Featured Clinical Trials Supported by the National Cancer Institute
Today, thousands of cancer clinical trials are under way in the United States. Clinical trials answer vital research questions that lead to better screening, prevention, diagnosis, and treatment options for all cancers. This section highlights NCI-supported cancer trials and demonstrates the breadth of clinical cancer research supported by the Institute.
To find other cancer trials open to enrollment:
- Call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237) for information about trials all across the country. The call is toll-free and completely confidential.
- Use the clinical trials search form to look online for trials listed on NCI's Cancer.gov website. The form has a Help link for tips about searching for clinical trials.
- For information about cancer trials taking place on the National Institutes of Health campus in Bethesda, Maryland, call NCI’s Clinical Trials Referral Office at 1-888-NCI-1937 (1-888-624-1937). The call is toll-free and completely confidential.
- Carnitine Supplementation for Cancer-Related Fatigue
(Posted: 01/03/2006, Updated: 11/07/2007) - In this trial, researchers will assess the prevalence of carnitine deficiencies in cancer patients and examine the effect of carnitine supplementation in patients experiencing moderate to severe fatigue.
- Chemotherapy for Recurrent Gliomas
(Posted: 02/14/2006, Updated: 11/07/2007) - In this clinical trial, researchers are testing a new drug called enzastaurin in patients whose glioma has recurred after previous radiotherapy and chemotherapy.
- Combination Chemotherapy for Liver Cancer
(Posted: 11/29/2005, Updated: 11/07/2007) - In this clinical trial, researchers are adding a new drug called bortezomib to chemotherapy with doxorubicin to see if it can cause liver tumors to shrink or stop growing better than doxorubicin alone.
- Targeted Combinations for Metastatic Kidney Cancer
(Posted: 11/06/2007) - In this trial, doctors are testing different combinations of the molecularly targeted agents bevacizumab, sorafenib, and temsirolimus in patients with metastatic kidney cancer.
- Treating Colorectal Cancer Liver Metastases
(Posted: 01/16/2007, Updated: 10/23/2007) - In this trial, colorectal cancer patients with six or fewer hepatic metastases will undergo primary surgery and/or ablation and then be treated with oxaliplatin and capecitabine. Half of the patients will receive additional chemotherapy consisting of floxuridine pumped directly into their livers through an arterial catheter and pump.