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Implementation of the NCI’s National Clinical Trials Network
NCI Perspective Article
(Posted: 03/20/2014) - NCI is launching a new clinical trials research network intended to improve treatment for the more than 1.6 million Americans diagnosed with cancer each year. The new system, NCI’s National Clinical Trials Network (NCTN), will facilitate the rapid initiation and completion of cancer clinical trials at over 3,000 clinical trials sites.
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Case Western researchers use big data to identify triple-negative breast, oropharyngeal, and lung cancers
NCI Cancer Center News
(Posted: 03/19/2014) - Researchers at Case Western Reserve University and colleagues used big data analytics to predict if a patient is suffering from aggressive triple-negative breast cancer, slower-moving cancers or non-cancerous lesions with 95 percent accuracy.

St. Jude researchers find that health gap between adult survivors of childhood cancer and siblings widens with age
NCI Cancer Center News
(Posted: 03/18/2014) - Long-term follow-up of adult survivors of childhood cancer reinforces need for lifelong health surveillance for childhood cancer survivors.

Dartmouth researchers develop approach to chronic lymphocytic leukemia treatment
NCI Cancer Center News
(Posted: 03/17/2014) - Dartmouth researchers have developed a different approach to treating Chronic Lymphocytic Leukemia (CLL), a form of blood cancer that often requires repeated chemotherapy treatments to which it grows resistant.

Dana-Farber study of genomic testing links 'exceptional' drug response to rare mutations in bladder cancer
NCI Cancer Center News
(Posted: 03/13/2014) - A patient with advanced bladder cancer, who was part of a phase 1 clinical trial, had a complete response for 14 months to a combination of the targeted drugs everolimus and pazopanib.

Stanford study finds that whole-genome sequencing for clinical use faces many challenges
NCI Cancer Center News
(Posted: 03/12/2014) - Whole-genome sequencing is a powerful technology, but a new Stanford study shows that significant challenges must be overcome before it can be routinely clinically useful.

Harvard researchers find that a common mutation is culprit in acute leukemia relapse
NCI Cancer Center News
(Posted: 03/10/2014) - Harvard stem cell scientists have identified a mutation in human cases of acute lymphoblastic leukemia that likely drives relapse.

UCSF study says E-cigarettes are a possible gateway to nicotine addiction for U.S. teens
NCI Cancer Center News
(Posted: 03/10/2014) - E-cigarettes, promoted as a way to quit regular cigarettes, may actually be a new route to conventional smoking and nicotine addiction for teenagers, according to a new UC San Francisco study.

UCSD researchers find that anti-psychotic medications offer new hope in the battle against glioblastoma
NCI Cancer Center News
(Posted: 03/10/2014) - Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma.

UTSW researchers identify target for shutting down growth of prostate cancer cells
NCI Cancer Center News
(Posted: 03/10/2014) - Dr. Ralf Kittler's lab found that an enzyme called USP9X protects ERG from degradation in prostate cancer cells and subsequently found that a molecule called WP1130 can block USP9X and lead to the destruction of ERG.

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