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Basic Trial Information
Trial Description
     Summary
     Further Trial Information
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

Phase	Type	Status	Age	Sponsor	Protocol IDs
Phase III	Biomarker/Laboratory analysis, Treatment	Active	18 and over	NCI, Other	CDR0000528955 U10CA021115, ECOG-E5103, NCT00433511

Trial Description

Summary

RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of breast cancer by blocking blood flow to the tumor. Giving chemotherapy together with bevacizumab after surgery may kill any tumor cells that remain after surgery. It is not yet known whether doxorubicin, cyclophosphamide, and paclitaxel are more effective with or without bevacizumab in treating breast cancer.

PURPOSE: This randomized phase III trial is studying doxorubicin, cyclophosphamide, and paclitaxel to see how well they work with or without bevacizumab in treating patients with lymph node-positive or high-risk, lymph node-negative breast cancer.

Further Study Information

OBJECTIVES:

Primary

• Compare the disease-free survival (DFS) of patients with lymph node-positive or high-risk, lymph node-negative breast cancer treated with adjuvant therapy comprising doxorubicin hydrochloride, cyclophosphamide, and paclitaxel with vs. without bevacizumab.

Secondary

• Compare the overall survival of patients treated with these regimens.

• Determine the toxicity of these regimens.

• Compare the efficacy of short-term (20-24 weeks) vs long-term (50-54 weeks) bevacizumab, in terms of DFS, in these patients.

• Evaluate the association between outcomes (disease-free survival, overall survival and toxicities) and genotype (derived from candidate single nucleotide polymorphisms and genome wide evaluations).

• Compare quality of life patients treated with these regimens, in terms of physical symptoms, physical functioning, psychological state and social functioning over an 18 month period.

• Determine the impact of theoretical biomarker information on patients' willingness to accept the toxicities of bevacizumab for the estimated potential benefit.

OUTLINE: This is a randomized, partially double-blind, placebo-controlled, partially open-label, multicenter study. Patients are stratified according to planned dose schedule of doxorubicin hydrochloride and cyclophosphamide (every 3 weeks vs every 2 weeks). Patients are further stratified according to estrogen receptor status (positive vs negative), lymph node involvement (node-negative vs 1-3 positive node[s] vs ≥ 4 positive nodes), and received/planned treatment (lumpectomy and whole breast radiation therapy vs lumpectomy and accelerated partial-breast radiation therapy [before or after chemotherapy] vs mastectomy without radiation therapy vs mastectomy [with local or regional]). Patients are randomized to 1 of 3 treatment arms (20% of patients are randomized to Arm I, 40% to Arm II, and 40% to Arm III).

• Arm I: Patients receive doxorubicin hydrochloride IV, cyclophosphamide IV over 20-30 minutes, and placebo IV over 30-90 minutes on day 1. Treatment repeats every 2 or 3 weeks for 4 courses. Beginning 3 weeks later, patients then receive paclitaxel IV over 1 hour on days 1, 8, and 15 and placebo IV over 30-90 minutes on day 1. Treatment with paclitaxel and placebo repeats every 3 weeks for 4 courses.

• Arm II: Patients receive doxorubicin hydrochloride and cyclophosphamide as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 2 or 3 weeks for 4 courses. Beginning 3 weeks later, patients then receive paclitaxel as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment with paclitaxel and bevacizumab repeats every 3 weeks for 4 courses.

• Arm III: Patients receive doxorubicin hydrochloride and cyclophosphamide as in arm I and bevacizumab as in arm II. Treatment repeats every 2 or 3 weeks for 4 courses. Beginning 3 weeks later, patients then receive paclitaxel as in arm I and bevacizumab as in arm II. Treatment with paclitaxel and bevacizumab repeats every 3 weeks for 4 courses. Beginning 2 months later, patients then receive open-label bevacizumab IV over 30-90 minutes on day 1. Treatment with bevacizumab alone repeats every 3 weeks for 10 courses.

In all arms, treatment continues in the absence of disease progression or unacceptable toxicity. Patients complete quality of life (QOL) questionnaires followed by telephone QOL interviews at baseline and periodically.

After completion of study treatment, patients are followed periodically for up to 15 years.

PROJECTED ACCRUAL: A total of 4,950 patients will be accrued for this study.

Eligibility Criteria

DISEASE CHARACTERISTICS:

• Histologically confirmed adenocarcinoma of the breast

• Significant risk of distant recurrence based on ≥ 1 of the following criteria:

• Axillary lymph node positive disease

• At least 1 sentinal or axillary lymph node (LN) positive on routine histologic examination (must be demonstrated by more than immunohistochemistry alone)

• Intramammary nodes considered equivalent to axillary nodes

• Axillary lymph node negative disease

• LN negative with estrogen receptor (ER)-negative tumor ≥ 1 cm

• LN negative with ER+ tumor ≥ 5 cm regardless of recurrence score

• LN negative with ER+ tumor ≥ 1 cm but < 5 cm with a recurrence score ≥ 11

• Patients enrolled on ECOG-PACCT-1 clinical trial are eligible

• Has undergone definitive breast surgery within the past 29-84 days, including total mastectomy and axillary dissection (modified radical mastectomy), total mastectomy and sentinel node biopsy, lumpectomy and axillary dissection, or lumpectomy and sentinel node biopsy

• Surgical margins must be histologically free of invasive breast cancer and ductal carcinoma in situ

• Resection margins positive for lobular carcinoma in situ allowed

• Planned post-lumpectomy radiation therapy required, including any of the following:

• Whole breast radiation therapy after chemotherapy

• Accelerated partial breast radiation therapy after chemotherapy

• Accelerated partial breast radiation therapy prior to chemotherapy

• Planned post-mastectomy radiation therapy required for patients with a primary tumor of ≥ 5 cm or involvement of ≥ 4 lymph nodes

• No HER2/neu positive breast cancer (i.e., 3+ by immunohistochemistry or fluorescent in situ hybridization [FISH] ratio ≥ 2)

• No clinical evidence of inflammatory disease or fixed axillary nodes (N2) at diagnosis

• May have synchronous bilateral breast cancer (diagnosed ≤ 1 month) if the higher TNM stage tumor meets the eligibility criteria for this trial

• Hormone receptor status known

PATIENT CHARACTERISTICS:

• Male or female

• Pre- or post-menopausal

• ECOG performance status 0-1

• Absolute neutrophil count ≥ 1,000/mm³

• Platelet count ≥ 100,000/mm³

• Bilirubin ≤ 1.5 mg/dL

• AST ≤ 2 times upper limit of normal (ULN)

• Creatinine ≤ 1.5 mg/dL

• Urine protein:creatinine ratio < 1.0

• PTT ≤ 1.5 times ULN

• LVEF normal by echocardiogram or MUGA

• No clinically significant cardiovascular or cerebrovascular disease, including any of the following:

• Uncontrolled arrhythmia

• Controlled atrial fibrillation allowed

• Uncontrolled hypertension, defined as systolic blood pressure (BP) > 160 mm Hg or diastolic BP > 90 mm Hg

• Transient ischemic attack, stroke, or subarachnoid hemorrhage

• Ischemic bowel

• Myocardial infarction within the past 12 months

• Unstable angina within the past 12 months

• New York Heart Association class II-IV congestive heart failure within the past 12 months

• Peripheral vascular disease ≥ grade 2 within the past 12 months

• No bleeding diathesis, hereditary or acquired bleeding disorder, or coagulopathy

• No nonhealing wound or fracture

• No abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within the past 6 months

• No hypersensitivity to paclitaxel or drugs using the vehicle Cremophor EL, Chinese hamster ovary cell products, or other recombinant human antibodies

• Not pregnant or nursing

• Negative pregnancy test

• Fertile patients must use effective contraception during and for ≥ 3 months after completion of study treatment

PRIOR CONCURRENT THERAPY:

• See Disease Characteristics

• More than 28 days since prior major surgery

• Nonoperative biopsy not considered major surgery

• More than 24 hours since prior placement of a vascular access device

• No prior cytotoxic chemotherapy or hormonal therapy for study cancer

• May have received prior (but no concurrent) tamoxifen or raloxifene for chemoprevention

• No prior anthracycline, anthracenedione, or taxane for any condition

• Concurrent full-dose anticoagulation allowed provided the following criteria are met:

• INR in-range (usually between 2 and 3) on a stable dose of warfarin or low molecular weight heparin

• No active bleeding or pathological conditions that carry a high risk of bleeding (e.g., varices)

• Concurrrent prophylactic anticoagulants to maintain patency of a vascular access device allowed

• No concurrent cardioprotectant drugs

Trial Contact Information

Trial Lead Organizations/Sponsors

Eastern Cooperative Oncology Group

Kathy Miller

Study Chair

Ramona Swaby

Donald W. Northfelt, MD, FACP

Study Chair

Chau T. Dang

U.S.A.
Alabama
	Anniston
	Regional Medical Center
		Pramod A. Vadlamani	Ph: 256-235-5877
	Birmingham
	UAB Comprehensive Cancer Center
		Clinical Trials Office - UAB Comprehensive Cancer Center	Ph: 205-934-0309
	Mobile
	Providence Cancer Center at Providence Hospital
		Thaddeus A. Beeker	Ph: 251-633-1890
Alaska
	Anchorage
	Alaska Regional Hospital Cancer Center
		Mary L.B. Stewart	Ph: 907-276-1131
	Providence Cancer Center
		Clinical Trials Office - Providence Cancer Center	Ph: 907-261-3109
Arizona
	Scottsdale
	Mayo Clinic Scottsdale
		Clinical Trials Office - All Mayo Clinic Locations	Ph: 507-538-7623
	Premiere Oncology of Arizona
		Giraldo (Gerry) Kato	Ph: 480-860-5000
Arkansas
	Ft. Smith
	Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
		John D. Wells, MD	Ph: 479-484-4700
	Little Rock
	Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
		Clinical Trial Office - Arkansas Cancer Research Center at Uni	Ph: 501-686-8274
California
	Berkeley
	Alta Bates Summit Comprehensive Cancer Center
		Clinical Trials Office - Alta Bates Summit Comprehensive Cance	Ph: 510-204-3428
	Burbank
	Providence Saint Joseph Medical Center - Burbank
		Clinical Trials Office - Providence Saint Joseph Medical Cente	Ph: 818-847-3220
	Burlingame
	Peninsula Medical Center
		David H. Irwin, MD	Ph: 510-204-1591
	Castro Valley
	East Bay Radiation Oncology Center
		James H. Feusner, MD	Ph: 510-428-3689
	Eden Medical Center
		James H. Feusner, MD	Ph: 510-428-3689
	Valley Medical Oncology Consultants - Castro Valley
		James H. Feusner, MD	Ph: 510-428-3689
	Fremont
	Kaiser Permanente - Fremont
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Valley Medical Oncology
		James H. Feusner, MD	Ph: 510-428-3689
	Washington Township Hospital
		Byron Wilson, MD	Ph: 510-888-0657
	Fresno
	Cancer Care Associates
		Charles S. Kuzma	Ph: 559-326-1222
	Glendale
	Glendale Memorial Hospital Comprehensive Cancer Center
		Clinical Trials Office - Glendale Memorial Hospital Comprehens	Ph: 818-409-7653
	Greenbrae
	California Cancer Care, Incorporated - Greenbrae
		Peter D. Eisenberg, MD	Ph: 415-925-5000
	Marin Cancer Institute at Marin General Hospital
		David H. Irwin, MD	Ph: 510-204-1591
	Sutter Health - Western Division Cancer Research Group
		David H. Irwin, MD	Ph: 510-204-1591
	Hayward
	Kaiser Permanente Medical Center - Hayward
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	La Jolla
	Rebecca and John Moores UCSD Cancer Center
		Clinical Trials Office - Rebecca and John Moores UCSD Cancer	Ph: 858-822-5354
			Email: cancercto@ucsd.edu
	Los Angeles
	USC/Norris Comprehensive Cancer Center and Hospital
		Clinical Trials Office - USC/Norris Comprehensive Cancer Cente	Ph: 323-865-0451
	Martinez
	Contra Costa Regional Medical Center
		James H. Feusner, MD	Ph: 510-428-3689
	Monterey
	Community Hospital of the Monterey Peninsula Comprehensive Cancer Center
		John Hausdorff, MD, FACP	Ph: 831-375-4105
	Mountain View
	Camino Medical Group - Treatment Center
		Peter P. Yu, MD	Ph: 408-524-5814
	El Camino Hospital Cancer Center
		Clinical Trials Office - El Camino Hospital Cancer Center	Ph: 650-988-7623
	Oakland
	Alta Bates Summit Medical Center - Summit Campus
		Clinical Trials Office - Alta Bates Summit Medical Center - Su	Ph: 510-204-1414
	Bay Area Breast Surgeons, Incorporated
		James H. Feusner, MD	Ph: 510-428-3689
	CCOP - Bay Area Tumor Institute
		James H. Feusner, MD	Ph: 510-428-3689
	Highland General Hospital
		James H. Feusner, MD	Ph: 510-428-3689
	Kaiser Permanente Medical Center - Oakland
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Larry G Strieff MD Medical Corporation
		James H. Feusner, MD	Ph: 510-428-3689
	Tom K Lee, Incorporated
		James H. Feusner, MD	Ph: 510-428-3689
	Palm Springs
	Desert Regional Medical Center Comprehensive Cancer Center
		Clinical Trials Office - Desert Regional Medical Center Compre	Ph: 760-416-4730
	Palo Alto
	Palo Alto Medical Foundation
		Peter P. Yu, MD	Ph: 408-524-5814
	Pleasanton
	Valley Care Medical Center
		James H. Feusner, MD	Ph: 510-428-3689
	Valley Medical Oncology Consultants - Pleasanton
		James H. Feusner, MD	Ph: 510-428-3689
	Pomona
	Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center
		Clinical Trials Office - Robert and Beverly Lewis Family Cance	Ph: 909-865-9555
	Rancho Mirage
	Lucy Curci Cancer Center at Eisenhower Memorial Hospital and Medical Center
		Maria I. Popescu	Ph: 760-674-3600
	Redwood City
	Kaiser Permanente Medical Center - Redwood City
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Richmond
	Kaiser Permanente Medical Center - Richmond
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Roseville
	Kaiser Permanente Medical Center - Roseville
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Sacramento
	Kaiser Permanente Medical Center - Sacramento
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	South Sacramento Kaiser-Permanente Medical Center
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	University of California Davis Cancer Center
		Clinical Trials Office - University of California Davis Cancer	Ph: 916-734-3089
	Salinas
	Salinas Valley Memorial Hospital
		Shehzad Aziz, MD	Ph: 831-755-1701
	San Diego
	Kaiser Permanente Medical Office -Vandever Medical Office
		Jonathan A. Polikoff, MD	Ph: 619-528-5888
	Sharp Memorial Hospital Cancer Center
		Clinical Trials Office - Sharp Memorial Hospital Cancer Center	Ph: 858-939-5015
	San Francisco
	California Pacific Medical Center - California Campus
		David H. Irwin, MD	Ph: 510-204-1591
	Kaiser Permanente Medical Center - San Francisco Geary Campus
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	San Francisco General Hospital Medical Center
		Judith A. Luce, MD	Ph: 415-476-4082ext.414
	UCSF Helen Diller Family Comprehensive Cancer Center
		Clinical Trials Office - UCSF Helen Diller Family Comprehensi	Ph: 877-827-3222
	San Jose
	Kaiser Permanente Medical Center - Santa Teresa
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	San Pablo
	Doctors Medical Center - San Pablo Campus
		James H. Feusner, MD	Ph: 510-428-3689
	San Rafael
	Kaiser Foundation Hospital - San Rafael
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Santa Clara
	Kaiser Permanente Medical Center - Santa Clara Kiely Campus
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Santa Rosa
	Kaiser Permanente Medical Center - Santa Rosa
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	South San Francisco
	Kaiser Permanente Medical Center - South San Francisco
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Stanford
	Stanford Cancer Center
		Clinical Trials Office - Stanford Cancer Center	Ph: 650-498-7061
			Email: cctoffice@stanford.edu
	Stockton
	Kaiser Permanente Medical Facility - Stockton
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Vallejo
	Kaiser Permanente Medical Center - Vallejo
		Louis Fehrenbacher, MD	Ph: 707-651-2577
	Solano Clinical Research
		David H. Irwin, MD	Ph: 510-204-1591
	Walnut Creek
	Kaiser Permanente Medical Center - Walnut Creek
		Louis Fehrenbacher, MD	Ph: 707-651-2577
Colorado
	Aurora
	Aurora Presbyterian Hospital
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Boulder
	Boulder Community Hospital
		Clinical Trials Office - Boulder Community Hospital	Ph: 303-938-5253
	Colorado Springs
	Penrose Cancer Center at Penrose Hospital
		Clinical Trials Office - Penrose Cancer Center	Ph: 719-776-5275
	Denver
	CCOP - Colorado Cancer Research Program
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Porter Adventist Hospital
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Presbyterian - St. Luke's Medical Center
		Clinical Trials Office - Presbyterian - St. Luke's Medical Cen	Ph: 303-839-6000
	Rose Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	St. Anthony Central Hospital
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	St. Joseph Hospital
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Englewood
	Swedish Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Fort Collins
	Front Range Cancer Specialists
		Robert F. Marschke, Jr.	Ph: 970-212-7600
	Poudre Valley Hospital
		Clinical Trials Office - Poudre Valley Hospital	Ph: 970-495-8226
	Grand Junction
	St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Greeley
	North Colorado Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Lone Tree
	Sky Ridge Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Longmont
	Hope Cancer Care Center at Longmont United Hospital
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Loveland
	McKee Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Pueblo
	St. Mary - Corwin Regional Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Thornton
	North Suburban Medical Center
		Eduardo R. Pajon, MD	Ph: 303-399-8020ext2261
	Wheat Ridge
	Exempla Lutheran Medical Center
		Clinical Trials Office - Exempla Lutheran Medical Center	Ph: 303-403-3605
Connecticut
	Danbury
	Praxair Cancer Center at Danbury Hospital
		Robert B. Cooper, MD	Ph: 203-792-5303
	Hartford
	Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
		Zia Rahman, MD	Ph: 860-714-4593
	Norwalk
	Norwalk Hospital
		Richard C. Frank, MD	Ph: 203-845-2132
	Stamford
	Carl and Dorothy Bennett Cancer Center at Stamford Hospital
		Clinical Trials Office - Carl and Dorothy Bennett Cancer Cente	Ph: 203-323-8944
	Torrington
	Connecticut Oncology & Hematology - Torrington
		Michael C. Magnifico, MD	Ph: 860-482-5384
Delaware
	Dover
	Kent General Hospital
		Iftekhar A. Khan, MD	Ph: 302-430-5072
	Lewes
	Tunnell Cancer Center at Beebe Medical Center
		Clinical Trials Office - Tunnell Cancer Center	Ph: 302-645-3171
	Newark
	CCOP - Christiana Care Health Services
		Clinical Trial Office - CCOP - Christiana Care Health Services	Ph: 302-733-6227
District of Columbia
	Washington
	Howard University Cancer Center
		Clinical Trials Office - Howard University Cancer Center	Ph: 202-806-9122
	Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
		Clinical Trials Office - Lombardi Comprehensive Cancer Center	Ph: 202-444-0381
	Sibley Memorial Hospital
		Frederick P. Smith, MD	Ph: 301-657-4588
	Washington Cancer Institute at Washington Hospital Center
		Clinical Trials Office - Washington Cancer Institute	Ph: 202-877-8839
Florida
	Boca Raton
	Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - West
		Mohammad Jahanzeb, MD	Ph: 561-883-7500
	Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus
		Clinical Trials Office - Eugene M. and Christine E. Lynn Cance	Ph: 561-955-4800
	Dearfield Beach
	North Broward Medical Center
		Clinical Trials Office - North Broward Medical Center	Ph: 954-941-8300
	Fort Lauderdale
	Broward General Medical Center Cancer Center
		Clinical Trials Office - Broward General Medical Center Cancer	Ph: 954-355-5346
	Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
		Clinical Trials Office - Michael and Dianne Bienes Comprehensi	Ph: 954-776-3239
	Hollywood
	Memorial Cancer Institute at Memorial Regional Hospital
		Clinical Trials Office - Memorial Cancer Institute	Ph: 954-985-3443
	Jacksonville
	Mayo Clinic - Jacksonville
		Clinical Trials Office - All Mayo Clinic Locations	Ph: 507-538-7623
	Jupiter
	Ella Milbank Foshay Cancer Center at Jupiter Medical Center
		Clinical Trials Office - Ella Milbank Foshay Cancer Center	Ph: 561-745-5768
	Lakeland
	Center for Cancer Care and Research at Watson Clinic, LLP
		Clinical Trials Office - Center for Cancer Care and Research	Ph: 863-680-7780
	Lakeland Regional Cancer Center at Lakeland Regional Medical Center
		Madhavi L. Venigalla, MD	Ph: 508-368-3168
	Leesburg
	Cancer Centers of Central Florida, PA
		Glenn M. Mills, MD	Ph: 318-813-1440
	Miami
	University of Miami Sylvester Comprehensive Cancer Center - Miami
		University of Miami Sylvester Comprehensive Cancer Center Clin	Ph: 866-574-5124
			Email: Sylvester@emergingmed.com
	Miami Beach
	CCOP - Mount Sinai Medical Center
		Rogerio C. Lilenbaum, MD	Ph: 305-535-3310
	Orlando
	Florida Hospital Cancer Institute at Florida Hospital Orlando
		Clinical Trials Office - Florida Hospital Cancer Institute	Ph: 407-303-5623
	Weston
	Cleveland Clinic Florida - Weston
		Clinical Trials Office - Cleveland Clinic Florida - Weston	Ph: 954-659-5705
Georgia
	Athens
	Northeast Georgia Cancer Care, LLC - Medical Oncology
		Clinical Trials Office - Northeast Georgia Cancer Care, LLC	Ph: 706-353-5006
	Atlanta
	CCOP - Atlanta Regional
		Thomas E. Seay, MD, PhD	Ph: 404-851-2340
	Northside Hospital Cancer Center
		Clinical Trials Office - Northside Hospital Cancer Center	Ph: 404-303-3355
	Piedmont Hospital
		Thomas E. Seay, MD, PhD	Ph: 404-851-2340
	Saint Joseph's Hospital of Atlanta
		Clinical Trials Office - Saint Joseph's Hospital of Atlanta	Ph: 404-851-7115
	Augusta
	MBCCOP - Medical College of Georgia Cancer Center
		Anand P. Jillella, MD	Ph: 706-721-2505
	Austell
	WellStar Cobb Hospital
		Clinical Trials Office - WellStar Cobb Hospital	Ph: 770-793-5980
	Decatur
	Charles B. Eberhart Cancer Center at DeKalb Medical Center
		Thomas E. Seay, MD, PhD	Ph: 404-851-2340
	Fort Gordon
	Dwight David Eisenhower Army Medical Center
		Mary Edgecomb, DO	Ph: 706-787-2100
	Lawrenceville
	Gwinnett Medical Center
		Thomas E. Seay, MD, PhD	Ph: 404-851-2340
	Macon
	Medical Center of Central Georgia
		Frederick M. Schnell, MD, FACP	Ph: 478-743-7068
	Marietta
	Kennestone Cancer Center at Wellstar Kennestone Hospital
		Clinical Trials Office - Kennestone Cancer Center	Ph: 770-793-5980
	Riverdale
	Southern Regional Medical Center
		Clinical Trials Office - Southern Regional Medical Center	Ph: 770-991-8611
	Rome
	Harbin Clinic Cancer Center - Medical Oncology
		Thomas E. Seay, MD, PhD	Ph: 404-851-2340
	Savannah
	Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
		Clinical Trials Office - Curtis and Elizabeth Anderson Cancer	Ph: 912-350-8568
	Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
		Mark A. Taylor, MD	Ph: 912-354-6187
Hawaii
	Aiea
	Kapiolani Medical Center at Pali Momi
		Jonathan K. Cho	Ph: 808-486-6000
	Honolulu
	Cancer Research Center of Hawaii
		Clinical Trials Office - Cancer Research Center of Hawaii	Ph: 808-586-2979
	Hawaii Medical Center - East
		Jonathan K. Cho	Ph: 808-547-6011
	Kapiolani Medical Center for Women and Children
		Jonathan K. Cho	Ph: 808-973-8511
	OnCare Hawaii, Incorporated - Kuakini
		Jonathan K. Cho	Ph: 808-531-8521
	OnCare Hawaii, Incorporated - Lusitana
		Jonathan K. Cho	Ph: 808-524-6115
	Queen's Cancer Institute at Queen's Medical Center
		Jonathan K. Cho	Ph: 808-545-8778
	Straub Clinic and Hospital, Incorporated
		Jonathan K. Cho	Ph: 808-522-4000
	Wailuku
	Maui Memorial Medical Center
		Jonathan K. Cho	Ph: 808-244-9056
	Pacific Cancer Institute - Maui
		Jonathan K. Cho	Ph: 808-242-2600
Idaho
	Boise
	Mountain States Tumor Institute at St. Luke's Regional Medical Center
		Theodore A. Walters, MD	Ph: 208-381-2711
	Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
		Clinical Trials Office - Saint Alphonsus Cancer Care Center	Ph: 208-367-7954
	Coeur d'Alene
	Kootenai Cancer Center - Coeur d'Alene
		Clinical Trials Office - North Idaho Cancer Center	Ph: 208-666-3764
Illinois
	Alton
	Saint Anthony's Hospital at Saint Anthony's Health Center
		Bethany G. Sleckman, MD	Ph: 314-251-7057
	Berwyn
	Hematology Oncology Associates of Illinois - Berwyn
		William J. Gradishar, MD	Ph: 312-695-4125
	Bloomington
	St. Joseph Medical Center
		John W. Kugler, MD	Ph: 309-243-3605
	Canton
	Graham Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Carthage
	Memorial Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Chicago
	Hematology-Oncology Associates of Illinois
		Clinical Trails Office - Hematology and Oncology Associates	Ph: 312-695-1301
	Mount Sinai Hospital Medical Center
		Pam G. Khosla, MD	Ph: 773-542-2000
	Resurrection Medical Center
		Christopher G. Rose, MD	Ph: 847-965-3200
	Robert H. Lurie Comprehensive Cancer Center at Northwestern University
		Clinical Trials Office - Robert H. Lurie Comprehensive Cancer	Ph: 312-695-1301
			Email: cancer@northwestern.edu
	Rush Cancer Institute at Rush University Medical Center
		Clinical Trials Office - Rush University Medical Center	Ph: 312-942-5498
			Email: clinical_trials@rush.edu
	Saint Joseph Hospital
		Ira Oliff, MD	Ph: 847-673-1999
	Swedish Covenant Hospital
		K. Joseph Philip, MD	Ph: 773-784-6676
	University of Chicago Cancer Research Center
		Clinical Trials Office - University of Chicago Cancer Research	Ph: 773-834-7424
	University of Illinois Cancer Center
		Clinical Trial Office - University of Illinois Cancer Center	Ph: 312-355-3046
	Decatur
	Decatur Memorial Hospital Cancer Care Institute
		Clinical Trials Office - Decatur Memorial Hospital Cancer Care	Ph: 217-876-6601
	Elgin
	Sherman Hospital
		James L. Wade, MD	Ph: 217-876-6617
	Elk Grove Village
	Alexian Brothers Radiation Oncology
		Alkarim Tajuddin	Ph: 847-981-5760
	Elmhurst
	Elmhurst Memorial Hospital
		Gerald F. Kozuh, MD	Ph: 630-614-4060
	Eureka
	Eureka Community Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Evanston
	Evanston Hospital
		Clinical Trials Office - Evanston Hospital	Ph: 847-570-1381
	Galesburg
	Galesburg Clinic, PC
		John W. Kugler, MD	Ph: 309-243-3605
	Galesburg Cottage Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Harvey
	Ingalls Cancer Care Center at Ingalls Memorial Hospital
		Clinical Trials Office - Ingalls Cancer Care Center at Ingalls	Ph: 708-915-6747
	Havana
	Mason District Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Hinsdale
	Hinsdale Hematology Oncology Associates
		Elyse C. Schneiderman, MD	Ph: 630-654-1790
	Hopedale
	Hopedale Medical Complex
		John W. Kugler, MD	Ph: 309-243-3605
	Joliet
	Joliet Oncology-Hematology Associates, Limited - West
		Sanjiv S. Modi	Ph: 815-730-3098
	Midwest Center for Hematology/Oncology
		William J. Gradishar, MD	Ph: 312-695-4125
	Kankakee
	Provena St. Mary's Regional Cancer Center - Kankakee
		Riaz Elahi, MD	Ph: 708-873-4500
	La Grange
	La Grange Memorial Hospital
		Clinical Trials Office - La Grange Memorial Hospital	Ph: 630-856-7526
	Libertyville
	North Shore Oncology and Hematology Associates, Limited - Libertyville
		William J. Gradishar, MD	Ph: 312-695-4125
	Macomb
	McDonough District Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Maywood
	Cardinal Bernardin Cancer Center at Loyola University Medical Center
		Clinical Trials Office - Cardinal Bernardin Cancer Center	Ph: 708-226-4357
	Moline
	Study Site
		Costas L. Constantinou, MD	Ph: 563-359-9876
	Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
		Costas L. Constantinou, MD	Ph: 563-359-9876
	Mt. Vernon
	Good Samaritan Regional Health Center
		Bethany G. Sleckman, MD	Ph: 314-251-7057
	Naperville
	La Grange Oncology Associates - Geneva
		William J. Gradishar, MD	Ph: 312-695-4125
	Niles
	Cancer Care and Hematology Specialists of Chicagoland - Niles
		William J. Gradishar, MD	Ph: 312-695-4125
	Normal
	BroMenn Regional Medical Center
		John W. Kugler, MD	Ph: 309-243-3605
	Community Cancer Center
		John W. Kugler, MD	Ph: 309-243-3605
	Oak Lawn
	Advocate Christ Medical Center
		Thomas M. Hoeltgen, MD	Ph: 708-424-9710
	Ottawa
	Community Hospital of Ottawa
		John W. Kugler, MD	Ph: 309-243-3605
	Oncology Hematology Associates of Central Illinois, PC - Ottawa
		John W. Kugler, MD	Ph: 309-243-3605
	Park Ridge
	Advocate Lutheran General Cancer Care Center
		Clinical Trials Office - Advocate Lutheran General Cancer Care	Ph: 847-384-3621
	Pekin
	Cancer Treatment Center at Pekin Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Peoria
	CCOP - Illinois Oncology Research Association
		John W. Kugler, MD	Ph: 309-243-3605
	Methodist Medical Center of Illinois
		Clinical Trials Office - Methodist Medical Center of Illinois	Ph: 309-243-3000
	Oncology Hematology Associates of Central Illinois, PC - Peoria
		John W. Kugler, MD	Ph: 309-243-3605
	OSF St. Francis Medical Center
		John W. Kugler, MD	Ph: 309-243-3605
	Proctor Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Peru
	Illinois Valley Community Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Princeton
	Perry Memorial Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Rockford
	Swedish-American Regional Cancer Center
		Clinical Trials Office - Swedish-American Regional Cancer Cent	Ph: 815-489-4413
	Skokie
	Hematology Oncology Associates - Skokie
		William J. Gradishar, MD	Ph: 312-695-4125
	Spring Valley
	St. Margaret's Hospital
		John W. Kugler, MD	Ph: 309-243-3605
	Springfield
	Regional Cancer Center at Memorial Medical Center
		Clinical Trials Office - Regional Cancer Center at Memorial Me	Ph: 217-788-4233
	Winfield
	Central Dupage Cancer Center
		Laura E. Horvath	Ph: 630-933-1600
Indiana
	Beech Grove
	St. Francis Hospital and Health Centers - Beech Grove Campus
		Howard M. Gross, MD	Ph: 937-832-1093
	Elkhart
	Elkhart General Hospital
		Bilal Ansari, MD	Ph: 269-983-8260
	Fort Wayne
	Fort Wayne Medical Oncology and Hematology
		Sreenivasa R. Nattam, MD	Ph: 260-484-8830
	Goshen
	Center for Cancer Care at Goshen General Hospital
		Clinical Trials Office - Center for Cancer Care at Goshen Gene	Ph: 574-535-2858
	Indianapolis
	Indiana University Melvin and Bren Simon Cancer Center
		Clinical Trials Office - Indiana University Cancer Center	Ph: 317-274-2552
	William N. Wishard Memorial Hospital
		Kathy Miller, MD	Ph: 317-274-1690
	Kokomo
	Howard Community Hospital
		Bilal Ansari, MD	Ph: 269-983-8260
	La Porte
	Center for Cancer Therapy at LaPorte Hospital and Health Services
		Bilal Ansari, MD	Ph: 269-983-8260
	Lafayette
	Clarian Arnett Cancer Care
		Thomas I. Jones, MD	Ph: 765-448-7500
	Horizon Oncology Center
		Wael A. Harb	Ph: 765-446-5111
	Merrillville
	Suniti Medical Corporation
		Bharat H. Barai, MD	Ph: 219-736-2800
	Muncie
	Medical Consultants, PC at Ball Memorial Cancer Center
		Michael J. Williamson, Jr.	Ph: 765-281-2000
	Munster
	Community Hospital
		Erwin L. Robin, MD	Ph: 219-836-2860
	Richmond
	Reid Hospital & Health Care Services
		Howard M. Gross, MD	Ph: 937-832-1093
	South Bend
	CCOP - Northern Indiana CR Consortium
		Bilal Ansari, MD	Ph: 269-983-8260
	Memorial Hospital of South Bend
		Clinical Trials Office - Memorial Hospital of South Bend	Ph: 800-284-7370
	Saint Joseph Regional Medical Center
		Bilal Ansari, MD	Ph: 269-983-8260
	South Bend Clinic
		Bilal Ansari, MD	Ph: 269-983-8260
Iowa
	Ames
	McFarland Clinic, PC
		Clinical Trials Office - McFarland Clinic, PC	Ph: 515-239-2621
	Bettendorf
	Hematology Oncology Associates of the Quad Cities
		Shobha R. Chitneni, MD, MBBS	Ph: 563-355-7733
	Study Site
		Costas L. Constantinou, MD	Ph: 563-359-9876
	Cedar Rapids
	Cedar Rapids Oncology Associates
		Clinical Trials Office - Cedar Rapids Oncology Associates	Ph: 319-363-2690
	Iowa Blood and Cancer Care
		David O. Zenk, MD	Ph: 319-369-7091
	Mercy Regional Cancer Center at Mercy Medical Center
		Martin Wiesenfeld, MD	Ph: 319-363-8303
	Council Bluffs
	Heartland Oncology and Hematology
		John A. Okerbloom, MD	Ph: 712-322-4136
	Davenport
	Genesis Medical Center - West Campus
		George Kovach, MD	Ph: 563-421-1960
	Genesis Regional Cancer Center at Genesis Medical Center
		George Kovach, MD	Ph: 563-421-1960
	Des Moines
	CCOP - Iowa Oncology Research Association
		Roscoe F. Morton, MD, FACP	Ph: 515-282-2921
	John Stoddard Cancer Center at Iowa Lutheran Hospital
		Clinical Trials Office - John Stoddard Cancer Center at Iowa L	Ph: 515-241-8704
	John Stoddard Cancer Center at Iowa Methodist Medical Center
		Clinical Trials Office - John Stoddard Cancer Center at Iowa M	Ph: 515-241-6727
	Medical Oncology and Hematology Associates at John Stoddard Cancer Center
		Roscoe F. Morton, MD, FACP	Ph: 515-282-2921
	Medical Oncology and Hematology Associates at Mercy Cancer Center
		Roscoe F. Morton, MD, FACP	Ph: 515-282-2921
	Mercy Cancer Center at Mercy Medical Center - Des Moines
		Roscoe F. Morton, MD, FACP	Ph: 515-282-2921
	Mercy Capitol Hospital
		Roscoe F. Morton, MD, FACP	Ph: 515-282-2921
	Mason City
	Mercy Cancer Center at Mercy Medical Center - North Iowa
		Clinical Trials Office - Mercy Cancer Center at Mercy Medical	Ph: 641-422-6304
	Ottumwa
	McCreery Cancer Center at Ottumwa Regional
		Roscoe F. Morton, MD, FACP	Ph: 515-282-2921
	Sioux City
	Mercy Medical Center - Sioux City
		Donald B. Wender, MD, PhD	Ph: 712-252-0088
	Siouxland Hematology-Oncology Associates, LLP
		Donald B. Wender, MD, PhD	Ph: 712-252-0088
	St. Luke's Regional Medical Center
		Donald B. Wender, MD, PhD	Ph: 712-252-0088
	Waterloo
	Covenant Cancer Treatment Center
		Clinical Trials Office - Covenant Cancer Treatment Center	Ph: 319-272-2070
Kansas
	Chanute
	Cancer Center of Kansas, PA - Chanute
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Dodge City
	Cancer Center of Kansas, PA - Dodge City
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	El Dorado
	Cancer Center of Kansas, PA - El Dorado
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Independence
	Cancer Center of Kansas-Independence
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Kansas City
	Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
		Clinical Trials Office - Kansas Masonic Cancer Research Instit	Ph: 913-588-4709
	Kingman
	Cancer Center of Kansas, PA - Kingman
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Lawrence
	Lawrence Memorial Hospital
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Liberal
	Southwest Medical Center
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Newton
	Cancer Center of Kansas, PA - Newton
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Olathe
	Olathe Cancer Center
		Karen Kelly, MD	Ph: 303-724-3903
	Parsons
	Cancer Center of Kansas, PA - Parsons
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Pratt
	Cancer Center of Kansas, PA - Pratt
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Salina
	Cancer Center of Kansas, PA - Salina
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Topeka
	Cotton-O'Neil Cancer Center
		Clinical Trials Office - Cotton-O'Neil Cancer Center	Ph: 785-270-4963
	St. Francis Comprehensive Cancer Center
		Michael A. Hurwitz, MD	Ph: 785-295-7800
	Wellington
	Cancer Center of Kansas, PA - Wellington
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Wichita
	Associates in Womens Health, PA - North Review
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Wichita
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Medical Arts Tower
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	CCOP - Wichita
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Via Christi Cancer Center at Via Christi Regional Medical Center
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
	Winfield
	Cancer Center of Kansas, PA - Winfield
		Shaker R. Dakhil, MD, FACP	Ph: 316-262-4467
Kentucky
	Louisville
	James Graham Brown Cancer Center at University of Louisville
		Dharamvir Jain	Ph: 502-562-4158
Louisiana
	Baton Rouge
	Mary Bird Perkins Cancer Center - Baton Rouge
		Robert W. Veith	Ph: 225-767-0847
	Ochsner Health Center - Bluebonnet
		John T. Cole	Ph: 225-761-5200
	Pennington Cancer Center at Baton Rouge General
		Clinical Trials Office - Pennington Cancer Center at Baton Rou	Ph: 225-381-6451
	Mansfield
	DeSoto Regional Hospital
		Glenn M. Mills, MD	Ph: 318-813-1440
	Monroe
	Louisiana State University Health Sciences Center - Monroe
		Glenn M. Mills, MD	Ph: 318-813-1440
	New Orleans
	CCOP - Ochsner
		John T. Cole	Ph: 504-842-3910
	MBCCOP - LSU Health Sciences Center
		Robert W. Veith	Ph: 504-568-5151
	Medical Center of Louisiana - New Orleans
		Robert W. Veith	Ph: 504-903-2311
	Ochsner Cancer Institute at Ochsner Clinic Foundation
		John T. Cole	Ph: 504-842-4360
	Shreveport
	Feist-Weiller Cancer Center at Louisiana State University Health Sciences
		Clinical Trials Office - Feist-Weiller Cancer Center at Louisi	Ph: 318-813-1412
	Highland Clinic
		Glenn M. Mills, MD	Ph: 318-813-1440
Maine
	Bangor
	CancerCare of Maine at Eastern Maine Medical Center
		Clinical Trials Office - CancerCare of Maine	Ph: 207-973-4274
	Scarborough
	Maine Center for Cancer Medicine and Blood Disorders - Scarborough
		Tracey F. Weisberg, MD	Ph: 207-885-7634
	Waterville
	MaineGeneral Medical Center - Waterville
		Clinical Trials Office - MaineGeneral Medical Center - Watervi	Ph: 207-872-1792
	York
	York Hospital's Oncology Treatment Center
		Jonathan D. Eneman	Ph: 207-351-3777
Maryland
	Annapolis
	DeCesaris Cancer Institute at Anne Arundel Medical Center
		Jeanine L. Werner, MD	Ph: 410-573-5300
	Baltimore
	Greater Baltimore Medical Center Cancer Center
		Clinical Trials Office - Greater Baltimore Medical Center Canc	Ph: 443-849-3706
	Greenebaum Cancer Center at University of Maryland Medical Center
		Clinical Trials Office - Greenebaum Cancer Center at Universit	Ph: 800-888-8823
	Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
		Clinical Trials Office - Harry & Jeanette Weinberg Cancer Inst	Ph: 443-777-7364
	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
		Clinical Trials Office - Sidney Kimmel Comprehensive Cancer Ce	Ph: 410-955-8804
			Email: jhcccro@jhmi.edu
	Bethesda
	Suburban Hospital
		G. P. Pushkas	Ph: 301-896-3021
	Easton
	Shore Regional Cancer Center at Memorial Hospital - Easton
		Mary S. DeShields, MD	Ph: 410-819-3332
	Elkton Md
	Union Hospital Cancer Program at Union Hospital
		Gregory A. Masters, MD	Ph: 302-366-1200
	Frederick
	Frederick Memorial Hospital Regional Cancer Therapy Center
		Brian M. O'Connor, MD	Ph: 301-662-8477
	Kensington
	Associates in Oncology and Hematology
		Paul M. Thambi	Ph: 301-929-0765
	Rockville
	Associates in Oncology and Hematology - Medical Center Drive
		Paul M. Thambi	Ph: 301-424-6231
Massachusetts
	Boston
	Beth Israel Deaconess Medical Center
		Clinical Trials Office - Beth Israel Deaconess Medical Center	Ph: 617-667-9925
	Boston University Cancer Research Center
		Clinical Trials Office - Boston University Cancer Research Cen	Ph: 617-353-7571
	Dana-Farber/Brigham and Women's Cancer Center
		Clinical Trials Office	Ph: 617-724-5200
	Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute
		Steven E. Come, MD	Ph: 617-667-4599
	Massachusetts General Hospital
		Clinical Trials Office - Massachusetts General Hospital	Ph: 877-726-5130
	Tufts-NEMC Cancer Center
		Kathy P. Theall, MD	Ph: 617-636-2520
	Brighton
	Caritas St. Elizabeth's Medical Center
		Elizabeth M. Blanchard	Ph: 617-789-3000
	Burlington
	Lahey Clinic Medical Center - Burlington
		Clinical Trials Office - Lahey Clinic Medical Center - Burling	Ph: 781-744-8027
	Framingham
	MetroWest Medical Center - Framingham Union Hospital
		Kala Seetharaman	Ph: 508-383-1000
	Gloucester
	Addison Gilbert Hospital
		Angus P. McIntyre, MD	Ph: 978-927-6850
	Hyannis
	Cape Cod Hospital
		Steven E. Come, MD	Ph: 617-667-4599
	Pittsfield
	Berkshire Hematology Oncology, PC
		Harvey Zimbler, MD	Ph: 413-496-8205
	Springfield
	Baystate Regional Cancer Program at D'Amour Center for Cancer Care
		James A. Stewart, MD	Ph: 608-265-8131
Michigan
	Ann Arbor
	CCOP - Michigan Cancer Research Consortium
		Philip J. Stella, MD	Ph: 734-712-1000
	Saint Joseph Mercy Cancer Center
		Philip J. Stella, MD	Ph: 734-712-1000
	Battle Creek
	Battle Creek Health System Cancer Care Center
		Martin J. Bury	Ph: 616-966-8000
	Big Rapids
	Mecosta County Medical Center
		Martin J. Bury	Ph: 231-796-8691
	Dearborn
	Oakwood Cancer Center at Oakwood Hospital and Medical Center
		Clinical Trials Office - Oakwood Cancer Center at Oakwood Hosp	Ph: 313-593-8090
	Detroit
	Barbara Ann Karmanos Cancer Institute
		Clinical Trials Office - Barbara Ann Karmanos Cancer Institute	Ph: 313-576-9363
	Escanaba
	Green Bay Oncology, Limited - Escanaba
		Gerald K. Bayer, MD	Ph: 920-432-6049
	Flint
	Genesys Hurley Cancer Institute
		Clinical Trials Office - Genesys Hurley Cancer Institute	Ph: 810-762-8057
	Hurley Medical Center
		Clinical Trials Office - Hurley Medical Center	Ph: 810-762-8057
	Grand Rapids
	Butterworth Hospital at Spectrum Health
		Martin J. Bury	Ph: 616-391-2799
	CCOP - Grand Rapids
		Martin J. Bury	Ph: 616-391-1230
	Lacks Cancer Center at Saint Mary's Health Care
		Martin J. Bury	Ph: 616-752-5222
	Grosse Pointe Woods
	Van Elslander Cancer Center at St. John Hospital and Medical Center
		Clincial Trials Office - Van Elslander Cancer Center at St. Jo	Ph: 313-343-3166
	Iron Mountain
	Dickinson County Healthcare System
		Gerald K. Bayer, MD	Ph: 920-432-6049
	Jackson
	Foote Memorial Hospital
		Philip J. Stella, MD	Ph: 734-712-1000
	Kalamazoo
	Borgess Medical Center
		Raymond S. Lord, MD	Ph: 269-373-7458
	Bronson Methodist Hospital
		Raymond S. Lord, MD	Ph: 269-373-7458
	West Michigan Cancer Center
		Clinical Trials Office - West Michigan Cancer Center	Ph: 269-373-7458
	Lansing
	Sparrow Regional Cancer Center
		Clinical Trials Office - Sparrow Regional Cancer Center	Ph: 517-364-2890
	Livonia
	St. Mary Mercy Hospital
		Philip J. Stella, MD	Ph: 734-712-1000
	Midland
	MidMichigan Medical Center - Midland
		Clinical Trials Office - MidMichigan Medical Center - Midland	Ph: 989-839-3377
	Mount Clemens
	Clemens Regional Medical Center
		Clinical Trials Office - Ted B. Wahby Cancer Center at Mount C	Ph: 586-493-3426
	Muskegon
	Mercy General Health Partners
		Martin J. Bury	Ph: 231-672-2000
	Pontiac
	St. Joseph Mercy Oakland
		Philip J. Stella, MD	Ph: 734-712-1000
	Port Huron
	Mercy Regional Cancer Center at Mercy Hospital
		Philip J. Stella, MD	Ph: 734-712-1000
	Royal Oak
	William Beaumont Hospital - Royal Oak Campus
		Clinical Trials Office - William Beaumont Hospital - Royal Oak	Ph: 248-551-7695
	Saginaw
	Seton Cancer Institute at Saint Mary's - Saginaw
		Clinical Trials Office - Seton Cancer Institute - Saginaw	Ph: 989-776-8411
	Saint Joseph
	Oncology Care Associates, PLLC
		Eric P. Lester, MD	Ph: 269-985-0029
	Southfield
	Providence Cancer Institute at Providence Hospital - Southfield Campus
		Lyle Goldman, MD	Ph: 248-552-0620
	St. Joseph
	Lakeland Regional Cancer Care Center - St. Joseph
		Bilal Ansari, MD	Ph: 269-983-8260
	Traverse City
	Munson Medical Center
		Martin J. Bury	Ph: 231-935-6202
	Warren
	St. John Macomb Hospital
		Philip J. Stella, MD	Ph: 734-712-1000
	Wyoming
	Metro Health Hospital
		Martin J. Bury	Ph: 616-252-7200
Minnesota
	Alexandria
	Study Site
		Donald J. Jurgens	Ph: 320-229-4907
	Bemidji
	MeritCare Bemidji
		Preston D. Steen, MD	Ph: 701-234-2397
	Burnsville
	Fairview Ridges Hospital
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Coon Rapids
	Mercy and Unity Cancer Center at Mercy Hospital
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Duluth
	CCOP - Duluth
		Daniel Nikcevich, MD, PhD	Ph: 218-786-3625
	Duluth Clinic Cancer Center - Duluth
		Clinical Trials Office - Duluth Clinic Cancer Center - Duluth	Ph: 218-786-3308
	Miller - Dwan Medical Center
		Daniel Nikcevich, MD, PhD	Ph: 218-786-3625
	St. Luke's Hospital Cancer Care Center
		Tanya L. Repka, MD, FACP	Ph: 218-726-3081
	Edina
	Fairview Southdale Hospital
		Clinical Trials Office - Fairview Southdale Hospital	Ph: 612-625-3650
	Fergus Falls
	Study Site
		Donald J. Jurgens	Ph: 320-229-4907
	Fridley
	Mercy and Unity Cancer Center at Unity Hospital
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Hutchinson
	Hutchinson Area Health Care
		Daniel M. Anderson	Ph: 320-234-5000
	Lichfield
	Meeker County Memorial Hospital
		Clinical Trials Office - Meeker County Memorial Hospital	Ph: 320-693-4520
	Mankato
	Immanuel St. Joseph's
		Glenn S. Harman, MD	Ph: 815-777-1536
	Maplewood
	HealthEast Cancer Care at St. John's Hospital
		Daniel M. Anderson	Ph: 651-232-7970
	Minnesota Oncology Hematology, PA - Maplewood
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Minneapolis
	Hennepin County Medical Center - Minneapolis
		Clinical Trials Office - Hennepin County Medical Center - Minn	Ph: 612-873-5911
	Masonic Cancer Center at University of Minnesota
		Clinical Trials Office - Masonic Cancer Center at University o	Ph: 612-624-2620
	Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
		Clinical Trials Office - Virginia Piper Cancer Institute	Ph: 612-863-5654
	Robbinsdale
	Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
		Clinical Trials Office - Hubert H. Humphrey Cancer Center at N	Ph: 763-520-1893
	Rochester
	Mayo Clinic Cancer Center
		Clinical Trials Office - All Mayo Clinic Locations	Ph: 507-538-7623
	Saint Cloud
	CentraCare Clinic - River Campus
		Donald J. Jurgens	Ph: 320-229-4907
	Coborn Cancer Center
		Donald J. Jurgens	Ph: 320-229-4907
	Saint Louis Park
	CCOP - Metro-Minnesota
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Park Nicollet Cancer Center
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Saint Paul
	United Hospital
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Shakopee
	St. Francis Cancer Center at St. Francis Medical Center
		Patrick J. Flynn, MD	Ph: 612-863-8585
	St. Paul
	Regions Hospital Cancer Care Center
		Clinical Trials Office - Regions Hospital Cancer Care Center	Ph: 651-254-1517
	Waconia
	Ridgeview Medical Center
		Patrick J. Flynn, MD	Ph: 612-863-8585
	Willmar
	Willmar Cancer Center at Rice Memorial Hospital
		Joseph M. Ryan, MD	Ph: 320-231-6359
	Woodbury
	Minnesota Oncology Hematology, PA - Woodbury
		Patrick J. Flynn, MD	Ph: 612-863-8585
Mississippi
	Kessler AFB
	Keesler Air Force Base Medical Center
		Louis M. Varner	Ph: 228-377-2086
Missouri
	Cape Girardeau
	Saint Francis Medical Center
		Bethany G. Sleckman, MD	Ph: 314-251-7057
	Southeast Missouri Regional Cancer Center at Southeast Missouri Hospital
		Bethany G. Sleckman, MD	Ph: 314-251-7057
	Chesterfield
	Saint Luke's Hospital
		Donald F. Busiek, MD	Ph: 314-205-6737
	Columbia
	Ellis Fischel Cancer Center at University of Missouri - Columbia
		Clinical Trial Office - Ellis Fischel Cancer Center	Ph: 573-882-4894
	Joplin
	Freeman Cancer Institute at Freeman Health System
		Anisa Hassan	Ph: 417-347-3066
	St. John's Regional Medical Center
		Clinical Trials Office - St. John's Regional Medical Center	Ph: 417-625-2488 ext. 2949
	Saint Louis
	Arch Medical Services, Incorporated at Center for Cancer Care and Research
		Alan P. Lyss, MD	Ph: 314-996-5514
	CCOP - St. Louis-Cape Girardeau
		Bethany G. Sleckman, MD	Ph: 314-251-7057
	David C. Pratt Cancer Center at St. John's Mercy
		Clinical Trials Office - David C. Pratt Cancer Center at St. J	Ph: 314-251-6770
	Midwest Hematology Oncology Group, Incorporated
		Bethany G. Sleckman, MD	Ph: 314-251-7057
	Missouri Baptist Cancer Center
		Alan P. Lyss, MD	Ph: 314-996-5514
	Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
		Michael J. Naughton, MD	Ph: 314-996-8872
	Springfield
	CCOP - Cancer Research for the Ozarks
		Robert L. Carolla	Ph: 417-269-4520
	Hulston Cancer Center at Cox Medical Center South
		Robert L. Carolla	Ph: 417-269-5257
	St. John's Regional Health Center
		Robert L. Carolla	Ph: 417-820-2000
Montana
	Billings
	Billings Clinic - Downtown
		Clinical Trials Office - Billings Clinic - Downtown	Ph: 800-996-2663
			Email: research@billingsclinic.org
	CCOP - Montana Cancer Consortium
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Hematology-Oncology Centers of the Northern Rockies - Billings
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Northern Rockies Radiation Oncology Center
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	St. Vincent Healthcare Cancer Care Services
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Butte
	St. James Healthcare Cancer Care
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Great Falls
	Big Sky Oncology
		Clinical Trail Office - Big Sky Oncology	Ph: 406-731-8217
	Great Falls Clinic - Main Facility
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Sletten Cancer Institute at Benefis Healthcare
		Contact Person	Ph: 406-731-8200
	Study Site
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Havre
	Northern Montana Hospital
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Helena
	St. Peter's Hospital
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Kalispell
	Glacier Oncology, PLLC
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Kalispell Medical Oncology at KRMC
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Kalispell Regional Medical Center
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Missoula
	Community Medical Center
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Guardian Oncology and Center for Wellness
		Benjamin T. Marchello, MD	Ph: 406-238-6290
	Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
		Clinical Trials Office - Montana Cancer Center at St. Patrick	Ph: 406-329-7029
	Montana Cancer Specialists at Montana Cancer Center
		Clinical Trials Office - Montana Cancer Specialists at Montana	Ph: 406-238-6962
Nebraska
	Lincoln
	Cancer Resource Center - Lincoln
		Alan R. Berg, MD	Ph: 402-420-7000
	Omaha
	Alegant Health Cancer Center at Bergan Mercy Medical Center
		Clinical Trials Office - Alegant Health Cancer Center at Berge	Ph: 402-398-6060
	CCOP - Missouri Valley Cancer Consortium
		Gamini S. Soori, MD, FACP, FRCP, MBA	Ph: 402-393-3110
	Creighton University Medical Center
		Clinical Trials Office - Creighton University Medical Center	Ph: 402-280-4100
	Immanuel Medical Center
		Gamini S. Soori, MD, FACP, FRCP, MBA	Ph: 402-393-3110
	Methodist Estabrook Cancer Center
		Robert M. Langdon, MD	Ph: 402-399-8762
Nevada
	Las Vegas
	CCOP - Nevada Cancer Research Foundation
		Contact Person	Ph: 702-384-0013
	University Medical Center of Southern Nevada
		Contact Person	Ph: 702-383-2000
New Hampshire
	Concord
	New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
		Charles H. Catcher, MD	Ph: 603-224-2556
	Dover
	Seacoast Cancer Center at Wentworth - Douglass Hospital
		Barbara Shea, MD	Ph: 603-740-2390
	Exeter
	Center for Cancer Care at Exeter Hospital
		Danny M. Sims	Ph: 603-580-6636
	Hooksett
	New Hampshire Oncology - Hematology, PA - Hooksett
		Charles H. Catcher, MD	Ph: 603-224-2556
	Laconia
	Lakes Region General Hospital
		Charles H. Catcher, MD	Ph: 603-224-2556
New Jersey
	Brick
	Ocean Medical Center at Meridian Health
		Clinical Trials Office - Ocean Medical Center at Meridian Heal	Ph: 732-206-8384
	Englewood
	Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center
		Clinical Trials Office - Dizzy Gillespie Cancer Institute at E	Ph: 201-894-3456
	Flemington
	Hunterdon Regional Cancer Center at Hunterdon Medical Center
		Kenneth B. Blankstein, MD	Ph: 908-788-6100
	Hackensack
	CCOP - Northern New Jersey
		Stanley E. Waintraub, MD, FACP	Ph: 201-996-5900
	Hamilton
	Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
		Clinical Trials Office - Cancer Institute of New Jersey at Ham	Ph: 609-631-6946
	Livingston
	St. Barnabas Medical Center Cancer Center
		Clinical Trials Office - St. Barnabas Medical Center Cancer Ce	Ph: 973-322-2470
	Marlton
	Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton
		Clinical Trials Office - Fox Chase Virtua Health Cancer Progra	Ph: 888-847-8823
	Morristown
	Carol G. Simon Cancer Center at Morristown Memorial Hospital
		Bonni L. Gearhart	Ph: 973-971-6100
	Neptune
	Jersey Shore Cancer Center at Jersey Shore University Medical Center
		Kenneth D. Nahum, DO, FACP	Ph: 732-367-1535
	New Brunswick
	Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
		Clinical Trials Office - Cancer Institute of New Jersey	Ph: 732-235-8675
	Saint Peter's University Hospital
		Edward J. Licitra	Ph: 732-745-8600
	Newark
	Newark Beth Israel Medical Center
		Clinical Trials Office - Newark Beth Israel Medical Center	Ph: 973-926-3136
	Pomona
	AtlantiCare Cancer Care Institute at AtlantiCare Regional Medical Center - Mainland Campus
		Julianne W. Childs, DO, FACOI	Ph: 609-390-7888
	Red Bank
	Booker Cancer Center at Riverview Medical Center
		Denis B. Fitzgerald, MD	Ph: 732-530-8666
	Ridgewood
	Valley Hospital - Ridgewood
		Eli D. Kirshner	Ph: 201-634-5339
	Sparta
	Frederick R. and Betty M. Smith Cancer Treatment Center
		Ronald I. Cantor	Ph: 973-726-4180
	Summit
	Overlook Hospital
		Bonni L. Gearhart	Ph: 908-522-2000
	Trenton
	Capital Health Regional Cancer Center
		Scott K. Kindsfather	Ph: 609-396-5800
	Vineland
	Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare
		Clinical Trials Office - Franklin & Edith Scarpa Regional Canc	Ph: 856-641-7933
	Voorhees
	Cancer Institute of New Jersey at Cooper - Voorhees
		Clinical Trials Office - Cancer Institute of New Jersey at Coo	Ph: 856-325-6757
	Fox Chase Virtua Health Cancer Program at Virtua West Jersey
		Michael S. Entmacher, MD	Ph: 609-702-1900
New Mexico
	Albuquerque
	Hematology Oncology Associates, PC
		Melanie E. Royce, MD, PhD	Ph: 505-272-6057
	Lovelace Medical Center - Downtown
		Melanie E. Royce, MD, PhD	Ph: 505-272-6057
	Presbyterian Cancer Treatment Center at Presbyterian Kaseman Hospital
		Melanie E. Royce, MD, PhD	Ph: 505-272-6057
	University of New Mexico Cancer Center
		Clinical Trials Office - University of New Mexico Cancer Cente	Ph: 505-272-6972
	Las Cruces
	University of New Mexico Cancer Center - South
		Melanie E. Royce, MD, PhD	Ph: 505-272-6057
New York
	Albany
	New York Oncology Hematology, PC at Albany Medical Center
		Charles H. Weissman	Ph: 518-262-6696
	New York Oncology Hematology, PC at Albany Regional Cancer Care
		Charles H. Weissman	Ph: 518-489-2607
	Amsterdam
	Amsterdam Community Cancer Program
		Charles H. Weissman	Ph: 518-843-0020
	Bronx
	Albert Einstein Cancer Center at Albert Einstein College of Medicine
		Clinical Trials Office - Albert Einstein Cancer Center at Albe	Ph: 718-904-2730
			Email: aecc@aecom.yu.edu
	Lincoln Medical and Mental Health Center
		Doru Paul	Ph: 718-579-5000
	Our Lady of Mercy Medical Center Comprehensive Cancer Center
		Peter H. Wiernik, MD	Ph: 718-304-7200
	Brooklyn
	Coney Island Hospital
		Jack D Burton	Ph: 718-616-3000
	Maimonides Cancer Center at Maimonides Medical Center
		Alan B. Astrow	Ph: 718-765-2520
	Buffalo
	Roswell Park Cancer Institute
		Clinical Trials Office - Roswell Park Cancer Institute	Ph: 877-275-7724
	Clifton Springs
	Finger Lakes Hematology and Oncology
		Bruce A. Yirinec, MD	Ph: 315-462-6929
	Cooperstown
	Bassett Healthcare Regional Cancer Program at Mary Imogene Bassett Hospital
		Eric Bravin, MD	Ph: 607-547-3336
	East Syracuse
	CCOP - Hematology-Oncology Associates of Central New York
		Jeffrey J. Kirshner, MD	Ph: 315-472-7504
	Elmhurst
	Elmhurst Hospital Center
		Clinical Trials Office - Elmhurst Hospital Center	Ph: 718-883-3177
	Elmira
	Falck Cancer Center at Arnot Ogden Medical Center
		Clinical Trials Office - Falck Cancer Center at Arnot Ogden Me	Ph: 607-271-7000
	Hudson
	New York Oncology Hematology, PC - Hudson
		Charles H. Weissman	Ph: 518-822-8484
	Jamaica
	Queens Cancer Center of Queens Hospital
		Myra F. Barginear	Ph: 718-883-4031
	Latham
	New York Oncology Hematology, PC - Latham
		Charles H. Weissman	Ph: 518-786-3122
	Middletown
	Tucker Center for Cancer Care at Orange Regional Medical Center
		Clinical Trials Office - Tucker Center for Cancer Care at Oran	Ph: 845-342-7609
	Mount Kisco
	Northern Westchester Hospital
		Jonathan S. Goldberg	Ph: 914-666-1200
	New York
	Beth Israel Medical Center - Petrie Division
		Clinical Trials Office - Beth Israel Medical Center - Petrie D	Ph: 212-844-6286
	Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
		Clinical Trials Office - Herbert Irving Comprehensive Cancer C	Ph: 212-305-8615
	Memorial Sloan-Kettering Cancer Center
		Chau T. Dang	Ph: 212-639-8895
	Mount Sinai Medical Center
		Myra F. Barginear	Ph: 212-241-6500
	New York Weill Cornell Cancer Center at Cornell University
		Clinical Trials Office - New York Weill Cornell Cancer Center	Ph: 212-746-1848
	NYU Cancer Institute at New York University Medical Center
		Amy D. Tiersten, MD	Ph: 212-731-5349
	St. Luke's - Roosevelt Hospital Center - St.Luke's Division
		Stephen C. Malamud, MD	Ph: 212-844-8280
	St. Vincent's Comprehensive Cancer Center - Manhattan
		Clinical Trials Office - St. Vincent's Comprehensive Cancer Ce	Ph: 212-367-1729
	Plattsburgh
	Fitzpatrick Cancer Center at Champlain Valley Physicians Hospital Medical Center
		Jan E. Duus, MD	Ph: 518-562-7110
	Poughkeepsie
	Dyson Center for Cancer Care at Vassar Brothers Medical Center
		Clinical Trials Office - Dyson Center for Cancer Care at Vassa	Ph: 845-483-6483
	Rexford
	Riverview Cancer Care Medical Associates, PC
		Charles H. Weissman	Ph: 518-399-4600
	Rochester
	Highland Hospital of Rochester
		Richard I. Fisher, MD	Ph: 585-275-0842
	Interlakes Oncology/Hematology PC
		Richard I. Fisher, MD	Ph: 585-275-0842
	James P. Wilmot Cancer Center at University of Rochester Medical Center
		Richard I. Fisher, MD	Ph: 585-275-0842
	Staten Island
	Nalitt Cancer Institute at Staten Island University Hospital
		Marcel Odaimi	Ph: 718-226-6400
	Stony Brook
	Stony Brook University Cancer Center
		Clinical Trials Office - Stony Brook University Cancer Center	Ph: 800-862-2215
	Syracuse
	SUNY Upstate Medical University Hospital
		Clinical Trials Office - SUNY Upstate Medical University Hospi	Ph: 315-464-5476
	Troy
	Samaritan Hospital at Northeast Health
		Charles H. Weissman	Ph: 518-271-3775
	Utica
	Faxton Regional Cancer Center
		Atul Butala, MD, FACP	Ph: 315-798-9300
North Carolina
	Asheboro
	Randolph Hospital
		Clinical Trails Office - Randolph Hospital	Ph: 336-832-0821
	Asheville
	Hope A Women's Cancer Center
		David J. Hetzel, MD	Ph: 828-670-8403
	Mission Hospitals - Memorial Campus
		Clinical Trials Office - Mission Hospitals - Memorial Campus	Ph: 828-213-4150
	Burlington
	Alamance Cancer Center at Alamance Regional Medical Center
		Janak K. Choksi, MD	Ph: 336-538-7737
	Cary
	Waverly Hematology Oncology
		Mark L. Graham, MD	Ph: 919-233-8585
	Chapel Hill
	Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
		Clinical Trials Office - Lineberger Comprehensive Cancer Cente	Ph: 877-668-0683; 919-966-4432
	Charlotte
	Presbyterian Cancer Center at Presbyterian Hospital
		Clinical Trials Office - Presbyterian Cancer Center at Presbyt	Ph: 704-384-5369
	Concord
	Batte Cancer Center at Northeast Medical Center
		James G. Wall, MD	Ph: 704-783-1370
	Goldsboro
	Wayne Memorial Hospital, Incorporated
		James N. Atkins, MD	Ph: 919-580-0000
	Greensboro
	Moses Cone Regional Cancer Center at Wesley Long Community Hospital
		Clinical Trials Office - Moses Cone Regional Cancer Center at	Ph: 336-621-8374
	Greenville
	Leo W. Jenkins Cancer Center at ECU Medical School
		Clinical Trials Office - Leo W. Jenkins Cancer Center at ECU M	Ph: 252-744-2391
	Hendersonville
	Pardee Memorial Hospital
		James E. Radford, MD	Ph: 828-692-8045
	Kinston
	Kinston Medical Specialists
		Peter R. Watson, MD	Ph: 252-559-2200ext.201
	Pinehurst
	FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center
		Clinical Trials Office - FirstHealth Moore Regional Community	Ph: 910-715-2200
	Raleigh
	Rex Cancer Center at Rex Hospital
		Clinical Trials Office - Rex Cancer Center	Ph: 919-784-7209
	Reidsville
	Annie Penn Cancer Center
		Clinical Trials Office - Annie Penn Cancer Center	Ph: 336-621-8374
	Rutherfordton
	Rutherford Hospital
		James D. Bearden, MD	Ph: 864-560-6812
	Washington
	Marion L. Shepard Cancer Center at Beaufort County Hospital
		Jennie R. Crews	Ph: 252-975-4308
	Winston-Salem
	Wake Forest University Comprehensive Cancer Center
		Clinical Trials Office - Wake Forest University Comprehensive	Ph: 336-713-6771
North Dakota
	Bismarck
	Bismarck Cancer Center
		Edward J. Wos, DO	Ph: 701-323-5741
	Medcenter One Hospital Cancer Care Center
		Edward J. Wos, DO	Ph: 701-323-5741
	Mid Dakota Clinic, PC
		Clinical Trials Office - Mid Dakota Clinic, PC	Ph: 701-530-6950
	St. Alexius Medical Center Cancer Center
		Clinical Trials Office - St. Alexius Medical Center Cancer Cen	Ph: 701-530-6950
	Fargo
	CCOP - MeritCare Hospital
		Preston D. Steen, MD	Ph: 701-234-2397
	Dakota Cancer Institute at Dakota Clinic - South University
		Mahendra K. Gupta	Ph: 701-364-8910
	MeritCare Broadway
		Preston D. Steen, MD	Ph: 701-234-2397
	Grand Forks
	Altru Cancer Center at Altru Hospital
		Clinical Trails Office - Altru Cancer Center at Altru Hospital	Ph: 701-780-6520
	Minot
	Trinity CancerCare Center
		Contact Person	Ph: 701-857-3535
Ohio
	Akron
	McDowell Cancer Center at Akron General Medical Center
		Esther H. Rehmus, MD	Ph: 330-344-6505
	Bellefontaine
	Mary Rutan Hospital
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Canton
	Aultman Cancer Center at Aultman Hospital
		Clinical Trials Office - Aultman Cancer Center at Aultman Hosp	Ph: 330-363-6891
	Mercy Cancer Center at Mercy Medical Center
		Mitchell Haut, MD	Ph: 330-453-9993
	Chillicothe
	Adena Regional Medical Center
		Clinical Trials Office - Adena Regional Medical Center	Ph: 877-779-7585
	Cincinnati
	Christ Hospital Cancer Center
		Manish Bhandari	Ph: 513-585-2323
	Cleveland
	MetroHealth Cancer Care Center at MetroHealth Medical Center
		Bruce J. Averbook, MD, FACS	Ph: 216-778-4795
	Columbus
	Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center
		Ohio State University Cancer Clinical Trial Matching Service	Ph: 866-627-7616
			Email: osu@emergingmed.com
	CCOP - Columbus
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Doctors Hospital at Ohio Health
		Clinical Trials Office - Doctors Hospital at Ohio Health	Ph: 614-566-3275
	Grant Medical Center Cancer Care
		Clinical Trials Office - Grant Medical Center Cancer Care	Ph: 614-566-4475
	Mount Carmel Health - West Hospital
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Riverside Methodist Hospital Cancer Care
		Clinical Trials Office - Riverside Methodist Hospital Cancer C	Ph: 614-566-4475
	Dayton
	CCOP - Dayton
		Howard M. Gross, MD	Ph: 937-832-1093
	David L. Rike Cancer Center at Miami Valley Hospital
		Clinical Trials Office - David L. Rike Cancer Center at Miami	Ph: 937-208-2079
	Good Samaritan Hospital
		Howard M. Gross, MD	Ph: 937-832-1093
	Grandview Hospital
		Howard M. Gross, MD	Ph: 937-832-1093
	Samaritan North Cancer Care Center
		Howard M. Gross, MD	Ph: 937-832-1093
	Veterans Affairs Medical Center - Dayton
		Howard M. Gross, MD	Ph: 937-832-1093
	Delaware
	Grady Memorial Hospital
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Findlay
	Blanchard Valley Medical Associates
		Howard M. Gross, MD	Ph: 937-832-1093
	Franklin
	Middletown Regional Hospital
		Howard M. Gross, MD	Ph: 937-832-1093
	Greenville
	Wayne Hospital
		Howard M. Gross, MD	Ph: 937-832-1093
	Kettering
	Charles F. Kettering Memorial Hospital
		Clinical Trials Office - Charles F. Kettering Memorial Hospita	Ph: 937-298-3399 ext. 57556
	Lancaster
	Fairfield Medical Center
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Lima
	St. Rita's Medical Center
		Clinical Trials Office - St. Rita's Medical Center	Ph: 419-226-9617
	Marietta
	Strecker Cancer Center at Marietta Memorial Hospital
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Newark
	Licking Memorial Cancer Care Program at Licking Memorial Hospital
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Springfield
	Community Hospital of Springfield and Clark County
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Mercy Medical Center
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Troy
	UVMC Cancer Care Center at Upper Valley Medical Center
		Clinical Trials Office - UVMC Cancer Care Center at Upper Vall	Ph: 937-440-4842
	Westerville
	Mount Carmel St. Ann's Cancer Center
		J. Philip Kuebler, MD, PhD	Ph: 614-442-3130
	Wilmington
	Clinton Memorial Hospital
		Howard M. Gross, MD	Ph: 937-832-1093
	Wright-Patterson AFB
	United States Air Force Medical Center - Wright-Patterson
		Roger A. Wood	Ph: 937-257-9133
	Xenia
	Ruth G. McMillan Cancer Center at Greene Memorial Hospital
		Howard M. Gross, MD	Ph: 937-832-1093
	Zanesville
	Genesis - Good Samaritan Hospital
		Clinical Trials Office - Genesis - Good Samaritan Hospital	Ph: 740-454-5232
Oklahoma
	Lawton
	Cleo Craig Cancer Research Clinic
		Nadim F. Nimeh, MD	Ph: 580-536-2121ext.113
	Oklahoma City
	Cancer Care Associates - Mercy Campus
		Howard Ozer, MD, PhD	Ph: 405-271-4022
	Oklahoma University Cancer Institute
		Howard Ozer, MD, PhD	Ph: 405-271-4022
	Tulsa
	Natalie Warren Bryant Cancer Center at St. Francis Hospital
		David R. Barnes, MD, FACS	Ph: 423-778-8582
Oregon
	Coos Bay
	Bay Area Hospital
		Bret A. Cook, MD	Ph: 541-267-5151
	Grants Pass
	Three Rivers Community Hospital
		Charles R. Dibb, MD	Ph: 541-774-5853
	Gresham
	Legacy Mount Hood Medical Center
		Clinical Trials Office - Legacy Mount Hood Medical Center	Ph: 503-413-2150
	Medford
	Dubs Cancer Center at Rogue Valley Medical Center
		Charles R. Dibb, MD	Ph: 541-774-5853
	Providence Cancer Center at PMCC
		Charles R. Dibb, MD	Ph: 541-774-5853
	Milwaukie
	Providence Milwaukie Hospital
		Keith S. Lanier, MD	Ph: 503-299-6500
	Portland
	Adventist Medical Center
		Keith S. Lanier, MD	Ph: 503-299-6500
	CCOP - Columbia River Oncology Program
		Keith S. Lanier, MD	Ph: 503-299-6500
	Kaiser Permanente Health Care - Portland
		Nagendra Tirumali, MD	Ph: 503-331-6500
	Knight Cancer Institute at Oregon Health and Science University
		Clinical Trials Office - Knight Cancer Institute at Oregon Hea	Ph: 503-494-1080
			Email: trials@ohsu.edu
	Legacy Emanuel Hospital and Health Center and Children's Hospital
		Clinical Trials Office - Legacy Emanuel Hospital and Health Ce	Ph: 503-413-8199
	Legacy Good Samaritan Hospital & Comprehensive Cancer Center
		Clinical Trials Office - Legacy Good Samaritan Hospital & Com	Ph: 503-413-1742
	Northwest Cancer Specialists at Rose Quarter Cancer Center
		Kasra Karamlou	Ph: 503-228-6509
	Providence Cancer Center at Providence Portland Medical Center
		Clinical Trials Office - Providence Cancer Center at Providenc	Ph: 503-215-6412
	Providence St. Vincent Medical Center
		Clinical Trials Office - Providence St. Vincent Medical Center	Ph: 503-215-6412
	Salem
	Salem Hospital Regional Cancer Care Services
		Clinical Trials Office - Salem Hospital Regional Cancer Care S	Ph: 503-561-2618
	Tualatin
	Legacy Meridian Park Hospital
		Clinical Trials Office - Legacy Meridian Park Hospital	Ph: 503-413-1742
Pennsylvania
	Abington
	Rosenfeld Cancer Center at Abington Memorial Hospital
		Clinical Trials Office - Rosenfeld Cancer Center at Abington M	Ph: 215-481-2402
	Allentown
	Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
		Eliot L. Friedman, MD	Ph: 610-402-0512
	Bethlehem
	St. Luke's Cancer Network at St. Luke's Hospital
		Sanjiv S. Agarwala, MD	Ph: 610-954-2145
	Bryn Mawr
	Bryn Mawr Hospital
		Clinical Trials Office - Bryn Mawr Hospital	Ph: 610-645-2680
	Danville
	Geisinger Cancer Institute at Geisinger Health
		Clinical Trials Office - Geisinger Cancer Institute	Ph: 570-271-5251
	Darby
	Mercy Fitzgerald Hospital
		Clinical Trials Office - Mercy Fitzgerald Hospital	Ph: 610-237-4982
	Doylestown
	Doylestown Hospital Cancer Center
		Mitchell Alden, DO	Ph: 215-345-8444
	Drexel Hill
	Delaware County Regional Cancer Center at Delaware County Memorial Hospital
		Marc Rovito, MD	Ph: 610-622-3818
	Dubois
	Oncology Hematology Associates of Northern Pennsylvania, PC at Hahne Regional Cancer Center
		Carmine Marchioli, MD	Ph: 814-375-3535
	East Stroudsburg
	Dale and Frances Hughes Cancer Center at Pocono Medical Center
		Ronald I. Cantor	Ph: 570-476-3488
	Ephrata
	Ephrata Cancer Center at Ephrata Community Hospital
		Ronald I. Cantor	Ph: 717-738-4070
	Erie
	Regional Cancer Center - Erie
		Amer S. Khouri	Ph: 814-838-9000
	Saint Vincent Health Center
		Amer S. Khouri	Ph: 814-452-5000
	Harrisburg
	PinnacleHealth Regional Cancer Center at Polyclinic Hospital
		Oncology Clinical Trial Coordinator	Ph: 717-782-4750
	Hazleton
	Geisinger Hazleton Cancer Center
		Albert M. Bernath, MD	Ph: 570-214-9290
	Hershey
	Penn State Cancer Institute at M