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NCI Drug Dictionary


allogeneic GM-CSF-transfected myeloma cell vaccine 
An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Upon vaccination, allogeneic GM-CSF-based myeloma cellular vaccine secretes GM-CSF, which may potentiate a tumor-specific cytotoxic T-lymphocyte (CTL) response against myeloma cancer cell-associated antigens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:allogeneic GM-CSF-based myeloma cell vaccine
allogeneic granulocyte macrophage colony-stimulating factor-transfected myeloma cell vaccine