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Washington U researchers find that personalized melanoma vaccines may marshal an immune response
NCI Cancer Center News
(Posted: 04/03/2015) - Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of Medicine in St. Louis.

NYU researchers identify mechanism in tumor-cell proliferation in pediatric bone cancers
NCI Cancer Center News
(Posted: 04/02/2015) - A particular molecular pathway permits stem cells in pediatric bone cancers to grow rapidly and aggressively, according to researchers.

MIT researchers find new evidence for how a rare form of liver cancer arises
NCI Cancer Center News
(Posted: 04/02/2015) - Using new sequencing technology that enables large-scale analysis of DNA damage-associated mutations, MIT researchers have pinpointed the specific type of DNA damage that may be responsible for this mutation.

Douglas Lowy named Acting Director of the National Cancer Institute
NCI Press Release
(Posted: 04/01/2015) - Douglas Lowy, M.D., today was officially named the National Cancer Institute’s Acting Director. Dr. Lowy, a cancer researcher for more than 40 years, received the National Medal of Technology and Innovation from President Obama in 2014 for his research that led to the development of the human papillomavirus (HPV) vaccine.

Circulating tumor DNA in blood can predict recurrence of the most common type of lymphoma
NCI Press Release
(Posted: 04/01/2015) - Measurement of circulating tumor DNA in blood can be used to detect disease recurrence in patients with a curable form of cancer known as diffuse large B-cell lymphoma (DLBCL). In most patients, measurement of ctDNA enabled detection of microscopic disease before it could be seen on computerized tomography scans.

U of Michigan researchers develop new potential drug for rare leukemia
NCI Cancer Center News
(Posted: 03/31/2015) - Researchers at the University of Michigan Comprehensive Cancer Center have developed a new drug candidate that shows potential in laboratory studies against a rare type of acute leukemia.

New analysis of breast cancer subtypes could lead to better risk stratification; Annual Report to the Nation shows that mortality and incidence for most cancers continue to decline
NCI Press Release
(Posted: 03/30/2015) - For the first time, researchers have used national data to determine the incidence of the four major molecular subtypes of breast cancer by age, race/ethnicity, poverty level, and several other factors. The report showed continuing declines in cancer deaths for both men and women, for children, and for nearly all major cancer sites.
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Vanderbilt researchers find that docking stations on chromosomes could be a new anti-cancer target
NCI Cancer Center News
(Posted: 03/27/2015) - Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks.

Hopkins researchers find that MRI based on a sugar molecule can tell cancerous from noncancerous cells
NCI Cancer Center News
(Posted: 03/27/2015) - Results of a study suggest that MRI could one day make biopsies more effective or even replace them altogether by noninvasively detecting telltale sugar molecules shed by the outer membranes of cancerous cells.

St. Jude researchers find that measuring treatment response proves to be a powerful tool for guiding leukemia treatment
NCI Cancer Center News
(Posted: 03/23/2015) - Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.

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