Researchers at the National Cancer Institute are trying to develop cancer vaccines by identifying changes that occur that make cancerous cells different from normal cells and educating the immune system to recognize and destroy the cancer cells as foreign bodies while sparing the normal cells. Dr. Samir Khleif discusses two new cancer vaccine clinical trials.
"We have one trial that is open now for ovarian cancer where we vaccinate patients against the p53 gene. And this is a trial where we treat patients with ovarian cancer that have no disease that's seen at this stage – they've already been treated – or their marker is going up, which is an indication that the cancer might come back. We have another trial where now we also vaccinate patients against the p53 gene for patients with breast cancer - that have advanced breast cancer."
For more information about these or any other cancer vaccine trials, call
1-800-4-CANCER. Information is also available on the National Cancer Institute web site at: http://www.nci.nih.gov/. This is Calvin Jackson, the National Institutes of Health, Bethesda, Maryland.