Questions About Cancer? 1-800-4-CANCER

NCI Dictionary of Genetics Terms

NCI Dictionary of Genetics Terms


3 results found for: U



  • unaffected  (UN-uh-FEK-ted)
    An individual who does not manifest symptoms of a condition or disease occurring in his or her family.

  • unclassified variant  (un-KLA-sih-fide VAYR-ee-unt)
    A variation in a genetic sequence whose association with disease risk is unknown. Also called variant of uncertain significance, variant of unknown significance, and VUS.

  • uninformative  (UN-in-FOR-muh-tiv)
    A negative test result in an individual where a clearly deleterious mutation has not been found in any family members. The genetic risk status of such an individual must be interpreted in the context of his or her personal and family history. Also called inconclusive and indeterminate.