Featured Clinical Trials Supported by the National Cancer Institute
Today, thousands of cancer clinical trials are under way in the United States. Clinical trials answer vital research questions that lead to better screening, prevention, diagnosis, and treatment options for all cancers. This section highlights NCI-supported cancer trials featured in the NCI Cancer Bulletin and demonstrates the breadth of clinical cancer research supported by NCI.
To find other cancer trials open to enrollment:
- Call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237) for information about trials all across the country. The call is toll-free and completely confidential.
- Use the clinical trials search form to look online for trials listed on NCI's Cancer.gov Web site. The form has a Help link for tips about searching for clinical trials.
- For information about cancer trials taking place on the National Institutes of Health campus in Bethesda, Maryland, call NCI’s Clinical Trials Referral Office at 1-888-NCI-1937 (1-888-624-1937). The call is toll-free and completely confidential.
Dietary Intervention for Patients Receiving Chemoradiotherapy for Lung Cancer
(Posted: 11/13/2012) - In this phase I clinical trial, patients with advanced non-small cell lung cancer who are about to undergo chemoradiation therapy will consume a very low-carbohydrate ketogenic diet for the duration of their treatment.
Comparing Relaxation Programs for Breast Cancer Patients Receiving Radiotherapy
(Posted: 10/16/2012) - In this study, women with breast cancer who have had surgery and are scheduled to undergo radiation therapy will be randomly assigned to one of two different stretching and relaxation programs or to a control group that will receive usual care.
Comparing Radiation Therapy Regimens for Early-Stage Breast Cancer
(Posted: 10/02/2012) - In this phase III clinical trial, women with early-stage breast cancer will be randomly assigned to undergo a standard 5-week course of whole-breast irradiation (WBI) followed by a sequential boost course or 3 weeks of hypofractionated WBI with a concurrent boost.
Treating KSHV-Associated Multicentric Castleman Disease
(Posted: 09/18/2012) - In this pilot study, patients with KSHV-associated multicentric Castleman disease will receive intravenous tocilizumab every other week for up to 12 weeks. Patients who do not benefit from tocilizumab therapy alone may go on to receive high-dose AZT and valganciclovir in addition to tocilizumab.
Targeting Invasive Glioma Cells
(Posted: 09/04/2012) - In this trial, patients with glioblastoma that has not responded to standard postoperative therapy or that has progressed will be treated with varying amounts of a Trk inhibitor called AZD7451 to determine the maximum tolerated dose and the side effects of this drug.
(Posted: 11/13/2012) - In this phase I clinical trial, patients with advanced non-small cell lung cancer who are about to undergo chemoradiation therapy will consume a very low-carbohydrate ketogenic diet for the duration of their treatment.
Comparing Relaxation Programs for Breast Cancer Patients Receiving Radiotherapy
(Posted: 10/16/2012) - In this study, women with breast cancer who have had surgery and are scheduled to undergo radiation therapy will be randomly assigned to one of two different stretching and relaxation programs or to a control group that will receive usual care.
Comparing Radiation Therapy Regimens for Early-Stage Breast Cancer
(Posted: 10/02/2012) - In this phase III clinical trial, women with early-stage breast cancer will be randomly assigned to undergo a standard 5-week course of whole-breast irradiation (WBI) followed by a sequential boost course or 3 weeks of hypofractionated WBI with a concurrent boost.
Treating KSHV-Associated Multicentric Castleman Disease
(Posted: 09/18/2012) - In this pilot study, patients with KSHV-associated multicentric Castleman disease will receive intravenous tocilizumab every other week for up to 12 weeks. Patients who do not benefit from tocilizumab therapy alone may go on to receive high-dose AZT and valganciclovir in addition to tocilizumab.
Targeting Invasive Glioma Cells
(Posted: 09/04/2012) - In this trial, patients with glioblastoma that has not responded to standard postoperative therapy or that has progressed will be treated with varying amounts of a Trk inhibitor called AZD7451 to determine the maximum tolerated dose and the side effects of this drug.
