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Featured Clinical Trials

Highlighted NCI-Supported Cancer Studies

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Featured Clinical Trials Supported by the National Cancer Institute


Today, thousands of cancer clinical trials are under way in the United States. Clinical trials answer vital research questions that lead to better screening, prevention, diagnosis, and treatment options for all cancers. This section highlights NCI-supported cancer trials and demonstrates the breadth of clinical cancer research supported by the Institute.

To find other cancer trials open to enrollment:

  • Call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237) for information about trials all across the country. The call is toll-free and completely confidential.
  • Use the clinical trials search form to look online for trials listed on NCI's Cancer.gov website. The form has a Help link for tips about searching for clinical trials.
  • For information about cancer trials taking place on the National Institutes of Health campus in Bethesda, Maryland, call NCI’s Clinical Trials Referral Office at 1-888-NCI-1937 (1-888-624-1937). The call is toll-free and completely confidential.
New Combination Therapy for Untreated Multiple Myeloma
(Posted: 02/26/2013) - In this phase II trial, people with newly diagnosed multiple myeloma will be treated with carfilzomib, lenalidomide, and dexamethasone for eight 28-day treatment cycles.

Refining Post-Surgical Therapy for Women with Lymph Node-Positive Breast Cancer
(Posted: 02/05/2013) - In this phase III trial, women with HER2-negative, HR-positive breast cancer and 1-3 positive lymph nodes with recurrence scores of 25 or lower will be randomly assigned either to undergo adjuvant chemotherapy before starting endocrine therapy or to begin endocrine therapy without chemotherapy.

Experimental Drug for Relapsed or Resistant Ovarian Cancer
(Posted: 01/08/2013) - In this trial, women with metastatic or unresectable epithelial ovarian, fallopian tube, or primary peritoneal cancer that has recurred after, or has not responded to, previous therapies will receive the experimental drug birinapant.

Treating Patients with High-Risk Smoldering Myeloma
(Posted: 12/11/2012) - In this phase III clinical trial, patients with smoldering myeloma classified as high risk for progression will be randomly assigned to undergo standard observation or six 4-week courses of treatment with the drug lenalidomide.

Dietary Intervention for Patients Receiving Chemoradiotherapy for Lung Cancer
(Posted: 11/13/2012) - In this phase I clinical trial, patients with advanced non-small cell lung cancer who are about to undergo chemoradiation therapy will consume a very low-carbohydrate ketogenic diet for the duration of their treatment.

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