Building a Molecular Foundation for Cancer Prevention
In this issue of the NCI Cancer Bulletin, we offer a closer look at cancer prevention research. It's an enormous topic, but I think you'll see as you read that, beyond what we already know about behavior change and cancer prevention, the field is transitioning toward studies that delve into the molecular foundations of health and disease.
Some of the most promising science under way takes advantage of advances in fields such as genomics, transcriptomics, proteomics, and metabolomics - what some call "molecular prevention." Read more
Mouse Models Offer Promise in the Science of Cancer Prevention
The new generation of genetically-engineered mouse models (GEMs) holds promise for helping cancer prevention researchers refine and speed up testing of potential preventive agents. These mice are programmed to develop specific types of cancer in ways that mimic human cancer. That may make it easier for scientists, using sophisticated imaging technologies, to gauge the effects of cancer preventive substances.
This summer, NCI will convene a "think tank" of 15-18 invited experts from the fields of early intervention, prevention, and prevention screening, as well as from the NCI Mouse Models of Human Cancers Consortium (MMHCC), to develop research plans that fully explore the promise of GEMs. Read more