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Dana-Farber researchers find that a new agent causes small cell lung tumors to shrink in pre-clinical testing
NCI Cancer Center News
(Posted: 12/09/2014) - Small cell lung cancer has shown itself vulnerable to an agent that disables part of tumor cells’ basic survival machinery, researchers at Dana-Farber Cancer Institute and the Massachusetts Institute of Technology reported.

Dana-Farber researchers find that a narrow subset of cells is responsible for metastasis in multiple myeloma
NCI Cancer Center News
(Posted: 12/08/2014) - Dana-Farber researchers report that multiple myeloma is driven to spread by a subset of the myeloma cells within a patient’s body, and that attacking those specific subsets with targeted drugs may be better targets for therapy.

Dana-Farber researchers report immunotherapy results in patients with Hodgkin lymphoma
NCI Cancer Center News
(Posted: 12/08/2014) - Eighty-seven percent of Hodgkin lymphoma patients who participated in an early-phase immunotherapy clinical trial experienced cancer remission.

Mayo researchers see benefit in test of three-drug treatment for multiple myeloma
NCI Cancer Center News
(Posted: 12/08/2014) - In the treatment of multiple myeloma, the addition of carfilzomib to a currently accepted two-drug combination produced significantly better results than using the two drugs alone, according to a worldwide research team led by investigators from Mayo Clinic.

Duke researchers find that older breast cancer patients still get radiation despite limited benefit
NCI Cancer Center News
(Posted: 12/08/2014) - Women over the age of 70 who have certain early-stage breast cancers overwhelmingly receive radiation therapy despite published evidence that the treatment has limited benefit, researchers at Duke Medicine report.

Georgetown U researchers find that an agent prevents prostate cancer growth and spread in mouse studies
NCI Cancer Center News
(Posted: 12/08/2014) - Researchers have shown that an experimental agent prevents tumor growth and spread in mice with prostate cancer harboring a common chromosomal abnormality.

Baylor scientists find that wound response of cancer stem cells may explain chemo-resistance in bladder cancer
NCI Cancer Center News
(Posted: 12/04/2014) - A novel mechanism -- similar to how normal tissue stem cells respond to wounding -- might explain why bladder cancer stem cells actively contribute to chemo-resistance after multiple cycles of chemotherapy drug treatment.

Personalized vaccines could change how we fight cancer
NCI Cancer Center News
(Posted: 12/03/2014) - In the near future, physicians may treat some cancer patients with personalized vaccines that spur their immune systems to attack malignant tumors. New research led by scientists at Washington University School of Medicine in St. Louis has brought the approach one step closer to reality.

U of Michigan research links antacids to possible better survival in head and neck cancer
NCI Cancer Center News
(Posted: 12/02/2014) - Patients with head and neck cancer who used antacid medicines to control acid reflux had better overall survival, according to a new study from the University of Michigan Comprehensive Cancer Center.

NCI establishes Genomic Data Commons to facilitate identification of molecular subtypes of cancer and potential drug targets
NCI News Note
(Posted: 12/02/2014) - NCI is establishing the Genomic Data Commons to store, analyze and distribute cancer genomics data generated by NCI and other research organizations. The GDC will provide an interactive system for researchers to access data, with the goal of advancing the molecular diagnosis of cancer and suggest potential therapeutic targets based on genomic information.

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