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Vanderbilt researchers find that an enzyme affects tumor metastasis
NCI Cancer Center News
(Posted: 01/09/2015) - Researchers have established a role for MMP2 in the development of lung metastases from primary breast cancer. Using mice without the Mmp2 gene, the team found that metastatic tumors in the lung proliferate less in the absence of fibroblast MMP2.

Hopkins researchers find that high-dose testosterone therapy helps some men with advanced prostate cancer
NCI Cancer Center News
(Posted: 01/08/2015) - The male hormone testosterone, generally thought to be a feeder of prostate cancer, has been found to suppress some advanced prostate cancers and also may reverse resistance to testosterone-blocking drugs used to treat prostate cancer.

Dana-Farber researchers find that combined therapy can reduce chance of recurrence in women with small, HER2+ breast tumors
NCI Cancer Center News
(Posted: 01/08/2015) - Dana-Farber researchers report women with small, HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were highly unlikely to have the cancer recur within three years.

Ohio State study suggests that dopamine is a safe anti-angiogenic drug in cancer treatment
NCI Cancer Center News
(Posted: 01/07/2015) - A new study led by scientists at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) suggests that dopamine – an inexpensive drug currently used to treat heart, vascular and kidney disorders – can be safely used in cancer treatment to curb the growth of blood vessels in tumors.

Wash U-led study finds targeting fatty acids may be treatment strategy for arthritis, leukemia
NCI Cancer Center News
(Posted: 01/07/2015) - Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, potentially opening up new avenues for treating these diverse diseases, according to new research at Washington University School of Medicine in St. Louis.

Thomas Jefferson University study shows that a simple technique may be most effective in preventing heart disease after radiation therapy for breast cancer
NCI Cancer Center News
(Posted: 01/06/2015) - New research shows a woman who holds her breath during radiation pulses can greatly reduce radiation exposure to the heart.

UPenn researchers find radiation plus hormone therapy prolongs survival for older men with prostate cancer
NCI Cancer Center News
(Posted: 01/06/2015) - Adding radiation treatment to hormone therapy saves more lives among older men with locally advanced prostate therapy than hormone therapy alone, according to a new study in the Journal of Clinical Oncology this week from Penn Medicine researchers.

Hopkins researchers find cancer is caused mainly by random mutations that occur during cell division
NCI Cancer Center News
(Posted: 01/05/2015) - Scientists from the Johns Hopkins Kimmel Cancer Center have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused mainly by random mutations that occur when stem cells divide.

Hopkins researchers find that risk for leukemia after treatment for early-stage breast cancer higher than reported
NCI Cancer Center News
(Posted: 12/24/2014) - The risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer remains very small, but it is twice as high as previously reported.

A key molecular defect in a childhood gastrointestinal tumor may have important diagnostic implications
NCI News Note
(Posted: 12/24/2014) - NCI scientists have identified a key molecular defect in a tumor in children known as gastrointestinal stromal tumor, or GIST, that may have important diagnostic implications.

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