National Cancer Institute NCI Cancer Bulletin: A Trusted Source for Cancer Research News
August 10, 2010 • Volume 7 / Number 16


An echocardiogram showing a measurement of the heart's left ventricleProtein Helps Predict Cancer Therapy-induced Heart Damage

In a prospective study of 251 women with HER2-positive breast cancer, women with elevated blood levels of a protein called troponin I had significantly higher rates of cardiotoxicity (heart damage) during treatment with trastuzumab (Herceptin) than women who did not have elevated levels of troponin I before or during treatment. Women with elevated troponin I were also three times less likely to recover from the observed heart damage. The results came from a study led by Dr. Daniela Cardinale of the European Institute of Oncology in Milan, Italy, and were published online August 2 in the Journal of Clinical OncologyRead more > >


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  • Legislative Update

    • Project Cancer Education: An Introduction to Translational Research at NCI
  • Update

    • NCI Recovery Act Web Site Highlights Cancer Disparity Studies
  • Notes

    • NIH Intramural Research Program Is Recruiting Earl Stadtman Investigators
    • Office of China Cancer Programs Issues Report on Symposium
    • New Issue of OCG e-News Available

Selected articles from past issues of the NCI Cancer Bulletin are available in Spanish.

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