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Risk factors identified for certain lymphoma subtypes
NCI News Note
(Posted: 09/02/2014) - In a large international collaborative analysis of risk factors for non-Hodgkin lymphoma (NHL), scientists were able to quantify risk associated with medical history, lifestyle factors, family history of blood or lymph-borne cancers, and occupation for 11 different NHL subtypes, including less common subtypes.

Mass General researchers find that circulating tumor cell clusters are more likely to cause metastasis than single cells
NCI Cancer Center News
(Posted: 08/29/2014) - Tumor cells that break off a primary tumor and are carried through the bloodstream appear to be much more likely to cause metastasis than are single circulating tumor cells, according to a study from investigators at the Massachusetts General Hospital Cancer Center.

UC Davis researchers find that nanoparticles could provide applications to diagnose, treat cancer
NCI Cancer Center News
(Posted: 08/27/2014) - Researchers have created dynamic nanoparticles that could provide an arsenal of applications to diagnose and treat cancer.

Hopkins researchers find that cancer leaves a common fingerprint on DNA
NCI Cancer Center News
(Posted: 08/27/2014) - In a study of a broad variety of cancers, investigators say they have found widespread and distinctive changes to chemical marks known as methyl groups attached to DNA. Those marks help govern whether genes are turned “on” or “off,” and ultimately how the cell behaves.

In a study in nematode worms, Duke scientists uncover potential navigation system used by cancer, nerve cells
NCI Cancer Center News
(Posted: 08/26/2014) - Using nemotode worms, Duke University researchers have found a ”roving detection system” on the surface of cells that may point to new ways of treating diseases like cancer, Parkinson's disease and amyotrophic lateral sclerosis.

Northwestern researchers identify marker in aggressive breast cancer
NCI Cancer Center News
(Posted: 08/25/2014) - Two Northwestern University scientists have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy.

UCSD researchers report on new mouse model that points to therapy for liver disease
NCI Cancer Center News
(Posted: 08/22/2014) - Development of effective new therapies for preventing or treating non-alcoholic fatty liver disease has been stymied by limited small animal models for the disease. In a paper published online in Cancer Cell, scientists at the University of California, San Diego School of Medicine describe a novel mouse model that closely resembles human NASH and use it to demonstrate that interference with a key inflammatory protein inhibits both the development of NASH and its progression to liver cancer.

Huntsman researchers outline possible next generation of chronic myeloid leukemia treatment
NCI Cancer Center News
(Posted: 08/21/2014) - A new study that identified mutated forms of a gene that encodes for mutated forms of CML.

Columbia University researchers find that severing nerves in mice may shrink stomach cancers
NCI Cancer Center News
(Posted: 08/21/2014) - Research from Columbia University Medical Center shows that nerves may play a critical role in stomach cancer growth and that blocking nerve signals using surgery or Botox (onabotulinumtoxinA) could be an effective treatment for the disease.

Rare kidney tumor provides insights on role of metabolic changes in cancer
NCI News Note
(Posted: 08/21/2014) - Researchers in The Cancer Genome Atlas (TCGA) Network have uncovered a number of new findings about the biology and development of a rare form of kidney cancer. They found that the disease – chromophobe renal cell carcinoma – stems in part from alterations in genes in the mitochondria, the cell’s energy supplier.

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