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NCI Drug Dictionary

  

naproxen 
A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Naprosyn
Code name:RS-3540
Chemical structures:6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid
d-2-(6-Methoxy-2-naphthyl)propionic Acid