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NCI Drug Dictionary


silicon phthalocyanine 4 
A synthetic photosensitizer agent containing a large macrocyclic ring chelated with silicon. Silicon phthalocyanine 4 localizes primarily in mitochondrial cytosolic membranes and, after photoexcitation, forms reactive oxygen species that induce apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:Pc-4 (Silicone phthalocyanine)
Abbreviation:Pc 4