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A higher than expected fraction of adolescent osteosarcoma patients carry a gene mutation that is often inherited
NCI Press Release
(Posted: 04/20/2015) - A new study shows that inherited variations in a known tumor suppressor gene among children and adolescents with osteosarcoma, a cancer of the bone, are more common than previously thought.

Researchers report initial feasibility of identifying patients who are exceptional responders to cancer therapy
NCI News Note
(Posted: 04/19/2015) - A pilot study evaluating identification of cancer patients who respond to treatment that is ineffective in at least 90 percent of patients found that it was indeed able to confirm a majority of proposed patients as exceptional responders based on clinical data submitted for consideration. Being able to identify which patients are actual exceptional responders is an important step in determining why these patients respond so uniquely.

UNC researchers find new approach to treat drug-resistant HER2-positive breast cancer
NCI Cancer Center News
(Posted: 04/10/2015) - Using human cancer cell lines, scientists identified various ways that HER2-positive breast cancer tumors resist therapy, and they discovered a potential combination therapy to overcome multiple mechanisms of resistance and kill cancer cells.

UNC study finds that lower survival rates are connected with high-risk melanoma with mutations
NCI Cancer Center News
(Posted: 04/10/2015) - A UNC Lineberger-led study found that people with higher-risk melanoma containing either BRAF or NRAS gene mutations had lower survival rates.

UTSW researchers lead collaborative charge to uncover genetic diversity of pancreatic cancer
NCI Cancer Center News
(Posted: 04/09/2015) - A genetic analysis suggests that most pancreatic cancers harbor genetic alterations that could be targeted by existing drugs, using their genetic features as a roadmap for treatment.

UPenn study shows risk of breast and ovarian cancer may differ by type of BRCA1, BRCA2 mutation
NCI Cancer Center News
(Posted: 04/08/2015) - In a study involving more than 31,000 women with cancer-causing mutations in the BRCA1 or BRCA2 genes, researchers identified mutations that are associated with significantly different risks of breast and ovarian cancers.

MIT researchers describe using sound waves to detect rare cancer cells
NCI Cancer Center News
(Posted: 04/07/2015) - A team of engineers is developing a novel way to isolate circulating tumor cells: using sound waves to separate them from blood cells.

UCLA researchers find that income inequality affects who gets an underutilized breast cancer test
NCI Cancer Center News
(Posted: 04/07/2015) - Wealthier women who live in communities with the greatest income divide between rich and poor had better access to a new genetic test that can determine the most effective form of treatment for early-stage breast cancer, according to a new study.

Northwestern, St Jude and NCI researchers find that childhood cancer survivors face chronic health problems
NCI Cancer Center News
(Posted: 04/06/2015) - The number of childhood cancer survivors in the U.S. has increased, but the majority of those who have survived five or more years after diagnosis face chronic health problems related to their treatment.

Study reports peak longevity benefit with an hour of daily exercise
NCI News Note
(Posted: 04/06/2015) - People who engage in three to five times the recommended minimum level of leisure-time physical activity derive the greatest benefit in terms of mortality reduction when compared with people who do not engage in leisure-time physical activity.

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