Basic Trial Information
Trial Description
     Summary
     Further Trial Information
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

Trial Description

Summary

This randomized phase III trial is studying sunitinib malate to see how well it works when given as maintenance therapy compared with a placebo in treating patients with stage III or stage IV non-small cell lung cancer previously treated with combination chemotherapy. Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. It is not yet known whether sunitinib malate is more effective than a placebo in treating non-small cell lung cancer.

Further Study Information

PRIMARY OBJECTIVES:

I. To evaluate the effect of sunitinib (sunitinib malate) compared to placebo on PFS in advanced NSCLC patients who have had either stable or responding disease over the course of their initial 4 cycles of platinum-based therapy.

SECONDARY OBJECTIVES:

I. To evaluate the toxicity of sunitinib compared to placebo in the maintenance setting.

II. To evaluate the additional response rate as a result of sunitinib in this setting.

III. To assess the impact of sunitinib on overall survival compared to the placebo arm.

IV. To assess the impact of sunitinib on delaying the time to deterioration in quality of life and symptom progression compared to placebo using the EORTC QLQ-C30 and LC13.

V. To assess VEGF haplotypes in advanced non-small cell lung cancer and sunitinib maintenance.

OUTLINE: This is a multicenter study. Patients are stratified according to ECOG performance status (0 vs 1), disease stage (IIIB vs IV), prior treatment with bevacizumab (yes vs no), and gender. Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive sunitinib malate orally (PO) once daily on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive placebo PO once daily on days 1-21. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed every 3 months for 1 year, every 6 months for 1 year, and periodically for 3 years.

Eligibility Criteria

Inclusion Criteria:

• Histologic or cytologic documentation of primary non-small cell lung cancer

• Stage IIIB or IV disease patients who are not candidates for combined modality therapy (chemoradiotherapy)

• No evidence of symptomatic or untreated brain metastases, spinal cord compression, or carcinomatous meningitis; patients with central nervous system (CNS) metastases must be asymptomatic, must have received definitive therapy (>= 6 weeks since resection or >= 2 weeks since radiotherapy) for brain metastases, and be off steroids or on a stable dose for 2 weeks prior to registration

• No cavitary lesions

• Patients must have received one chemotherapy regimen for stage IIIB or IV NSCLC; the regimen must include four cycles of platinum-based doublet chemotherapy with or without bevacizumab (bevacizumab may not be given beyond the fourth cycle of chemotherapy); patients must have achieved a complete response, partial response, or stable disease to first-line chemotherapy and have no evidence of disease progression; patients will be registered 3-5 weeks following day 1 of cycle 4 of prior therapy

• No prior adjuvant chemotherapy for stage I-III resected NSCLC or combined modality therapy for stage III NSCLC

• No other primary therapy (including experimental therapy) for NSCLC; palliative radiation therapy must have been completed at least one week before planned start of protocol therapy

• Patients must have measurable or non-measurable disease

• Measurable disease: lesions that can be accurately measured in at least one dimension (longest diameter to be recorded) as >= 2 cm with conventional techniques or as >= 1 cm with spiral CT scan

• Non-measurable disease: all other lesions, including small lesions (longest diameter < 20 mm with conventional techniques or < 10 mm with spiral computed tomography [CT] scan) and truly non-measurable lesions; lesions that are considered non-measurable include the following:

• Bone lesions

• Leptomeningeal disease

• Ascites

• Pleural/pericardial effusion

• Lymphangitis cutis/pulmonis

• Abdominal masses that are not confirmed and followed by imaging techniques

• Cystic lesions

• Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1

• Non-pregnant and non-nursing

• No ongoing cardiac dysrhythmias, atrial fibrillation, or history of corrected QT (QTc) interval >= 500 msec (within 2 years prior to registration); the use of agents with proarrhythmic potential (e.g., quinidine, procainamide, disopyramide, sotalol, probucol, haloperidol, risperidone, indapamide, flecainide) is not recommended while on protocol therapy

• Patients with class I New York Heart Association (NYHA) heart failure are eligible; patients with a history of class II NYHA heart failure are eligible, provided they meet at least one of the following criteria:

• Patients with a history of class II heart failure who are asymptomatic on treatment

• Patients with prior anthracycline exposure

• Patients who have received central thoracic radiation that included the heart in the radiotherapy port

• Patients with a history of class III or IV NYHA heart failure within 12 months prior to registration are not eligible

• No myocardial infarction, severe/unstable angina, coronary/peripheral artery bypass graft or stenting, cerebrovascular accident or transient ischemic attack within the last year

• Patients with hypertension that cannot be controlled by medications (> 150/100 mmHg despite optimal medical therapy) are not eligible

• Patients who require use of therapeutic anticoagulation for thromboembolic disease are not eligible; Note: low doses of coumadin (up to 2 mg daily) are permitted for prophylaxis of thrombosis

• No history of venous thrombosis, pulmonary embolism, or hypercoagulopathy syndrome

• No history of pulmonary hemorrhage, bleeding diathesis, or evidence of hemoptysis; patients with blood-tinged or blood-streaked sputum will be permitted on study if the hemoptysis amounts to less than 5 ml of blood per episode and less than 10 ml of blood per 24-hour period in the best estimate of the investigator

• Patients with a history of hypothyroidism are eligible, provided they are currently euthyroid

• None of the following within 28 days of beginning treatment: abdominal fistula, gastrointestinal perforation, intra-abdominal abscess, serious or non-healing wound, ulcer, or bone fracture

• The following inhibitors of cytochrome P450 3A4 (CYP3A4) are prohibited within 7 days before beginning and during treatment with sunitinib: azole antifungals (ketoconazole, itraconozole), diltiazem, clarithromycin, erythromycin, verapamil, delavirdine, and HIV protease inhibitors (indinavir, saquinavir, ritonavir, atazanavir, nelfinavir); the following inducers of CYP3A4 are prohibited within 12 days before beginning and during treatment with sunitinib: rifampin, rifabutin, carbamazepine, phenobarbital, phenytoin, St. John's Wort, efavirenz, tipranavir; other inhibitors and inducers of CYP3A4 may be used if necessary, but their use is discouraged

• Patients unable to take oral medication are not eligible

• Granulocytes >= 1,500/mcl

• Platelet count >= 100,000/mcl

• Total bilirubin =< 1.5 x upper limit of normal (ULN)

• Aspartate aminotransferase (AST) and alanine aminotransferase (ALT)=< 2.5 x ULN; patients with liver metastases may have AST and ALT =< 5 x ULN; all other patients will have AST and ALT =< 2.5 x ULN

• Creatinine =< 1.5 mg/dl

Trial Contact Information

Trial Lead Organizations/Sponsors

National Cancer Institute

Mark A. Socinski

Principal Investigator

U.S.A.
Arkansas
	Little Rock
	Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
		Rangaswamy Govindarajan	Ph: 501-686-8274
California
	Anaheim
	Kaiser Permanente Medical Center - Anaheim/Orange County
		Han A Koh	Ph: 626-564-3455
	Baldwin Park
	Kaiser Permanente Medical Center - Baldwin Park
		Han A Koh	Ph: 626-564-3455
	Bellflower
	Kaiser Permanente Medical Center - Bellflower
		Han A Koh	Ph: 626-564-3455
	Castro Valley
	East Bay Radiation Oncology Center
		James H. Feusner	Ph: 510-450-7600
	Fairfield
	North Bay Cancer Center
		Brian G Vikstrom	Ph: 707-646-4016
	Fontana
	Kaiser Permanente Medical Center - Fontana
		Han A Koh	Ph: 626-564-3455
	Harbor City
	Kaiser Permanente Medical Center - Harbor City
		Han A Koh	Ph: 626-564-3455
	Irvine
	Kaiser Permanente - Irvine
		Han A Koh	Ph: 626-564-3455
	Long Beach
	Todd Cancer Institute at Long Beach Memorial Medical Center
		Nilesh L Vora	Ph: 562-933-0900
	Los Angeles
	Kaiser Foundation Hospital - West Los Angeles
		Han A Koh	Ph: 626-564-3455
	Kaiser Permanente Medical Center - Los Angeles
		Han A Koh	Ph: 626-564-3455
		Han A Koh	Ph: 626-564-3455
	Martinez
	Contra Costa Regional Medical Center
		James H. Feusner	Ph: 510-450-7600
	Modesto
	Memorial Medical Center
		Jorge A Garcia-Young	Ph: 209-572-7116
	Mountain View
	El Camino Hospital Cancer Center
		James H. Feusner	Ph: 510-450-7600
	Palo Alto Medical Foundation
		Peter P. Yu	Ph: 650-934-7000
	Oakland
	Alta Bates Summit Medical Center - Summit Campus
		James H. Feusner	Ph: 510-450-7600
	Bay Area Breast Surgeons, Incorporated
		James H. Feusner	Ph: 510-450-7600
	CCOP - Bay Area Tumor Institute
		James H. Feusner	Ph: 510-450-7600
	Epic Care - Oakland
		James H. Feusner	Ph: 510-450-7600
	Highland General Hospital
		James H. Feusner	Ph: 510-450-7600
	Larry G Strieff MD Medical Corporation
		James H. Feusner	Ph: 510-450-7600
	Palo Alto
	Palo Alto Medical Foundation
		David S Leibowitz	Ph: 650-853-2906
			Email: waldorj@pamf.org
	Panorama City
	Kaiser Permanente Medical Group
		Han A Koh	Ph: 626-564-3455
	Paradise
	Feather River Hospital Cancer Center
		Sam Mazj	Ph: 530-876-7995
			Email: haleew@ah.org
	Pismo Beach
	Palchak David MD
		David L. Palchak	Ph: 805-474-9143
	Riverside
	Kaiser Permanente Medical Center - Riverside
		Han A Koh	Ph: 626-564-3455
	Saint Helena
	Saint Helena Hospital
		Gregory B Smith	Ph: 707-967-3698
	San Diego
	Kaiser Permanente - Mission
		Han A Koh	Ph: 626-564-3455
	Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego
		Han A Koh	Ph: 626-564-3455
	Kaiser Permanente Medical Office -Vandever Medical Office
		Han A Koh	Ph: 626-564-3455
	Naval Medical Center - San Diego
		Preston S. Gable	Ph: 619-532-8712
	San Marcos
	Kaiser Permanente Health Care
		Han A Koh	Ph: 626-564-3455
	San Pablo
	Doctors Medical Center - San Pablo Campus
		James H. Feusner	Ph: 510-450-7600
	Woodland Hills
	Kaiser Permanente Medical Cener - Woodland Hills
		Han A Koh	Ph: 626-564-3455
Colorado
	Fort Collins
	Front Range Cancer Specialists
		Robert F Marschke	Ph: 970-482-3328
	Poudre Valley Hospital
		Paolo Romero	Ph: 970-495-8226
Connecticut
	Hartford
	Helen and Harry Gray Cancer Center at Hartford Hospital
		Robert D. Siegel	Ph: 860-545-5363
	Middletown
	Middlesex Hospital Cancer Center
		Susanna Hong	Ph: 860-358-2058
	New Britain
	George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus
		Brian J Byrne	Ph: 860-224-5660
Delaware
	Lewes
	Tunnell Cancer Center at Beebe Medical Center
		Stephen Scott Grubbs	Ph: 302-733-6227
	Newark
	Helen F. Graham Cancer Center at Christiana Hospital
		Stephen Scott Grubbs	Ph: 302-733-6227
District of Columbia
	Washington
	Sibley Memorial Hospital
		Frederick Pearson Smith	Ph: 202-243-2373
Florida
	Daytona Beach
	Florida Hospital Memorial Medical Center
		Seema Harichand-Herdt	Ph: 386-676-6025
	Fort Lauderdale
	Broward General Medical Center Cancer Center
		Barry S Berman	Ph: 954-355-5346
	Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
		Estelamari Rodriguez	Ph: 305-674-2625
			Email: info@msccop.com
	Jupiter
	Ella Milbank Foshay Cancer Center at Jupiter Medical Center
		Estelamari Rodriguez	Ph: 305-674-2625
			Email: info@msccop.com
	Miami Beach
	CCOP - Mount Sinai Medical Center
		Estelamari Rodriguez	Ph: 305-674-2625
			Email: info@msccop.com
	Orlando
	Florida Hospital Cancer Institute at Florida Hospital Orlando
		Lee M. Zehngebot	Ph: 407-303-5623
Georgia
	Columbus
	John B. Amos Cancer Center
		Andrew W. Pippas	Ph: 706-660-6404
	Savannah
	Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
		Harvey C. Lebos	Ph: 912-350-8568
	Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
		Mark A. Taylor	Ph: 912-350-8568
Illinois
	Alton
	Saint Anthony's Hospital at Saint Anthony's Health Center
		Bethany G. Sleckman	Ph: 913-948-5588
	Aurora
	Rush-Copley Cancer Care Center
		Kendrith M. Rowland	Ph: 800-446-5532
	Chicago
	Creticos Cancer Center at Advocate Illinois Masonic Medical Center
		Deepti A. Singh	Ph: 773-296-5360
	Mount Sinai Hospital Medical Center
		Pam G. Khosla	Ph: 773-257-5960
			Email: suhi@sinai.org
	Saint Joseph Hospital
		Ira Oliff	Ph: 312-695-1301
			Email: cancer@northwestern.edu
	Swedish Covenant Hospital
		K. Joseph Philip	Ph: 773-878-8200
	University of Chicago Cancer Research Center
		Michael L Maitland	Ph: 773-834-7424
	Decatur
	Decatur Memorial Hospital Cancer Care Institute
		James L. Wade	Ph: 217-876-4740
			Email: kcheek@dmhhs.org
	Elk Grove Village
	Cancer Institute at Alexian Brothers
		Gary Gordon	Ph: 847-952-7164
			Email: fredianc@alexian.net
	Elmhurst
	Elmhurst Memorial Hospital
		Robert M Eisner	Ph: 630-352-5300
	Evanston
	CCOP - Evanston
		Thomas Hensing	Ph: 847-570-1381
	St. Francis Hospital
		K. Joseph Philip	Ph: 773-878-8200
	Kankakee
	Provena St. Mary's Regional Cancer Center - Kankakee
		Riaz Elahi	Ph: 888-823-5923
			Email: ctsucontact@westat.com
	La Grange
	La Grange Memorial Hospital
		James E. Hannigan	Ph: 800-323-8622
	Moline
	Garneau, Stewart C MD (UIA Investigator)
		Costas L. Constantinou	Ph: 319-363-2690
	Porubcin, Michael MD (UIA Investigator)
		Costas L. Constantinou	Ph: 319-363-2690
	Spector, David MD (UIA Investigator)
		Costas L. Constantinou	Ph: 319-363-2690
	Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
		Costas L. Constantinou	Ph: 319-363-2690
	Mt. Vernon
	Good Samaritan Regional Health Center
		Bethany G. Sleckman	Ph: 913-948-5588
	Naperville
	Hematology Oncology Consultants - Naperville
		Fariborze Behram Barhamand	Ph: 630-369-1501
	Rockford
	Swedish-American Regional Cancer Center
		Harvey Eric Einhorn	Ph: 815-489-4413
	Urbana
	Carle Cancer Center at Carle Foundation Hospital
		Kendrith M. Rowland	Ph: 800-446-5532
Indiana
	Elkhart
	Elkhart Clinic, LLC
		Rafat H. Ansari	Ph: 574-234-5123
	Elkhart General Hospital
		Rafat H. Ansari	Ph: 574-234-5123
	Michiana Hematology-Oncology, PC - Elkhart
		Rafat H. Ansari	Ph: 574-234-5123
	Fort Wayne
	Fort Wayne Medical Oncology and Hematology
		Sreenivasa Rao Nattam	Ph: 260-484-8830
			Email: ledgar@fwmoh.com
	Indianapolis
	St. Vincent Indianapolis Hospital
		Ruemu E Birhiray	Ph: 317-338-2194
	Kokomo
	Community Cancer Care at Howard Regional Health System
		Rafat H. Ansari	Ph: 574-234-5123
	La Porte
	Center for Cancer Therapy at LaPorte Hospital and Health Services
		Rafat H. Ansari	Ph: 574-234-5123
	Michigan City
	Saint Anthony Memorial Health Centers
		Kendrith M. Rowland	Ph: 800-446-5532
	Mishawaka
	Michiana Hematology-Oncology, PC - Mishawaka
		Rafat H. Ansari	Ph: 574-234-5123
	Saint Joseph's Medical Center
		Rafat H. Ansari	Ph: 574-234-5123
	Plymouth
	Michiana Hematology Oncology PC - Plymouth
		Rafat H. Ansari	Ph: 574-234-5123
	South Bend
	CCOP - Northern Indiana CR Consortium
		Rafat H. Ansari	Ph: 574-234-5123
	Memorial Hospital of South Bend
		Rafat H. Ansari	Ph: 574-234-5123
	Michiana Hematology-Oncology, PC - South Bend
		Rafat H. Ansari	Ph: 574-234-5123
	Westville
	Michiana Hematology Oncology-PC Westville
		Rafat H. Ansari	Ph: 574-234-5123
Iowa
	Bettendorf
	Constantinou, Costas L MD (UIA Investigator)
		Costas L. Constantinou	Ph: 319-363-2690
	Cedar Rapids
	Cedar Rapids Oncology Associates
		Deborah W Wilbur	Ph: 319-363-2690
		Deborah W Wilbur	Ph: 319-363-2690
	Mercy Regional Cancer Center at Mercy Medical Center
		Deborah W Wilbur	Ph: 319-363-2690
	Des Moines
	CCOP - Iowa Oncology Research Association
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	John Stoddard Cancer Center at Iowa Lutheran Hospital
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	John Stoddard Cancer Center at Iowa Methodist Medical Center
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Medical Oncology and Hematology Associates at John Stoddard Cancer Center
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Medical Oncology and Hematology Associates at Mercy Cancer Center
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Mercy Cancer Center at Mercy Medical Center - Des Moines
		Robert J Behrens	Ph: 888-244-6061
			Email: sherrijr@iora.org
	Iowa City
	Holden Comprehensive Cancer Center at University of Iowa
		Daniel A Vaena	Ph: 800-237-1225
	Veterans Affairs Medical Center - Iowa City
		Daniel A Vaena	Ph: 800-237-1225
	Mason City
	Mercy Cancer Center at Mercy Medical Center - North Iowa
		Arvind Y Vemula	Ph: 800-433-3883
	Sioux City
	Mercy Medical Center - Sioux City
		Donald Bruce Wender	Ph: 712-252-0088
	Siouxland Hematology-Oncology Associates, LLP
		Donald Bruce Wender	Ph: 712-252-0088
	St. Luke's Regional Medical Center
		Donald Bruce Wender	Ph: 712-252-0088
Kansas
	Chanute
	Cancer Center of Kansas, PA - Chanute
		Shaker R. Dakhil	Ph: 316-262-4467
	Dodge City
	Cancer Center of Kansas, PA - Dodge City
		Shaker R. Dakhil	Ph: 316-262-4467
	El Dorado
	Cancer Center of Kansas, PA - El Dorado
		Shaker R. Dakhil	Ph: 316-262-4467
	Fort Scott
	Cancer Center of Kansas - Fort Scott
		Shaker R. Dakhil	Ph: 316-262-4467
	Independence
	Cancer Center of Kansas-Independence
		Shaker R. Dakhil	Ph: 316-262-4467
	Kansas City
	Providence Medical Center
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Kingman
	Cancer Center of Kansas, PA - Kingman
		Shaker R. Dakhil	Ph: 316-262-4467
	Lawrence
	Lawrence Memorial Hospital
		Shaker R. Dakhil	Ph: 316-262-4467
	Liberal
	Cancer Center of Kansas, PA - Liberal
		Shaker R. Dakhil	Ph: 316-262-4467
	McPherson
	Cancer Center of Kansas, PA - McPherson
		Shaker R. Dakhil	Ph: 316-262-4467
	Newton
	Cancer Center of Kansas, PA - Newton
		Shaker R. Dakhil	Ph: 316-262-4467
	Overland Park
	Menorah Medical Center
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Luke's Hospital - South
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Parsons
	Cancer Center of Kansas, PA - Parsons
		Shaker R. Dakhil	Ph: 316-262-4467
	Prairie Village
	CCOP - Kansas City
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Pratt
	Cancer Center of Kansas, PA - Pratt
		Shaker R. Dakhil	Ph: 316-262-4467
	Salina
	Cancer Center of Kansas, PA - Salina
		Shaker R. Dakhil	Ph: 316-262-4467
	Topeka
	Cotton-O'Neil Cancer Center
		David E Einspahr	Ph: 785-270-4963
	Wellington
	Cancer Center of Kansas, PA - Wellington
		Shaker R. Dakhil	Ph: 316-262-4467
	Wichita
	Associates in Women's Health, PA - North Hillside
		Shaker R. Dakhil	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Medical Arts Tower
		Shaker R. Dakhil	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Wichita
		Shaker R. Dakhil	Ph: 316-262-4467
	CCOP - Wichita
		Shaker R. Dakhil	Ph: 316-262-4467
	Via Christi Cancer Center at Via Christi Regional Medical Center
		Shaker R. Dakhil	Ph: 316-262-4467
	Winfield
	Cancer Center of Kansas, PA - Winfield
		Shaker R. Dakhil	Ph: 316-262-4467
Louisiana
	Baton Rouge
	Hematology-Oncology Clinic
		Hana F Safah	Ph: 504-988-6121
	Mary Bird Perkins Cancer Center - Baton Rouge
		Robert W Veith	Ph: 504-568-3410
			Email: aconne1@lsuhsc.edu
	Pennington Cancer Center at Baton Rouge General
		Robert W Veith	Ph: 504-568-3410
			Email: aconne1@lsuhsc.edu
	New Orleans
	Medical Center of Louisiana - New Orleans
		Robert W Veith	Ph: 504-568-3410
			Email: aconne1@lsuhsc.edu
	Stanley S. Scott Cancer Center at Louisiana State University Medical Center - New Orleans
		Robert W Veith	Ph: 504-568-3410
			Email: aconne1@lsuhsc.edu
	Tulane Cancer Center at Tulane University Hospital and Clinic
		Hana F Safah	Ph: 504-988-6121
Maryland
	Baltimore
	Greenebaum Cancer Center at University of Maryland Medical Center
		Martin J. Edelman	Ph: 800-888-8823
	Veterans Affairs Medical Center - Baltimore
		Martin J. Edelman	Ph: 800-888-8823
	Bel Air
	Upper Chesapeake Medical Center
		Martin J. Edelman	Ph: 800-888-8823
	Elkton MD
	Union Hospital of Cecil County
		Stephen Scott Grubbs	Ph: 302-733-6227
Massachusetts
	Attleboro
	Sturdy Memorial Hospital
		Colleen K Yavarow	Ph: 508-236-7059
	Gloucester
	Addison Gilbert Hospital
		Angus P. McIntyre	Ph: 978-283-4000ext559
Michigan
	Adrian
	Hickman Cancer Center at Bixby Medical Center
		Rex B Mowat	Ph: 517-265-0116
		Rex B Mowat	Ph: 517-265-0116
	Escanaba
	Green Bay Oncology, Limited - Escanaba
		Anthony J. Jaslowski	Ph: 800-432-6049
	Iron Mountain
	Green Bay Oncology - Iron Mountain
		Anthony J. Jaslowski	Ph: 800-432-6049
	Kalamazoo
	Borgess Medical Center
		Raymond Sterling Lord	Ph: 269-373-7458
	Bronson Methodist Hospital
		Raymond Sterling Lord	Ph: 269-373-7458
	West Michigan Cancer Center
		Raymond Sterling Lord	Ph: 269-373-7458
	Monroe
	Community Cancer Center of Monroe
		Rex B Mowat	Ph: 517-265-0116
	Mercy Memorial Hospital - Monroe
		Rex B Mowat	Ph: 517-265-0116
	Royal Oak
	William Beaumont Hospital - Royal Oak Campus
		Matthew B Cotant	Ph: 248-551-7695
	Saint Joseph
	Lakeside Cancer Specialists, PLLC
		Rafat H. Ansari	Ph: 574-234-5123
	Southfield
	Providence Hospital - Southfield
		Anibal Drelichman	Ph: 248-849-5337
			Email: jaswinder.grewal@stjohn.org
	St. Joseph
	Lakeland Regional Cancer Care Center - St. Joseph
		Rafat H. Ansari	Ph: 574-234-5123
Minnesota
	Burnsville
	Fairview Ridges Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Coon Rapids
	Mercy and Unity Cancer Center at Mercy Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Duluth
	CCOP - Duluth
		Daniel Nikcevich	Ph: 888-203-7267
	Essentia Health - Duluth Clinic
		Daniel Nikcevich	Ph: 888-203-7267
	Miller - Dwan Medical Center
		Daniel Nikcevich	Ph: 888-203-7267
	St. Luke's Hospital Cancer Care Center
		Tanya L. Repka	Ph: 888-823-5923
			Email: ctsucontact@westat.com
	Edina
	Fairview Southdale Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Fridley
	Mercy and Unity Cancer Center at Unity Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Hutchinson
	Hutchinson Area Health Care
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Mankato
	Immanuel St. Joseph's
		Mohmmad J Ranginwala	Ph: 507-385-2929
	Maplewood
	HealthEast Cancer Care at St. John's Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Minnesota Oncology - Maplewood
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Minneapolis
	Hennepin County Medical Center - Minneapolis
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Veterans Affairs Medical Center - Minneapolis
		Sharon D Luikart	Ph: 612-467-2800
	Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	New Ulm
	New Ulm Medical Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Robbinsdale
	Humphrey Cancer Center at North Memorial Outpatient Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Saint Louis Park
	CCOP - Metro-Minnesota
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Park Nicollet Cancer Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Saint Paul
	Regions Hospital Cancer Care Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	United Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Shakopee
	St. Francis Cancer Center at St. Francis Medical Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Stillwater
	Lakeview Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Waconia
	Ridgeview Medical Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Willmar
	Willmar Cancer Center at Rice Memorial Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Woodbury
	Minnesota Oncology - Woodbury
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
Mississippi
	Gulfport
	Memorial Hospital at Gulfport
		Robert W Veith	Ph: 504-568-3410
			Email: aconne1@lsuhsc.edu
	Pascagoula
	Regional Cancer Center at Singing River Hospital
		James E. Clarkson	Ph: 228-809-5292
Missouri
	Cape Girardeau
	Saint Francis Medical Center
		Bethany G. Sleckman	Ph: 913-948-5588
	Southeast Cancer Center
		Alan Philip Lyss	Ph: 800-392-0936
	Chesterfield
	Saint Luke's Hospital
		Donald F. Busiek	Ph: 314-205-6936
	Columbia
	Ellis Fischel Cancer Center at University of Missouri - Columbia
		Carl E. Freter	Ph: 573-882-7440
	Veterans Affairs Medical Center - Columbia (Truman Memorial)
		Shadi M Haddadin
			Email: calgbco@calgb.org
	Jefferson City
	Goldschmidt Cancer Center
		Alan Philip Lyss	Ph: 800-392-0936
	Kansas City
	Heartland Hematology Oncology Associates, Incorporated
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	North Kansas City Hospital
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Parvin Radiation Oncology
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Research Medical Center
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Luke's Hospital
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Lee's Summit
	Saint Luke's East - Lee's Summit
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Joseph
	Heartland Regional Medical Center
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Joseph Oncology, Incorporated
		Rakesh Gaur	Ph: 913-948-5588
			Email: amy.krushelniski@hcahealthcare.com
	Saint Louis
	CCOP - St. Louis-Cape Girardeau
		Bethany G. Sleckman	Ph: 913-948-5588
	David C. Pratt Cancer Center at St. John's Mercy
		Bethany G. Sleckman	Ph: 913-948-5588
	Mercy Clinic St. Louis Cancer and Breast Institute
		Bethany G. Sleckman	Ph: 913-948-5588
	Missouri Baptist Cancer Center
		Alan Philip Lyss	Ph: 800-392-0936
	Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
		Maria Q. Baggstrom	Ph: 800-600-3606
			Email: info@siteman.wustl.edu
Nebraska
	Lincoln
	Cancer Resource Center - Lincoln
		Gamini S. Soori	Ph: 800-253-4368
	Omaha
	Alegant Health Cancer Center at Bergan Mercy Medical Center
		Gamini S. Soori	Ph: 800-253-4368
	CCOP - Missouri Valley Cancer Consortium
		Gamini S. Soori	Ph: 800-253-4368
	Creighton University Medical Center
		Gamini S. Soori	Ph: 800-253-4368
	Immanuel Medical Center
		Gamini S. Soori	Ph: 800-253-4368
	Lakeside Hospital
		Gamini S. Soori	Ph: 800-253-4368
	Methodist Estabrook Cancer Center
		Robert M. Langdon	Ph: 402-354-5144
Nevada
	Las Vegas
	CCOP - Nevada Cancer Research Foundation
		John Allan Ellerton	Ph: 702-731-8274
	University Medical Center of Southern Nevada
		John Allan Ellerton	Ph: 702-731-8274
New Hampshire
	Concord
	New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
		Frederick M. Briccetti	Ph: 800-339-6484
	Exeter
	Center for Cancer Care at Exeter Hospital
		Michael S Buff	Ph: 800-339-6484
	Hooksett
	New Hampshire Oncology - Hematology, PA - Hooksett
		Frederick M. Briccetti	Ph: 800-339-6484
	Laconia
	Lakes Region General Hospital
		Frederick M. Briccetti	Ph: 800-339-6484
New Jersey
	Camden
	Cancer Institute of New Jersey at Cooper University Hospital - Camden
		Stephen Scott Grubbs	Ph: 302-733-6227
	East Orange
	Veterans Affairs Medical Center - East Orange
		Basil S. Kasimis	Ph: 800-475-2336
			Email: patricia.goyer@med.va.gov
	Newark
	Newark Beth Israel Medical Center
		Lori Schleicher	Ph: 973-926-7230
	Toms River
	J. Phillip Citta Regional Cancer Center at Community Medical Center
		Sudha Kavuru	Ph: 732-818-3882
	Vineland
	Frank and Edith Scarpa Regional Cancer Pavillion at South Jersey Healthcare
		Carl J. Minniti	Ph: 856-641-7933
New York
	Cooperstown
	Bassett Healthcare Regional Cancer Program at Mary Imogene Bassett Hospital
		Eric Bravin	Ph: 607-547-6965
			Email: jennifer.victory@bassett.org
	East Syracuse
	CCOP - Hematology-Oncology Associates of Central New York
		Jeffrey J. Kirshner	Ph: 315-472-7504
	Glens Falls
	Charles R. Wood Cancer Center at Glens Falls Hospital
		Aqeel A Gillani	Ph: 518-926-6700
	Middletown
	Tucker Center for Cancer Care at Orange Regional Medical Center
		Jeffrey M. Stewart	Ph: 845-342-7609
	Syracuse
	SUNY Upstate Medical University Hospital
		Stephen L. Graziano	Ph: 315-464-5476
	Veterans Affairs Medical Center - Syracuse
		Ajeet Gajra	Ph: 315-425-2707
North Carolina
	Burlington
	Alamance Cancer Center at Alamance Regional Medical Center
		Sandeep R Pandit	Ph: 336-538-7725
	Chapel Hill
	Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
		Jared Weiss	Ph: 877-668-0683
	Durham
	Duke Cancer Institute
		Jeffrey Crawford	Ph: 888-275-3853
	Veterans Affairs Medical Center - Durham
		Sally J York	Ph: 800-811-8480
	Goldsboro
	Wayne Memorial Hospital, Incorporated
		James N. Atkins	Ph: 919-580-0000
	Hendersonville
	Comprehensive Cancer Center at Pardee Hospital
		James E. Radford	Ph: 828-696-4716
	Kinston
	Kinston Medical Specialists
		Peter R. Watson	Ph: 252-559-2200
	Lumberton
	Southeastern Regional Medical Center
		Jeffrey Crawford	Ph: 888-275-3853
	Oxford
	Granville Medical Center
		Jeffrey Crawford	Ph: 888-275-3853
	Raleigh
	Duke Health Raleigh Hospital
		Jeffrey Crawford	Ph: 888-275-3853
	Rocky Mount
	Nash Hospitals, Incorporated
		Jared Weiss	Ph: 877-668-0683
	Roxboro
	Person Memorial Hospital
		Jeffrey Crawford	Ph: 888-275-3853
	Winston-Salem
	Wake Forest University Comprehensive Cancer Center
		Antonius A. Miller	Ph: 336-713-6771
North Dakota
	Bismarck
	Bismarck Cancer Center
		Edward J. Wos	Ph: 701-323-5760
			Email: tfischer@mohs.org
	Medcenter One Hospital Cancer Care Center
		Edward J. Wos	Ph: 701-323-5760
			Email: tfischer@mohs.org
	Mid Dakota Clinic, PC
		Edward J. Wos	Ph: 701-323-5760
			Email: tfischer@mohs.org
	St. Alexius Medical Center Cancer Center
		Edward J. Wos	Ph: 701-323-5760
			Email: tfischer@mohs.org
	Fargo
	Dakota Cancer Institute at Dakota Clinic - South University
		Daniel Nikcevich	Ph: 888-203-7267
	Grand Forks
	Altru Cancer Center at Altru Hospital
		Grant R Seeger	Ph: 701-780-6520
Ohio
	Akron
	McDowell Cancer Center at Akron General Medical Center
		Esther H. Rehmus	Ph: 330-344-6348
	Bowling Green
	Wood County Oncology Center
		Rex B Mowat	Ph: 517-265-0116
	Canton
	Mercy Cancer Center at Mercy Medical Center
		Mitchell Haut	Ph: 888-293-4673
	Chillicothe
	Adena Regional Medical Center
		J. Philip Kuebler	Ph: 502-361-8496
	Cleveland
	MetroHealth Cancer Care Center at MetroHealth Medical Center
		Bruce J. Averbook	Ph: 216-778-8526
			Email: kbauchens@metrohealth.org
	Columbus
	Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center
		Gregory A. Otterson	Ph: 866-627-7616
			Email: osu@emergingmed.com
	CCOP - Columbus
		J. Philip Kuebler	Ph: 502-361-8496
	Doctors Hospital at Ohio Health
		J. Philip Kuebler	Ph: 502-361-8496
	Grant Medical Center Cancer Care
		J. Philip Kuebler	Ph: 502-361-8496
	Mount Carmel Health - West Hospital
		J. Philip Kuebler	Ph: 502-361-8496
	Riverside Methodist Hospital Cancer Care
		J. Philip Kuebler	Ph: 502-361-8496
	Zangmeister Center
		J. Philip Kuebler	Ph: 502-361-8496
	Delaware
	Grady Memorial Hospital
		J. Philip Kuebler	Ph: 614-566-3275
	Elyria
	Hematology Oncology Center
		Rex B Mowat	Ph: 517-265-0116
	Lancaster
	Fairfield Medical Center
		J. Philip Kuebler	Ph: 502-361-8496
	Lima
	Lima Memorial Hospital
		Rex B Mowat	Ph: 517-265-0116
	St. Rita's Medical Center
		Henry Gerad	Ph: 419-226-9617
	Marietta
	Strecker Cancer Center at Marietta Memorial Hospital
		J. Philip Kuebler	Ph: 502-361-8496
	Maumee
	Northwest Ohio Oncology Center
		Rex B Mowat	Ph: 517-265-0116
		Rex B Mowat	Ph: 517-265-0116
	Mount Vernon
	Knox Community Hospital
		J. Philip Kuebler	Ph: 502-361-8496
	Newark
	Licking Memorial Cancer Care Program at Licking Memorial Hospital
		J. Philip Kuebler	Ph: 502-361-8496
	Oregon
	St. Charles Mercy Hospital
		Rex B Mowat	Ph: 517-265-0116
	Toledo Clinic - Oregon
		Rex B Mowat	Ph: 517-265-0116
	Portsmouth
	Southern Ohio Medical Center Cancer Center
		J. Philip Kuebler	Ph: 502-361-8496
	Springfield
	Community Hospital of Springfield and Clark County
		J. Philip Kuebler	Ph: 502-361-8496
	Steubenville
	UPMC Cancer Center at Terarama Cancer Center
		Mark A. Socinski	Ph: 412-647-8073
	Sylvania
	Flower Hospital Cancer Center
		Rex B Mowat	Ph: 517-265-0116
	Tiffin
	Mercy Hospital of Tiffin
		Rex B Mowat	Ph: 517-265-0116
	Toledo
	CCOP - Toledo Community Hospital
		Rex B Mowat	Ph: 517-265-0116
	St. Anne Mercy Hospital
		Rex B Mowat	Ph: 517-265-0116
	St. Vincent Mercy Medical Center
		Rex B Mowat	Ph: 517-265-0116
	Toledo Clinic, Incorporated - Main Clinic
		Rex B Mowat	Ph: 517-265-0116
	Toledo Hospital
		Rex B Mowat	Ph: 517-265-0116
	University of Toledo Medical Center
		Rex B Mowat	Ph: 517-265-0116
	Wauseon
	Fulton County Health Center
		Rex B Mowat	Ph: 517-265-0116
	Westerville
	Mount Carmel St. Ann's Cancer Center
		J. Philip Kuebler	Ph: 502-361-8496
	Zanesville
	Genesis - Good Samaritan Hospital
		J. Philip Kuebler	Ph: 502-361-8496
Oklahoma
	Lawton
	Cancer Centers of Southwest Oklahoma, LLC - Lawton
		Nadim F. Nimeh	Ph: 877-231-4440
	Norman
	Cancer Care Associates - Norman
		Vikki Ann Canfield
			Email: calgbco@calgb.org
	Oklahoma City
	Oklahoma University Cancer Institute
		Shubham Pant	Ph: 405-271-4272
			Email: julie-traylor@ouhsc.edu
Oregon
	Clackamas
	Clackamas Radiation Oncology Center
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Coos Bay
	Bay Area Hospital
		Bret A. Cook	Ph: 541-269-8392
			Email: cherie.cox@bayareahospital.org
	Milwaukie
	Providence Milwaukie Hospital
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Newberg
	Providence Newberg Medical Center
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Oregon City
	Willamette Falls Hospital
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Portland
	CCOP - Columbia River Oncology Program
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Providence Cancer Center at Providence Portland Medical Center
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Providence St. Vincent Medical Center
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Salem
	Salem Hospital Regional Cancer Care Services
		Edward Peter Orlowski	Ph: 503-561-2618
Pennsylvania
	Danville
	Geisinger Cancer Institute at Geisinger Health
		Rajiv Panikkar	Ph: 570-271-5251
	Hazleton
	Geisinger Hazleton Cancer Center
		Rajiv Panikkar	Ph: 570-271-5251
	Philadelphia
	Temple Cancer Center at Temple University Hospital
		Deric C Savior	Ph: 215-728-2983
	Pittsburgh
	UPMC Cancer Centers
		Mark A. Socinski	Ph: 877-668-0683
	Scranton
	Mercy Hospital Cancer Center - Scranton
		Martin B. Hyzinski	Ph: 570-558-3020
	Scranton Hematology Oncology
		Martin B. Hyzinski	Ph: 570-558-3020
	State College
	Geisinger Medical Group - Scenery Park
		Rajiv Panikkar	Ph: 570-271-5251
	West Chester
	Cancer Center of Chester County
		William E. Luginbuhl	Ph: 610-431-5297
	Wilkes-Barre
	Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
		Rajiv Panikkar	Ph: 570-271-5251
Rhode Island
	Pawtucket
	Memorial Hospital of Rhode Island
		Anthony G. Thomas	Ph: 401-729-2700
	Providence
	Miriam Hospital
		William M. Sikov	Ph: 401-793-2224
	Rhode Island Hospital Comprehensive Cancer Center
		William M. Sikov	Ph: 401-793-2224
South Carolina
	Beaufort
	Keyserling Cancer Center at Beaufort Memorial Hospital
		Majd Chahin	Ph: 843-522-7819
	Charleston
	Roper St. Francis Cancer Center at Roper Hospital
		James Michael Orcutt	Ph: 843-720-8386
			Email: elizabeth.strojny@roperstfrancis.com
	Easley
	Cancer Centers of the Carolinas - Easley
		Jeffrey Kent Giguere	Ph: 864-241-6251
	Florence
	McLeod Regional Medical Center
		Rajesh Bajaj	Ph: 843-679-7256
	Greenville
	Cancer Centers of the Carolinas - Faris Road
		Jeffrey Kent Giguere	Ph: 864-241-6251
	Cancer Centers of the Carolinas - Grove Commons
		Jeffrey Kent Giguere	Ph: 864-241-6251
	CCOP - Greenville
		Jeffrey Kent Giguere	Ph: 864-241-6251
	Greer
	Cancer Centers of the Carolinas - Greer Medical Oncology
		Jeffrey Kent Giguere	Ph: 864-241-6251
	Seneca
	Cancer Centers of the Carolinas - Seneca
		Jeffrey Kent Giguere	Ph: 864-241-6251
	Spartanburg
	Cancer Centers of the Carolinas - Spartanburg
		Jeffrey Kent Giguere	Ph: 864-241-6251
South Dakota
	Rapid City
	Rapid City Regional Hospital
		Mark T Schroeder	Ph: 605-716-3982
			Email: research@rcrh.org
	Sioux Falls
	Sanford Cancer Center at Sanford USD Medical Center
		Miroslaw A Mazurczak	Ph: 605-328-1367
		Miroslaw A Mazurczak	Ph: 605-328-1367
Tennessee
	Nashville
	MBCCOP - Meharry Medical College - Nashville
		John J Murray	Ph: 615-327-5724
			Email: jmurray@mmc.edu
Texas
	Houston
	Ben Taub General Hospital
		Martha P Mims	Ph: 713-798-1354
			Email: burton@bcm.edu
	Dan L. Duncan Cancer Center at Baylor College of Medicine
		Martha P Mims	Ph: 713-798-1354
			Email: burton@bcm.edu
	St. Luke's Texas Cancer Institute at St. Luke's Episcopal Hospital
		Martha P Mims	Ph: 713-798-1354
			Email: burton@bcm.edu
	Veterans Affairs Medical Center - Houston
		Martha P Mims	Ph: 713-798-1354
			Email: burton@bcm.edu
	Temple
	Scott and White Cancer Institute
		Lucas Wong	Ph: 254-724-5407
Vermont
	Berlin
	Mountainview Medical
		Steven M. Grunberg	Ph: 802-656-8990
	Burlington
	Vermont Cancer Center at University of Vermont
		Steven M. Grunberg	Ph: 802-656-8990
Virginia
	Danville
	Danville Regional Medical Center
		Timothy W. Brotherton	Ph: 434-793-0044
	Fredericksburg
	Fredericksburg Oncology Inc
		Rex B Mowat	Ph: 517-265-0116
	Lynchburg
	Lynchburg Hematology-Oncology Clinic
		John Leach MacNeill	Ph: 434-200-5925
	Martinsville
	Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County
		Arthur Sleeper	Ph: 276-666-7827
	Richmond
	Virginia Commonwealth University Massey Cancer Center
		Sherman Baker	Ph: 804-628-1939
Washington
	Vancouver
	Southwest Washington Medical Center Cancer Center
		Janet C Ruzich	Ph: 503-216-6260
			Email: orcropregadmin@providence.org
	Yakima
	North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
		Vicky Eileen Jones	Ph: 877-902-3324
West Virginia
	Huntington
	Edwards Comprehensive Cancer Center at Cabell Huntington Hospital
		Maria-Rosalia B. Tria Tirona	Ph: 304-399-6617
	St. Mary's Regional Cancer Center at St. Mary's Medical Center
		Arvinder S Bir	Ph: 888-823-5923
			Email: ctsucontact@westat.com
	Morgantown
	Mary Babb Randolph Cancer Center at West Virginia University Hospitals
		Mohammed Almubarak	Ph: 304-293-2745
			Email: sfilburn@hsc.wvu.edu
	Parkersburg
	Community Comprehensive Cancer Center at Camden-Clark Memorial Hospital
		Nik M. Shah	Ph: 304-424-2585
Wisconsin
	Chippewa Falls
	Marshfield Clinic - Chippewa Center
		Adedayo Onitilo	Ph: 715-393-1400
	Eau Claire
	Marshfield Clinic Cancer Care at Regional Cancer Center
		Adedayo Onitilo	Ph: 715-393-1400
	Fond Du Lac
	Central Wisconsin Cancer Program at Agnesian HealthCare
		Sayeh M Lavasani	Ph: 313-576-9363
	Green Bay
	Green Bay Oncology, Limited at St. Mary's Hospital
		Anthony J. Jaslowski	Ph: 800-432-6049
	Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
		Anthony J. Jaslowski	Ph: 800-432-6049
	St. Vincent Hospital Regional Cancer Center
		Anthony J. Jaslowski	Ph: 800-432-6049
	Janesville
	Mercy Regional Cancer Center
		Robert Delaune	Ph: 800-928-1103
	La Crosse
	Gundersen Lutheran Center for Cancer and Blood
		Kurt Oettel	Ph: 608-775-2385
			Email: cancerctr@gundluth.org
	Madison
	Dean Hematology & Oncology Clinic
		Amit Sanyal	Ph: 608-410-2700
	Manitowoc
	Holy Family Memorial Medical Center Cancer Care Center
		Anthony J. Jaslowski	Ph: 800-432-6049
	Marinette
	Bay Area Cancer Care Center at Bay Area Medical Center
		Anthony J. Jaslowski	Ph: 800-432-6049
	Marshfield
	Marshfield Clinic - Marshfield Center
		Adedayo Onitilo	Ph: 715-393-1400
	Saint Joseph's Hospital
		Adedayo Onitilo	Ph: 715-393-1400
	Mequon
	Columbia Saint Mary's Hospital - Ozaukee
		Charles H. I. Tiber	Ph: 414-326-2675
			Email: clinicaltrials@columbia-stmarys.org
	Milwaukee
	Columbia-Saint Mary's Cancer Care Center
		Charles H. I. Tiber	Ph: 414-326-2675
			Email: clinicaltrials@columbia-stmarys.org
	Minocqua
	Marshfield Clinic - Lakeland Center
		Adedayo Onitilo	Ph: 715-393-1400
	New Richmond
	Cancer Center of Western Wisconsin
		Joseph W Leach	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Oconomowoc
	Regional Cancer Center at Oconomowoc Memorial Hospital
		Michael A Thompson	Ph: 262-928-7632
	Oconto Falls
	Green Bay Oncology, Limited - Oconto Falls
		Anthony J. Jaslowski	Ph: 800-432-6049
	Racine
	All Saints Cancer Center at Wheaton Franciscan Healthcare
		Young M Choi	Ph: 414-874-4541
			Email: Kelli.holton@wfhc.org
	Rhinelander
	Ministry Medical Group at Saint Mary's Hospital
		Adedayo Onitilo	Ph: 715-393-1400
	Rice Lake
	Marshfield Clinic - Indianhead Center
		Adedayo Onitilo	Ph: 715-393-1400
	Sheboygan
	Saint Nicholas Hospital
		Anthony J. Jaslowski	Ph: 800-432-6049
	Stevens Point
	Marshfield Clinic at Saint Michael's Hospital
		Adedayo Onitilo	Ph: 715-393-1400
	Sturgeon Bay
	Green Bay Oncology, Limited - Sturgeon Bay
		Anthony J. Jaslowski	Ph: 800-432-6049
	Waukesha
	Waukesha Memorial Hospital Regional Cancer Center
		Michael A Thompson	Ph: 262-928-7632
	Weston
	Marshfield Clinic - Weston Center
		Adedayo Onitilo	Ph: 715-393-1400
	Wisconsin Rapids
	Marshfield Clinic - Wisconsin Rapids Center
		Adedayo Onitilo	Ph: 715-393-1400
	Riverview UW Cancer Center at Riverview Hospital
		Ron James Kirschling	Ph: 877-405-6866