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NCI Drug Dictionary

  

topical piperidine nitroxide MTS-01 
A topical gel containing a cell permeable hydrophilic piperidine nitroxide with potential radioprotective and antioxidant activity. As a stable, free radical compound, MTS-01 may be able to protect cells against the damaging effects of reactive oxygen species (ROS), upon exposure to ionizing radiation and oxidative stress. The topically applied MTS-01 may protect normal tissue from radiation-induced toxicity, such as radiation dermatitis, during radiation therapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Tempol
Code name:MTS-01
Chemical structure:4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl