Multiple Cancer Types - Featured Clinical Trials
First-in-Humans Study of New Immunotherapy Agent
(Posted: 01/24/2012) - In this first-in-humans clinical trial of interleukin-15 (IL-15), patients with metastatic melanoma or metastatic renal cell cancer who have not benefited from other therapies will be given IL-15 by intravenous injection once a day for 12 days.
Comparing Postoperative Radiation Therapies for Brain Metastases
(Posted: 12/13/2011) - In this clinical trial, patients with one to four brain metastases who have had at least one of the metastatic tumors removed surgically will be randomly assigned to undergo whole-brain radiation therapy or stereotactic radiosurgery.
Vaccine Therapy for Patients with Recurrent Blood Cancers
(Posted: 05/04/2010) - In this phase I/II trial, patients with blood cancer that has recurred after allogeneic stem cell transplantation will be treated with donor T-lymphocyte infusions and a dendritic cell vaccine that is designed to trigger an immune response against cells producing a protein called Wilms tumor 1 (WT1).
Extending Targeted Immune Depletion to Unrelated Cord Blood Transplantation
(Posted: 03/09/2010) - In this pilot study, patients with leukemia, lymphoma, multiple myeloma, or certain premalignant blood disorders (such as myelodysplastic syndromes) will undergo targeted immune-depleting chemotherapy followed by unrelated double cord blood transplant.
PARP Inhibitor and Metronomic Chemotherapy for Refractory Cancer
(Posted: 01/12/2010) - In this clinical trial, patients with solid tumors or lymphomas that have not responded to previous treatment (refractory cancer), or for which no effective treatment exists, will receive the PARP inhibitor ABT-888 and metronomic cyclophosphamide.
(Posted: 01/24/2012) - In this first-in-humans clinical trial of interleukin-15 (IL-15), patients with metastatic melanoma or metastatic renal cell cancer who have not benefited from other therapies will be given IL-15 by intravenous injection once a day for 12 days.
Comparing Postoperative Radiation Therapies for Brain Metastases
(Posted: 12/13/2011) - In this clinical trial, patients with one to four brain metastases who have had at least one of the metastatic tumors removed surgically will be randomly assigned to undergo whole-brain radiation therapy or stereotactic radiosurgery.
Vaccine Therapy for Patients with Recurrent Blood Cancers
(Posted: 05/04/2010) - In this phase I/II trial, patients with blood cancer that has recurred after allogeneic stem cell transplantation will be treated with donor T-lymphocyte infusions and a dendritic cell vaccine that is designed to trigger an immune response against cells producing a protein called Wilms tumor 1 (WT1).
Extending Targeted Immune Depletion to Unrelated Cord Blood Transplantation
(Posted: 03/09/2010) - In this pilot study, patients with leukemia, lymphoma, multiple myeloma, or certain premalignant blood disorders (such as myelodysplastic syndromes) will undergo targeted immune-depleting chemotherapy followed by unrelated double cord blood transplant.
PARP Inhibitor and Metronomic Chemotherapy for Refractory Cancer
(Posted: 01/12/2010) - In this clinical trial, patients with solid tumors or lymphomas that have not responded to previous treatment (refractory cancer), or for which no effective treatment exists, will receive the PARP inhibitor ABT-888 and metronomic cyclophosphamide.
