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1. Panel Calls for Reducing Colorectal Cancer Deaths by Striking Down Barriers to Screening
(Posted: 02/04/2010) - Rates of screening for colorectal cancer are consistently lower than those for other types of cancer, particularly breast and cervical. Although the screening rates in the target population--adults over age 50--have increased from 20-30 percent in 1997 to nearly 55 percetn in 2008--the rates are still too low. An NIH state-of-the-science panel was convened this week to identify ways to further increase the use and quality of colorectal cancer screening in the United States.
2. Antibodies Against Abnormal Glycoproteins Identified as Possible Biomarkers for Cancer Detection
(Posted: 02/02/2010) - Scientists have found that cancer patients produce antibodies that target abnormal glycoproteins (proteins with sugar molecules attached) made by their tumors. The result of this work suggests that antitumor antibodies in the blood may provide a fruitful source of sensitive biomarkers for cancer detection.
3. The Cancer Genome Atlas Identifies Distinct Subtypes of Deadly Brain Cancer That May Lead to New Treatment Strategies
(Posted: 01/19/2010) - The most common form of malignant brain cancer in adults, glioblastoma multiforme, is not a single disease but appears to be four distinct molecular subtypes, according to a study by the Cancer Genome Atlas (TCGA) Research Network. The researchers of this study also found that response to aggressive chemotherapy and radiation differed by subtype.
4. News Note: Evidence for Asymmetric Cell Division in Cancer Cells Identified
(Posted: 01/19/2010) - Scientists at NCI have identified a novel form of cell division in lung cancer cells and reported those findings in PNAS online the week of Jan. 18, 2010.
5. Diet May Protect Against Gene Changes in Smokers
(Posted: 01/12/2010) - Leafy green vegetables, folate, and some multivitamins could serve as protective factors against lung cancer in current and former smokers, according to a study that is a first step in understanding a complex association.
6. Gene Mutations Reveal Potential New Targets for Treating a Type of Non-Hodgkin's Lymphoma
(Posted: 01/06/2010) - Researchers have discovered genetic mutations that may contribute to the development of an aggressive form of non-Hodgkin's lymphoma. These findings provide insight into a mechanism that cancer cells may use to survive, thus identifying potential new targets for treatment of the disease.
7. Drug for Multiple Myeloma Demonstrated to Significantly Extend Disease-Free Survival
(Posted: 12/18/2009) - Initial results from a large, randomized clinical trial for patients with multiple myeloma, a cancer of the blood and bone marrow, showed that patients who received the oral drug lenalidomide (Revlimid, also known as CC-5013) following a blood stem cell transplant had their cancer kept in check longer than patients who received a placebo.
8. Annual Report to the Nation Finds Continued Declines in Overall Cancer Rates; Special Feature Highlights Current and Projected Trends in Colorectal Cancer
(Posted: 12/07/2009) - Rates of new diagnoses and rates of death from all cancers combined declined significantly in the most recent time period for men and women overall and for most racial and ethnic populations in the United States, according to a report from leading health and cancer organizations.
 
9. Gene's Position in the Nucleus Can be Used to Distinguish Cancerous from Normal Breast Tissue
(Posted: 12/06/2009) - Researchers have identified several genes whose spatial position inside the cell nucleus is altered in invasive breast cancer when compared to normal breast tissue. The findings suggest that cancer cells may have disease-specific, three-dimensional gene arrangements and raise the possibility that such gene positioning patterns could be used as a new diagnostic strategy to distinguish cancer tissue from normal tissue.
10. News Note: NCI Awards Cancer Information Service Contact Center
(Posted: 12/03/2009) - The National Cancer Institute announced yesterday the selection of a single organization for a multiple year contract award to operate its Cancer Information Service (CIS) Contact Center. The program will be located at Fred Hutchinson Cancer Research Center in Seattle, Wash., and will serve the United States, Puerto Rico, the U.S. Virgin Islands, and the U.S.-associated Pacific Territories.
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