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Albert Einstein Cancer Center study finds that a new test predicts if breast cancer will spread
NCI Cancer Center News
(Posted: 06/04/2014) - A test that counts the number of locations in tumor specimens where tumor cells may invade blood vessels predicted the risk of distant spread, or metastasis, for the most common type of breast cancer.

NCI and NCI-supported researchers use crowdsourcing to answer cancer cell drug sensitivities questions
NCI Cancer Center News
(Posted: 06/03/2014) - NCI and NCI-supported scientists characterized molecular markers in cancer, which can then be tested against large collections of human samples, such as those of The Cancer Genome Atlas.

Dartmouth researchers find that a mutation to BRCA2 gene can double the risk of lung cancer in smokers
NCI Cancer Center News
(Posted: 06/03/2014) - New research by an international group of scientists confirms a vulnerability to lung cancer can be inherited and implicates the BRCA2 gene as harboring one of the involved genetic mutations.

Dana-Farber study suggests that expanded health coverage may improve cancer outcomes in young adults
NCI Cancer Center News
(Posted: 06/03/2014) - Researchers find young adults who lack health care insurance are more likely to be diagnosed in advanced stages of cancer and have a higher risk of death.

Huntsman researchers find that reduced kidney function is associated with higher risk of renal and urothelial cancer
NCI Cancer Center News
(Posted: 06/02/2014) - Researchers who investigated the level of kidney function and subsequent cancer risk in more than one million adults have found that reduced glomerular filtration rate is a key measure of reduced kidney function and chronic kidney disease is an independent risk factor for renal and urothelial cancer but not other cancer types.

Duke researchers identify new brain cancer mutation that will aid drug development
NCI Cancer Center News
(Posted: 06/02/2014) - A collaborative effort between Duke Medicine researchers and neurosurgeons and scientists in China has produced new genetic insights into a rare and deadly form of childhood and young adult brain cancer called brainstem glioma.

NCI at ASCO: A brief overview on research in women's cancers
NCI Perspective Article
(Posted: 06/02/2014) - The 2014 annual American Society of Clinical Oncology (ASCO) meeting in Chicago in June highlighted results from a number of NCI-supported and -sponsored clinical trial results in women’s cancers. Taken together, these results represent important advances in our understanding of how to treat these diseases and improve the lives of those living with them.
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New treatment option for young women with hormone-sensitive breast cancer
NCI Press Release
(Posted: 06/01/2014) - A drug used for treating breast cancer, known as exemestane, is more effective than a common breast cancer prevention drug, tamoxifen, in preventing breast cancer recurrence in young women who also receive post-surgical treatment to suppress ovarian function. The combined results of the Tamoxifen and Exemestane Trial and Suppression of Ovarian Function Trial were presented at the 2014 ASCO Annual Meeting in Chicago.
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NIH-funded study shows increased survival in men with metastatic prostate cancer who receive chemotherapy when starting hormone therapy
NCI Press Release
(Posted: 12/05/2013, Updated: 06/01/2014) - Men with hormone-sensitive metastatic prostate cancer who received the chemotherapy drug docetaxel given at the start of standard hormone therapy lived longer than patients who received hormone therapy alone, according to early results from a NIH-supported randomized controlled clinical trial.
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Study of targeted therapies for breast cancer established model for global clinical trials
(Posted: 02/29/2008, Updated: 06/01/2014) - Two targeted medications designed to treat an aggressive form of breast cancer were tested in a study that involved 8,000 participants in 44 countries. While the purpose of this trial was to enable researchers to determine whether dual targeted treatment of early stage HER2-positive breast cancer was better than using a single agent against HER2-positive disease, results of this trial did not show a benefit for women taking the drug combination of trastuzumab or lapatinib. The trial however, did provide a new model for global cancer research and collaboration.
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