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Dartmouth researchers develop approach to chronic lymphocytic leukemia treatment
NCI Cancer Center News
(Posted: 03/17/2014) - Dartmouth researchers have developed a different approach to treating Chronic Lymphocytic Leukemia (CLL), a form of blood cancer that often requires repeated chemotherapy treatments to which it grows resistant.

Dana-Farber study of genomic testing links 'exceptional' drug response to rare mutations in bladder cancer
NCI Cancer Center News
(Posted: 03/13/2014) - A patient with advanced bladder cancer, who was part of a phase 1 clinical trial, had a complete response for 14 months to a combination of the targeted drugs everolimus and pazopanib.

Stanford study finds that whole-genome sequencing for clinical use faces many challenges
NCI Cancer Center News
(Posted: 03/12/2014) - Whole-genome sequencing is a powerful technology, but a new Stanford study shows that significant challenges must be overcome before it can be routinely clinically useful.

Harvard researchers find that a common mutation is culprit in acute leukemia relapse
NCI Cancer Center News
(Posted: 03/10/2014) - Harvard stem cell scientists have identified a mutation in human cases of acute lymphoblastic leukemia that likely drives relapse.

UCSF study says E-cigarettes are a possible gateway to nicotine addiction for U.S. teens
NCI Cancer Center News
(Posted: 03/10/2014) - E-cigarettes, promoted as a way to quit regular cigarettes, may actually be a new route to conventional smoking and nicotine addiction for teenagers, according to a new UC San Francisco study.

UCSD researchers find that anti-psychotic medications offer new hope in the battle against glioblastoma
NCI Cancer Center News
(Posted: 03/10/2014) - Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma.

UTSW researchers identify target for shutting down growth of prostate cancer cells
NCI Cancer Center News
(Posted: 03/10/2014) - Dr. Ralf Kittler's lab found that an enzyme called USP9X protects ERG from degradation in prostate cancer cells and subsequently found that a molecule called WP1130 can block USP9X and lead to the destruction of ERG.

Harvard study finds that younger men benefit most from surgery for localized prostate cancer
NCI Cancer Center News
(Posted: 03/06/2014) - New study finds a substantial long-term reduction in mortality for men with localized cancer who undergo a radical prostatectomy.

Hopkins and Dana-Farber researchers report that immune system-based therapy produces lasting remissions in melanoma patients
NCI Cancer Center News
(Posted: 03/06/2014, Updated: 03/06/2014) - Nivolumab, a drug that unleashes the immune system to attack cancer, is now shown to produce lasting remissions and hold the disease in check in many patients with advanced melanoma.

Dana-Farber study shows more hospital deaths and invasive care for dying cancer patients who receive chemotherapy
NCI Cancer Center News
(Posted: 03/05/2014) - Terminal cancer patients who receive chemotherapy in the last months of their lives are less likely to die where they want and are more likely to undergo invasive medical procedures than those who do not receive chemotherapy.

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