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How do I find out about NCI priorities for clinical questions in different diseases?

NCI's Cancer Therapy Evaluation Program (CTEP), Clinical Investigations Branch (CIB) organizes comprehensive programs of treatment clinical trials. Requests or questions regarding NCI priorities for clinical questions should be directed to the CIB investigator responsible for that disease area. A list of CTEP CIB staff and associated responsibilities can be found here.

How do I find out about current NCI-sponsored clinical trials?

You can search NCI's list of 8,000+ clinical trials now accepting participants.

What is the process for submitting a proposal for a phase III trial?

To submit a proposal for a phase III trial, the following steps are required:

Step 1.Use the NCI Concept Template (Microsoft Word Document) or an individual Cooperative Group template.
Step 2.Submit the concept to one or more of the NCI's cooperative groups. Each group reviews concepts internally, at the level of a disease committee, then again at a scientific prioritization committee.
Step 3.The Cooperative Group will send the concept to the relevant NCI disease-specific task force, which will provide feedback to the Group and the investigator.
Step 4.The Cooperative Group will consider the comments from the NCI disease-specific task force.
Step 5.If the Cooperative Group still wishes to proceed, they will propose the concept to the relevant NCI disease-specific steering committee. That steering committee must approve the concept for development.
Step 6.If the NCI disease-specific steering committee approves the concept, then the Cooperative Group develops a final protocol document, which must be reviewed for technical completeness by NCI.