National Cancer Institute NCI Cancer Bulletin: A Trusted Source for Cancer Research News
January 13, 2009 • Volume 6 / Number 1

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BREAKING NEWS

ASCO Urges KRAS Gene Testing for Colorectal Cancer

The American Society of Clinical Oncology (ASCO) recommended today that patients with metastatic colorectal cancer who are candidates for anti-EFGR therapy have their tumors tested for KRAS gene mutations. In a “provisional clinical opinion,” ASCO recommends that patients with mutated forms of the KRAS gene should not receive the drugs cetuximab (Erbitux) and panitumumab (Vectibix), based on recent studies indicating that these drugs are only effective in patients with normal forms of the gene.

NEWS

A studio photo of chemotherapy drugs in a dripping IV bottle

5-FU-Based Chemotherapy Cures Some Patients with Colon Cancer

Researchers from the Adjuvant Colon Cancer Endpoints (ACCENT) Group used individual patient data from 18 phase III trials of adjuvant fluorouracil-based chemotherapy for colon cancer to show that the regimens provide their survival benefit primarily by reducing the high risk of recurrence within the first 2 years after surgery.  Read more > >

COMMENTARY

Director's Update: Resource Digs Deep into NCI's Research Funding

NCI recently launched a newly enhanced Funded Research portal on its Web site. For a decade or more visitors to www.cancer.gov could search the cancer research portfolio, but the enhanced portal now provides consolidated information from varying NCI locations on one site, including funding and other data on NCI's intramural research program. The result is a significant increase in public access to this broader range of data. Read more > >

IN DEPTH

UPDATES

  • FDA Update

    • New Prostate Cancer Drug Approved
    • Gardasil Indication for Men Reviewed
    • A Warning for Bone Density Drug
  • CMS Update

    • CMS Proposes Expanding Medicare Coverage of PET Scans in Cancer Patients
  • Notes

    • NCI Scientists Receive 2008 HHS Awards
    • NCI Holds Annual Intramural Scientific
      Retreat
    • New Issue of CCR Connections Released

The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.

For more information about cancer, call 1-800-4-CANCER or visit http://www.cancer.gov.

NCI Cancer Bulletin staff can be reached at ncicancerbulletin@mail.nih.gov.

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