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Featured Clinical Trials

Highlighted NCI-Supported Cancer Studies

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Featured Clinical Trials Supported by the National Cancer Institute

Today, thousands of cancer clinical trials are under way in the United States. Clinical trials answer vital research questions that lead to better screening, prevention, diagnosis, and treatment options for all cancers. This section highlights NCI-supported cancer trials and demonstrates the breadth of clinical cancer research supported by the Institute.

To find other cancer trials open to enrollment:

  • Call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237) for information about trials all across the country. The call is toll-free and completely confidential.
  • Use the clinical trials search form to look online for trials listed on NCI's website. The form has a Help link for tips about searching for clinical trials.
  • For information about cancer trials taking place on the National Institutes of Health campus in Bethesda, Maryland, call NCI’s Clinical Trials Referral Office at 1-888-NCI-1937 (1-888-624-1937). The call is toll-free and completely confidential.
Cetuximab and Chemoradiotherapy for Locally Advanced Esophageal Cancer
(Posted: 05/19/2009) - In this trial, patients with locally advanced esophageal cancer will undergo chemoradiotherapy using the drugs cisplatin and paclitaxel, and half of them will be randomly assigned to also receive the biologic agent cetuximab.

Tomotherapy for Patients with Limited Metastatic Cancer
(Posted: 04/21/2009) - In this trial, patients with limited metastatic tumors outside the brain will be treated with a type of radiation therapy called helical tomotherapy.

Targeting Resistance to Endocrine Therapy in Advanced Breast Cancer
(Posted: 04/07/2009) - In this phase III clinical trial, women with advanced, hormone receptor-positive breast cancer will be randomly assigned to receive hormonal therapy (with letrozole or tamoxifen) and either bevacizumab or a placebo.

Helping Survivors of Childhood Cancer Quit Smoking
(Posted: 03/24/2009) - In this study, adult survivors of childhood cancer who smoke and want to quit will be randomly assigned to one of two quitline-based strategies: counselor-initiated quitline consultations or self-paced quitline consultations.

Lenalidomide Maintenance Therapy for Multiple Myeloma
(Posted: 02/24/2009) - In this trial, researchers are exploring whether maintenance therapy with lenalidomide after single autologous stem cell transplantation can slow or prevent the return of multiple myeloma in patients who have undergone induction therapy.

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