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U of Chicago researchers find that STING pathway could be key to tumor immunity
NCI Cancer Center News
(Posted: 11/21/2014) - A protein complex known as STING plays a crucial role in detecting the presence of tumor cells and promoting an aggressive anti-tumor response by the body's innate immune system, according to two separate studies in Immunity.

Dana-Farber researchers and colleagues find that antiangiogenic treatment improves survival in animal model of ovarian cancer
NCI Cancer Center News
(Posted: 11/21/2014) - Coupling an antiangiogenic treatment with low-dose chemotherapy results in improved survival rates in an animal model of ovarian cancer.

Salk scientists deliver a promising one-two punch for lung cancer in mice
NCI Cancer Center News
(Posted: 11/21/2014) - Scientists at the Salk Institute have discovered a one-two punch for countering a common genetic mutation that often leads to drug-resistant cancers in mice.

Possible power behind 'master' gene for cancer discovered
NCI Cancer Center News
(Posted: 11/21/2014) - There are similarities between bean sprouts and human cancer. The same mechanisms that result in bigger bean sprouts also cause cancer metastasis and tumor development.

Baylor scientists find that TopBP1 is a sweet spot for treatment in multiple cancers
NCI Cancer Center News
(Posted: 11/18/2014) - A compound called calcein may act to inhibit topoisomerase IIBeta-binding protein 1 (TopBP1), which enhances the growth of tumors, said researchers from Baylor College of Medicine.

Stanford researchers find that a noncoding RNA promotes pediatric bone cancer
NCI Cancer Center News
(Posted: 11/18/2014) - A new study in the Journal of Clinical Investigation indicates that a long non-coding RNA named Ewing sarcoma-associated transcript 1 contributes to the complex network of changes that occur in Ewing Sarcoma.

Northwestern U scientists develop genetic-based tool to detect circulating cancer cells in blood
NCI Cancer Center News
(Posted: 11/18/2014) - Northwestern University scientists have demonstrated a genetic-based approach that is able to detect live circulating tumor cells out of the complex matrix that is human blood.

Mayo researchers find that an investigational oral drug combo shows promise for newly diagnosed multiple myeloma
NCI Cancer Center News
(Posted: 11/18/2014) - The investigational drug ixazomib taken orally in combination with lenalidomide and dexamethasone shows promise in patients with newly diagnosed multiple myeloma.

Northwestern U researchers mouse study finds potential therapy for incurable pediatric brain tumor
NCI Cancer Center News
(Posted: 11/18/2014) - Northwestern University scientists have discovered a new potential drug therapy in mice for a rare, incurable pediatric brain tumor by targeting a genetic mutation found in children with the cancer.

MD Anderson researchers find that metabolic reprogramming by the p53 gene family leads to tumor regression
NCI Cancer Center News
(Posted: 11/18/2014) - Scientists have found that altering members of the p53 gene family, known as tumor suppressor genes, causes rapid regression of tumors that are deficient in or totally missing p53.

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