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Clinical Trials (PDQ®)

Improving Complete Endoscopic Mucosal Resection (EMR) of Colorectal Neoplasia

Basic Trial Information
Trial Description
     Summary
     Further Trial Information
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IVTreatmentClosed18 and overOther10-008104
NCT01471756

Trial Description

Summary

The investigators seek to compare two techniques of removing pre-cancerous lesions from the colon. The investigators also will compare two solutions used during the procedure to determine if either solution allows for an improved removal of the tumors.

Further Study Information

The primary aim of the study is to compare the efficacy, efficiency and safety of two types of snares used in Endoscopic Mucosal Resection (EMR), a combined needle and snare unit (ISnare, US Endoscopy) versus an oval braided snare with spiral wire (Snaremaster, Olympus). The secondary aim is to explore whether EMR efficacy and efficiency is depended upon the injection solution used, saline versus Gonak (a solution containing HPMC, saline, and epinephrine) for EMR.

Eligibility Criteria

Inclusion Criteria:

  • Sessile colorectal polyp
  • laterally spreading lesions as defined by Paris Classification type II and > 1 cm or greater

Exclusion Criteria:

  • Those with ulcerated depressed lesions (Paris type III) or biopsy proven invasive carcinoma
  • Inflammatory bowel disease patients
  • Coagulopathy ( INR> 1.5) that cannot be corrected

Trial Contact Information

Trial Lead Organizations/Sponsors

Mayo Clinic Cancer Center

US Endoscopy

Timothy A. WoodwardPrincipal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01471756
ClinicalTrials.gov processed this data on October 17, 2013

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.

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