Featured Clinical Trials Supported by the National Cancer Institute
Today, thousands of cancer clinical trials are under way in the United States. Clinical trials answer vital research questions that lead to better screening, prevention, diagnosis, and treatment options for all cancers. This section highlights NCI-supported cancer trials and demonstrates the breadth of clinical cancer research supported by the Institute.
To find other cancer trials open to enrollment:
- Call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237) for information about trials all across the country. The call is toll-free and completely confidential.
- Use the clinical trials search form to look online for trials listed on NCI's Cancer.gov website. The form has a Help link for tips about searching for clinical trials.
- For information about cancer trials taking place on the National Institutes of Health campus in Bethesda, Maryland, call NCI’s Clinical Trials Referral Office at 1-888-NCI-1937 (1-888-624-1937). The call is toll-free and completely confidential.
- Preventing Chemotherapy-Induced Neuropathy
(Posted: 04/03/2007, Updated: 02/19/2008) - In this trial, researchers are testing the ability of an antioxidant supplement called alpha-lipoic acid to prevent peripheral neuropathy caused by the platinum-containing drugs cisplatin and oxaliplatin.
- Combination Therapy for Invasive Bladder Cancer
(Posted: 02/05/2008) - In this clinical trial, patients with invasive bladder cancer who are not suitable for cystectomy will be treated with the drug paclitaxel and daily radiation therapy. Additionally, patients whose tumors test positive for a protein called HER2 will be treated with the monoclonal antibody trastuzumab (Herceptin).
- Inhibiting Tumor Angiogenesis in Children
(Posted: 01/22/2008) - In this trial, researchers are testing an angiogenesis inhibitor called cediranib in pediatric patients who have solid tumors (except brain tumors) or acute myeloid leukemia (AML), a type of blood cancer.
- Adjuvant Biological Therapy for Pancreatic Cancer
(Posted: 10/10/2006, Updated: 01/15/2008) - In this trial, patients with completely resected pancreatic cancer will receive adjuvant chemotherapy and radiation therapy plus additional treatment with either bevacizumab or cetuximab, monoclonal antibodies that target different proteins important for cancer growth and spread.
- Stress Management Therapy for Chemotherapy Patients
(Posted: 01/08/2008) - In this study, patients with newly diagnosed cancer and scheduled to undergo chemotherapy will be randomly assigned to one of two groups. One group will receive standard psychosocial care along with stress management training, while the other will receive standard psychosocial care alone.