HIV Drugs Show Promise Fighting Cancer in Preclinical Studies
Results published in the September 1 Clinical Cancer Research showed that three of six drugs used to treat HIV/AIDS also inhibit an important target in cancer, Akt, stopping the growth of cancer cells, not only in vitro, but also when those cells are transplanted into mice. Read more
Creating a Bridge to Success
Improving the translation of promising laboratory findings into the clinic is a top NCI priority. One of the most important mechanisms by which NCI helps bring new interventions to patients and clinicians is the Small Business Innovation Research (SBIR) program, which was created by Congress to strengthen the role of small, innovative companies in federally supported research and development.
Traditionally, venture capital firms, larger pharmaceutical and biotechnology companies, and other private investors have provided the investments that these small businesses needed to advance a product through the stages of commercial development. Over the past decade, however, small businesses have struggled to secure such funding. It has been reported that last year only 5 to 6 percent of biomedical deals into which U.S. venture capital firms entered were with companies in the formative stages. Read more