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NCI Dictionary of Cancer Terms


prostaglandin-endoperoxide synthase 2  listen  (PROS-tuh-GLAN-din-EN-doh-peh-ROK-side SIN-thays 2)

  An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to grow. Some tumors have high levels of prostaglandin-endoperoxide synthase 2 and blocking its activity may reduce tumor growth. Also called COX-2 and cyclooxygenase-2.