National Cancer Institute NCI Cancer Bulletin: A Trusted Source for Cancer Research News
November 27, 2012 • Volume 9 / Number 23


NCI's Steven Rosenberg Awarded Keio Medical Science Prize

Dr. Steven Rosenberg
Dr. Steven Rosenberg

Dr. Steven Rosenberg, chief of surgery at NCI’s Center for Cancer Research, has won a 2012 Keio Medical Science Prize for his development of immunotherapies for patients with cancer. Japan’s Keio University awards the prize each year to recognize research achievements in the fields of medicine and life science.

Dr. Rosenberg was the first to show that stimulating the immune system with interleukin-2, a protein that helps regulate immune responses, could cause durable tumor shrinkage in patients with metastatic melanoma and kidney cancer. Dr. Rosenberg and his colleagues have identified and characterized dozens of tumor antigens—molecules on cells that can generate immune responses—that have been widely used in the development and study of cancer vaccines.

Dr. Rosenberg also led efforts to improve the effectiveness of immunotherapies by pioneering a technique called adoptive cell transfer, which has led to durable, complete cancer remissions in a number of patients with metastatic cancer. His recent work using genetically engineered T cells was the first to successfully treat patients with advanced metastatic melanomas, sarcomas, and lymphomas that did not respond to standard therapies.

Further reading: “A Transfer of Power: Harnessing Patients’ Immune Cells to Treat Their Cancer;” “Complex Immune-Based Cancer Treatment Shows Signs of Progress;” and “Genetically Engineered Immunotherapy for Advanced Cancer

NCI Advisory Committee on Clinical Trials Will Meet Friday

The Clinical Trials and Translational Research Advisory Committee (CTAC) will meet later this week on November 30 on the NIH main campus in Bethesda, MD.

The meeting will highlight the NCI Cancer Clinical Investigator Team Leadership Award program, the Pancreatic Cancer Working Group, an update on efforts to transform the NCI clinical trials enterprise, and changes to NCI’s community oncology trials programs.

The agenda is available online, and the meeting is open to the public. Those who cannot attend in person can watch the videocast

AccrualNet Website Gets New Look

Accrual Net website

NCI recently redesigned the AccrualNet website, a centralized resource for clinical trial professionals that features information on trial recruitment, strategies, and tools. The new design makes it easier to access the site’s resources, including training tools for new staff, sample letter templates, and best practices for communicating with patients.

AccrualNet seeks to help clinical trial professionals connect with others across the country and around the world. Registered users can now create their own “Community of Practice,” where invited members can interact and learn from each other about common issues related to clinical trial accrual. To learn more about Communities of Practice and how to use AccrualNet, watch the video tutorial.

New features include

  • A growing repository of more than 700 resources aligned with each phase of the clinical trial accrual lifecycle;
  • An updated space to connect with clinical trial colleagues and ask questions, share experiences, solve challenges, and celebrate success;
  • Updated professional education resources to help train new team members; and
  • Patient education materials.