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Roswell Park researchers identify priority targets for immunotherapy in epithelial ovarian cancer
NCI Cancer Center News
(Posted: 08/14/2014) - Researchers at Roswell Park Cancer Institute have found that the expression pattern of a unique class of tumor-associated antigens, known as the MAGE cancer-testis antigens, correlates with clinical outcome in epithelial ovarian cancer.

Hopkins researchers find that injected bacteria can shrink tumors in rats, dogs and humans
NCI Cancer Center News
(Posted: 08/14/2014) - A modified version of the Clostridium novyi bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report from Johns Hopkins Kimmel Cancer Center researchers.

Stanford researchers uncover cancer-causing mechanism in mice that is also behind powerful human oncogene
NCI Cancer Center News
(Posted: 08/12/2014) - Suppressing the expression of just five genes can mimic the effect of a powerful cancer-causing protein called Myc.

UT Southwestern mouse study pinpoints gene likely to promote childhood cancers
NCI Cancer Center News
(Posted: 08/12/2014) - A study conducted with mice was designed to model childhood cancers. If the findings prove to be applicable to humans, the research could lead to new strategies for targeting certain childhood cancers at a molecular level.

UCSD mouse study looks at how breast cancer usurps the powers of mammary stem cells
NCI Cancer Center News
(Posted: 08/12/2014) - Scientists at the University of California, San Diego School of Medicine and Moores Cancer Center have found that mammary stem cells associated with the pregnant mammary gland are related to stem cells found in breast cancer.

The benefits of looking across many cancer genomes: A perspective
NCI Perspective
(Posted: 09/27/2013, Updated: 08/12/2014) - Cancer is not a single entity, but rather, it is more than one hundred complex and distinct diseases, with most cancer types demanding a unique treatment strategy. TCGA researchers have developed a formal project for a cross tumor analysis, called Pan-Cancer. Its goal is to assemble TCGA’s wealth of data across tumor types, analyze and interpret those data, and finally, make both the analyses and the data freely available.

Duke research delves into editing HPV's genes to kill cervical cancer cells
NCI Cancer Center News
(Posted: 08/11/2014) - Using the genome editing tool known as CRISPR, Duke University researchers were able to selectively destroy two viral genes responsible for the growth and survival of cervical carcinoma cells, causing the cancer cells to self-destruct.

MIT researchers find a new way to model cancer using mice
NCI Cancer Center News
(Posted: 08/07/2014) - One way to discover the role of the mutations is to breed a strain of mice that carry the genetic flaw — but breeding such mice is an expensive, time-consuming process. Now, MIT researchers have found an alternative.

University of Michigan researchers find that gut microbiome analysis improved noninvasive colorectal cancer screening
NCI Cancer Center News
(Posted: 08/07/2014) - Analysis of the gut microbiome more successfully distinguished healthy individuals from those with precancerous adenomatous polyps and those with invasive colorectal cancer compared with assessment of clinical risk factors and fecal occult blood testing.

Stanford researchers find that rare developmental disorder is linked to tumor-suppressing protein
NCI Cancer Center News
(Posted: 08/04/2014) - Researchers have revealed a new insight into CHARGE syndrome, a rare developmental disorder.

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