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Breast Cancer Trial Results
1. Trastuzumab Benefits Women with Locally Advanced or Inflammatory Breast Cancer (Posted: 03/15/2010) - Women treated with trastuzumab (Herceptin) and chemotherapy before surgery and trastuzumab again after surgery had a reduced risk of the disease recurring or progressing compared with women who received pre-surgical chemotherapy but no trastuzumab, according to a study published in the January 30, 2010, Lancet.

2. Shorter Course of Radiation Effective and Safe for Some Women with Early-stage Breast Cancer (Posted: 03/15/2010) - Giving radiation therapy in fewer but larger doses may be an alternative to standard radiation therapy for some women with early-stage breast cancer, according to a study published in the February 11, 2010, New England Journal of Medicine.

3. Acupuncture Reduces Joint Pain in Some Women with Breast Cancer (Posted: 02/03/2010) - In a small randomized clinical trial, breast cancer patients experiencing joint pain and stiffness from aromatase inhibitor (AI) treatment reported an improvement in pain from acupuncture.

4. Home Care Nursing Improves Cancer Symptom Management (Posted: 12/16/2009) - Home care nursing (HCN) improves the management of symptoms in breast and colorectal cancer patients who take the oral chemotherapy drug capecitabine, according to a study published online November 16, 2009, in the Journal of Clinical Oncology.

5. Letrozole More Effective Than Tamoxifen in Early Breast Cancer: Results from the BIG 1-98 Trial (Posted: 01/17/2006, Updated: 10/06/2009) - In this large international trial of postmenopausal women treated surgically for early-stage hormone-responsive breast cancer, letrozole did better to prevent a recurrence of disease (especially distant metastases) than the commonly prescribed tamoxifen. Sequential therapy, in which letrozole was followed by tamoxifen or tamoxifen was followed by letrozole, did not improve outcomes over letrozole alone.
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