National Cancer Institute NCI Cancer Bulletin: A Trusted Source for Cancer Research News
April 7, 2009 • Volume 6 / Number 7

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Clinical Trials Promotional Tools Available from NCI

Ask Me button design

NCI recently made available two patient education posters and a pin to increase awareness about clinical trials by sparking discussions with cancer patients who may be interested in enrolling in a trial. The posters and pins introduce patients to the concept of clinical trials, complement education and recruitment efforts, and serve as conversation starters to discuss trials in a general context before exploring specific trials with patients. The pins can also be worn by patients participating in clinical trials or their family members and friends—individuals who can help increase awareness.

For more information about the posters and pins, call NCI's Cancer Information Service toll free at 1-800-4-CANCER or order them online by clicking:

NCI-Frederick Prepares for Annual Spring Research Festival

NCI-Frederick 13th Annual Spring Research Festival logo

The National Cancer Institute at Frederick, in partnership with the National Interagency Confederation for Biological Research at Fort Detrick, will hold the 13th Annual Spring Research Festival on April 29 and 30 in Frederick, MD. Scientific staff, including students, technical support staff, postdoctoral fellows, and principal investigators, will present posters describing their research to the joint scientific communities. This year's festival will also include a health and safety exposition, educational information, safety and scientific displays, and commercial exhibits on the latest scientific equipment and technologies. More information is available online.

CTCAE 4.0 Posted for Public Review

NCI's Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 is widely accepted throughout the oncology research community as the standard grading scale for defining protocol parameters such as maximum tolerated dose, dose modification, and comparison of safety profiles between interventions.

NCI's Cancer Therapy Evaluation Program and Center for Bioinformatics have revised CTCAE version 3.0 to address agreement with the Medical Dictionary for Regulatory Activities (MedDRA) terminology, integration with caBIG data systems, and long-term governance of CTCAE. A draft of CTCAE version 4.0 is available for public review at under “CTEP Highlights" through April 10. The site includes further information about the revision and instructions for submitting comments. Questions should be addressed to

Meet NCI Experts at AACR

Logo for the American Association for Cancer Research 100th Annual Meeting 2009    NCI exhibit booth

Join Dr. John E. Niederhuber on Monday, April 20, at 11:45 a.m. for the NCI Director Session during the American Association for Cancer Research Annual Meeting. Learn about NCI's programs and Web sites by visiting booth #306 in the exhibit hall. NCI experts will be available to talk about a wide range of topics. See the schedule below.

Sunday, April 19
1:00 p.m.NCI Intramural Fellowships 
 Jonathan Wiest, Center for Cancer Training
2:00 p.m.NCI-Funded Research Portfolio 
 Lisa Krueger, Division of Extramural Activities  
3:00 p.m.The Cancer Biomedical Informatics Grid: Resources to Support Translations Research 
 Donna Messersmith, Center for Biomedical Informatics and Information Technology
4:00 p.m.Collaborating with NCI in Pediatric Oncology Drug Development—From Target Discovery to Early Phase Clinical Trials
 Malcolm Smith, Cancer Therapy Evaluation Program
Monday, April 20
9:00 a.m.NCI Career Development Awards
 Lester Gorelic, Center for Cancer Training
10:00 a.m.Cancer Nanotechnology—Opportunities and Challenges
 Piotr Grodzinski, Center for Strategic Scientific Initiatives
11:00 a.m.Epigenetics and Cancer Epidemiology
 Mukesh Verma, Division of Cancer Control and Population Sciences
12:00 p.m.NCI-Funded Research Portfolio
 Michelle Vos, Division of Extramural Activities
1:00 p.m.NCI Cancer Complementary and Alternative Medicine Program
 Libin Jia, Office of Cancer Complementary and Alternative Medicine
2:00 p.m.Prostate Cancer Epidemiology—What's New?
 Ann Hsing, Division of Cancer Epidemiology and Genetics
3:00 p.m.NCI-Funded Research Portfolio
 Lisa Krueger, Division of Extramural Activities
Tuesday, April 21
9:00 a.m.NIH K99/R00 Pathway to Independence Award 
 Nancy Lohrey, Center for Cancer Training
10:00 a.m.NCI-Funded Research Portfolio 
 Lisa Krueger, Division of Extramural Activities
11:00 a.m.Advancing Protein Science for Personalized Cancer Care
 Henry Rodriquez, Clinical Proteomic Technologies for Cancer, Center for Strategic Scientific Initiatives 
12:00 p.m.Streamlining Clinical Trials Contract Negotiations
 Sheila Prindiville, Coordinating Center for Clinical Trials 
1:00 p.m.How to Tap into NCI SBIR Dollars to Support Innovative Cancer Research
 Michael Weingarten, Small Business Innovation Research Program
2:00 p.m.Quality Biospecimens are the Key to Personalized Medicine 
 Carolyn Compton, Office of Biorepositories and Biospecimen Research, Center for Strategic Scientific Initiatives
3:00 p.m.NCI-Funded Research Portfolio 
 Lisa Krueger, Division of Extramural Activities
Wednesday, April 22
9:00 a.m.Cancer Genetics Network
 Scott Rogers, Division of Cancer Control and Population Sciences
11:00 a.m.Clinical Grants & Contracts
 William Merritt, Cancer Therapy Evaluation Program

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