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U of Michigan researchers develop new potential drug for rare leukemia
NCI Cancer Center News
(Posted: 03/31/2015) - Researchers at the University of Michigan Comprehensive Cancer Center have developed a new drug candidate that shows potential in laboratory studies against a rare type of acute leukemia.

New analysis of breast cancer subtypes could lead to better risk stratification; Annual Report to the Nation shows that mortality and incidence for most cancers continue to decline
NCI Press Release
(Posted: 03/30/2015) - For the first time, researchers have used national data to determine the incidence of the four major molecular subtypes of breast cancer by age, race/ethnicity, poverty level, and several other factors. The report showed continuing declines in cancer deaths for both men and women, for children, and for nearly all major cancer sites.
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Vanderbilt researchers find that docking stations on chromosomes could be a new anti-cancer target
NCI Cancer Center News
(Posted: 03/27/2015) - Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks.

Hopkins researchers find that MRI based on a sugar molecule can tell cancerous from noncancerous cells
NCI Cancer Center News
(Posted: 03/27/2015) - Results of a study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.

St. Jude researchers find that measuring treatment response proves to be a powerful tool for guiding leukemia treatment
NCI Cancer Center News
(Posted: 03/23/2015) - Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.

Indicators related to lung cancer recurrence, metastases and survival can inform treatment of patients
NCI News Note
(Posted: 03/23/2015) - This study describes prognostic factors for lung cancer spread and recurrence, as well as subsequent risk of death from the disease. The investigators observed that regardless of cancer stage, grade, or type of lung cancer, patients in the study were more likely to have distant metastasis than local recurrence.

Washington U researchers find that kidney cancer could be detected early with urine test
NCI Cancer Center News
(Posted: 03/19/2015) - Washington University School of Medicine researchers have developed a noninvasive method to screen for kidney cancer by measuring the presence of proteins in the urine.

St. Jude scientists trace genomic evolution of high-risk leukemia
NCI Cancer Center News
(Posted: 03/19/2015) - Whole exome sequencing of 20 pediatric ALL patients yielded important insights into the genetic basis of ALL treatment failure.

Dartmouth doctors say women with atypia or DCIS should seek second opinions after breast biopsies
NCI Cancer Center News
(Posted: 03/19/2015) - While doctors almost always agree on a pathological diagnosis of invasive breast cancer, there is room for improvement when diagnosing atypia (or atypical ductal hyperplasia-ADH) and DCIS (ductal carcinoma in-situ).

U of Michigan study suggests precision medicine for adrenal cancer
NCI Cancer Center News
(Posted: 03/19/2015) - In a randomized phase 3 trial, adrenal cancer patients receiving the investigational drug linsitinib fared no better than patients receiving a placebo.

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