Clinical Trial Results - Progress in Cancer Care
These summaries highlight recently released results from cancer clinical trials. The findings are significant enough that they are likely to influence your medical care.
The summaries are listed in reverse chronological order. You may also use the navigation tools on the left to search the summaries by keyword or type of cancer.
(Posted: 12/02/2011) - Radiation therapy after breast-conserving surgery substantially reduces the risk of cancer recurring in the breast and moderately reduces the risk of death from the disease, according to updated results from a meta-analysis by the Early Breast Cancer Trialists' Collaborative Group.
Study Shows Aspirin Reduces Colorectal Cancer in Those at High Risk
(Posted: 12/02/2011) - Findings from the first large clinical trial of its kind indicate that taking high doses of aspirin daily for at least 2 years substantially reduces the risk of colorectal cancer among people at increased risk of the disease.
Long-Term Data from 20 Trials Confirm Tamoxifen’s Long-Lasting Benefit
(Posted: 11/23/2011) - In an analysis of data from participants in 20 clinical trials, women with estrogen receptor-positive breast cancer who received about 5 years of adjuvant treatment with tamoxifen had a lower risk of recurrence in the 15 years after starting treatment than women who did not receive tamoxifen.
Smoking Cessation Drug Proves Effective in Single-Center Trial
(Posted: 11/03/2011) - The smoking cessation drug cytisine was more effective than a placebo at helping participants abstain from smoking, according to results of a randomized controlled trial published in the September 29, 2011, issue of the New England Journal of Medicine.
Chemotherapy Less Toxic to the Heart May Be Option for Some Women with HER2-Positive Breast Cancer
(Posted: 11/03/2011) - A nonanthracycline-containing chemotherapy regimen combined with the targeted therapy trastuzumab may be an option for some women with HER2-positive breast cancer, according to results from the Breast Cancer International Research Group 006 (BCIRG-006) trial reported October 6, 2011, in the New England Journal of Medicine.