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MD Anderson researchers discover gene that might predict aggressive prostate cancer at diagnosis
NCI Cancer Center News
(Posted: 10/03/2014) - Researchers at The University of Texas MD Anderson Cancer Center have identified a biomarker living next door to the KLK3 gene that could predict which GS7 prostate cancer patients will have a more aggressive form of cancer.

MD Anderson study indicates possible new way to treat endometrial, colon cancers
NCI Cancer Center News
(Posted: 10/03/2014) - A study led by researchers at MD Anderson Cancer Center points to cellular mutations in the gene PIK3R1 which activate ERK and JNK, thus allowing tumor growth.

NCI scientists find protective mechanism against cancer in the cells of progeria patients
NCI News Note
(Posted: 10/02/2014) - NCI scientists have studied cells of patients with an extremely rare genetic disease that is characterized by drastic premature aging and discovered a new protective cellular mechanism against cancer. They found that cells from patients with Hutchinson Gilford Progeria Syndrome (HGPS), who typically do not develop cancer, contain a tumor protection mechanism that is mediated by BRD4.

Georgetown researchers find that landmark Medicare law had little impact on reducing chemotherapy cost
NCI Cancer Center News
(Posted: 09/30/2014) - Legislation passed in 2003 to slow the spiraling costs of drugs paid for by the federal government to treat Medicare patients has had no meaningful impact on cancer chemotherapy drug costs, say a team of researchers in the Journal of Clinical Oncology published online today.

Dana-Farber researchers identify early sign of pancreatic cancer
NCI Cancer Center News
(Posted: 09/29/2014) - Scientists at Dana-Farber Cancer Institute, the Massachusetts Institute of Technology, and other institutions have discovered a sign of the early development of pancreatic cancer – an upsurge in certain amino acids that occurs before the disease is diagnosed and symptoms appear.

Massachusetts General researchers find treatment is effective against ROS1-positive lung cancer in a small trial
NCI Cancer Center News
(Posted: 09/29/2014) - Treatment with the targeted therapy drug crizotinib effectively halted the growth of lung tumors driven by rearrangements of the ROS1 gene in a small clinical trial.

Researchers at Broad Institute and MIT engineer "Cas9" animal models to study disease and inform drug discovery
NCI Cancer Center News
(Posted: 09/26/2014) - Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments.

Dana-Farber researchers find that a novel compound prevents metastasis of multiple myeloma in mouse studies
NCI Cancer Center News
(Posted: 09/26/2014) - In a significant advance against the problem of cancer metastasis, Dana-Farber Cancer Institute scientists have shown that a specially developed compound can impede multiple myeloma from spreading to the bones in mice. The findings, published in the Sept. 25 issue of Cell Reports, suggest the technique can protect human patients, as well, from one of the most deadly aspects of cancer.

USC researchers find that a single genetic change can cause cancerous tumors in a child’s eyes
NCI Cancer Center News
(Posted: 09/25/2014) - Researchers have answered the long-standing question of why mutations to a particular gene primarily cause tumors of the retina and not of other cell types. Led by experts at the USC Eye Institute, the study could reveal new cellular signaling pathways relevant to retinal development, cancer development and the development of novel therapies.

Vanderbilt study questions accuracy of lung cancer screens in some geographic regions
NCI Cancer Center News
(Posted: 09/24/2014) - A new analysis of published studies found that FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common.

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