National Cancer Institute NCI Cancer Bulletin: A Trusted Source for Cancer Research News
March 10, 2009 • Volume 6 / Number 5

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Funding Ban Lifted on Human Stem Cell Research

Yesterday, President Barack Obama signed a Presidential Executive Order removing federal funding barriers to scientific research involving human embryonic stem cells. For background on stem cells and their potential impact on scientific research, please visit NIH’s stem cell information page.


Ex vivo reconstructed skin model of melanoma. This skin sample contains melanoma cells without SOX9, which have formed invasive tumors. (Image courtesy of Drs. Thierry Passeron and Vincent Hearing.)

Potential New Target for Melanoma Treatment Identified

Melanoma skin cancers are notoriously resistant to chemotherapy and radiation therapy, and most patients have few treatment options once the cancer has spread to other parts of the body. Researchers have now identified a protein called SOX9 that both inhibits the proliferation of melanoma cells and makes them sensitive to the chemotherapy drug retinoic acid. These findings, published March 9 in the Journal of Clinical Investigation, suggest that SOX9 may be a promising new target for melanoma therapies. Read more > >


Dr. Robert Croyle

Guest Director's Update: Collaborative Initiative Will Tackle Obesity among Youth

By Dr. Robert Croyle

Convincing evidence has been found associating excess body fat and colorectal, pancreatic, esophageal, endometrial, postmenopausal breast, kidney, and thyroid cancers, as well as associating excess abdominal fat and colorectal cancer.

This is why NCI has signed on to be part of an ambitious new initiative that we believe can help improve the health of families in communities across the country. Dubbed the National Collaborative on Childhood Obesity Research (NCCOR), other partners in the initiative include four NIH institutes, divisions and offices in the CDC, and the Robert Wood Johnson Foundation. Read more > >


More Information about the Recovery Act and Challenge Grants

NCI has created a Web site—
recovery—in recognition of the cancer community’s interest in the American Recovery and Reinvestment Act of 2009. The site includes an overview of the legislation and will be updated regularly with NCI’s implementation plans and related announcements, including links to detailed information about the NIH Challenge Grants in Health and Science Research and recently posted funding opportunities. Updated information on NCI’s Recovery Act efforts will also be made available on HHS’ Recovery Web site. Your suggestions about NCI’s participation in meeting the Recovery Act goals are important, and we welcome your comments and suggestions.



  • Notes

    • New NCI Fellowship Honors Dr. Alan Rabson
    • NCI Lecture Series Features Dr. Michael Jung
    • Call for U.S.-Japan Workshop Proposals
    • BSA Meeting Held
    • First Lady of Senegal Visits NCI
    • New Orleans Community Clinical Programs Honored

The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.

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