Salk Institute for Biological Studies Cancer Center
Director: Dr. Walter Eckhart • 10010 North Torrey Pines Road, La Jolla, CA 92037 • Phone: 858-453-4100 ext. 1386 • Web site: http://www.salk.edu
Today, Cancer Center investigations comprise approximately half of the research conducted by the Salk Institute and occupy more than 60,000 square feet of laboratory space within the original campus. This research supports 22 faculty members, 150 postdoctoral researchers, 45 graduate students, and 80 research assistants.
The Salk Institute Cancer Center currently focuses on three research areas: molecular biology and genetics, growth control, and cell and developmental biology. Within these areas, scientists are studying signal transduction pathways using phosphorylation and ubiquitination that regulate cell size and cell proliferation in normal cells, cancer cells, and animal models; the functions of tumor suppressor proteins, including p53, LKB1, and APC; the response of cells to DNA damage and how this is perturbed in cancer cells; the involvement of telomere dysfunction in cancer; the connections between aging and cancer; and the role of stem cells in cancer.
Other Notable Programs
Research underway in the Cancer Center is supported by competitively awarded grants of approximately $16 million. In addition, Cancer Center members have been working with The Genomics Institute of the Novartis Research Foundation to carry out genome-wide screens, and the Salk Institute is part of the San Diego Consortium for Regenerative Medicine, which has plans to establish a facility that will serve the La Jolla mesa area, funded in part by the California Institute for Regenerative Medicine (CIRM). Most recently, the Salk Institute received a $2.3 million facilities grant from CIRM to fund the development of shared laboratory space where investigators will conduct scientific research on human embryonic stem cells.