|Phase IV||Treatment||Active||18 and over||Other||10-008104|
The investigators seek to compare two techniques of removing pre-cancerous lesions from the colon. The investigators also will compare two solutions used during the procedure to determine if either solution allows for an improved removal of the tumors.
Further Study Information
The primary aim of the study is to compare the efficacy, efficiency and safety of two types of snares used in Endoscopic Mucosal Resection (EMR), a combined needle and snare unit (ISnare, US Endoscopy) versus an oval braided snare with spiral wire (Snaremaster, Olympus). The secondary aim is to explore whether EMR efficacy and efficiency is depended upon the injection solution used, saline versus Gonak (a solution containing HPMC, saline, and epinephrine) for EMR.
- Sessile colorectal polyp
- laterally spreading lesions as defined by Paris Classification type II and > 1 cm or greater
- Those with ulcerated depressed lesions (Paris type III) or biopsy proven invasive carcinoma
- Inflammatory bowel disease patients
- Coagulopathy ( INR> 1.5) that cannot be corrected
Trial Lead Organizations/Sponsors
Mayo Clinic Cancer CenterUS Endoscopy
|Timothy A. Woodward||Principal Investigator|
|Joy Hardee||Ph: 904-953-8456|
|Mayo Clinic - Jacksonville|
Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01471756
Information obtained from ClinicalTrials.gov on January 21, 2013
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