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A synthetic long-acting octapeptide analogue of endogenous somatostatin. Octreotide pamoate binds to somatostatin receptors expressed by some neuroendocrine and non-neuroendocrine tumor cells, thereby initiating somatostatin receptor-mediated apoptosis. Other possible antineoplastic activities of this agent include suppression of tumor angiogenesis and tumor growth-promoting insulin-like growth factor 1 (IGF-1). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||octreotide pamoate LAR(SMS 201-995) |
|US brand names:||OncoLAR |
Sandostatin pamoate LAR
|Code names:||SMS 201-995 pa |
SMS 201-995 pa LAR