National Cancer Institute National Cancer Institute
U.S. National Institutes of Health National Cancer Institute
NCI Home Cancer Topics Clinical Trials Cancer Statistics Research & Funding News About NCI
Which Study Results Are the Most Helpful in Making Cancer Care Decisions?
    Posted: 06/12/2003



Introduction






Clinical Trials Are Experimental & Prospective






What's a Phase III Clinical Trial?






Controlled Studies Allow Comparisons






Randomization: Chance, Not Choice






To Blind or Not to Blind






Study Size Matters






Example 1: A Cancer Treatment Trial






Example 2: A Cancer Prevention Trial







Summary: Questions to Ask About a Cancer Study



Page Options
Print This Page  Print This Page
Print This Document  Print This Document
View Entire Document  View Entire Document
E-Mail This Document  E-Mail This Document
Quick Links
Director's Corner

Dictionary of Cancer Terms

NCI Drug Dictionary

Funding Opportunities

NCI Publications

Advisory Boards and Groups

Science Serving People

Español
NCI Highlights
Colorectal Cancer Drugs Require Careful Patient Selection

Cetuximab for Advanced Lung Cancer

Past Highlights
BreastCancerTrials.org
Summary: Questions to Ask About a Cancer Study

In summary, the following questions may help as you look through various cancer studies, looking for the most medically definitive findings:

Question
Look For
  • Was the study a clinical trial? In other words, was the study experimental (there was an intervention that people were asked to take or do) and prospective (investigators followed study participants forward in time)?
A study that is both
experimental and prospective
  • What phase was the trial -- phase I, phase II or phase III?
A phase III study
  • Did the clinical trial have a control group? That is, did one group of participants receive the experimental intervention while another did not?
A controlled study
  • Were participants randomly assigned to either the investigational group or the control group?
A randomized study
  • How many participants were enrolled in the study?
A study that is large enough for the results to be statistically significant;
not due to chance

Back to TopBack to Top

< Previous Section


A Service of the National Cancer Institute
Department of Health and Human Services National Institutes of Health USA.gov