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Lung Cancer Trial Results


Lung cancer trial results show mortality benefit with low-dose CT:
(Posted: 11/04/2010) - The NCI has released initial results from a large-scale test of screening methods to reduce deaths from lung cancer by detecting cancers at relatively early stages. The National Lung Screening Trial, a randomized national trial involving more than 53,000 current and former heavy smokers ages 55 to 74, compared the effects of two screening procedures for lung cancer -- low-dose helical computed tomography (CT) and standard chest X-ray -- on lung cancer mortality and found 20 percent fewer lung cancer deaths among trial participants screened with low-dose helical CT.

Palliative Care Improves Survival, Quality of Life in Advanced Lung Cancer
(Posted: 09/23/2010) - Patients with advanced lung cancer who received early palliative care experienced longer median survival than those who only received palliative care near death, according to results of a randomized clinical trial published August 19, 2010, in the New England Journal of Medicine.

Gefitinib Improves Progression-free Survival for Metastatic Lung Cancers with EGFR Mutations
(Posted: 08/12/2010) - Patients newly diagnosed with metastatic non-small cell lung cancer (NSCLC) who received gefitinib (Iressa) had significantly higher response rates and longer progression-free survival compared with patients who received carboplatin plus paclitaxel, according to results of a phase III trial conducted in Japan.

Long-term Follow-up Provides New Insights on Adjuvant Therapy for Lung Cancer
(Posted: 12/16/2009) - Longer-term follow-up reports from two large, randomized clinical trials of chemotherapy delivered after surgery in patients with non-small cell lung cancer (NSCLC) have yielded disparate results on the value of such treatment.

No Survival Benefit from Adjuvant Chemo in Stage 1B NSCLC
(Posted: 10/30/2008) - The paclitaxel-plus-carboplatin adjuvant chemotherapy regimen offers no survival benefit to patients with stage 1B non-small-cell lung cancer, according to a report published online September 22, 2008, in the Journal of Clinical Oncology.

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