NEWS
New Surgeon General’s Report Outlines How Tobacco Smoke Causes Disease
The U.S. Surgeon General, Dr. Regina M. Benjamin, released a report last week describing in detail how tobacco smoke causes disease and death. A compendium of basic research, the 700-page report demonstrates that any exposure to tobacco smoke, either direct or secondhand, causes immediate damage to cells in the body and can lead to disease and death. Read more > >
Study Estimates More than 600,000 Deaths Worldwide Caused by Secondhand Smoke
Majority of burden borne by women and childrenZoledronic Acid Does Not Improve Disease-Free Survival in Breast Cancer
Still unclear whether estrogen mediates the anticancer effects of bisphosphonatesRegular Sunscreen Use May Reduce Invasive Melanoma Risk
Study is first randomized investigation of sunscreen use and melanomaHormone Therapy for Low-Risk Prostate Cancer Declines When Medicare Reimbursements Are Reduced
Decrease likely indicates the treatment was overprescribedStudy Shows Strong Link between Obesity and Mortality
Data also identify BMI range at which mortality risk is lowestNew Subtype of Acute Myeloid Leukemia Identified
Study uncovers a link between metabolic genes and a cell’s epigenetic programScreening Compliance, Stage of Cancers Detected Vary by Demographic
Report suggests greatest gains could be made in colorectal cancer screening
COMMENTARY
A Conversation with Dr. James H. Doroshow about NCI’s Clinical Trials Cooperative Group Program
The director of NCI’s Division of Cancer Treatment and Diagnosis addresses the Institute of Medicine’s recommendations to improve NCI’s Clinical Trials Cooperative Group Program by consolidating the existing adult groups into a smaller number of groups that would function in a more closely integrated manner. Read more > >
A MESSAGE TO READERS
NCI Cancer Bulletin Publication Break
The next issue of the NCI Cancer Bulletin will be published on January 11, when we resume our usual biweekly schedule. If you are not yet a subscriber, please submit your e-mail address in the toolbox above to begin your free subscription.
IN DEPTH
Trial Suggests New Treatment Option for Hodgkin Lymphoma
Manufacturer will seek FDA approval based on phase II clinical trial resultsFeatured Clinical Trial: Targeting Tumor Metabolism in Papillary Kidney Cancers
Will combined therapy improve responses in patients with advanced disease?Statistical Strength in Numbers: International Clinical Trials for Rare Cancers
NCI and the American Society of Clinical Oncology hold a joint meeting on collaborating across borders on these trials
UPDATES
FDA Update
- FDA Advisory Committee Votes against Two Drugs for Prostate Cancer Prevention
Cancer.gov Update
- NCI Recovery Act Web Site Highlights Research on Genomic Mutations in Childhood Cancers

- NCI Recovery Act Web Site Highlights Research on Genomic Mutations in Childhood Cancers
Notes
- Final NCAB Meeting of 2010 Held Last Week
- NCI Director Announces New Senior Staff Member
Selected articles from past issues of the NCI Cancer Bulletin are available in Spanish.
The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.
For more information about cancer, call 1-800-4-CANCER or visit http://www.cancer.gov.
NCI Cancer Bulletin staff can be reached at ncicancerbulletin@mail.nih.gov.

