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NCI Drug Dictionary

NCI Drug Dictionary

  

famotidine 
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand names:Pepcid
Pepcid AC