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Lung Cancer Trial Results

  • Lung cancer trial results show mortality benefit with low-dose CT:
    (Posted: 11/04/2010) - The NCI has released initial results from a large-scale test of screening methods to reduce deaths from lung cancer by detecting cancers at relatively early stages. The National Lung Screening Trial, a randomized national trial involving more than 53,000 current and former heavy smokers ages 55 to 74, compared the effects of two screening procedures for lung cancer -- low-dose helical computed tomography (CT) and standard chest X-ray -- on lung cancer mortality and found 20 percent fewer lung cancer deaths among trial participants screened with low-dose helical CT.
  • Palliative Care Improves Survival, Quality of Life in Advanced Lung Cancer
    (Posted: 09/23/2010) - Patients with advanced lung cancer who received early palliative care experienced longer median survival than those who only received palliative care near death, according to results of a randomized clinical trial published August 19, 2010, in the New England Journal of Medicine.
  • Gefitinib Improves Progression-free Survival for Metastatic Lung Cancers with EGFR Mutations
    (Posted: 08/12/2010) - Patients newly diagnosed with metastatic non-small cell lung cancer (NSCLC) who received gefitinib (Iressa) had significantly higher response rates and longer progression-free survival compared with patients who received carboplatin plus paclitaxel, according to results of a phase III trial conducted in Japan.
  • Long-term Follow-up Provides New Insights on Adjuvant Therapy for Lung Cancer
    (Posted: 12/16/2009) - Longer-term follow-up reports from two large, randomized clinical trials of chemotherapy delivered after surgery in patients with non-small cell lung cancer (NSCLC) have yielded disparate results on the value of such treatment.
  • Radiotherapy Can Prevent Spread of Small-Cell Lung Cancer to the Brain
    (Posted: 06/20/2007, Updated: 01/01/2008) - Radiation therapy to the head, given to patients who had responded to chemotherapy for advanced small-cell lung cancer, reduced by about two-thirds the risk that patients' tumors would spread to the brain, according to findings presented at the 2007 ASCO meeting in Chicago.
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