NCI Cancer Bulletin: A Trusted Source for Cancer Research NewsNCI Cancer Bulletin: A Trusted Source for Cancer Research News
January 22, 2008 • Volume 5 / Number 2 E-Mail This Document  |  Download PDF  |  Bulletin Archive/Search  |  Subscribe

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Featured Article

Research Community Mourns Death, Celebrates Life of Judah Folkman

Dr. Judah Folkman One of the most highly praised and respected cancer researchers, Dr. Judah Folkman of Harvard University and Children's Hospital Boston, died last week from a heart attack. He was 74.

In the wake of his unexpected death, leading researchers praised his groundbreaking work on the role of angiogenesis in tumor development, calling him a pioneer who almost single-handedly altered how cancer is viewed and treated.

"Dr. Folkman championed and led the field of angiogenesis," said NCI Director Dr. John E. Niederhuber. "His dedicated leadership has created the ultimate legacy: a legion of students and fellows, many of whom are now important scientists and scientific leaders in their own right."   Read more  

Clinical Research Highlights

Two Studies Identify Drivers of Metastases

A study published in the January 10 Nature has pinpointed several microRNAs (miRNAs) - tiny RNA strands that regulate gene expression - that help suppress breast cancer metastases.

Researchers from Memorial Sloan-Kettering Cancer Center examined miRNAs in breast cancer cell lines that were highly metastatic to bone and lung compared with control breast cancer cell lines. They chose to focus further studies on the six miRNAs whose expression was most decreased in the metastatic cells.   Read more  



The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI). NCI, which was established in 1937, leads the national effort to eliminate the suffering and death due to cancer. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.

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