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Last Modified: 11/19/2009     First Published: 9/16/2005  
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Phase III Randomized Study of Oxaliplatin, Leucovorin Calcium, and Fluorouracil With Versus Without Bevacizumab in Patients With Resected Stage II Colon Cancer and at High Risk for Recurrence Based on Molecular Markers

Alternate Title
Basic Trial Information
Objectives
Entry Criteria
Expected Enrollment
Outcomes
Outline
Trial Contact Information
Related Information
Registry Information

Alternate Title

Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentActive18 and overNCIECOG-E5202
E5202, NCT00217737

Special Category: CTSU trial, NCI - CMS pilot project trial, NCI Web site featured trial

Objectives

Primary

  1. Compare the 3-year disease-free survival of patients with resected stage II colon cancer at high risk for recurrence treated with oxaliplatin, leucovorin calcium, and fluorouracil with vs without bevacizumab.

Secondary

  1. Compare the overall survival of patients treated with these regimens.
  2. Compare the toxicity profiles of these regimens in these patients.
  3. Correlate tumor biologic characteristics with survival of patients treated with these regimens.

Entry Criteria

Disease Characteristics:

  • Histologically confirmed adenocarcinoma of the colon
    • Stage II disease (T3-4, N0, M0)
      • At least 8 lymph nodes must have been evaluated

  • Meets 1 of the following criteria:
    • High risk for microsatellite instability (MSI) and loss of heterozygosity (LOH) at chromosome 18q
      • Microsatellite stable (MSS) with 18q LOH
      • MSI-low grade (MSI-L) with 18q LOH
    • Low risk for MSI and 18q LOH
      • MSS with retention of 18q alleles
      • MSI-L with retention of 18q alleles
      • MSI-high grade (MSI-H) with retention of 18q alleles
      • MSI-H without retention of 18q alleles
      • MSI-H with 18q status uninformative

  • Distal extent of tumor must be ≥ 12 cm from the anal verge by endoscopy or surgical examination
    • If tumor is located beyond sigmoid colon and centimeter distance is unavailable, include anatomic region of the colon (e.g., right colon, transverse colon, hepatic flexure, descending colon, or cecum)

  • Has undergone surgical resection of the tumor between the past 28-60 days
    • Must have had a complete resection (R0 resection)

  • No history of isolated, distant, or noncontiguous intra-abdominal metastases

  • Patients with synchronous tumors or appendiceal tumors are ineligible

  • Hereditary non-polyposis colorectal cancer allowed

  • Paraffin-embedded tumor specimen (one with normal mucosa and one from the resection tumor) available

Prior/Concurrent Therapy:

Biologic therapy

  • Not specified

Chemotherapy

  • Not specified

Endocrine therapy

  • Not specified

Radiotherapy

  • No prior radiotherapy for this cancer

Surgery

  • See Disease Characteristics
  • More than 28 days since prior major surgery or open biopsy*
  • More than 7 days since prior core biopsy or other minor procedure except placement of a vascular access device*

 [Note: *For patients with high-risk disease only]

Other

  • No prior systemic therapy for this cancer

 [Note: *For patients with high-risk disease only]

Patient Characteristics:

Age

  • 18 and over

Performance status

  • ECOG 0-2

Life expectancy

  • Not specified

Hematopoietic

  • Absolute granulocyte count ≥ 1,500/mm3*
  • Platelet count ≥ 100,000/mm3*
  • No significant bleeding unrelated to tumor within the past 6 months*

 [Note: *For patients with high-risk disease only]

Hepatic

  • Bilirubin normal (unless due to Gilbert's disease or similar syndrome)*
  • Alkaline phosphatase (AP) < 2.5 times upper limit of normal (ULN)*
  • AST < 1.5 times ULN*
  • PT INR > 1.5* allowed provided the following criteria are met:
    • Patient is on full-dose anticoagulants
    • INR in range (usually 2-3) on a stable dose of warfarin or low molecular weight heparin
    • No active bleeding or pathological condition associated with a high risk of bleeding unrelated to primary colon tumor
  • No systemic hepatic disease*

 [Note: *For patients with high-risk disease only]

Renal

  • Creatinine ≤ 1.5 times ULN*
  • Urine protein:creatinine ratio < 1.0*

    OR

  • Urine protein < 1 gm on 24-hour urine collection*
  • No systemic renal disease*

 [Note: *For patients with high-risk disease only]

Cardiovascular

  • History of hypertension allowed provided blood pressure < 150/90 mm Hg while on a stable regimen of anti-hypertensive therapy*
  • No New York Heart Association class III or IV cardiac disease*
  • No symptomatic arrhythmia*
  • No history of transient ischemic attack*
  • No history of cerebrovascular accident*
  • No symptomatic peripheral vascular disease*
  • No arterial thromboembolic events within the past 12 months*
  • No unstable angina within the past 12 months*
  • No myocardial infarction within the past 12 months*
  • No other systemic cardiovascular disease*

 [Note: *For patients with high-risk disease only]

Other

  • Not pregnant or nursing*
  • Negative pregnancy test*
  • Fertile patients must use effective contraception during and for 3 months after completion of study treatment*
  • No active gastroduodenal ulcer by endoscopy*
  • No complete obstruction or perforation of the bowel
  • No history of inflammatory bowel disease
  • No prior or concurrent malignancy except for nonmelanoma skin cancer, carcinoma in situ of the cervix, breast cancer in situ, treated non-pelvic cancer from which the patient has been disease-free for > 5 years, or history of breast cancer (without evidence of disease) and remain on hormonal therapy for > 5 years
  • No other nonmalignant systemic disease that would preclude study compliance*
  • No psychiatric or addictive disorder or other condition that would preclude study participation*
  • No serious or non-healing wound, skin ulcer, or bone fracture*
  • No peripheral neuropathy ≥ grade 2*
  • No significant traumatic injury within the past 4 weeks*
  • No known allergy to platinum compounds

 [Note: *For patients with high-risk disease only]

Expected Enrollment

3610

A total of 3,610 patients will be accrued for this study within 5.8 years.

Outcomes

Primary Outcome(s)

Disease-free survival at 3 years

Secondary Outcome(s)

Overall survival
Toxicity
Correlation of tumor biologic characteristics with survival

Outline

This is a randomized study. Patients are stratified according to disease stage (IIA vs IIB) and microsatellite stability (MSS) (stable vs low-grade instability [MSI-L]). Patients with disease that is at high risk for microsatellite instability (MSI) and loss of heterozygosity (LOH) at chromosome 18q are randomized to 1 of 2 treatment arms (arms I and II). Patients with disease that is at low risk for MSI and 18q LOH are assigned to arm III.

  • Arm I: Patients receive oxaliplatin IV over 2 hours and leucovorin calcium IV over 2 hours on day 1. Patients also receive fluorouracil IV bolus followed by fluorouracil IV continuously over 46 hours beginning on day 1. Treatment repeats every 2 weeks for 12 courses in the absence of disease progression or unacceptable toxicity.

  • Arm II: Patients receive oxaliplatin, leucovorin calcium, and fluorouracil as in arm I and bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 2 weeks for 12 courses in the absence of disease progression or unacceptable toxicity. Patients then receive bevacizumab alone for 12 additional courses in the absence of disease progression or unacceptable toxicity.

  • Arm III: Patients undergo observation only.

Patients are followed every 3 months for 1-2 years, every 6 months for 3 years, and then annually for up to 10 years from study entry.

Trial Contact Information

Trial Lead Organizations

Eastern Cooperative Oncology Group

Al Benson, MD, FACP, Protocol chair
Ph: 312-695-6180
Peter O'Dwyer, MD, BCh, Protocol co-chair
Ph: 215-662-7606
Email: peter.odwyer@uphs.upenn.edu

Trial Sites

U.S.A.
Alabama
  Anniston
 Regional Medical Center
 Pramod Vadlamani
Ph: 256-235-5877
  Birmingham
 UAB Comprehensive Cancer Center
 Clinical Trials Office - UAB Comprehensive Cancer Center
Ph: 205-934-0309
  Huntsville
 Clearview Cancer Institute
 Clinical Trials Office - Clearview Cancer Institute
Ph: 256-705-4224
  Mobile
 Providence Cancer Center at Providence Hospital
 Thaddeus Beeker
Ph: 251-633-1890
Alaska
  Anchorage
 Providence Cancer Center
 Clinical Trials Office - Providence Cancer Center
Ph: 907-261-3109
Arizona
  Scottsdale
 Mayo Clinic Scottsdale
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Tucson
 Arizona Cancer Center at University of Arizona Health Sciences Center
 Clinical Trials Office - Arizona Cancer Center at University of Arizona Health Sciences Center
Ph: 520-626-9008
Arkansas
  Ft. Smith
 Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
 John Wells, MD
Ph: 479-484-4700
California
  Berkeley
 Alta Bates Summit Comprehensive Cancer Center
 Clinical Trials Office - Alta Bates Summit Comprehensive Cancer Center
Ph: 510-204-3428
  Burlingame
 Peninsula Medical Center
 David Irwin, MD
Ph: 510-204-1591
  Concord
 Cancer Care Center at John Muir Health - Concord Campus
 Clinical Trials Office - Cancer Care Center at John Muir Health - Concord Campus
Ph: 925-674-2580
  Fremont
 Washington Township Hospital
 Byron Wilson, MD
Ph: 510-888-0657
  Fullerton
 Virginia K. Crosson Cancer Center at St. Jude Medical Center
 Clinical Trials Office - Virginia K. Crosson Cancer Center
Ph: 714-446-5642
  Glendale
 Glendale Memorial Hospital Comprehensive Cancer Center
 Clinical Trials Office - Glendale Memorial Hospital Comprehensive Cancer Center
Ph: 818-409-7653
  Greenbrae
 California Cancer Care, Incorporated - Greenbrae
 Peter Eisenberg, MD
Ph: 415-925-5000
 Marin Cancer Institute at Marin General Hospital
 David Irwin, MD
Ph: 510-204-1591
 Sutter Health - Western Division Cancer Research Group
 David Irwin, MD
Ph: 510-204-1591
  Loma Linda
 Loma Linda University Cancer Institute at Loma Linda University Medical Center
 Clinical Trials Office - Loma Linda University Cancer Institute
Ph: 909-558-3375
  Los Angeles
 USC/Norris Comprehensive Cancer Center and Hospital
 Clinical Trials Office - USC/Norris Comprehensive Cancer Center and Hospital
Ph: 323-865-0451
  Modesto
 Memorial Medical Center
 Clinical Trials Office - Memorial Medical Center
Ph: 209-572-7116
  Mountain View
 Camino Medical Group - Treatment Center
 Peter Yu, MD
Ph: 408-524-5814
  Orange
 St. Joseph Hospital Regional Cancer Center - Orange
 Timothy Byun
Ph: 714-771-8999
  Palm Springs
 Desert Regional Medical Center Comprehensive Cancer Center
 Clinical Trials Office - Desert Regional Medical Center Comprehensive Cancer Center
Ph: 760-416-4730
  Palo Alto
 Palo Alto Medical Foundation
 Peter Yu, MD
Ph: 408-524-5814
  Rancho Mirage
 Lucy Curci Cancer Center at Eisenhower Memorial Hospital and Medical Center
 Murthy Andavolu
Ph: 760-674-3600
  Roseville
 Sutter Cancer Center at Roseville Medical Center
 Clinical Trials Office - Sutter Cancer Center
Ph: 916-454-6595
  Sacramento
 Sutter Cancer Center
 Clinical Trial Office - Sutter Cancer Center
Ph: 916-454-6595
  San Diego
 Kaiser Permanente Medical Office -Vandever Medical Office
 Jonathan Polikoff, MD
Ph: 619-528-5888
 Sharp Memorial Hospital Cancer Center
 Clinical Trials Office - Sharp Memorial Hospital Cancer Center
Ph: 858-939-5015
  San Francisco
 California Pacific Medical Center - California Campus
 David Irwin, MD
Ph: 510-204-1591
 San Francisco General Hospital Medical Center
 Alan Venook, MD
Ph: 415-353-7065
 UCSF Helen Diller Family Comprehensive Cancer Center
 Clinical Trials Office - UCSF Helen Diller Family Comprehensive Cancer Center
Ph: 877-827-3222
  Vallejo
 Sutter Solano Medical Center
 David Irwin, MD
Ph: 510-204-1591
  Walnut Creek
 John Muir/Mt. Diablo Comprehensive Cancer Center
 Clinical Trials Office - John Muir/Mt. Diablo Comprehensive Cancer Center
Ph: 925-941-4246
Colorado
  Aurora
 University of Colorado Cancer Center at UC Health Sciences Center
 Clinical Trials Office - University of Colorado Cancer Center
Ph: 720-848-0650
  Denver
 Denver Health Medical Center
 Wells Messersmith, MD
Ph: 410-502-6873
 Veterans Affairs Medical Center - Denver
 Wells Messersmith, MD
Ph: 410-502-6873
  Edwards
 Shaw Regional Cancer Center
 Wells Messersmith, MD
Ph: 410-502-6873
  Fort Collins
 Front Range Cancer Specialists
 Robert Marschke, Jr.
Ph: 970-212-7600
 Poudre Valley Hospital
 Clinical Trials Office - Poudre Valley Hospital
Ph: 970-495-8226
  Montrose
 Montrose Memorial Hospital Cancer Center
 Clinical Trials Office - Montrose Memorial Hospital Cancer Center
Ph: 670-240-7267
Connecticut
  Bridgeport
 Bridgeport Hospital
 Clinical Trials Office - Bridgeport Hospital
Ph: 203-384-4869
  Danbury
 Praxair Cancer Center at Danbury Hospital
 Robert Kloss, MD
Ph: 203-797-7029
  Hartford
 Helen and Harry Gray Cancer Center at Hartford Hospital
 Clinical Trials Office - Helen and Harry Gray Cancer Center
Ph: 860-545-5363
  Norwich
 Eastern Connecticut Hematology and Oncology Associates
 Dennis Slater, MD
Ph: 860-886-8362
  Stamford
 Carl and Dorothy Bennett Cancer Center at Stamford Hospital
 Clinical Trials Office - Carl and Dorothy Bennett Cancer Center
Ph: 203-323-8944
Delaware
  Lewes
 Tunnell Cancer Center at Beebe Medical Center
 Clinical Trials Office - Tunnell Cancer Center
Ph: 302-645-3171
  Newark
 CCOP - Christiana Care Health Services
 Clinical Trial Office - CCOP - Christiana Care Health Services
Ph: 302-733-6227
Florida
  Boca Raton
 Eugene M. and Christine E. Lynn Cancer Institute at Boca Raton Community Hospital - Main Campus
 Clinical Trials Office - Eugene M. and Christine E. Lynn Cancer Institute
Ph: 561-955-4800
  Fort Lauderdale
 Broward General Medical Center Cancer Center
 Clinical Trials Office - Broward General Medical Center Cancer Center
Ph: 954-355-5346
  Jacksonville
 Baptist Cancer Institute - Jacksonville
 Clinical Trials Office - Baptist Cancer Institute - Jacksonville
Ph: 904-202-7051
 Mayo Clinic - Jacksonville
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Leesburg
 Cancer Centers of Central Florida, PA
 Glenn Mills, MD
Ph: 318-813-1440
  Orange Park
 Integrated Community Oncology Network - Orange Park
 Linda Struhar-Sylvester, MD, FACP
Ph: 904-272-3139
  Weston
 Cleveland Clinic Florida - Weston
 Clinical Trials Office - Cleveland Clinic Florida - Weston
Ph: 954-659-5705
Georgia
  Athens
 Northeast Georgia Cancer Care, LLC - Medical Oncology
 Clinical Trials Office - Northeast Georgia Cancer Care, LLC
Ph: 706-353-5006
  Atlanta
 CCOP - Atlanta Regional
 Thomas Seay, MD, PhD
Ph: 404-851-2340
 Northside Hospital Cancer Center
 Clinical Trials Office - Northside Hospital Cancer Center
Ph: 404-303-3355
 Piedmont Hospital
 Thomas Seay, MD, PhD
Ph: 404-851-2340
 Saint Joseph's Hospital of Atlanta
 Clinical Trials Office - Saint Joseph's Hospital of Atlanta
Ph: 404-851-7115
  Augusta
 Augusta Oncology Associates - Walton Way
 Mark Keaton, MD
Ph: 706-821-2944
 MBCCOP - Medical College of Georgia Cancer Center
 Anand Jillella, MD
Ph: 706-721-2505
  Austell
 WellStar Cobb Hospital
 Clinical Trials Office - WellStar Cobb Hospital
Ph: 770-793-5980
  Decatur
 Charles B. Eberhart Cancer Center at DeKalb Medical Center
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Gainesville
 Northeast Georgia Medical Center
 Richard LoCicero, MD
Ph: 770-297-5700
  Lawrenceville
 Gwinnett Medical Center
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Marietta
 Kennestone Cancer Center at Wellstar Kennestone Hospital
 Clinical Trials Office - Kennestone Cancer Center
Ph: 770-793-5980
  Riverdale
 Southern Regional Medical Center
 Clinical Trials Office - Southern Regional Medical Center
Ph: 770-991-8611
  Rome
 Harbin Clinic Cancer Center - Medical Oncology
 Thomas Seay, MD, PhD
Ph: 404-851-2340
  Savannah
 Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
 Clinical Trials Office - Curtis and Elizabeth Anderson Cancer Institute
Ph: 912-350-8568
 Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
 Mark Taylor, MD
Ph: 912-354-6187
Hawaii
  Honolulu
 Tripler Army Medical Center
 Jeffrey Berenberg, MD
Ph: 808-433-4089
Illinois
  Alton
 Saint Anthony's Hospital at Saint Anthony's Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Bloomington
 St. Joseph Medical Center
 John Kugler, MD
Ph: 309-243-3605
  Canton
 Graham Hospital
 John Kugler, MD
Ph: 309-243-3605
  Carthage
 Memorial Hospital
 John Kugler, MD
Ph: 309-243-3605
  Chicago
 Creticos Cancer Center at Advocate Illinois Masonic Medical Center
 Clinical Trials Office - Creticos Cancer Center at Advocate Illinois Masonic Medical Center
Ph: 773-296-5360
 Hematology and Oncology Associates
 Clinical Trails Office - Hematology and Oncology Associates
Ph: 312-695-1301
 John H. Stroger, Jr. Hospital of Cook County
 Michael Mullane
Ph: 312-864-3200
 Robert H. Lurie Comprehensive Cancer Center at Northwestern University
 Clinical Trials Office - Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Ph: 312-695-1301
 Email: cancer@northwestern.edu
 University of Chicago Cancer Research Center
 Clinical Trials Office - University of Chicago Cancer Research Center
Ph: 773-834-7424
  Decatur
 Decatur Memorial Hospital Cancer Care Institute
 Clinical Trials Office - Decatur Memorial Hospital Cancer Care Institute
Ph: 217-876-6601
  Elgin
 Sherman Hospital
 James Wade, MD
Ph: 217-876-6617
  Elmhurst
 Elmhurst Memorial Hospital
 Robert Eisner
Ph: 630-833-1400
  Eureka
 Eureka Community Hospital
 John Kugler, MD
Ph: 309-243-3605
  Evanston
 Evanston Hospital
 Clinical Trials Office - Evanston Hospital
Ph: 847-570-1381
  Galesburg
 Galesburg Clinic, PC
 John Kugler, MD
Ph: 309-243-3605
 Galesburg Cottage Hospital
 John Kugler, MD
Ph: 309-243-3605
  Harvey
 Ingalls Cancer Care Center at Ingalls Memorial Hospital
 Clinical Trials Office - Ingalls Cancer Care Center at Ingalls Memorial Hospital
Ph: 708-915-6747
  Havana
 Mason District Hospital
 John Kugler, MD
Ph: 309-243-3605
  Joliet
 Midwest Center for Hematology/Oncology
 Al Benson, MD, FACP
Ph: 312-695-6180
  Kankakee
 Provena St. Mary's Regional Cancer Center - Kankakee
 Riaz Elahi, MD
Ph: 708-873-4500
  La Grange
 La Grange Memorial Hospital
 Clinical Trials Office - La Grange Memorial Hospital
Ph: 630-856-7526
  Libertyville
 North Shore Oncology and Hematology Associates, Limited - Libertyville
 Al Benson, MD, FACP
Ph: 312-695-6180
  Macomb
 McDonough District Hospital
 John Kugler, MD
Ph: 309-243-3605
  Maywood
 Cardinal Bernardin Cancer Center at Loyola University Medical Center
 Clinical Trials Office - Cardinal Bernardin Cancer Center
Ph: 708-226-4357
  Monmouth
 OSF Holy Family Medical Center
 John Kugler, MD
Ph: 309-243-3605
  Mt. Vernon
 Good Samaritan Regional Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Naperville
 Edward Hospital Cancer Center
 Clinical Trials Office - Edward Hospital Cancer Center
Ph: 630-646-6075
 La Grange Oncology Associates - Geneva
 Al Benson, MD, FACP
Ph: 312-695-6180
  Niles
 Cancer Care and Hematology Specialists of Chicagoland - Niles
 Al Benson, MD, FACP
Ph: 312-695-6180
  Normal
 BroMenn Regional Medical Center
 John Kugler, MD
Ph: 309-243-3605
 Community Cancer Center
 John Kugler, MD
Ph: 309-243-3605
  Ottawa
 Community Hospital of Ottawa
 John Kugler, MD
Ph: 309-243-3605
 Oncology Hematology Associates of Central Illinois, PC - Ottawa
 John Kugler, MD
Ph: 309-243-3605
  Pekin
 Cancer Treatment Center at Pekin Hospital
 John Kugler, MD
Ph: 309-243-3605
  Peoria
 CCOP - Illinois Oncology Research Association
 John Kugler, MD
Ph: 309-243-3605
 Methodist Medical Center of Illinois
 Clinical Trials Office - Methodist Medical Center of Illinois
Ph: 309-243-3000
 Oncology Hematology Associates of Central Illinois, PC - Peoria
 John Kugler, MD
Ph: 309-243-3605
 OSF St. Francis Medical Center
 John Kugler, MD
Ph: 309-243-3605
 Proctor Hospital
 John Kugler, MD
Ph: 309-243-3605
  Peru
 Illinois Valley Community Hospital
 John Kugler, MD
Ph: 309-243-3605
  Rockford
 Center for Cancer Care at OSF Saint Anthony Medical Center
 Clinical Trials Office - Center for Cancer Care at OSF Saint Anthony Medical Center
Ph: 815-227-2633
 Swedish-American Regional Cancer Center
 Clinical Trials Office - Swedish-American Regional Cancer Center
Ph: 815-489-4413
  Skokie
 Hematology Oncology Associates - Skokie
 Al Benson, MD, FACP
Ph: 312-695-6180
  Spring Valley
 St. Margaret's Hospital
 John Kugler, MD
Ph: 309-243-3605
  Springfield
 Regional Cancer Center at Memorial Medical Center
 Clinical Trials Office - Regional Cancer Center at Memorial Medical Center
Ph: 217-788-4233
  Winfield
 Central Dupage Cancer Center
 Kenneth Micetich, MD
Ph: 708-327-3144
Indiana
  Beech Grove
 St. Francis Hospital and Health Centers - Beech Grove Campus
 Howard Gross, MD
Ph: 937-832-1093
  Elkhart
 Elkhart General Hospital
 Bilal Ansari, MD
Ph: 269-983-8260
  Fort Wayne
 Fort Wayne Medical Oncology and Hematology
 Sreenivasa Nattam, MD
Ph: 260-484-8830
  Kokomo
 Howard Community Hospital
 Bilal Ansari, MD
Ph: 269-983-8260
  La Porte
 Center for Cancer Therapy at LaPorte Hospital and Health Services
 Bilal Ansari, MD
Ph: 269-983-8260
  Lafayette
 Clarian Arnett Cancer Care
 Thomas Jones, MD
Ph: 765-448-7500
  Richmond
 Reid Hospital & Health Care Services
 Howard Gross, MD
Ph: 937-832-1093
  South Bend
 CCOP - Northern Indiana CR Consortium
 Bilal Ansari, MD
Ph: 269-983-8260
 Memorial Hospital of South Bend
 Clinical Trials Office - Memorial Hospital of South Bend
Ph: 800-284-7370
 Saint Joseph Regional Medical Center
 Bilal Ansari, MD
Ph: 269-983-8260
 South Bend Clinic
 Bilal Ansari, MD
Ph: 269-983-8260
Iowa
  Ames
 McFarland Clinic, PC
 Clinical Trials Office - McFarland Clinic, PC
Ph: 515-239-2621
  Cedar Rapids
 Cedar Rapids Oncology Associates
 Clinical Trials Office - Cedar Rapids Oncology Associates
Ph: 319-363-2690
 Mercy Regional Cancer Center at Mercy Medical Center
 Martin Wiesenfeld, MD
Ph: 319-363-8303
  Clive
 Medical Oncology and Hematology Associates - West Des Moines
 Robert Behrens
Ph: 515-875-9713
  Davenport
 Genesis Regional Cancer Center at Genesis Medical Center
 George Kovach, MD
Ph: 563-421-1960
  Des Moines
 CCOP - Iowa Oncology Research Association
 Robert Behrens
Ph: 515-244-7586
888-244-6061
 John Stoddard Cancer Center at Iowa Lutheran Hospital
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Lutheran Hospital
Ph: 515-241-8704
 John Stoddard Cancer Center at Iowa Methodist Medical Center
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Methodist Medical Center
Ph: 515-241-6727
 Medical Oncology and Hematology Associates at John Stoddard Cancer Center
 Robert Behrens
Ph: 515-282-2921
 Medical Oncology and Hematology Associates at Mercy Cancer Center
 Robert Behrens
Ph: 515-643-8740
 Mercy Cancer Center at Mercy Medical Center - Des Moines
 Robert Behrens
Ph: 515-643-8206
888-221-4849
  Iowa City
 Holden Comprehensive Cancer Center at University of Iowa
 Cancer Information Service
Ph: 800-237-1225
  Ottumwa
 McCreery Cancer Center at Ottumwa Regional
 Robert Behrens
Ph: 641-684-2946
Kansas
  Chanute
 Cancer Center of Kansas, PA - Chanute
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Dodge City
 Cancer Center of Kansas, PA - Dodge City
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  El Dorado
 Cancer Center of Kansas, PA - El Dorado
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Fort Scott
 Cancer Center of Kansas - Fort Scott
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Hays
 Hays Medical Center
 Peter VanVeldhuizen, MD
Ph: 816-861-4700ext.56775
  Hutchinson
 Hutchinson Hospital Corporation
 Peter VanVeldhuizen, MD
Ph: 816-861-4700ext.56775
  Independence
 Cancer Center of Kansas-Independence
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Kansas City
 Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
 Clinical Trials Office - Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
Ph: 913-588-4709
  Kingman
 Cancer Center of Kansas, PA - Kingman
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Lawrence
 Lawrence Memorial Hospital
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Liberal
 Southwest Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Newton
 Cancer Center of Kansas, PA - Newton
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Olathe
 Olathe Cancer Center
 Peter VanVeldhuizen, MD
Ph: 816-861-4700ext.56775
  Parsons
 Cancer Center of Kansas, PA - Parsons
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Pittsburg
 Mount Carmel Regional Cancer Center
 Boban Mathew, MD
Ph: 620-235-7900
  Pratt
 Cancer Center of Kansas, PA - Pratt
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Salina
 Cancer Center of Kansas, PA - Salina
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Topeka
 Cotton-O'Neil Cancer Center
 Clinical Trials Office - Cotton-O'Neil Cancer Center
Ph: 785-270-4963
 St. Francis Comprehensive Cancer Center
 Peter VanVeldhuizen, MD
Ph: 816-861-4700ext.56775
  Wellington
 Cancer Center of Kansas, PA - Wellington
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Wichita
 Associates in Womens Health, PA - North Review
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Medical Arts Tower
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 CCOP - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Via Christi Cancer Center at Via Christi Regional Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Winfield
 Cancer Center of Kansas, PA - Winfield
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
Kentucky
  Ashland
 Cancer Care at Our Lady of Bellefonte Hospital
 Clinical Trials Office - Cancer Care at Our Lady of Bellefonte Hospital
Ph: 606-833-3253
  Lexington
 Central Baptist Hospital
 Clinical Trials Office - Central Baptist Hospital
Ph: 859-260-6425
  Louisville
 James Graham Brown Cancer Center at University of Louisville
 Vivek Sharma
Ph: 502-562-4158
866-530-5516
Louisiana
  Baton Rouge
 Mary Bird Perkins Cancer Center - Baton Rouge
 Robert Veith
Ph: 225-767-0847
 Ochsner Health Center - Bluebonnet
 Jyotsna Fuloria
Ph: 225-761-5200
  Houma
 Terrebonne General Medical Center
 Jyotsna Fuloria
Ph: 985-850-6300
  Mansfield
 DeSoto Regional Hospital
 Glenn Mills, MD
Ph: 318-813-1440
  Monroe
 Louisiana State University Health Sciences Center - Monroe
 Glenn Mills, MD
Ph: 318-813-1440
  New Orleans
 CCOP - Ochsner
 Jyotsna Fuloria
Ph: 504-842-3910
 MBCCOP - LSU Health Sciences Center
 Robert Veith
Ph: 504-568-5151
 Medical Center of Louisiana - New Orleans
 Robert Veith
Ph: 504-903-2311
 Ochsner Cancer Institute at Ochsner Clinic Foundation
 Jyotsna Fuloria
Ph: 504-842-4360
888-624-7637
  Shreveport
 Feist-Weiller Cancer Center at Louisiana State University Health Sciences
 Clinical Trials Office - Feist-Weiller Cancer Center at Louisiana State University Health Sciences
Ph: 318-813-1412
 Highland Clinic
 Glenn Mills, MD
Ph: 318-813-1440
Maine
  Scarborough
 Maine Center for Cancer Medicine and Blood Disorders - Scarborough
 David Benton
Ph: 207-885-7600
  York
 York Hospital's Oncology Treatment Center
 Jonathan Eneman
Ph: 207-351-3777
Maryland
  Baltimore
 Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
 Clinical Trials Office - Harry & Jeanette Weinberg Cancer Institute at Franklin Square Hospital Center
Ph: 443-777-7364
 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
 Clinical Trials Office - Sidney Kimmel Comprehensive Cancer Center at John Hopkins
Ph: 410-955-8804
 Email: jhcccro@jhmi.edu
 St. Agnes Hospital Cancer Center
 Carole Miller, MD
Ph: 410-368-3414
  Easton
 Shore Regional Cancer Center at Memorial Hospital - Easton
 Mary DeShields, MD
Ph: 410-819-3332
  Elkton MD
 Union Hospital Cancer Program at Union Hospital
 Stephen Grubbs, MD
Ph: 302-366-1200
  Frederick
 Frederick Memorial Hospital Regional Cancer Therapy Center
 Paul Rausch, MD
Ph: 301-662-8477
  Hagerstown
 John R. Marsh Cancer Center at Washington County Hospital
 Michael McCormack
Ph: 301-665-4650
  Towson
 Cancer Institute at St. Joseph Medical Center
 Richard Schraeder, Jr.
Ph: 410-337-1000
Massachusetts
  Brighton
 Caritas St. Elizabeth's Medical Center
 Rekha Parameswaran
Ph: 617-789-3000
  Concord
 Commonwealth Hematology-Oncology, PC - Concord
 Susan Sajer, MD
Ph: 978-287-3436
  Lawrence
 Commonwealth Hematology-Oncology, PC - Lawrence
 Susan Sajer, MD
Ph: 978-287-3436
  Quincy
 Commonwealth Hematology-Oncology, PC - Quincy
 Susan Sajer, MD
Ph: 978-287-3436
  Stoneham
 Commonwealth Hematology-Oncology, PC - Stoneham
 Susan Sajer, MD
Ph: 978-287-3436
  Weymouth
 Commonwealth Hematology-Oncology, PC - Weymouth
 Susan Sajer, MD
Ph: 978-287-3436
  Worcester
 Commonwealth Hematology-Oncology, PC - Worcester
 Susan Sajer, MD
Ph: 978-287-3436
 UMASS Memorial Cancer Center - University Campus
 Bilal Piperdi, MD
Ph: 508-856-3933
Michigan
  Adrian
 Hickman Cancer Center at Bixby Medical Center
 Clinical Trials Office - Hickman Cancer Center at Bixby Medical Center
Ph: 517-265-0116
  Battle Creek
 Battle Creek Health System Cancer Care Center
 Martin Bury
Ph: 616-966-8000
  Bay City
 Bay Regional Medical Center
 Clinical Trials Office - Bay Regional Medical Center
Ph: 989-667-6257
  Big Rapids
 Mecosta County Medical Center
 Martin Bury
Ph: 231-796-8691
  Escanaba
 Green Bay Oncology, Limited - Escanaba
 Gerald Bayer, MD
Ph: 920-432-6049
  Flint
 Great Lakes Cancer Institute at McLaren Regional Medical Center
 Clinical Trials Office - Great Lakes Cancer Institute at McLaren Regional Medical Center
Ph: 810-342-4071
  Grand Rapids
 Butterworth Hospital at Spectrum Health
 Martin Bury
Ph: 616-391-2799
 CCOP - Grand Rapids
 Martin Bury
Ph: 616-391-1230
 Lacks Cancer Center at Saint Mary's Health Care
 Martin Bury
Ph: 616-752-5222
  Iron Mountain
 Dickinson County Healthcare System
 Gerald Bayer, MD
Ph: 920-432-6049
  Kalamazoo
 Borgess Medical Center
 Raymond Lord, MD
Ph: 269-373-7458
 Bronson Methodist Hospital
 Raymond Lord, MD
Ph: 269-373-7458
 West Michigan Cancer Center
 Clinical Trials Office - West Michigan Cancer Center
Ph: 269-373-7458
  Lambertville
 Haematology-Oncology Associates of Ohio and Michigan, PC
 Paul Schaefer, MD
Ph: 419-479-5605
  Lansing
 Breslin Cancer Center at Ingham Regional Medical Center
 Clinical Trials Office - Breslin Cancer Center at Ingham Regional Medical Center
Ph: 517-334-2765
  Lapeer
 Lapeer Regional Hospital
 Barbara Conley, MD
Ph: 517-334-2765
  Monroe
 Community Cancer Center of Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
 Mercy Memorial Hospital - Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
  Muskegon
 Mercy General Health Partners
 Martin Bury
Ph: 231-672-2000
  Petoskey
 Northern Michigan Hospital
 Justin Call
Ph: 231-487-4000
800-248-6777
  Royal Oak
 William Beaumont Hospital - Royal Oak Campus
 Clinical Trials Office - William Beaumont Hospital - Royal Oak Campus
Ph: 248-551-7695
  Saint Joseph
 Oncology Care Associates, PLLC
 Eric Lester, MD
Ph: 269-985-0029
  Southfield
 Providence Cancer Institute at Providence Hospital - Southfield Campus
 Anibal Drelichman, MD, MPH, FACP
Ph: 313-552-0620
  St. Joseph
 Lakeland Regional Cancer Care Center - St. Joseph
 Bilal Ansari, MD
Ph: 269-983-8260
  Traverse City
 Munson Medical Center
 Martin Bury
Ph: 231-935-6202
  Wyoming
 Metro Health Hospital
 Martin Bury
Ph: 616-252-7200
Minnesota
  Alexandria
 Donald Jurgens
Ph: 320-229-4907
  Bemidji
 MeritCare Bemidji
 Preston Steen, MD
Ph: 701-234-2397
  Burnsville
 Fairview Ridges Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Coon Rapids
 Mercy and Unity Cancer Center at Mercy Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Duluth
 CCOP - Duluth
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 Duluth Clinic Cancer Center - Duluth
 Clinical Trials Office - Duluth Clinic Cancer Center - Duluth
Ph: 218-786-3308
 Miller - Dwan Medical Center
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
  Edina
 Fairview Southdale Hospital
 Clinical Trials Office - Fairview Southdale Hospital
Ph: 612-625-3650
  Fergus Falls
 Donald Jurgens
Ph: 320-229-4907
  Fridley
 Mercy and Unity Cancer Center at Unity Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Mankato
 Immanuel St. Joseph's
 Glenn Harman, MD
Ph: 815-777-1536
  Maplewood
 Minnesota Oncology Hematology, PA - Maplewood
 Patrick Flynn, MD
Ph: 612-863-8585
  Minneapolis
 Veterans Affairs Medical Center - Minneapolis
 Clinical Trials Office - Veterans Affairs Medical Center - Minneapolis
Ph: 612-467-2800
 Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
 Clinical Trials Office - Virginia Piper Cancer Institute
Ph: 612-863-5654
  Robbinsdale
 Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
 Clinical Trials Office - Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
Ph: 763-520-1893
  Rochester
 Mayo Clinic Cancer Center
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Saint Cloud
 CentraCare Clinic - River Campus
 Donald Jurgens
Ph: 320-229-4907
 Coborn Cancer Center
 Donald Jurgens
Ph: 320-229-4907
  Saint Louis Park
 CCOP - Metro-Minnesota
 Patrick Flynn, MD
Ph: 612-863-8585
 Park Nicollet Cancer Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Saint Paul
 United Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Shakopee
 St. Francis Cancer Center at St. Francis Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Waconia
 Ridgeview Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Willmar
 Willmar Cancer Center at Rice Memorial Hospital
 Joseph Ryan, MD
Ph: 320-231-6359
  Woodbury
 Minnesota Oncology Hematology, PA - Woodbury
 Patrick Flynn, MD
Ph: 612-863-8585
Mississippi
  Hattiesburg
 Hattiesburg Clinic, PA at Forrest General
 Jyotsna Fuloria
Ph: 601-288-8282
 Hematology & Oncology Clinic
 Jyotsna Fuloria
Ph: 601-268-5150
  Jackson
 University of Mississippi Cancer Clinic
 Robert Hamilton
Ph: 601-984-5590
  Pascagoula
 Regional Cancer Center at Singing River Hospital
 James Clarkson, MD
Ph: 228-374-6296
Missouri
  Cape Girardeau
 Saint Francis Medical Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Chesterfield
 Saint Luke's Hospital
 Donald Busiek, MD
Ph: 314-205-6737
  Columbia
 Ellis Fischel Cancer Center at University of Missouri - Columbia
 Clinical Trial Office - Ellis Fischel Cancer Center
Ph: 573-882-7440
  Joplin
 Freeman Cancer Institute at Freeman Health System
 Anisa Hassan
Ph: 417-347-3066
  Saint Louis
 Arch Medical Services, Incorporated at Center for Cancer Care and Research
 Alan Lyss, MD
Ph: 314-996-5514
 CCOP - St. Louis-Cape Girardeau
 Bethany Sleckman, MD
Ph: 314-251-7057
 David C. Pratt Cancer Center at St. John's Mercy
 Clinical Trials Office - David C. Pratt Cancer Center at St. John's Mercy
Ph: 314-251-6770
 Midwest Hematology Oncology Group, Incorporated
 Bethany Sleckman, MD
Ph: 314-251-7057
 Missouri Baptist Cancer Center
 Alan Lyss, MD
Ph: 314-996-5514
 Saint Louis University Cancer Center
 Clinical Trials Office - Saint Louis University Cancer Center
Ph: 314-977-4440
 Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
 Joel Picus, MD
Ph: 314-362-5737
 St. Anthony's Cancer Center
 R. William Morris, MD
Ph: 314-849-6066
  Springfield
 CCOP - Cancer Research for the Ozarks
 Robert Carolla
Ph: 417-269-4520
 St. John's Regional Health Center
 Robert Carolla
Ph: 417-820-2000
Montana
  Billings
 Billings Clinic - Downtown
 Clinical Trials Office - Billings Clinic - Downtown
Ph: 800-996-2663
 Email: research@billingsclinic.org
 CCOP - Montana Cancer Consortium
 Benjamin Marchello, MD
Ph: 406-238-6290
 Hematology-Oncology Centers of the Northern Rockies - Billings
 Benjamin Marchello, MD
Ph: 406-238-6290
 Northern Rockies Radiation Oncology Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 St. Vincent Healthcare Cancer Care Services
 Benjamin Marchello, MD
Ph: 406-238-6290
  Bozeman
 Bozeman Deaconess Cancer Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Butte
 St. James Healthcare Cancer Care
 Benjamin Marchello, MD
Ph: 406-238-6290
  Great Falls
 Benjamin Marchello, MD
Ph: 406-238-6290
 Big Sky Oncology
 Clinical Trail Office - Big Sky Oncology
Ph: 406-731-8217
 Great Falls Clinic - Main Facility
 Benjamin Marchello, MD
Ph: 406-238-6290
 Sletten Cancer Institute at Benefis Healthcare
 Grant Harrer, MD, FACP, CCTI
Ph: 406-731-8100
  Havre
 Northern Montana Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Helena
 St. Peter's Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Kalispell
 Glacier Oncology, PLLC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Medical Oncology at KRMC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Regional Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Missoula
 Community Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 Guardian Oncology and Center for Wellness
 Benjamin Marchello, MD
Ph: 406-238-6290
 Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
 Clinical Trials Office - Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
Ph: 406-329-7029
 Montana Cancer Specialists at Montana Cancer Center
 Clinical Trials Office - Montana Cancer Specialists at Montana Cancer Center
Ph: 406-238-6962
Nebraska
  Grand Island
 Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center
 Jean Grem, MD
Ph: 402-559-6210
  Kearney
 Good Samaritan Cancer Center at Good Samaritan Hospital
 Clinical Trials Office - Good Samaritan Cancer Center at Good Samaritan Hospital
Ph: 308-865-7963
  Lincoln
 Cancer Resource Center - Lincoln
 Alan Berg, MD
Ph: 402-420-7000
  Omaha
 Alegant Health Cancer Center at Bergan Mercy Medical Center
 Clinical Trials Office - Alegant Health Cancer Center at Bergen Mercy Medical Center
Ph: 402-398-6060
 CCOP - Missouri Valley Cancer Consortium
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Creighton University Medical Center
 Clinical Trials Office - Creighton University Medical Center
Ph: 402-280-4100
 Immanuel Medical Center
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Methodist Estabrook Cancer Center
 Robert Langdon, MD
Ph: 402-399-8762
 UNMC Eppley Cancer Center at the University of Nebraska Medical Center
 Clinical Trials Office - UNMC Eppley Cancer Center at the University of Nebraska Medical Center
Ph: 800-999-5465
Nevada
  Carson City
 Carson Tahoe Cancer Center at Carson Tahoe Regional Medical Center
 John Kelly
Ph: 775-445-7508
877-284-2627
  Las Vegas
 CCOP - Nevada Cancer Research Foundation
 John Ellerton, MD, CM
Ph: 702-384-0013
 Nevada Cancer Institute
 Clinical Trials Office - Nevada Cancer Institute
Ph: 702-822-5136
 University Medical Center of Southern Nevada
 John Ellerton, MD, CM
Ph: 702-384-0013
  Reno
 Renown Institute for Cancer at Renown Regional Medical Center
 Vodur Reddy
Ph: 775-982-5050
866-559-0558
New Hampshire
  Concord
 New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
 Charles Catcher, MD
Ph: 603-224-2556
  Hooksett
 New Hampshire Oncology - Hematology, PA - Hooksett
 Charles Catcher, MD
Ph: 603-224-2556
  Laconia
 Lakes Region General Hospital
 Charles Catcher, MD
Ph: 603-224-2556
  Manchester
 Elliot Regional Cancer Center at Elliot Hospital
 Douglas Weckstein, MD
Ph: 603-622-6484
New Jersey
  East Orange
 Veterans Affairs Medical Center - East Orange
 Basil Kasimis, MD, DSc
Ph: 973-395-7809
  Flemington
 Hunterdon Regional Cancer Center at Hunterdon Medical Center
 Kenneth Blankstein, MD
Ph: 908-788-6100
  Freehold
 CentraState Medical Center
 Jeffrey Silberberg, MD
Ph: 732-431-8400
  Livingston
 St. Barnabas Medical Center Cancer Center
 Clinical Trials Office - St. Barnabas Medical Center Cancer Center
Ph: 973-322-2470
  Morristown
 Carol G. Simon Cancer Center at Morristown Memorial Hospital
 Steven Papish, MD
Ph: 973-538-5210
  New Brunswick
 Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
 Clinical Trials Office - Cancer Institute of New Jersey
Ph: 732-235-8675
  Ridgewood
 Valley Hospital - Ridgewood
 Allen Chinitz, MD
Ph: 201-634-5600
  Somerville
 Somerset Medical Center
 Clinical Trials Office - Somerset Medical Center
Ph: 908-685-2481
  Sparta
 Frederick R. and Betty M. Smith Cancer Treatment Center
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Summit
 Overlook Hospital
 Steven Papish, MD
Ph: 973-538-5210
  Vineland
 Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare
 Clinical Trials Office - Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare
Ph: 856-641-7933
  Voorhees
 Cancer Institute of New Jersey at Cooper - Voorhees
 Clinical Trials Office - Cancer Institute of New Jersey at Cooper University Hospital - Voorhees
Ph: 856-325-6757
New York
  Bronx
 Our Lady of Mercy Medical Center Comprehensive Cancer Center
 Janice Dutcher
Ph: 718-304-7200
  Buffalo
 Roswell Park Cancer Institute
 Clinical Trials Office - Roswell Park Cancer Institute
Ph: 877-275-7724
  New York
 Beth Israel Medical Center - Petrie Division
 Clinical Trials Office - Beth Israel Medical Center - Petrie Division
Ph: 212-844-6286
 New York Weill Cornell Cancer Center at Cornell University
 Clinical Trials Office - New York Weill Cornell Cancer Center at Cornell University
Ph: 212-746-1848
 NYU Cancer Institute at New York University Medical Center
 Howard Hochster, MD
Ph: 212-731-5100
 St. Luke's - Roosevelt Hospital Center - St.Luke's Division
 Peter Kozuch, MD
Ph: 212-523-6769
  Nyack
 Union State Bank Cancer Center at Nyack Hospital
 Clinical Trials Office - Union State Cancer Center at Nyack Hospital
Ph: 845-348-8507
  Rochester
 James P. Wilmot Cancer Center at University of Rochester Medical Center
 Richard Fisher, MD
Ph: 585-275-0842
 Lipson Cancer and Blood Center at Rochester General Hospital
 Peter Bushunow, MD
Ph: 585-922-4020
  Staten Island
 Nalitt Cancer Institute at Staten Island University Hospital
 Qun Dai
Ph: 718-226-6400
  Syracuse
 SUNY Upstate Medical University Hospital
 Clinical Trials Office - SUNY Upstate Medical University Hospital
Ph: 315-464-5476
  Utica
 Faxton Regional Cancer Center
 Contact Person
Ph: 315-624-5390
North Carolina
  Asheboro
 Randolph Hospital
 Clinical Trails Office - Randolph Hospital
Ph: 336-832-0821
  Asheville
 Mission Hospitals - Memorial Campus
 Clinical Trials Office - Mission Hospitals - Memorial Campus
Ph: 828-213-4150
  Burlington
 Alamance Cancer Center at Alamance Regional Medical Center
 Janak Choksi, MD
Ph: 336-538-7737
  Chapel Hill
 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
 Clinical Trials Office - Lineberger Comprehensive Cancer Center
Ph: 877-668-0683; 919-966-4432
  Charlotte
 Blumenthal Cancer Center at Carolinas Medical Center
 Clinical Trials Office - Blumenthal Cancer Center at Carolinas Medical Center
Ph: 704-355-2884
 Presbyterian Cancer Center at Presbyterian Hospital
 Clinical Trials Office - Presbyterian Cancer Center at Presbyterian Hospital
Ph: 704-384-5369
  Concord
 Batte Cancer Center at Northeast Medical Center
 James Wall, MD
Ph: 704-783-1370
  Durham
 Duke Comprehensive Cancer Center
 Clinical Trials Office - Duke Comprehensive Cancer Center
Ph: 888-275-3853
  Goldsboro
 Southeastern Medical Oncology Center - Goldsboro
 James Atkins, MD
Ph: 919-580-0000
 Wayne Memorial Hospital, Incorporated
 James Atkins, MD
Ph: 919-580-0000
  Greensboro
 Moses Cone Regional Cancer Center at Wesley Long Community Hospital
 Clinical Trials Office - Moses Cone Regional Cancer Center at Wesley Long Community Hospital
Ph: 336-621-8374
  Greenville
 Leo W. Jenkins Cancer Center at ECU Medical School
 Clinical Trials Office - Leo W. Jenkins Cancer Center at ECU Medical School
Ph: 252-744-2391
  Henderson
 Maria Parham Medical Center
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Kinston
 Kinston Medical Specialists
 Peter Watson, MD
Ph: 252-559-2200ext.201
  Lumberton
 Southeastern Regional Medical Center
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Oxford
 Granville Medical Center
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Raleigh
 Duke Health Raleigh Hospital
 Jeffrey Crawford, MD
Ph: 919-681-9509
 Rex Cancer Center at Rex Hospital
 Clinical Trials Office - Rex Cancer Center
Ph: 919-784-7209
  Reidsville
 Annie Penn Cancer Center
 Clinical Trials Office - Annie Penn Cancer Center
Ph: 336-621-8374
  Roxboro
 Person Memorial Hospital
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Rutherfordton
 Rutherford Hospital
 James Bearden, MD
Ph: 864-560-6812
North Dakota
  Bismarck
 Medcenter One Hospital Cancer Care Center
 Edward Wos, DO
Ph: 701-323-5741
  Fargo
 CCOP - MeritCare Hospital
 Preston Steen, MD
Ph: 701-234-2397
 Dakota Cancer Institute at Dakota Clinic - South University
 Mahendra Gupta
Ph: 701-364-8910
800-437-4054
 MeritCare Broadway
 Preston Steen, MD
Ph: 701-234-2397
Ohio
  Akron
 McDowell Cancer Center at Akron General Medical Center
 Esther Rehmus, MD
Ph: 330-344-6505
 Summa Center for Cancer Care at Akron City Hospital
 Clinical Trials Office - Akron City Hospital
Ph: 330-375-6101
  Bellefontaine
 Mary Rutan Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Bowling Green
 Wood County Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Canton
 Aultman Cancer Center at Aultman Hospital
 Clinical Trials Office - Aultman Cancer Center at Aultman Hospital
Ph: 330-363-6891
  Chillicothe
 Adena Regional Medical Center
 Clinical Trials Office - Adena Regional Medical Center
Ph: 877-779-7585
  Cleveland
 Case Comprehensive Cancer Center
 Clinical Trials Office - Case Comprehensive Cancer Center
Ph: 800-641-2422
 MetroHealth Cancer Care Center at MetroHealth Medical Center
 Bruce Averbook, MD, FACS
Ph: 216-778-4795
  Clyde
 North Coast Cancer Care - Clyde
 Paul Schaefer, MD
Ph: 419-479-5605
  Columbus
 CCOP - Columbus
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Doctors Hospital at Ohio Health
 Clinical Trials Office - Doctors Hospital at Ohio Health
Ph: 614-566-3275
 Grant Medical Center Cancer Care
 Clinical Trials Office - Grant Medical Center Cancer Care
Ph: 614-566-4475
 Mount Carmel Health - West Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Riverside Methodist Hospital Cancer Care
 Clinical Trials Office - Riverside Methodist Hospital Cancer Care
Ph: 614-566-4475
  Dayton
 CCOP - Dayton
 Howard Gross, MD
Ph: 937-832-1093
 David L. Rike Cancer Center at Miami Valley Hospital
 Clinical Trials Office - David L. Rike Cancer Center at Miami Valley Hospital
Ph: 937-208-2079
 Good Samaritan Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Grandview Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Samaritan North Cancer Care Center
 Howard Gross, MD
Ph: 937-832-1093
  Delaware
 Grady Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Elyria
 Hematology Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Findlay
 Blanchard Valley Medical Associates
 Howard Gross, MD
Ph: 937-832-1093
  Franklin
 Middletown Regional Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Greenville
 Wayne Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Kettering
 Charles F. Kettering Memorial Hospital
 Clinical Trials Office - Charles F. Kettering Memorial Hospital
Ph: 937-298-3399 ext. 57556
  Lancaster
 Fairfield Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Lima
 Lima Memorial Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Rita's Medical Center
 Clinical Trials Office - St. Rita's Medical Center
Ph: 419-226-9617
  Mansfield
 MedCentral - Mansfield Hospital
 Clinical Trials Office - MedCentral - Mansfield Hospital
Ph: 419-526-8938
  Marietta
 Strecker Cancer Center at Marietta Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Maumee
 Northwest Ohio Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Luke's Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
  Newark
 Licking Memorial Cancer Care Program at Licking Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Norwalk
 Fisher-Titus Medical Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Oregon
 St. Charles Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic - Oregon
 Paul Schaefer, MD
Ph: 419-479-5605
  Sandusky
 North Coast Cancer Care, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Springfield
 Community Hospital of Springfield and Clark County
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Mercy Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Sylvania
 Flower Hospital Cancer Center
 Clinical Trials Office - Flower Hospital Cancer Center
Ph: 419-824-1842
  Tiffin
 Mercy Hospital of Tiffin
 Paul Schaefer, MD
Ph: 419-479-5605
  Toledo
 CCOP - Toledo Community Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Medical University of Ohio Cancer Center
 Clinical Trials Office - Medical University of Ohio Cancer Center
Ph: 419-383-6583
 St. Anne Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Vincent Mercy Medical Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic, Incorporated - Main Clinic
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Hospital
 Clinical Trials Office - Toledo Hospital
Ph: 419-824-1842
  Troy
 UVMC Cancer Care Center at Upper Valley Medical Center
 Clinical Trials Office - UVMC Cancer Care Center at Upper Valley Medical Center
Ph: 937-440-4842
  Wauseon
 Fulton County Health Center
 Clinical Trials Office - Fulton County Health Center
Ph: 419-330-2708
  Westerville
 Mount Carmel St. Ann's Cancer Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Wilmington
 Clinton Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Xenia
 Ruth G. McMillan Cancer Center at Greene Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Zanesville
 Genesis - Good Samaritan Hospital
 Clinical Trials Office - Genesis - Good Samaritan Hospital
Ph: 740-454-5232
Oklahoma
  Lawton
 Cleo Craig Cancer Research Clinic
 Nadim Nimeh, MD
Ph: 580-536-2121ext.113
  Oklahoma City
 Cancer Care Associates - Mercy Campus
 Howard Ozer, MD, PhD
Ph: 405-271-4022
 Integris Oncology Services
 Karl Boatman, MD
Ph: 405-949-3870
 Oklahoma University Cancer Institute
 Howard Ozer, MD, PhD
Ph: 405-271-4022
Oregon
  Bend
 St. Charles Medical Center - Bend
 William Martin
Ph: 503-382-4321
  Coos Bay
 Bay Area Hospital
 Bret Cook, MD
Ph: 541-267-5151
  Milwaukie
 Providence Milwaukie Hospital
 Keith Lanier, MD
Ph: 503-299-6500
  Portland
 Adventist Medical Center
 Keith Lanier, MD
Ph: 503-299-6500
 CCOP - Columbia River Oncology Program
 Keith Lanier, MD
Ph: 503-299-6500
 Providence Cancer Center at Providence Portland Medical Center
 Clinical Trials Office - Providence Cancer Center at Providence Portland Medical Center
Ph: 503-215-6412
 Providence St. Vincent Medical Center
 Clinical Trials Office - Providence St. Vincent Medical Center
Ph: 503-215-6412
  Salem
 Salem Hospital Regional Cancer Care Services
 Clinical Trials Office - Salem Hospital Regional Cancer Care Services
Ph: 503-561-2618
Pennsylvania
  Allentown
 Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
 Eliot Friedman, MD
Ph: 610-402-0512
  Bethlehem
 St. Luke's Cancer Network at St. Luke's Hospital
 Sanjiv Agarwala, MD
Ph: 610-954-2145
  Bryn Mawr
 Bryn Mawr Hospital
 Clinical Trials Office - Bryn Mawr Hospital
Ph: 610-645-2680
  Doylestown
 Doylestown Hospital Cancer Center
 Mitchell Alden, DO
Ph: 215-345-8444
  East Stroudsburg
 Dale and Frances Hughes Cancer Center at Pocono Medical Center
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Ephrata
 Ephrata Cancer Center at Ephrata Community Hospital
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Harrisburg
 PinnacleHealth Regional Cancer Center at Polyclinic Hospital
 Oncology Clinical Trial Coordinator
Ph: 717-782-4750
  Hershey
 Penn State Cancer Institute at Milton S. Hershey Medical Center
 Clinical Trials Office - Penn State Cancer Institute at Milton S. Hershey Medical Center
Ph: 717-531-3779
 Email: CTO@hmc.psu.edu
  Langhorne
 St. Mary Regional Cancer Center
 Clinical Trials Office - St. Mary Regional Cancer Center
Ph: 215-710-4585
  Lewistown
 Lewistown Hospital
 Yixing Jiang
Ph: 717-242-7143
  Media
 Riddle Memorial Hospital Cancer Center
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
  Paoli
 Cancer Center of Paoli Memorial Hospital
 Clinical Trials Office - Cancer Center of Paoli Memorial Hospital
Ph: 610-648-1637
  Philadelphia
 Abramson Cancer Center of the University of Pennsylvania
 Clinical Trials Office - Abramson Cancer Center of the University of Pennsylvania
Ph: 800-474-9892
 Fox Chase Cancer Center - Philadelphia
 Clinical Trials Office - Fox Chase Cancer Center - Philadelphia
Ph: 215-728-4790
 Joan Karnell Cancer Center at Pennsylvania Hospital
 Bernard Mason, MD
Ph: 215-829-6088
 Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
 Clinical Trials Office - Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
Ph: 215-955-6084
  Pittsburgh
 Allegheny Cancer Center at Allegheny General Hospital
 James Celebrezze, Jr.
Ph: 412-359-3336
866-680-0004
 UPMC Cancer Centers
 Clinical Trials Office - UPMC Cancer Centers
Ph: 412-647-8073
  Pottstown
 Pottstown Memorial Regional Cancer Center
 Wei Song, MD, PhD
Ph: 610-327-7555
  Reading
 McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center
 Clinical Trials Office - McGlinn Family Regional Cancer Center
Ph: 610-988-9323
  Sayre
 Guthrie Cancer Center at Guthrie Clinic Sayre
 Clinical Trials Office - Guthrie Cancer Center at Guthrie Clinic Sayre
Ph: 800-836-0388
  Scranton
 Hematology and Oncology Associates of Northeastern Pennsylvania
 Edith Mitchell, MD, FACP
Ph: 215-955-8874
 Martin Hyzinski, MD
Ph: 570-558-3020
 Mercy Hospital Cancer Center - Scranton
 Martin Hyzinski, MD
Ph: 570-558-3020
  Sellersville
 Grand View Hospital
 Anthony Magdalinski, III
Ph: 215-453-4000
  State College
 Mount Nittany Medical Center
 Yixing Jiang
Ph: 814-231-7000
  West Grove
 Jennersville Regional Hospital
 Clinical Trials Office - Jennersville Regional Hospital
Ph: 610-869-1396
  Wynnewood
 CCOP - Main Line Health
 Paul Gilman, MD
Ph: 610-645-2000
 Lankenau Cancer Center at Lankenau Hospital
 Paul Gilman, MD
Ph: 610-645-2000
  York
 York Cancer Center at Apple Hill Medical Center
 Amir Tabatabai, MD
Ph: 717-741-9229
Rhode Island
  Cranston
 Hematology and Oncology Associates of Rhode Island
 Adam Olszewski
Ph: 401-943-4660
  Warwick
 Kent County Memorial Hospital
 Clinical Trials Office - Kent County Memorial Hospital
Ph: 401-737-7010 ext. 1864
South Carolina
  Anderson
 AnMed Cancer Center
 Clinical Trials Office - AnMed Cancer Center
Ph: 864-512-1000
  Beaufort
 Keyserling Cancer Center at Beaufort Memorial Hospital
 Majd Chahin
Ph: 877-532-6472
888-522-5585
  Georgetown
 Georgetown Memorial Hospital
 Darren Mullins
Ph: 843-527-7000
  Greenville
 CCOP - Greenville
 Jeffrey Giguere, MD, FACP
Ph: 864-987-7000
  Spartanburg
 CCOP - Upstate Carolina
 Clinical Trials Office - CCOP - Upstate Carolina
Ph: 800-486-5941
 Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
 Clinical Trials Office - Gibbs Regional Cancer Center
Ph: 800-486-5941
South Dakota
  Sioux Falls
 Avera Cancer Institute
 Loren Tschetter, MD
Ph: 605-328-8000
Tennessee
  Kingsport
 Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center
 Clinical Trials Office - Christine LaGuardia Phillips Cancer Center
Ph: 423-224-5593
  Knoxville
 Thompson Cancer Survival Center
 Clinical Trials Office - Thompson Cancer Survival Center
Ph: 865-541-1812
 U.T. Medical Center Cancer Institute
 Clinical Trials Office - U.T. Medical Center Cancer Institute
Ph: 865-544-9773
Texas
  Amarillo
 Harrington Cancer Center
 Clinical Trials Officec - Harrington Cancer Center
Ph: 806-359-4673
 Email: ryokubaitis@harringtoncc.org
  Austin
 Southwest Regional Cancer Center - Central
 Clinical Trials Office - Southwest Regional Cancer Center - Central
Ph: 512-421-4163
 Texas Oncology, PA - Austin North
 Beth Hellerstedt
Ph: 512-873-8900
 Texas Oncology, PA - Austin Northwest
 Beth Hellerstedt
Ph: 512-349-0081
 Texas Oncology, PA at South Austin Cancer Center
 Beth Hellerstedt
Ph: 512-447-2202
 Texas Oncology, PA at Texas Oncology Cancer Center - Central
 Beth Hellerstedt
Ph: 512-302-1771
  Cedar Park
 Texas Oncology, PA - Cedar Park
 Beth Hellerstedt
Ph: 512-260-6050
  Dallas
 Parkland Memorial Hospital
 James Knox Willson, Jr.
Ph: 214-590-5582
 Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
 Clinical Trials Office - Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
Ph: 866-460-4673; 214-648-7097
 UT Southwestern University Hospital - Zale Lipshy
 James Knox Willson, Jr.
Ph: 214-590-3000
  Houston
 Baylor University Medical Center - Houston
 Martha Mims
Ph: 713-798-8070
 Ben Taub General Hospital
 Martha Mims
Ph: 713-873-2000
 Methodist Hospital
 Martha Mims
Ph: 713-441-1010
 St. Luke's Texas Cancer Institute at St. Luke's Episcopal Hospital
 Martha Mims
Ph: 832-355-3490
 Veterans Affairs Medical Center - Houston
 Martha Mims
Ph: 713-794-7111
800-553-2278
  Round Rock
 Texas Oncology, PA - Seton Williamson
 Beth Hellerstedt
Ph: 512-687-2300
 Texas Oncology, PA at Texas Cancer Center Round Rock
 Beth Hellerstedt
Ph: 512-341-8724
  San Marcos
 Texas Oncology, PA - San Marcos
 Beth Hellerstedt
Ph: 512-396-5199
888-340-9753
  Temple
 CCOP - Scott and White Hospital
 Lucas Wong, MD
Ph: 254-724-1053
Utah
  American Fork
 American Fork Hospital
 R. Jeffrey Lee, MD