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Roswell Park study suggests additional applications for FL118 as personalized therapy for cancer
NCI Cancer Center News
(Posted: 12/16/2014) - Study results showed that FL118 can also activate the p53 tumor-suppressor pathway in cancer cells, encouraging cell senescence, or aging.

Ohio State researchers find that long noncoding RNAs are a novel prognostic marker in older patients with acute leukemia
NCI Cancer Center News
(Posted: 12/16/2014) - A new study shows that patterns of molecules called long noncoding RNAs might help doctors choose the least toxic, most effective treatment for many older patients with acute myeloid leukemia.

More than 300 million people in at least 70 countries use smokeless tobacco
NCI/CDC Press Release
(Posted: 12/15/2014) - The first-ever report on the global use and public health impact of smokeless tobacco finds that more than 300 million people in at least 70 countries use these harmful products. The report is titled Smokeless Tobacco and Public Health: A Global Perspective.

UT Southwestern researchers note that signaling mechanism could be target for survival, growth of tumor cells in brain cancer
NCI Cancer Center News
(Posted: 12/15/2014) - UT Southwestern Medical Center neurology researchers have identified an important cell signaling mechanism that plays an important role in brain cancer and may provide a new therapeutic target.

U Penn Medical School researchers find that most women with early-stage breast cancer in US receive radiation for too long
NCI Cancer Center News
(Posted: 12/11/2014) - Two-thirds of women treated for early-stage breast cancer in the US receive longer radiation therapy than necessary, according to a new study published in JAMA this week from Penn Medicine.

Premenopausal women who received ovarian suppression treatment along with tamoxifen had a lower risk of breast cancer recurrence
NCI News Note
(Posted: 12/11/2014) - A clinical trial sponsored and supported by NCI showed that suppressing ovarian function reduced breast cancer recurrence in premenopausal women receiving the drug tamoxifen after surgery for early-stage breast cancer.

Ohio State U study finds that experience counts with radiation therapy for head and neck cancer
NCI Cancer Center News
(Posted: 12/09/2014) - Radiation therapy for head and neck cancer is highly complex, and a new study published in the Journal of Clinical Oncology with an accompanying editorial suggests that medical centers with more experience centers have better patient outcomes.

Dana-Farber researchers find that a new agent causes small cell lung tumors to shrink in pre-clinical testing
NCI Cancer Center News
(Posted: 12/09/2014) - Small cell lung cancer has shown itself vulnerable to an agent that disables part of tumor cells’ basic survival machinery, researchers at Dana-Farber Cancer Institute and the Massachusetts Institute of Technology reported.

Dana-Farber researchers find that a new agent causes small cell lung tumors to shrink in pre-clinical testing
NCI Cancer Center News
(Posted: 12/09/2014) - Small cell lung cancer has shown itself vulnerable to an agent that disables part of tumor cells’ basic survival machinery, researchers at Dana-Farber Cancer Institute and the Massachusetts Institute of Technology reported.

Dana-Farber researchers find that a narrow subset of cells is responsible for metastasis in multiple myeloma
NCI Cancer Center News
(Posted: 12/08/2014) - Dana-Farber researchers report that multiple myeloma is driven to spread by a subset of the myeloma cells within a patient’s body, and that attacking those specific subsets with targeted drugs may be better targets for therapy.

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