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Cost of Clinical Trials
    Reviewed: 01/08/2010
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Clinical Trials
This fact sheet covers types of clinical trials, who sponsors them, how they are conducted, how participants are protected, and who pays for the patient care costs associated with a clinical trial. Includes some questions to ask a health care provider before entering a clinical trial.

Search for Clinical Trials
NCI's PDQ® Cancer Clinical Trials Registry.
A number of studies have found that patient care costs for clinical trials are not appreciably higher than costs for patients not enrolled in trials. These findings discredit claims made by some insurance companies that paying for clinical trials will send their expenses skyward.
NCI Materials
States That Require Health Plans to Cover Patient Care Costs in Clinical Trials
A searchable list and map of U.S. states that require health plans to pay for the patient care costs associated with clinical trials. Key provisions are summarized.

Clinical Trials and Insurance Coverage
Information about insurance coverage of the patient care costs associated with clinical trials.

Cost of Treating Cancer Patients in Clinical Trials Just Slightly Higher
The most comprehensive study yet on the issue confirms that there are only slightly higher patient-care costs associated with treating patients in cancer clinical trials compared to treating similar patients outside of trials, according to the June 11, 2003, issue of the Journal of the American Medical Association.

Clinical Trials Appear Not to Drive Up Cost of Cancer Treatment
Some health insurers, concerned that participation in a clinical trial drives up the cost of cancer care, decline coverage to patients enrolled in cancer trials. However, the results of an April 2001 study by Thomas N. Chirikos, Ph.D. and others at the H. Lee Moffitt Cancer Center in Tampa, Florida, offer no basis for such a policy.

The Cost of Cancer Care in Clinical Trials
NCI has supported a number of studies that investigate the cost of patient care for patients enrolled in NCI-sponsored clinical trials compared to care received for comparable patients in standard community care. These data are essential to inform ongoing policy debates about the financial coverage by public and private health insurance plans of care received in cancer clinical trials.

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