard Community Hospital
 Bilal Ansari, MD
Ph: 269-983-8260
  La Porte
 Center for Cancer Therapy at LaPorte Hospital and Health Services
 Bilal Ansari, MD
Ph: 269-983-8260
  Richmond
 Reid Hospital & Health Care Services
 Howard Gross, MD
Ph: 937-832-1093
  South Bend
 CCOP - Northern Indiana CR Consortium
 Bilal Ansari, MD
Ph: 269-983-8260
 Memorial Hospital of South Bend
 Clinical Trials Office - Memorial Hospital of South Bend
Ph: 800-284-7370
 Saint Joseph Regional Medical Center
 Bilal Ansari, MD
Ph: 269-983-8260
 South Bend Clinic
 Bilal Ansari, MD
Ph: 269-983-8260
Iowa
  Ames
 McFarland Clinic, PC
 Clinical Trials Office - McFarland Clinic, PC
Ph: 515-239-2621
  Cedar Rapids
 Cedar Rapids Oncology Associates
 Clinical Trials Office - Cedar Rapids Oncology Associates
Ph: 319-363-2690
 Mercy Regional Cancer Center at Mercy Medical Center
 Martin Wiesenfeld, MD
Ph: 319-363-8303
  Clive
 Medical Oncology and Hematology Associates - West Des Moines
 Robert Behrens
Ph: 515-875-9713
  Davenport
 Genesis Medical Center - West Campus
 George Kovach, MD
Ph: 563-421-1960
 Genesis Regional Cancer Center at Genesis Medical Center
 George Kovach, MD
Ph: 563-421-1960
  Des Moines
 CCOP - Iowa Oncology Research Association
 Robert Behrens
Ph: 515-244-7586
888-244-6061
 John Stoddard Cancer Center at Iowa Lutheran Hospital
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Lutheran Hospital
Ph: 515-241-8704
 John Stoddard Cancer Center at Iowa Methodist Medical Center
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Methodist Medical Center
Ph: 515-241-6727
 Medical Oncology and Hematology Associates at John Stoddard Cancer Center
 Robert Behrens
Ph: 515-282-2921
 Medical Oncology and Hematology Associates at Mercy Cancer Center
 Robert Behrens
Ph: 515-643-8740
 Mercy Cancer Center at Mercy Medical Center - Des Moines
 Robert Behrens
Ph: 515-643-8206
888-221-4849
  Dubuque
 Wendt Regional Cancer Center at Finley Hospital
 James Baer, MD
Ph: 563-589-2468
  Ottumwa
 McCreery Cancer Center at Ottumwa Regional
 Robert Behrens
Ph: 641-684-2946
  Sioux City
 Mercy Medical Center - Sioux City
 Donald Wender, MD, PhD
Ph: 712-252-0088
 Siouxland Hematology-Oncology Associates, LLP
 Donald Wender, MD, PhD
Ph: 712-252-0088
 St. Luke's Regional Medical Center
 Donald Wender, MD, PhD
Ph: 712-252-0088
  Waterloo
 Covenant Cancer Treatment Center
 Clinical Trials Office - Covenant Cancer Treatment Center
Ph: 319-272-2070
Kansas
  Chanute
 Cancer Center of Kansas, PA - Chanute
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Dodge City
 Cancer Center of Kansas, PA - Dodge City
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  El Dorado
 Cancer Center of Kansas, PA - El Dorado
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Fort Scott
 Cancer Center of Kansas - Fort Scott
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Independence
 Cancer Center of Kansas-Independence
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Kingman
 Cancer Center of Kansas, PA - Kingman
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Lawrence
 Lawrence Memorial Hospital
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Liberal
 Southwest Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Newton
 Cancer Center of Kansas, PA - Newton
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Parsons
 Cancer Center of Kansas, PA - Parsons
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Pratt
 Cancer Center of Kansas, PA - Pratt
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Salina
 Cancer Center of Kansas, PA - Salina
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Tammy Walker Cancer Center at Salina Regional Health Center
 William Cathcart-Rake, MD
Ph: 785-452-4860
  Topeka
 Cotton-O'Neil Cancer Center
 Clinical Trials Office - Cotton-O'Neil Cancer Center
Ph: 785-270-4963
  Wellington
 Cancer Center of Kansas, PA - Wellington
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Wichita
 Associates in Womens Health, PA - North Review
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Medical Arts Tower
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 CCOP - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Via Christi Cancer Center at Via Christi Regional Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Winfield
 Cancer Center of Kansas, PA - Winfield
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
Kentucky
  Ashland
 Cancer Care at Our Lady of Bellefonte Hospital
 Clinical Trials Office - Cancer Care at Our Lady of Bellefonte Hospital
Ph: 606-833-3253
  Madisonville
 Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County
 Clinical Trials Office - Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County
Ph: 800-733-2312
Louisiana
  Monroe
 Louisiana State University Health Sciences Center - Monroe
 Glenn Mills, MD
Ph: 318-813-1440
  Shreveport
 Feist-Weiller Cancer Center at Louisiana State University Health Sciences
 Clinical Trials Office - Feist-Weiller Cancer Center at Louisiana State University Health Sciences
Ph: 318-813-1412
Maine
  Scarborough
 Maine Center for Cancer Medicine and Blood Disorders - Scarborough
 Frederick Aronson, MD
Ph: 207-885-7600
Maryland
  Annapolis
 DeCesaris Cancer Institute at Anne Arundel Medical Center
 Curtis Harris
Ph: 443-481-5800
  Baltimore
 Greater Baltimore Medical Center Cancer Center
 Clinical Trials Office - Greater Baltimore Medical Center Cancer Center
Ph: 443-849-3706
  Elkton MD
 Union Hospital Cancer Program at Union Hospital
 Stephen Grubbs, MD
Ph: 302-366-1200
Massachusetts
  Boston
 Tufts-NEMC Cancer Center
 Gary Strauss
Ph: 617-636-6100
Michigan
  Adrian
 Hickman Cancer Center at Bixby Medical Center
 Clinical Trials Office - Hickman Cancer Center at Bixby Medical Center
Ph: 517-265-0116
  Ann Arbor
 CCOP - Michigan Cancer Research Consortium
 Philip Stella, MD
Ph: 734-712-1000
 Saint Joseph Mercy Cancer Center
 Philip Stella, MD
Ph: 734-712-1000
  Dearborn
 Oakwood Cancer Center at Oakwood Hospital and Medical Center
 Clinical Trials Office - Oakwood Cancer Center at Oakwood Hospital and Medical Center
Ph: 313-593-8090
  Detroit
 Barbara Ann Karmanos Cancer Institute
 Clinical Trials Office - Barbara Ann Karmanos Cancer Institute
Ph: 313-576-9363
  Escanaba
 Green Bay Oncology, Limited - Escanaba
 Gerald Bayer, MD
Ph: 920-432-6049
  Flint
 Genesys Hurley Cancer Institute
 Clinical Trials Office - Genesys Hurley Cancer Institute
Ph: 810-762-8057
 Hurley Medical Center
 Clinical Trials Office - Hurley Medical Center
Ph: 810-762-8057
  Grosse Pointe Woods
 Van Elslander Cancer Center at St. John Hospital and Medical Center
 Clincial Trials Office - Van Elslander Cancer Center at St. John Hospital and Medical Center
Ph: 313-343-3166
  Iron Mountain
 Dickinson County Healthcare System
 Gerald Bayer, MD
Ph: 920-432-6049
  Jackson
 Foote Memorial Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Kalamazoo
 Borgess Medical Center
 Raymond Lord, MD
Ph: 269-373-7458
 Bronson Methodist Hospital
 Raymond Lord, MD
Ph: 269-373-7458
 West Michigan Cancer Center
 Clinical Trials Office - West Michigan Cancer Center
Ph: 269-373-7458
  Lambertville
 Haematology-Oncology Associates of Ohio and Michigan, PC
 Paul Schaefer, MD
Ph: 419-479-5605
  Lansing
 Sparrow Regional Cancer Center
 Clinical Trials Office - Sparrow Regional Cancer Center
Ph: 517-364-2890
  Livonia
 St. Mary Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Monroe
 Community Cancer Center of Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
 Mercy Memorial Hospital - Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
  Pontiac
 St. Joseph Mercy Oakland
 Philip Stella, MD
Ph: 734-712-1000
  Port Huron
 Mercy Regional Cancer Center at Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Royal Oak
 William Beaumont Hospital - Royal Oak Campus
 Clinical Trials Office - William Beaumont Hospital - Royal Oak Campus
Ph: 248-551-7695
  Saginaw
 Seton Cancer Institute at Saint Mary's - Saginaw
 Clinical Trials Office - Seton Cancer Institute - Saginaw
Ph: 989-776-8411
  St. Joseph
 Lakeland Regional Cancer Care Center - St. Joseph
 Bilal Ansari, MD
Ph: 269-983-8260
  Warren
 St. John Macomb Hospital
 Philip Stella, MD
Ph: 734-712-1000
Minnesota
  Alexandria
 Donald Jurgens
Ph: 320-229-4907
  Bemidji
 MeritCare Bemidji
 Preston Steen, MD
Ph: 701-234-2397
  Burnsville
 Fairview Ridges Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Coon Rapids
 Mercy and Unity Cancer Center at Mercy Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Duluth
 CCOP - Duluth
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 Duluth Clinic Cancer Center - Duluth
 Clinical Trials Office - Duluth Clinic Cancer Center - Duluth
Ph: 218-786-3308
 Miller - Dwan Medical Center
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 St. Luke's Hospital Cancer Care Center
 Tanya Repka, MD, FACP
Ph: 218-726-3081
  Edina
 Fairview Southdale Hospital
 Clinical Trials Office - Fairview Southdale Hospital
Ph: 612-625-3650
  Fridley
 Mercy and Unity Cancer Center at Unity Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Hutchinson
 Hutchinson Area Health Care
 Daniel Anderson
Ph: 320-234-5000
800-454-3903
  Maplewood
 HealthEast Cancer Care at St. John's Hospital
 Daniel Anderson
Ph: 651-232-7970
 Minnesota Oncology Hematology, PA - Maplewood
 Patrick Flynn, MD
Ph: 612-863-8585
  Minneapolis
 Hennepin County Medical Center - Minneapolis
 Clinical Trials Office - Hennepin County Medical Center - Minneapolis
Ph: 612-873-5911
 Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
 Clinical Trials Office - Virginia Piper Cancer Institute
Ph: 612-863-5654
  Robbinsdale
 Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
 Clinical Trials Office - Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
Ph: 763-520-1893
  Rochester
 Mayo Clinic Cancer Center
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Saint Cloud
 CentraCare Clinic - River Campus
 Donald Jurgens
Ph: 320-229-4907
 Coborn Cancer Center
 Donald Jurgens
Ph: 320-229-4907
  Saint Louis Park
 CCOP - Metro-Minnesota
 Patrick Flynn, MD
Ph: 612-863-8585
 Park Nicollet Cancer Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Saint Paul
 United Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Shakopee
 St. Francis Cancer Center at St. Francis Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  St. Paul
 Regions Hospital Cancer Care Center
 Clinical Trials Office - Regions Hospital Cancer Care Center
Ph: 651-254-1517
  Waconia
 Ridgeview Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Woodbury
 Minnesota Oncology Hematology, PA - Woodbury
 Patrick Flynn, MD
Ph: 612-863-8585
Mississippi
  Jackson
 University of Mississippi Cancer Clinic
 Gail Megason
Ph: 601-984-5220
Missouri
  Chesterfield
 Saint Luke's Hospital
 Donald Busiek, MD
Ph: 314-205-6737
  Columbia
 Ellis Fischel Cancer Center at University of Missouri - Columbia
 Clinical Trial Office - Ellis Fischel Cancer Center
Ph: 573-882-7440
  Kansas City
 Children's Mercy Hospital
 Contact Person
Ph: 816-234-3265
 Maxine Hetherington
Ph: 816-234-3265
  Saint Louis
 Arch Medical Services, Incorporated at Center for Cancer Care and Research
 Alan Lyss, MD
Ph: 314-996-5514
 Missouri Baptist Cancer Center
 Alan Lyss, MD
Ph: 314-996-5514
  Springfield
 CCOP - Cancer Research for the Ozarks
 Robert Carolla
Ph: 417-269-4520
 St. John's Regional Health Center
 Robert Carolla
Ph: 417-820-2000
Montana
  Billings
 Billings Clinic - Downtown
 Clinical Trials Office - Billings Clinic - Downtown
Ph: 800-996-2663
 Email: research@billingsclinic.org
 CCOP - Montana Cancer Consortium
 Benjamin Marchello, MD
Ph: 406-238-6290
 Hematology-Oncology Centers of the Northern Rockies - Billings
 Benjamin Marchello, MD
Ph: 406-238-6290
 Northern Rockies Radiation Oncology Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 St. Vincent Healthcare Cancer Care Services
 Benjamin Marchello, MD
Ph: 406-238-6290
  Bozeman
 Bozeman Deaconess Cancer Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Butte
 St. James Healthcare Cancer Care
 Benjamin Marchello, MD
Ph: 406-238-6290
  Great Falls
 Benjamin Marchello, MD
Ph: 406-238-6290
 Big Sky Oncology
 Clinical Trail Office - Big Sky Oncology
Ph: 406-731-8217
 Great Falls Clinic - Main Facility
 Benjamin Marchello, MD
Ph: 406-238-6290
 Sletten Cancer Institute at Benefis Healthcare
 Grant Harrer, MD, FACP, CCTI
Ph: 406-731-8100
  Havre
 Northern Montana Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Helena
 St. Peter's Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Kalispell
 Glacier Oncology, PLLC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Medical Oncology at KRMC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Regional Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Missoula
 Community Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 Guardian Oncology and Center for Wellness
 Benjamin Marchello, MD
Ph: 406-238-6290
 Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
 Clinical Trials Office - Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
Ph: 406-329-7029
 Montana Cancer Specialists at Montana Cancer Center
 Clinical Trials Office - Montana Cancer Specialists at Montana Cancer Center
Ph: 406-238-6962
Nebraska
  Lincoln
 Cancer Resource Center - Lincoln
 Alan Berg, MD
Ph: 402-420-7000
  Omaha
 Alegant Health Cancer Center at Bergan Mercy Medical Center
 Clinical Trials Office - Alegant Health Cancer Center at Bergen Mercy Medical Center
Ph: 402-398-6060
 CCOP - Missouri Valley Cancer Consortium
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Creighton University Medical Center
 Clinical Trials Office - Creighton University Medical Center
Ph: 402-280-4100
 Immanuel Medical Center
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
New Hampshire
  Lebanon
 Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
 Clinical Trials Office - Norris Cotton Cancer Center
Ph: 603-650-7609
 Email: cancerhelp@dartmouth.edu
New Jersey
  Flemington
 Hunterdon Regional Cancer Center at Hunterdon Medical Center
 Kenneth Blankstein, MD
Ph: 908-788-6100
  Hackensack
 CCOP - Northern New Jersey
 Donna McNamara
Ph: 201-996-5834
 Hackensack University Medical Center Cancer Center
 Clinical Trials Office - Hackensack University Medical Center Cancer Center
Ph: 201-996-2879
  Voorhees
 Cancer Institute of New Jersey at Cooper - Voorhees
 Clinical Trials Office - Cancer Institute of New Jersey at Cooper University Hospital - Voorhees
Ph: 856-325-6757
New Mexico
  Albuquerque
 University of New Mexico Cancer Center
 Clinical Trials Office - University of New Mexico Cancer Center
Ph: 505-272-6972
New York
  East Syracuse
 CCOP - Hematology-Oncology Associates of Central New York
 Jeffrey Kirshner, MD
Ph: 315-472-7504
  Glens Falls
 Charles R. Wood Cancer Center at Glens Falls Hospital
 Clinical Trials Office - Charles R. Wood Cancer Center at Glens Falls Hospital
Ph: 518-926-6700
  Lake Success
 Monter Cancer Center of the North Shore-LIJ Health System
 Craig DeVoe
Ph: 516-734-8959
  Manhasset
 CCOP - North Shore University Hospital
 Craig DeVoe
Ph: 516-734-8954
 Don Monti Comprehensive Cancer Center at North Shore University Hospital
 Clinical Trials Office - Don Monti Comprehensive Cancer Center at North Shore University Hospital
Ph: 516-734-8900
  New Hyde Park
 Long Island Jewish Medical Center
 Craig DeVoe
Ph: 718-470-7000
800-371-7111
  Stony Brook
 Stony Brook University Cancer Center
 Clinical Trials Office - Stony Brook University Cancer Center
Ph: 800-862-2215
  Syracuse
 SUNY Upstate Medical University Hospital
 Clinical Trials Office - SUNY Upstate Medical University Hospital
Ph: 315-464-5476
North Carolina
  Asheboro
 Randolph Hospital
 Clinical Trails Office - Randolph Hospital
Ph: 336-832-0821
  Charlotte
 Blumenthal Cancer Center at Carolinas Medical Center
 Clinical Trials Office - Blumenthal Cancer Center at Carolinas Medical Center
Ph: 704-355-2884
 Presbyterian Cancer Center at Presbyterian Hospital
 Clinical Trials Office - Presbyterian Cancer Center at Presbyterian Hospital
Ph: 704-384-5369
  Durham
 Duke Comprehensive Cancer Center
 Clinical Trials Office - Duke Comprehensive Cancer Center
Ph: 888-275-3853
  Greensboro
 Moses Cone Regional Cancer Center at Wesley Long Community Hospital
 Clinical Trials Office - Moses Cone Regional Cancer Center at Wesley Long Community Hospital
Ph: 336-621-8374
  Greenville
 Leo W. Jenkins Cancer Center at ECU Medical School
 Clinical Trials Office - Leo W. Jenkins Cancer Center at ECU Medical School
Ph: 252-744-2391
  Reidsville
 Annie Penn Cancer Center
 Clinical Trials Office - Annie Penn Cancer Center
Ph: 336-621-8374
North Dakota
  Fargo
 CCOP - MeritCare Hospital
 Preston Steen, MD
Ph: 701-234-2397
 MeritCare Broadway
 Preston Steen, MD
Ph: 701-234-2397
Ohio
  Akron
 Akron Children's Hospital
 Clinical Trials Office - Akron Children's Hospital
Ph: 330-543-3193
 Summa Center for Cancer Care at Akron City Hospital
 Clinical Trials Office - Akron City Hospital
Ph: 330-375-6101
  Bellefontaine
 Mary Rutan Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Bowling Green
 Wood County Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Canton
 Aultman Cancer Center at Aultman Hospital
 Clinical Trials Office - Aultman Cancer Center at Aultman Hospital
Ph: 330-363-6891
 Mercy Cancer Center at Mercy Medical Center
 Mitchell Haut, MD
Ph: 330-453-9993
  Chillicothe
 Adena Regional Medical Center
 Clinical Trials Office - Adena Regional Medical Center
Ph: 877-779-7585
  Cincinnati
 Charles M. Barrett Cancer Center at University Hospital
 Leslie Oleksowicz
Ph: 513-584-3200
888-640-CARE
 Christ Hospital Cancer Center
 Philip Leming, MD
Ph: 513-321-4333
  Cleveland
 Case Comprehensive Cancer Center
 Clinical Trials Office - Case Comprehensive Cancer Center
Ph: 800-641-2422
 MetroHealth Cancer Care Center at MetroHealth Medical Center
 Bruce Averbook, MD, FACS
Ph: 216-778-4795
  Clyde
 North Coast Cancer Care - Clyde
 Paul Schaefer, MD
Ph: 419-479-5605
  Columbus
 Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
 Ohio State University Cancer Clinical Trial Matching Service
Ph: 866-627-7616
 Email: osu@emergingmed.com
 CCOP - Columbus
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Doctors Hospital at Ohio Health
 Clinical Trials Office - Doctors Hospital at Ohio Health
Ph: 614-566-3275
 Grant Medical Center Cancer Care
 Clinical Trials Office - Grant Medical Center Cancer Care
Ph: 614-566-4475
 Mount Carmel Health - West Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Riverside Methodist Hospital Cancer Care
 Clinical Trials Office - Riverside Methodist Hospital Cancer Care
Ph: 614-566-4475
  Dayton
 CCOP - Dayton
 Howard Gross, MD
Ph: 937-832-1093
 Children's Medical Center - Dayton
 Emmett Broxson
Ph: 937-641-3111
 Emmett Broxson, Jr.
Ph: 937-641-3000
 David L. Rike Cancer Center at Miami Valley Hospital
 Clinical Trials Office - David L. Rike Cancer Center at Miami Valley Hospital
Ph: 937-208-2079
 Good Samaritan Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Grandview Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Samaritan North Cancer Care Center
 Howard Gross, MD
Ph: 937-832-1093
  Delaware
 Grady Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Elyria
 Hematology Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Findlay
 Blanchard Valley Medical Associates
 Howard Gross, MD
Ph: 937-832-1093
  Franklin
 Middletown Regional Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Greenville
 Wayne Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Kettering
 Charles F. Kettering Memorial Hospital
 Clinical Trials Office - Charles F. Kettering Memorial Hospital
Ph: 937-298-3399 ext. 57556
  Lancaster
 Fairfield Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Lima
 Lima Memorial Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Rita's Medical Center
 Clinical Trials Office - St. Rita's Medical Center
Ph: 419-226-9617
  Marietta
 Strecker Cancer Center at Marietta Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Maumee
 Northwest Ohio Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Luke's Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
  Newark
 Licking Memorial Cancer Care Program at Licking Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Oregon
 St. Charles Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic - Oregon
 Paul Schaefer, MD
Ph: 419-479-5605
  Sandusky
 North Coast Cancer Care, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Springfield
 Community Hospital of Springfield and Clark County
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Mercy Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Sylvania
 Flower Hospital Cancer Center
 Clinical Trials Office - Flower Hospital Cancer Center
Ph: 419-824-1842
  Tiffin
 Mercy Hospital of Tiffin
 Paul Schaefer, MD
Ph: 419-479-5605
  Toledo
 CCOP - Toledo Community Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Medical University of Ohio Cancer Center
 Clinical Trials Office - Medical University of Ohio Cancer Center
Ph: 419-383-6583
 St. Anne Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Vincent Mercy Medical Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic, Incorporated - Main Clinic
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Hospital
 Clinical Trials Office - Toledo Hospital
Ph: 419-824-1842
  Troy
 UVMC Cancer Care Center at Upper Valley Medical Center
 Clinical Trials Office - UVMC Cancer Care Center at Upper Valley Medical Center
Ph: 937-440-4842
  Wauseon
 Fulton County Health Center
 Clinical Trials Office - Fulton County Health Center
Ph: 419-330-2708
  Westerville
 Mount Carmel St. Ann's Cancer Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Wilmington
 Clinton Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Xenia
 Ruth G. McMillan Cancer Center at Greene Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Zanesville
 Genesis - Good Samaritan Hospital
 Clinical Trials Office - Genesis - Good Samaritan Hospital
Ph: 740-454-5232
Oklahoma
  Lawton
 Cleo Craig Cancer Research Clinic
 Nadim Nimeh, MD
Ph: 580-536-2121ext.113
  Oklahoma City
 Oklahoma University Cancer Institute
 Rene McNall-Knapp
Ph: 405-271-5311
 Rene McNall-Knapp
Ph: 405-271-6822
Oregon
  Gresham
 Legacy Mount Hood Medical Center
 Clinical Trials Office - Legacy Mount Hood Medical Center
Ph: 503-413-2150
  Milwaukie
 Providence Milwaukie Hospital
 Keith Lanier, MD
Ph: 503-299-6500
  Portland
 Adventist Medical Center
 Keith Lanier, MD
Ph: 503-299-6500
 CCOP - Columbia River Oncology Program
 Keith Lanier, MD
Ph: 503-299-6500
 Knight Cancer Institute at Oregon Health and Science University
 Clinical Trials Office - Knight Cancer Institute at Oregon Health and Science University
Ph: 503-494-1080
 Email: trials@ohsu.edu
 Legacy Emanuel Hospital and Health Center and Children's Hospital
 Clinical Trials Office - Legacy Emanuel Hospital and Health Center and Children's Hospital
Ph: 503-413-8199
 Legacy Good Samaritan Hospital & Comprehensive Cancer Center
 Clinical Trials Office - Legacy Good Samaritan Hospital & Comprehensive Cancer Center
Ph: 503-413-1742
 Northwest Cancer Specialists at Rose Quarter Cancer Center
 Kasra Karamlou
Ph: 503-228-6509
 Providence Cancer Center at Providence Portland Medical Center
 Clinical Trials Office - Providence Cancer Center at Providence Portland Medical Center
Ph: 503-215-6412
 Providence St. Vincent Medical Center
 Clinical Trials Office - Providence St. Vincent Medical Center
Ph: 503-215-6412
  Salem
 Salem Hospital Regional Cancer Care Services
 Clinical Trials Office - Salem Hospital Regional Cancer Care Services
Ph: 503-561-2618
  Tualatin
 Legacy Meridian Park Hospital
 Clinical Trials Office - Legacy Meridian Park Hospital
Ph: 503-413-1742
Pennsylvania
  Abington
 Rosenfeld Cancer Center at Abington Memorial Hospital
 Clinical Trials Office - Rosenfeld Cancer Center at Abington Memorial Hospital
Ph: 215-481-2402
  Allentown
 Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
 Eliot Friedman, MD
Ph: 610-402-0512
  Bethlehem
 Lehigh Valley Hospital - Muhlenberg
 Contact Person
Ph: 610-402-2273
 Philip Monteleone
Ph: 484-884-3347
 St. Luke's Cancer Network at St. Luke's Hospital
 Sanjiv Agarwala, MD
Ph: 610-954-2145
  Danville
 Geisinger Cancer Institute at Geisinger Health
 Clinical Trials Office - Geisinger Cancer Institute
Ph: 570-271-5251
  Hershey
 Penn State Cancer Institute at Milton S. Hershey Medical Center
 Clinical Trials Office - Penn State Cancer Institute at Milton S. Hershey Medical Center
Ph: 717-531-3779
 Email: CTO@hmc.psu.edu
  Lancaster
 Lancaster General Hospital
 Randall Oyer
Ph: 717-544-5511
  Lemoyne
 Central Pennsylvania Hematology and Medical Oncology Associates, PC
 John Conroy, DO, FACP, FACOI
Ph: 717-737-5767
  Lewistown
 Lewistown Hospital
 Harold Harvey, MD
Ph: 717-531-8677
  Philadelphia
 Abramson Cancer Center of the University of Pennsylvania
 Clinical Trials Office - Abramson Cancer Center of the University of Pennsylvania
Ph: 800-474-9892
 St. Christopher's Hospital for Children
 Clinical Trials Office - St. Christopher's Hospital for Children
Ph: 215-427-8991
  Pittsburgh
 UPMC Cancer Centers
 Clinical Trials Office - UPMC Cancer Centers
Ph: 412-647-8073
  Reading
 McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center
 Clinical Trials Office - McGlinn Family Regional Cancer Center
Ph: 610-988-9323
  Sayre
 Guthrie Cancer Center at Guthrie Clinic Sayre
 Clinical Trials Office - Guthrie Cancer Center at Guthrie Clinic Sayre
Ph: 800-836-0388
  Scranton
 Hematology and Oncology Associates of Northeastern Pennsylvania
 Martin Hyzinski, MD
Ph: 570-558-3020
 Mercy Hospital Cancer Center - Scranton
 Martin Hyzinski, MD
Ph: 570-558-3020
  State College
 Geisinger Medical Group - Scenery Park
 Albert Bernath, MD
Ph: 570-214-9290
 Mount Nittany Medical Center
 Harold Harvey, MD
Ph: 717-531-8677
  Wilkes-Barre
 Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
 Clinical Trials Office - Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
Ph: 570-271-5251
  Williamsport
 Susquehanna Cancer Center at Divine Providence Hospital
 Warren Robinson, Jr.
Ph: 570-326-8000
  York
 York Cancer Center at Apple Hill Medical Center
 Amir Tabatabai, MD
Ph: 717-741-9229
South Dakota
  Rapid City
 Rapid City Regional Hospital
 Richard Tenglin
Ph: 605-719-2360
  Sioux Falls
 Avera Cancer Institute
 Addison Tolentino
Ph: 605-322-3000
 Medical X-Ray Center, PC
 Loren Tschetter, MD
Ph: 605-328-8000
 Sanford Cancer Center at Sanford USD Medical Center
 Clinical Trials Office - Sanford Cancer Center
Ph: 605-328-1367
Tennessee
  Kingsport
 Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center
 Clinical Trials Office - Christine LaGuardia Phillips Cancer Center
Ph: 423-224-5593
  Knoxville
 East Tennessee Children's Hospital
 Contact Person
Ph: 865-541-8000
 Ray Pais
Ph: 865-541-8266
 Thompson Cancer Survival Center
 Clinical Trials Office - Thompson Cancer Survival Center
Ph: 865-541-1812
  Memphis
 Baptist Centers for Cancer Care
 Clinical Trials Office - Baptist Centers for Cancer Care
Ph: 901-226-3077
  Nashville
 Vanderbilt-Ingram Cancer Center
 Clinical Trials Office - Vanderbilt-Ingram Cancer Center
Ph: 800-811-8480
Texas
  Amarillo
 Harrington Cancer Center
 Clinical Trials Officec - Harrington Cancer Center
Ph: 806-359-4673
 Email: ryokubaitis@harringtoncc.org
  Dallas
 Medical City Dallas Hospital
 Peter Beitsch, MD, FACS
Ph: 972-566-8039
  San Antonio
 Methodist Children's Hospital of South Texas
 Michael Grimley
Ph: 210-575-7000
 University of Texas Health Science Center at San Antonio
 Contact Person
Ph: 210-567-4777
 Paul Thomas
Ph: 210-704-2187
  Temple
 CCOP - Scott and White Hospital
 Lucas Wong, MD
Ph: 254-724-1053
Utah
  American Fork
 American Fork Hospital
 W. Harker, MD
Ph: 801-269-0231
  Cedar City
 Sandra L. Maxwell Cancer Center
 W. Harker, MD
Ph: 801-269-0231
  Logan
 Logan Regional Hospital
 W. Harker, MD
Ph: 801-269-0231
  Murray
 Jon and Karen Huntsman Cancer Center at Intermountain Medical Center
 W. Harker, MD
Ph: 801-269-0231
  Ogden
 Val and Ann Browning Cancer Center at McKay-Dee Hospital Center
 Clinical Trials Office - McKay-Dee Hospital Center
Ph: 801 387-7426
  Provo
 Utah Valley Regional Medical Center - Provo
 Clinical Trials Office - Utah Valley Regional Medical Center - Provo
Ph: 801-357-7965
  Saint George
 Dixie Regional Medical Center - East Campus
 Clinical Trials Office - Dixie Regional Medical Center - East Campus
Ph: 435-688-4167
  Salt Lake City
 Huntsman Cancer Institute at University of Utah
 Clinical Trials Office - Huntsman Cancer Institute at University of Utah
Ph: 801-581-4477
 Email: clinical.trials@hci.utah.edu
 LDS Hospital
 W. Harker, MD
Ph: 801-269-0231
 W. Harker, MD
Ph: 801-269-0231
 Utah Cancer Specialists at UCS Cancer Center
 W. Harker, MD
Ph: 801-269-0231
Vermont
  Bennington
 Green Mountain Oncology Group
 Orion Howard
Ph: 802-442-1290
Virginia
  Charlottesville
 University of Virginia Cancer Center
 William Grosh, MD
Ph: 434-243-2911
  Danville
 Danville Regional Medical Center
 Clinical Trials Office - Danville Regional Medical Center
Ph: 434-799-3753
  Fredericksburg
 Fredericksburg Oncology, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Norton
 Southwest Virginia Regional Cancer Center at Wellmonth Health
 Malcolm Mathews, MD
Ph: 423-224-3150
Washington
  Auburn
 Auburn Regional Center for Cancer Care
 Lauren Colman, MD
Ph: 253-403-1677
  Bellingham
 St. Joseph Cancer Center
 Saul Rivkin, MD
Ph: 206-386-2441
  Bremerton
 Olympic Hematology and Oncology
 Saul Rivkin, MD
Ph: 206-386-2441
  Centralia
 Providence Centralia Hospital
 Clinical Trials Office - Providence Centralia Hospital
Ph: 360-493-4300
  Federal Way
 St. Francis Hospital
 Lauren Colman, MD
Ph: 253-403-1677
  Kennewick
 Columbia Basin Hematology
 Saul Rivkin, MD
Ph: 206-386-2441
  Olympia
 Providence St. Peter Hospital Regional Cancer Center
 Lauren Colman, MD
Ph: 253-403-1677
  Puyallup
 Good Samaritan Cancer Center
 Lauren Colman, MD
Ph: 253-403-1677
  Seattle
 Group Health Central Hospital
 Clinical Trials Office - Group Health Central Hospital
Ph: 206-287-2900
 Minor and James Medical, PLLC
 Saul Rivkin, MD
Ph: 206-386-2441
 Polyclinic First Hill
 Saul Rivkin, MD
Ph: 206-386-2441
 Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
 Saul Rivkin, MD
Ph: 206-386-2441
 University Cancer Center at University of Washington Medical Center
 Clinical Trials Office - University Cancer Center at University of Washington Medical Center
Ph: 206-616-8289
  Spokane
 Cancer Care Northwest - Spokane South
 Clinical Trials Office - Cancer Care Northwest - Spokane South
Ph: 509-228-1083
  Tacoma
 Allenmore Hospital
 Lauren Colman, MD
Ph: 253-403-1677
 CCOP - Northwest
 Lauren Colman, MD
Ph: 253-403-1677
 Franciscan Cancer Center at St. Joseph Medical Center
 Clinical Trials Office - Franciscan Cancer Center
Ph: 253-426-6914
 MultiCare Regional Cancer Center at Tacoma General Hospital
 Clinical Trials Office - MultiCare Regional Cancer Center
Ph: 253-403-3229
 St. Clare Hospital
 Lauren Colman, MD
Ph: 253-403-1677
  Vancouver
 Legacy Salmon Creek Medical Center
 Kasra Karamlou
Ph: 360-487-1000
 Southwest Washington Medical Center Cancer Center
 Keith Lanier, MD
Ph: 503-299-6500
  Yakima
 North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
 Clinical Trails Office - North Star Lodge Cancer Center
Ph: 509-574-3422
West Virginia
  Charleston
 West Virginia University Health Sciences Center - Charleston
 Steven Jubelirer, MD
Ph: 304-388-8380
  Huntington
 Edwards Comprehensive Cancer Center at Cabell Huntington Hospital
 Oncology Research Supervisor
Ph: 304-399-6617
  Parkersburg
 Community Comprehensive Cancer Center at Camden-Clark Memorial Hospital
 Clinical Trials Office - Community Comprehensive Cancer Center at Camden-Clark Memorial Hospital
Ph: 304-424-2585
Wisconsin
  Appleton
 Fox Valley Hematology and Oncology - East Grant Street
 Timothy Goggins
Ph: 920-749-1171
  Chippewa Falls
 Marshfield Clinic - Chippewa Center
 Matthias Weiss, MD
Ph: 715-358-1266
  Eau Claire
 Center for Cancer Treatment & Prevention at Sacred Heart Hospital
 Matthias Weiss, MD
Ph: 715-358-1266
 Marshfield Clinic Cancer Care at Regional Cancer Center
 Matthias Weiss, MD
Ph: 715-358-1266
  Elkhorn
 Vince Lombardi Cancer Center at Aurora Lakeland Medical Center - Elkhorn
 Rossana Madamba
Ph: 262-741-2671
800-252-2990
  Glendale
 Oncology Alliance, SC - Milwaukee - East
 Clinical Trials Office - Oncology Alliance, SC - Milwaukee - East
Ph: 414-906-4480
  Green Bay
 Green Bay Oncology, Limited at St. Mary's Hospital
 Gerald Bayer, MD
Ph: 920-432-6049
 Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
 Gerald Bayer, MD
Ph: 920-432-6049
 St. Mary's Hospital Medical Center - Green Bay
 Gerald Bayer, MD
Ph: 920-432-6049
 St. Vincent Hospital Regional Cancer Center
 Clinical Trials Office - St. Vincent Hospital Regional Cancer Center
Ph: 920-433-8889
 Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
 Clinical Trials Office - Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center
Ph: 414-649-5717
  La Crosse
 Gundersen Lutheran Center for Cancer and Blood
 Clinical Trials Office - Gundersen Lutheran Cancer Center
Ph: 608-775-2385
 Email: cancerctr@gundluth.org
  Madison
 Dean Medical Center - Madison
 Charles Diggs, MD
Ph: 608-410-2746
 University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
 Clinical Trials Office - University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
Ph: 608-262-5223
  Manitowoc
 Holy Family Memorial Medical Center Cancer Care Center
 Clinical Trials Office - Holy Family Memorial Medical Center Cancer Care Center
Ph: 920-320-2749
  Marinette
 Bay Area Cancer Care Center at Bay Area Medical Center
 Gerald Bayer, MD
Ph: 920-432-6049
 Vince Lombardi Cancer Clinic - Marinette
 Dhimant Patel, MD
Ph: 920-288-4180
  Marshfield
 Marshfield Clinic - Marshfield Center
 Clinical Trials Office - Marshfield Clinic - Marshfield Center
Ph: 800-782-1581 ext. 94457
 Saint Joseph's Hospital
 Matthias Weiss, MD
Ph: 715-358-1266
  Milwaukee
 Froedtert Hospital and Medical College of Wisconsin
 Clinical Trials Office - Froedtert Hospital
Ph: 414-805-3666
 Medical College of Wisconsin Cancer Center
 Clinical Trials Office - Medical College of Wisconsin Cancer Center
Ph: 414-805-4380
 Medical Consultants, Limited
 Jonathan Treisman, MD
Ph: 414-385-3086
  Minocqua
 Marshfield Clinic - Lakeland Center
 Matthias Weiss, MD
Ph: 715-358-1266
  Oconto Falls
 Green Bay Oncology, Limited - Oconto Falls
 Gerald Bayer, MD
Ph: 920-432-6049
  Rhinelander
 Ministry Medical Group at Saint Mary's Hospital
 Matthias Weiss, MD
Ph: 715-358-1266
  Rice Lake
 Marshfield Clinic - Indianhead Center
 Matthias Weiss, MD
Ph: 715-358-1266
  Sheboygan
 Vince Lombardi Cancer Clinic - Sheboygan
 Clinical Trials Office - Vince Lombardi Cancer Clinic - Sheboygan
Ph: 414-649-7200
  Stevens Point
 Saint Michael's Hospital Cancer Center
 Matthias Weiss, MD
Ph: 715-358-1266
  Sturgeon Bay
 Green Bay Oncology, Limited - Sturgeon Bay
 Gerald Bayer, MD
Ph: 920-432-6049
  Wausau
 Marshfield Clinic - Wausau Center
 Matthias Weiss, MD
Ph: 715-358-1266
  Weston
 Diagnostic and Treatment Center
 Matthias Weiss, MD
Ph: 715-358-1266
 Marshfield Clinic - Weston Center
 Matthias Weiss, MD
Ph: 715-358-1266
  Wisconsin Rapids
 Marshfield Clinic - Wisconsin Rapids Center
 Matthias Weiss, MD
Ph: 715-358-1266
Wyoming
  Casper
 Rocky Mountain Oncology
 Benjamin Marchello, MD
Ph: 406-238-6290
  Sheridan
 Welch Cancer Center at Sheridan Memorial Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
Australia
New South Wales
  Westmead
 Westmead Institute for Cancer Research at Westmead Hospital
 Richard Kefford, MD, MB, BS, PhD, FRACP
Ph: 61-2-9845-6033
Canada
Alberta
  Edmonton
 Cross Cancer Institute at University of Alberta
 Michael Smylie
Ph: 780-432-8757
British Columbia
  Kelowna
 British Columbia Cancer Agency - Centre for the Southern Interior
 Sanjay Chandar Rao
Ph: 250-712-3930
  Surrey
 BCCA - Fraser Valley Cancer Centre
 Gary K. Pansegrau
Ph: 604-930-4064
  Vancouver
 British Columbia Cancer Agency - Vancouver Cancer Centre
 Kerry J. Savage
Ph: 604-877-6000
  Victoria
 British Columbia Cancer Agency - Vancouver Island Centre
 Kenneth S. Wilson
Ph: 250-519-5570
Manitoba
  Winnipeg
 CancerCare Manitoba
 Ralph P.W. Wong
Ph: 204-237-2006
Nova Scotia
  Halifax
 Nova Scotia Cancer Centre
 Lori Wood
Ph: 902-473-7207
Ontario
  Barrie
 Royal Victoria Hospital of Barrie
 Bryn Pressnail
Ph: 705-728-9090
  Hamilton
 Margaret and Charles Juravinski Cancer Centre
 Richard G. Tozer
Ph: 905-387-9495
  London
 London Regional Cancer Program at London Health Sciences Centre
 Jawaid Younus
Ph: 519-685-8500
  Oshawa
 R. S. McLaughlin Durham Regional Cancer Centre at Lakeridge Health Oshawa
 Jose Chang
Ph: 905-576-8711
  St. Catharines
 St. Catharines General Hospital at Niagara Health System
 Brian Findlay
Ph: 905-684-7271
  Toronto
 Edmond Odette Cancer Centre at Sunnybrook
 Teresa M. Petrella
Ph: 416-480-5248
 Princess Margaret Hospital
 Ian Quirt
Ph: 416-946-2249
 Trillium Health Centre - Mississauga Site
 John A.P. Gapski
Ph: 416-521-4118
  Windsor
 Windsor Regional Cancer Centre at Windsor Regional Hospital
 Caroline Hamm
Ph: 519-253-5253
Quebec
  Montreal
 CHUM - Hotel Dieu Hospital
 Claude Potvin
Ph: 514-890-8000