Three NIH-funded Researchers Win 2009 Nobel Prize
Drs. Elizabeth H. Blackburn of the University of California, San Francisco; Carol W. Greider of Johns Hopkins University School of Medicine; and Jack W. Szostak of Harvard Medical School have won the Nobel Prize in Physiology or Medicine for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. Telomeres limit the number of times a cell can divide and therefore play an important role in aging and cancer.
During a visit to the NIH campus last week, President Barack Obama announced that NIH will spend $275 million over the next 2 years to catalogue the genetic changes driving more than 20 types of cancer. Read more > >
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Clinical trial is being planned to test lapatinib in selected patients
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Accrual suspended while researchers study adverse events
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Higher dose improved rates of remission and overall survival compared with standard dose
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Studies find no overall increased risk of pregnancy complications or birth defects
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PLX4032 is moving into phase II and III trials for this difficult-to-treat disease
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Discovery could help doctors identify women at risk of invasive or metastatic disease
At NCI, we clearly recognize cancer as a global health crisis, and one for which the worldwide impact—both personal and economic—is rapidly expanding. A recent study reported that in the past 30 years the global burden of cancer, based on the incidence of new cancer cases and annual deaths, has doubled.
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The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.
For more information about cancer, call 1-800-4-CANCER or visit http://www.cancer.gov.
NCI Cancer Bulletin staff can be reached at ncicancerbulletin@mail.nih.gov.
