National Cancer Institute NCI Cancer Bulletin: A Trusted Source for Cancer Research News
July 14, 2009 • Volume 6 / Number 14

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State-of-the-Science Conference on Ductal Carcinoma In Situ Slated for September

Logo for NIH State-of-the-Science Meeting on Ductal Carcinoma In Situ

On September 22–24, NCI and the NIH Office of Medical Applications of Research will convene a state-of-the-science conference on ductal carcinoma in situ (DCIS) at the Natcher Conference Center on the NIH campus. The conference will address the following key questions:     

  • What are the incidence and prevalence of DCIS and its specific pathologic subtypes, and how are incidence and prevalence influenced by mode of detection, population characteristics, and other risk factors?
  • How does the use of MRI or sentinel lymph node biopsy impact important outcomes in patients diagnosed with DCIS?
  • How do local control and systemic outcomes vary in DCIS based on tumor and patient characteristics?
  • In patients with DCIS, what is the impact of surgery, radiation, and systemic treatment on outcomes?
  • What are the most critical research questions for the diagnosis and management of DCIS?

Invited experts will present information pertinent to these questions, and a systematic literature review will be summarized. Conference attendees will have the opportunity to ask questions and provide statements during open discussion periods. After weighing the scientific evidence, an unbiased, independent panel will prepare and present a consensus statement addressing the key conference questions.

The conference is free and open to the public but advance registration is recommended. Go online to find more information and register.

Chemical Biology Consortium Kick-off Meeting Set for August

Logo for NCI's Chemical Biology Consortium meeting

NCI invites the drug discovery and development communities to the inaugural meeting of the Chemical Biology Consortium (CBC), which will be held August 10 at the Natcher Conference Center on the NIH campus.

The CBC is part of a new, rapidly evolving NCI Experimental Therapeutics (NExT) program, which is opening the oncology drug discovery and development pipeline to researchers in academia, industry, and the government. The CBC will be one entry point into the pipeline and it will interface with other NCI programs that aim to expedite new drugs from the laboratory to the bedside.

The day-long meeting will showcase the 11 newly established CBC centers, chosen by NCI for their world-class screening and chemistry qualifications.

More meeting information and registration are available online.

Manifesto on Childhood Cancer Emerges from Meeting in Senegal

Dakar Manifesto

Representatives from 21 countries met in Dakar, Senegal, on July 1 and 2 to review progress and strengthen measures in the fight against cancer in low- and middle-income countries through the My Child Matters program, created in 2004 by the International Union Against Cancer (UICC).

At the Dakar meeting, experiences were shared by representatives from Bangladesh, Burkina Faso, Cameroon, Côte d’Ivoire, Egypt, France, Honduras, Italy, Kenya, Mali, Morocco, the Netherlands, Paraguay, the Philippines, The Republic of Congo, Senegal, Switzerland, Tanzania, Turkey, Ukraine, and the United States. Dr. Joe Harford, director of NCI's Office of International Affairs and member of the My Child Matters steering committee, represented NCI at the meeting and gave the opening lecture, “The Burden of Cancer in Africa.”

Meeting participants signed the Dakar Manifesto, which calls on all stakeholders and institutions concerned for more participation and action to improve the outcome of childhood cancers around the world.

My Child Matters is one of the largest initiatives dedicated to fighting childhood cancer in low- and middle-income countries. With support from sanofi-aventis, it has supported 33 field projects led by hospitals and nongovernmental organizations in 21 countries on 4 continents to improve cancer care, including providing better information, education, and prevention; improving professional training and ensuring earlier diagnosis; fostering better access to health care, pain management, and palliative care; and increasing understanding of the social aspects of this disease, both for children and their families. By the end of 2008, more than 12,800 children and 6,600 families had been helped by this program, and some 2,850 health care professionals had received training.

New Issue of CCR Connections Released

cover of CCR Connections

NCI’s Center for Cancer Research (CCR) recently released a new issue of its news magazine, CCR Connections. The Web version of volume 3, issue 1 is available online.

In the latest issue, readers will find features on metastatic cancer and Wnt signaling in cancer development and progression, a commentary by former CCR fellow Dr. Aurora Medina-Sanson, and information on recent journal articles and staff awards.

CCR Connections is published semiannually. Send a request for a print or online subscription to

New State Cancer Legislative Database Newsletter and Fact Sheet Now Available

cover of State Cancer Legislative Database

NCI’s State Cancer Legislative Database (SCLD) Web site has been updated. A fact sheet on cancer screening and the spring 2009 issue of the SCLD Update have been added to the site. This latest issue of the SCLD Update includes a summary of enacted legislation and adopted resolutions between January and March 2009, as well as a legislative data “byte” highlighting the number of states with measures related to private health insurance coverage for breast cancer treatment services.

The SCLD program contains information synthesized from state-level laws. SCLD does not contain state-level regulations; measures implemented by counties, cities, or other localities; case law; Attorneys General opinions; or data addressing the implementation of state laws—all of which may vary significantly from the laws reported by the SCLD. For more information, go to

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